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Items: 1 to 20 of 70

1.
Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation
Jaewon Lee, Jihoon Ha, Jun-Hyeong Kim, Dongyeob Seo, Minbeom Kim, Yerin Lee, Seong Shil Park, Dahee Choi, Jin Seok Park, Young Jae Lee, Siyoung Yang, Kyung-Min Yang, Su Myung Jung, Suntaek Hong, Seung-Hoi Koo, Yong-Soo Bae, Seong-Jin Kim, Seok Hee Park
Exp Mol Med. 2023 Jun; 55(6): 1218–1231. Published online 2023 Jun 1. doi: 10.1038/s12276-023-01009-w
PMCID:
PMC10318043
AbstractArticlePDF–3.0M
2.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
3.
MLK3 Regulates Inflammatory Response via Activation of AP-1 Pathway in HEK293 and RAW264.7 Cells
Anh Thu Ha, Jae Youl Cho, Daewon Kim
Int J Mol Sci. 2022 Sep; 23(18): 10874. Published online 2022 Sep 17. doi: 10.3390/ijms231810874
PMCID:
PMC9501218
AbstractArticlePDF–2.0M
4.
Phosphorylation of mixed lineage kinase MLK3 by cyclin-dependent kinases CDK1 and CDK2 controls ovarian cancer cell division
Luis Cedeno-Rosario, David Honda, Autumn M. Sunderland, Mark D. Lewandowski, William R. Taylor, Deborah N. Chadee
J Biol Chem. 2022 Aug; 298(8): 102263. Published online 2022 Jul 14. doi: 10.1016/j.jbc.2022.102263
PMCID:
PMC9399292
AbstractArticlePDF–3.3M
5.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
6.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
7.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
8.
Mechanisms underlying melanoma invasion as a consequence of MLK3 loss
Henriette U. Balinda, Alanna Sedgwick, Crislyn D’Souza-Schorey
Exp Cell Res. Author manuscript; available in PMC 2023 Jun 1.
Published in final edited form as: Exp Cell Res. 2022 Jun 1; 415(1): 113106. Published online 2022 Mar 18. doi: 10.1016/j.yexcr.2022.113106
PMCID:
PMC9086996
AbstractArticlePDF–2.7M
9.
MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3
Sunil Kumar Singh, Sandeep Kumar, Navin Viswakarma, Daniel R. Principe, Subhasis Das, Gautam Sondarva, Rakesh Sathish Nair, Piush Srivastava, Subhash C. Sinha, Paul J. Grippo, Gregory R. J. Thatcher, Basabi Rana, Ajay Rana
Oncogene. 2021; 40(43): 6153–6165. Published online 2021 Sep 13. doi: 10.1038/s41388-021-02007-w
PMCID:
PMC8553609
AbstractArticlePDF–6.9M
10.
BioID reveals an ATG9A interaction with ATG13‐ATG101 in the degradation of p62/SQSTM1‐ubiquitin clusters
Ashari R Kannangara, Daniel M Poole, Colten M McEwan, Joshua C Youngs, Vajira K Weerasekara, Alex M Thornock, Misael T Lazaro, Eranga R Balasooriya, Laura M Oh, Erik J Soderblom, Jonathan J Lee, Daniel L Simmons, Joshua L Andersen
EMBO Rep. 2021 Oct 5; 22(10): e51136. Published online 2021 Aug 9. doi: 10.15252/embr.202051136
PMCID:
PMC8490997
AbstractArticlePDF–4.5M
11.
LATS1 Regulates Mixed-Lineage Kinase 3 (MLK3) Subcellular Localization and MLK3-Mediated Invasion in Ovarian Epithelial Cells
Srimathi Kasturirangan, Batool Mehdi, Deborah N. Chadee
Mol Cell Biol. 2021 Jul; 41(7): e00078-21. Prepublished online 2021 Apr 19. Published online 2021 Jun 23. doi: 10.1128/MCB.00078-21
PMCID:
PMC8224236
AbstractArticlePDF–2.7M
12.
