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Items: 1 to 20 of 65

1.
Enhanced MAPK signaling induced by CSF3R mutants confers dependence to DUSP1 for leukemic transformation
Meenu Kesarwani, Zachary Kincaid, Mohammad Azhar, Mohammad Azam
Blood Adv. 2024 Jun 11; 8(11): 2765–2776. Published online 2024 Mar 28. doi: 10.1182/bloodadvances.2023010830
PMCID:
PMC11176961
AbstractArticlePDF–2.0M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The RNA m6A demethylase ALKBH5 drives emergency granulopoiesis and neutrophil mobilization by upregulating G-CSFR expression
Yang Liu, Renjie Song, Zhike Lu, Lu Zhao, Xinyi Zhan, Yini Li, Xuetao Cao
Cell Mol Immunol. 2024 Jan; 21(1): 6–18. Published online 2023 Dec 20. doi: 10.1038/s41423-023-01115-9
PMCID:
PMC10757716
AbstractArticlePDF–5.3M
4.
A neutrophil response linked to tumor control in immunotherapy
Jeremy Gungabeesoon, Nicolas A. Gort-Freitas, Máté Kiss, Evangelia Bolli, Marius Messemaker, Marie Siwicki, Mehdi Hicham, Ruben Bill, Peter Koch, Chiara Cianciaruso, Florent Duval, Christina Pfirschke, Michael Mazzola, Solange Peters, Krisztian Homicsko, Christopher Garris, Ralph Weissleder, Allon M. Klein, Mikael J. Pittet
Cell. Author manuscript; available in PMC 2024 Mar 30.
Published in final edited form as: Cell. 2023 Mar 30; 186(7): 1448–1464.e20. doi: 10.1016/j.cell.2023.02.032
PMCID:
PMC10132778
AbstractArticlePDF–2.7M
5.
G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease
Ming-Chin Lee, James A. McCubbin, Anne D. Christensen, Daniel P. Poole, Pradeep Rajasekhar, TinaMarie Lieu, Nigel W. Bunnett, Sonia Garcia-Caraballo, Andelain Erickson, Stuart M. Brierley, Reem Saleh, Adrian Achuthan, Andrew J. Fleetwood, Robin L. Anderson, John A. Hamilton, Andrew D. Cook
J Immunol. Author manuscript; available in PMC 2023 Apr 3.
Published in final edited form as: J Immunol. 2017 May 1; 198(9): 3565–3575. Published online 2017 Mar 20. doi: 10.4049/jimmunol.1602127
PMCID:
PMC10069442
AbstractArticlePDF–2.0M
6.
Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages
Aleksandar Murgaski, Máté Kiss, Helena Van Damme, Daliya Kancheva, Isaure Vanmeerbeek, Jiri Keirsse, Eva Hadadi, Jan Brughmans, Sana M. Arnouk, Ahmed E.I. Hamouda, Ayla Debraekeleer, Victor Bosteels, Yvon Elkrim, Louis Boon, Sabine Hoves, Niels Vandamme, Sofie Deschoemaeker, Sophie Janssens, Abhishek D. Garg, Greetje Vande Velde, Martina Schmittnaegel, Carola H. Ries, Damya Laoui
Cancer Res. 2022 Oct 17; 82(20): 3785–3801. Published online 2022 Aug 18. doi: 10.1158/0008-5472.CAN-22-0094
PMCID:
PMC9574379
AbstractArticlePDF–2.1M
7.
Effect of the unfolded protein response and oxidative stress on mutagenesis in CSF3R: a model for evolution of severe congenital neutropenia to myelodysplastic syndrome/acute myeloid leukemia
Adya Sapra, Roman Jaksik, Hrishikesh Mehta, Sara Biesiadny, Marek Kimmel, Seth J Corey
Mutagenesis. 2020 Sep; 35(5): 381–389. Published online 2021 Jan 29. doi: 10.1093/mutage/geaa027
PMCID:
PMC7846132
AbstractArticlePDF–1.1M
8.
