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Select item 114472561.

Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer

Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y

PMCID:: PMC11447256

Abstract Article PDF–2.8M

Select item 112099352.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 110732363.

G-quadruplex structural dynamics at MAPK12 promoter dictates transcriptional switch to determine stemness in breast cancer

Pallabi Sengupta, Anindya Dutta, Y. V. Suseela, Tanaya Roychowdhury, Nilanjan Banerjee, Ananya Dutta, Satyajit Halder, Kuladip Jana, Gopeswar Mukherjee, Samit Chattopadhyay, Thimmaiah Govindaraju, Subhrangsu Chatterjee

Cell Mol Life Sci. 2024 Dec; 81(1): 33. Published online 2024 Jan 12. doi: 10.1007/s00018-023-05046-6

PMCID:: PMC11073236

Abstract Article PDF–6.7M

Select item 110341844.

Different regulation of PKC isoenzymes and MAPK by PSK and IL-2 in the proliferative and cytotoxic activities of the NKL human natural killer cell line

Angel García-Lora, Marisol Martinez, Susana Pedrinaci, Federico Garrido

Cancer Immunol Immunother. 2003 Jan; 52(1): 59–64. Published online 2002 Oct 17. doi: 10.1007/s00262-002-0336-9

PMCID:: PMC11034184

Abstract Article PDF–327K

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102021836.

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage

Fengli Wang, Lingjuan Wang, Shiming Gan, Shenglei Feng, Sijin Ouyang, Xiaoli Wang, Shuiqiao Yuan

Research (Wash D C) 2023; 6: 0091. Published online 2023 Apr 12. doi: 10.34133/research.0091

PMCID:: PMC10202183

Abstract Article PDF–18M

Select item 92792857.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 88974218.

The pro-tumorigenic activity of p38γ overexpression in nasopharyngeal carcinoma

De-Pei Yin, Yu-Fan Zheng, Peng Sun, Ming-Yu Yao, Li-xiao Xie, Xun-Wu Dou, Ye Tian, Ji-Sheng Liu

Cell Death Dis. 2022 Mar; 13(3): 210. Published online 2022 Mar 4. doi: 10.1038/s41419-022-04637-8

PMCID:: PMC8897421

Abstract Article PDF–5.0M

Select item 88970229.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 889544310.

Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

Sreeram Vallabhaneni, Jian Liu, Marion Morel, Jixin Wang, Francesco J. DeMayo, Weiwen Long

Mol Oncol. 2022 Mar; 16(5): 1184–1199. Published online 2021 Dec 14. doi: 10.1002/1878-0261.13132

PMCID:: PMC8895443

Abstract Article PDF–7.2M

Select item 837899611.

The atypical MAPK ERK3 potently suppresses melanoma cell growth and invasiveness

Minyi Chen, Amanda K. Myers, Michael P. Markey, Weiwen Long

J Cell Physiol. Author manuscript; available in PMC 2021 Aug 20.

Published in final edited form as: J Cell Physiol. 2019 Aug; 234(8): 13220–13232. Published online 2018 Dec 19. doi: 10.1002/jcp.27994

PMCID:: PMC8378996

Abstract Article PDF–4.5M

Select item 831454712.

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang

Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5

PMCID:: PMC8314547

Abstract Article PDF–3.7M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 742732714.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 668424015.

IFNγ-inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5

Diana Saleiro, Gavin T. Blyth, Ewa M. Kosciuczuk, Patrick A. Ozark, Beata Majchrzak-Kita, Ahmet D. Arslan, Mariafausta Fischietti, Neha K. Reddy, Curt M. Horvath, Roger J. Davis, Eleanor N. Fish, Leonidas C. Platanias

Sci Signal. Author manuscript; available in PMC 2019 Nov 20.

Published in final edited form as: Sci Signal. 2018 Nov 20; 11(557): eaap9921. Published online 2018 Nov 20. doi: 10.1126/scisignal.aap9921

PMCID:: PMC6684240

Abstract Article PDF–2.2M

Select item 642845216.

Role of p38γ MAPK in Regulation of EMT and Cancer Stem Cells

Mei Xu, Siying Wang, Yongchao Wang, Huaxun Wu, Jacqueline A Frank, Zhuo Zhang, Jia Luo

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2018 Nov; 1864(11): 3605–3617. Published online 2018 Aug 18. doi: 10.1016/j.bbadis.2018.08.024

PMCID:: PMC6428452

Abstract Article PDF–3.4M

Select item 620093017.

Activation loop phosphorylation of ERK3 is important for its kinase activity and ability to promote lung cancer cell invasiveness

Lobna Elkhadragy, Hadel Alsaran, Marion Morel, Weiwen Long

J Biol Chem. 2018 Oct 19; 293(42): 16193–16205. Published online 2018 Aug 30. doi: 10.1074/jbc.RA118.003699

PMCID:: PMC6200930

Abstract Article PDF–2.2M

Select item 610072418.

Proteome‐wide analysis of phospho‐regulated PDZ domain interactions

Gustav N Sundell, Roland Arnold, Muhammad Ali, Piangfan Naksukpaiboon, Julien Orts, Peter Güntert, Celestine N Chi, Ylva Ivarsson

Mol Syst Biol. 2018 Aug; 14(8): e8129. Published online 2018 Aug 20. doi: 10.15252/msb.20178129

PMCID:: PMC6100724

Abstract Article PDF–2.4M

Select item 567858119.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 567024120.

L290P/V mutations increase ERK3’s cytoplasmic localization and migration/invasion-promoting capability in cancer cells

Hadel Alsaran, Lobna Elkhadragy, Astha Shakya, Weiwen Long

Sci Rep. 2017; 7: 14979. Published online 2017 Nov 3. doi: 10.1038/s41598-017-15135-9

PMCID:: PMC5670241

Abstract Article PDF–4.0M

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