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Items: 1 to 20 of 24

1.
Deregulation of PRDM5 promotes cell proliferation by regulating JAK/STAT signaling pathway through SOCS1 in human lung adenocarcinoma
Yuanyuan Ren, Ye Wang, Lijiao Fang, Mengchu Ma, Lin Ge, Chao Su, Lingbiao Xin, Jinyan He, Jie Yang, Xin Liu
Cancer Med. 2023 Feb; 12(4): 4568–4578. Published online 2022 Sep 20. doi: 10.1002/cam4.5251
PMCID:
PMC9972168
AbstractArticlePDF–5.4M
2.
Low expression of PRDM5 predicts poor prognosis of esophageal squamous cell carcinoma
Jing Guo, Qiuxing Yang, Sheng Wei, Jingjing Shao, Tianye Zhao, Liyuan Guo, Jia Liu, Jia Chen, Gaoren Wang
BMC Cancer. 2022; 22: 745. Published online 2022 Jul 7. doi: 10.1186/s12885-022-09787-8
PMCID:
PMC9264607
AbstractArticlePDF–2.0M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
5.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
6.
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116
Correction in:
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.
PMCID:
PMC6600915
AbstractArticlePDF–1.7M
7.
Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients
Pallav Bhatnagar, Shirley Purvis, Emily Barron-Casella, Michael R DeBaun, James F Casella, Dan E Arking, Jeffrey R Keefer
J Hum Genet. Author manuscript; available in PMC 2018 Feb 23.
Published in final edited form as: J Hum Genet. 2011 Apr; 56(4): 316–323. Published online 2011 Feb 17. doi: 10.1038/jhg.2011.12
PMCID:
PMC5825003
AbstractArticlePDF–1.5M
8.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
9.
Identification of Prdm genes in human corneal endothelium
Kostadin Rolev, Dominic G. O'Donovan, Christiana Georgiou, Madhavan S. Rajan, Alexandra Chittka
Exp Eye Res. 2017 Jun; 159: 114–122. doi: 10.1016/j.exer.2017.02.009
PMCID:
PMC5451076
AbstractArticle
10.
Whole exome sequencing identifies a heterozygous missense variant in the PRDM5 gene in a family with Axenfeld–Rieger syndrome
Shazia Micheal, Sorath Noorani Siddiqui, Saemah Nuzhat Zafar, Hanka Venselaar, Raheel Qamar, Muhammad Imran Khan, Anneke I. den Hollander
Neurogenetics. 2016; 17: 17–23. Published online 2015 Oct 21. doi: 10.1007/s10048-015-0462-0
PMCID:
PMC4701771
AbstractArticlePDF–634K
11.
Bruch’s membrane abnormalities in PRDM5-related brittle cornea syndrome
Louise F. Porter, Roberto Gallego-Pinazo, Catherine L. Keeling, Martyna Kamieniorz, Nicoletta Zoppi, Marina Colombi, Cecilia Giunta, Richard Bonshek, Forbes D. Manson, Graeme C. Black
Orphanet J Rare Dis. 2015; 10: 145. Published online 2015 Nov 11. doi: 10.1186/s13023-015-0360-4
PMCID:
PMC4642625
AbstractArticlePDF–2.1M
12.
A role for repressive complexes and H3K9 di-methylation in PRDM5-associated brittle cornea syndrome
Louise F. Porter, Giorgio G. Galli, Sally Williamson, Julian Selley, David Knight, Nursel Elcioglu, Ali Aydin, Mustafa Elcioglu, Hanka Venselaar, Anders H. Lund, Richard Bonshek, Graeme C. Black, Forbes D. Manson
Hum Mol Genet. 2015 Dec 1; 24(23): 6565–6579. Published online 2015 Sep 22. doi: 10.1093/hmg/ddv345
PMCID:
PMC4634368
AbstractArticlePDF–1.0M
13.
Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups
Catherine E Bond, Mark L Bettington, Sally-Ann Pearson, Diane M McKeone, Barbara A Leggett, Vicki LJ Whitehall
BMC Cancer. 2015; 15: 20. Published online 2015 Jan 23. doi: 10.1186/s12885-015-1011-9
PMCID:
PMC4318154
AbstractArticlePDF–937K
14.
Methylation of PRDM2, PRDM5 and PRDM16 genes in lung cancer cells
Shuang-Xiang Tan, Rui-Cheng Hu, Jing-Jing Liu, Yong-Li Tan, Wen-En Liu
Int J Clin Exp Pathol. 2014; 7(5): 2305–2311. Published online 2014 Apr 15.
PMCID:
PMC4069964
AbstractArticlePDF–1.1M
15.
Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population
Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte
PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954
PMCID:
PMC3522587
AbstractArticlePDF–130K
16.
The Epigenetic Modifier PRDM5 Functions as a Tumor Suppressor through Modulating WNT/β-Catenin Signaling and Is Frequently Silenced in Multiple Tumors
Xing-sheng Shu, Hua Geng, Lili Li, Jianming Ying, Chunhong Ma, Yajun Wang, Fan Fong Poon, Xian Wang, Ying Ying, Winnie Yeo, Gopesh Srivastava, Sai Wah Tsao, Jun Yu, Joseph J. Y. Sung, Shi Huang, Anthony T. C. Chan, Qian Tao
PLoS One. 2011; 6(11): e27346. Published online 2011 Nov 8. doi: 10.1371/journal.pone.0027346
PMCID:
PMC3210799
AbstractArticlePDF–1.1M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Mutations in PRDM5 in Brittle Cornea Syndrome Identify a Pathway Regulating Extracellular Matrix Development and Maintenance
Emma M.M. Burkitt Wright, Helen L. Spencer, Sarah B. Daly, Forbes D.C. Manson, Leo A.H. Zeef, Jill Urquhart, Nicoletta Zoppi, Richard Bonshek, Ioannis Tosounidis, Meyyammai Mohan, Colm Madden, Annabel Dodds, Kate E. Chandler, Siddharth Banka, Leon Au, Jill Clayton-Smith, Naz Khan, Leslie G. Biesecker, Meredith Wilson, Marianne Rohrbach, Marina Colombi, Cecilia Giunta, Graeme C.M. Black
Am J Hum Genet. 2011 Jun 10; 88(6): 767–777. doi: 10.1016/j.ajhg.2011.05.007
Correction in:
Am J Hum Genet. 2011 Aug 12; 89(2): 346.
PMCID:
PMC3113239
AbstractArticlePDF–1.1M
19.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
20.
A systematic gene-based screen of chr4q22–q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts
Gursharan Kalsi, Po-Hsiu Kuo, Fazil Aliev, Jeffry Alexander, Omari McMichael, Diana G. Patterson, Dermot Walsh, Zhongming Zhao, Marc Schuckit, John Nurnberger, Jr, Howard Edenberg, John Kramer, Vladimir Vladimirov, Carol A. Prescott, Danielle M. Dick, Kenneth S. Kendler, Brien P. Riley
Hum Mol Genet. 2010 Jun 15; 19(12): 2497–2506. Published online 2010 Mar 23. doi: 10.1093/hmg/ddq112
Correction in:
Hum Mol Genet. 2010 Oct 15; 19(20): 4121.
PMCID:
PMC2876884
AbstractArticlePDF–226K

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