Mixed Lineage Kinase 3 phosphorylates prolyl-isomerase PIN1 and potentiates GLI1 signaling in pancreatic cancer development
Navin Viswakarma, Gautam Sondarva, Daniel R. Principe, Rakesh Sathish Nair, Sandeep Kumar, Sunil Kumar Singh, Subhasis Das, Subhash C. Sinha, Paul J Grippo, Sam Grimaldo, Pier Cristoforo Giulianotti, Basabi Rana, Ajay Rana
Cancer Lett. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Cancer Lett. 2021 Sep 1; 515: 1–13. Published online 2021 May 27. doi: 10.1016/j.canlet.2021.04.015
PMCID:
PMC8215900
AbstractArticlePDF–2.4M
13.
USP11 mediates repair of DNA–protein cross-links by deubiquitinating SPRTN metalloprotease
Megan Perry, Meghan Biegert, Sai Sundeep Kollala, Halle Mallard, Grace Su, Manohar Kodavati, Natasha Kreiling, Alexander Holbrook, Gargi Ghosal
J Biol Chem. 2021 Jan-Jun; 296: 100396. Published online 2021 Feb 7. doi: 10.1016/j.jbc.2021.100396
PMCID:
PMC7960550
AbstractArticlePDF–1.5M
14.
Mixed Lineage Kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-Activated Kinase 1
Subhasis Das, Rakesh Sathish Nair, Rajakishore Mishra, Gautam Sondarva, Navin Viswakarma, Hazem Abdelkarim, Vadim Gaponenko, Basabi Rana, Ajay Rana
Oncogene. Author manuscript; available in PMC 2020 Oct 17.
Published in final edited form as: Oncogene. 2019 May; 38(19): 3569–3584. Published online 2019 Jan 21. doi: 10.1038/s41388-019-0690-0
Correction in:
Oncogene. 2019 Sep 17
PMCID:
PMC7568686
AbstractArticlePDF–1.8M
15.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
16.
Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity
Sandeep Kumar, Sunil Kumar Singh, Navin Viswakarma, Gautam Sondarva, Rakesh Sathish Nair, Periannan Sethupathi, Subhash C. Sinha, Rajyasree Emmadi, Kent Hoskins, Oana Danciu, Gregory R. J. Thatcher, Basabi Rana, Ajay Rana
Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7961–7970. Published online 2020 Mar 24. doi: 10.1073/pnas.1921325117
PMCID:
PMC7149389
AbstractArticlePDF–2.4M
17.
MLK3 is a newly identified microRNA-520b target that regulates liver cancer cell migration
Fei Zhang, Yu Zhu, Shuhua Wu, Guodong Hou, Nianxiang Wu, Lirun Qian, Dong Yang
PLoS One. 2020; 15(3): e0230716. Published online 2020 Mar 26. doi: 10.1371/journal.pone.0230716
PMCID:
PMC7098554
AbstractArticlePDF–1.2M
18.
IFNγ-inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5
Diana Saleiro, Gavin T. Blyth, Ewa M. Kosciuczuk, Patrick A. Ozark, Beata Majchrzak-Kita, Ahmet D. Arslan, Mariafausta Fischietti, Neha K. Reddy, Curt M. Horvath, Roger J. Davis, Eleanor N. Fish, Leonidas C. Platanias
Sci Signal. Author manuscript; available in PMC 2019 Nov 20.
Published in final edited form as: Sci Signal. 2018 Nov 20; 11(557): eaap9921. Published online 2018 Nov 20. doi: 10.1126/scisignal.aap9921
PMCID:
PMC6684240
AbstractArticlePDF–2.2M
19.
Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3
Malgorzata E. Kokoszka, Stefanie L. Kall, Sehar Khosla, Jennifer E. McGinnis, Arnon Lavie, Brian K. Kay
J Biol Chem. 2018 Aug 31; 293(35): 13553–13565. Published online 2018 Jul 6. doi: 10.1074/jbc.RA117.000262
PMCID:
PMC6120190
AbstractArticlePDF–2.3M
20.
Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells
Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo
Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31
PMCID:
PMC5839158
AbstractArticlePDF–1.9M

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