β-Catenin–TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation
Petr Danek, Miroslava Kardosova, Lucie Janeckova, Elena Karkoulia, Karolina Vanickova, Matej Fabisik, Carlos Lozano-Asencio, Touati Benoukraf, Roberto Tirado-Magallanes, Qiling Zhou, Monika Burocziova, Sarka Rahmatova, Robert Pytlik, Tomas Brdicka, Daniel G. Tenen, Vladimir Korinek, Meritxell Alberich-Jorda
Blood. 2020 Nov 26; 136(22): 2574–2587. Prepublished online 2020 Aug 21. doi: 10.1182/blood.2019004664
PMCID:
PMC7714095
AbstractArticle
9.
Bacterial Lipopolysaccharides Suppress Erythroblastic Islands and Erythropoiesis in the Bone Marrow in an Extrinsic and G- CSF-, IL-1-, and TNF-Independent Manner
Kavita Bisht, Joshua Tay, Rebecca N. Wellburn, Crystal McGirr, Whitney Fleming, Bianca Nowlan, Valerie Barbier, Ingrid G. Winkler, Jean-Pierre Levesque
Front Immunol. 2020; 11: 583550. Published online 2020 Oct 6. doi: 10.3389/fimmu.2020.583550
PMCID:
PMC7573160
AbstractArticlePDF–6.6M
10.
G-CSF and G-CSFR Modulate CD4 and CD8 T Cell Responses to Promote Colon Tumor Growth and Are Potential Therapeutic Targets
Ioannis Karagiannidis, Stephanie J. Jerman, Damian Jacenik, Brandon B. Phinney, Ruoxin Yao, Eric R. Prossnitz, Ellen J. Beswick
Front Immunol. 2020; 11: 1885. Published online 2020 Sep 15. doi: 10.3389/fimmu.2020.01885
PMCID:
PMC7522314
AbstractArticlePDF–1.9M
11.
Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils
Karim Mahiddine, Adam Blaisdell, Stephany Ma, Amandine Créquer-Grandhomme, Clifford A. Lowell, Adrian Erlebacher
J Clin Invest. 2020 Jan 2; 130(1): 389–403. Published online 2019 Dec 3. doi: 10.1172/JCI130952
PMCID:
PMC6934192
AbstractArticlePDF–11M
12.
Muscle‐secreted granulocyte colony‐stimulating factor functions as metabolic niche factor ameliorating loss of muscle stem cells in aged mice
Hu Li, Qian Chen, Changyin Li, Ran Zhong, Yixia Zhao, Qianying Zhang, Weimin Tong, Dahai Zhu, Yong Zhang
EMBO J. 2019 Dec 16; 38(24): e102154. Published online 2019 Nov 18. doi: 10.15252/embj.2019102154
PMCID:
PMC6912059
AbstractArticlePDF–3.2M
13.
Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia
Theodore P. Braun, Mariam Okhovat, Cody Coblentz, Sarah A. Carratt, Amy Foley, Zachary Schonrock, Brittany M. Curtiss, Kimberly Nevonen, Brett Davis, Brianna Garcia, Dorian LaTocha, Benjamin R. Weeder, Michal R. Grzadkowski, Joey C. Estabrook, Hannah G. Manning, Kevin Watanabe-Smith, Sophia Jeng, Jenny L. Smith, Amanda R. Leonti, Rhonda E. Ries, Shannon McWeeney, Cristina Di Genua, Roy Drissen, Claus Nerlov, Soheil Meshinchi, Lucia Carbone, Brian J. Druker, Julia E. Maxson
Nat Commun. 2019; 10: 5455. Published online 2019 Nov 29. doi: 10.1038/s41467-019-13364-2
Correction in:
Nat Commun. 2022; 13: 3471.
PMCID:
PMC6884457
AbstractArticlePDF–3.2M
14.
Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors
Andrea Ponzetta, Roberta Carriero, Silvia Carnevale, Marialuisa Barbagallo, Martina Molgora, Chiara Perucchini, Elena Magrini, Francesca Gianni, Paolo Kunderfranco, Nadia Polentarutti, Fabio Pasqualini, Sabrina Di Marco, Domenico Supino, Clelia Peano, Ferdinando Cananzi, Piergiuseppe Colombo, Silvana Pilotti, Suliman Yousef Alomar, Eduardo Bonavita, Maria Rosaria Galdiero, Cecilia Garlanda, Alberto Mantovani, Sebastien Jaillon
Cell. 2019 Jul 11; 178(2): 346–360.e24. doi: 10.1016/j.cell.2019.05.047
PMCID:
PMC6630709
AbstractArticle
15.
Clostridium perfringens α-toxin impairs granulocyte colony-stimulating factor receptor-mediated granulocyte production while triggering septic shock
Masaya Takehara, Soshi Seike, Yuuta Sonobe, Hiroto Bandou, Saki Yokoyama, Teruhisa Takagishi, Kazuaki Miyamoto, Keiko Kobayashi, Masahiro Nagahama
Commun Biol. 2019; 2: 45. Published online 2019 Jan 31. doi: 10.1038/s42003-019-0280-2
PMCID:
PMC6355902
AbstractArticlePDF–5.4M
16.
Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes
Jennifer Kurz, Julia Barthelmes, Leonard Blum, Thomas Ulshöfer, Marthe-Susanna Wegner, Nerea Ferreirós, Luise Roser, Gerd Geisslinger, Sabine Grösch, Susanne Schiffmann
Sci Rep. 2019; 9: 747. Published online 2019 Jan 24. doi: 10.1038/s41598-018-37342-8
PMCID:
PMC6345911
AbstractArticlePDF–1.9M
17.
Myeloid-Specific Deletion of Mcl-1 Yields Severely Neutropenic Mice That Survive and Breed in Homozygous Form
Janka Zsófia Csepregi, Anita Orosz, Erik Zajta, Orsolya Kása, Tamás Németh, Edina Simon, Szabina Fodor, Katalin Csonka, Balázs L. Barátki, Dorottya Kövesdi, You-Wen He, Attila Gácser, Attila Mócsai
J Immunol. 2018 Dec 15; 201(12): 3793–3803. Published online 2018 Nov 21. doi: 10.4049/jimmunol.1701803
PMCID:
PMC6287103
AbstractArticlePDF–1.7M
18.
Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus
Ramya Sivakumar, Georges Abboud, Clayton E. Mathews, Mark A. Atkinson, Laurence Morel
Front Immunol. 2018; 9: 1053. Published online 2018 May 9. doi: 10.3389/fimmu.2018.01053
PMCID:
PMC5954343
AbstractArticlePDF–7.2M
19.
Bone marrow drives central nervous system regeneration after radiation injury
Jorg Dietrich, Ninib Baryawno, Naema Nayyar, Yannis K. Valtis, Betty Yang, Ina Ly, Antoine Besnard, Nicolas Severe, Karin U. Gustafsson, Ovidiu C. Andronesi, Tracy T. Batchelor, Amar Sahay, David T. Scadden
J Clin Invest. 2018 Jan 2; 128(1): 281–293. Published online 2017 Dec 4. doi: 10.1172/JCI90647
Correction in:
J Clin Invest. 2018 Jun 1; 128(6): 2651.
PMCID:
PMC5749546
AbstractArticlePDF–18M
20.
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease
Eunsil Hahm, Changli Wei, Isabel Fernandez, Jing Li, Nicholas J Tardi, Melissa Tracy, Shikha Wadhwani, Yanxia Cao, Vasil Peev, Andrew Zloza, Jevgenijs Lusciks, Salim S Hayek, Christopher O’Connor, Markus Bitzer, Vineet Gupta, Sanja Sever, David B Sykes, David T Scadden, Jochen Reiser
Nat Med. Author manuscript; available in PMC 2017 Jul 1.
Published in final edited form as: Nat Med. 2017 Jan; 23(1): 100–106. Published online 2016 Dec 12. doi: 10.1038/nm.4242
PMCID:
PMC5405698
AbstractArticlePDF–745K

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