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Select item 110707081.

Stimulating intestinal GIP release reduces food intake and body weight in mice

Jo E. Lewis, Danae Nuzzaci, Paula-Peace James-Okoro, Mireia Montaner, Elisabeth O'Flaherty, Tamana Darwish, Marito Hayashi, Stephen D. Liberles, David Hornigold, Jacqueline Naylor, David Baker, Fiona M. Gribble, Frank Reimann

Mol Metab. 2024 Jun; 84: 101945. Published online 2024 Apr 21. doi: 10.1016/j.molmet.2024.101945

PMCID:: PMC11070708

Abstract Article PDF–3.0M

Select item 102530022.

TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine

Valeriya V. Zinina, Melanie Sauer, Lira Nigmatullina, Nastasja Kreim, Natalia Soshnikova

Cells. 2023 Jun; 12(11): 1452. Published online 2023 May 23. doi: 10.3390/cells12111452

PMCID:: PMC10253002

Abstract Article PDF–2.4M

Select item 93264913.

Noninvasive Evaluation of GIP Effects on β-Cell Mass Under High-Fat Diet

Sakura Kiyobayashi, Takaaki Murakami, Norio Harada, Hiroyuki Fujimoto, Yuki Murata, Naotaka Fujita, Keita Hamamatsu, Eri Ikeguchi-Ogura, Tomonobu Hatoko, Xuejing Lu, Shunsuke Yamane, Nobuya Inagaki

Front Endocrinol (Lausanne) 2022; 13: 921125. Published online 2022 Jul 12. doi: 10.3389/fendo.2022.921125

PMCID:: PMC9326491

Abstract Article PDF–2.7M

Select item 83829974.

Medium-chain triglycerides inhibit long-chain triglyceride-induced GIP secretion through GPR120-dependent inhibition of CCK

Yuki Murata, Norio Harada, Shigenobu Kishino, Kanako Iwasaki, Eri Ikeguchi-Ogura, Shunsuke Yamane, Tomoko Kato, Yoshinori Kanemaru, Akiko Sankoda, Tomonobu Hatoko, Sakura Kiyobayashi, Jun Ogawa, Akira Hirasawa, Nobuya Inagaki

iScience. 2021 Sep 24; 24(9): 102963. Published online 2021 Aug 9. doi: 10.1016/j.isci.2021.102963

PMCID:: PMC8382997

Abstract Article PDF–3.1M

Select item 79587145.

A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

Kristoffer L. Egerod, Maja S. Engelstoft, Kaare V. Grunddal, Mark K. Nøhr, Anna Secher, Ichiro Sakata, Jens Pedersen, Johanne A. Windeløv, Ernst-Martin Füchtbauer, Jørgen Olsen, Frank Sundler, Jan P. Christensen, Nils Wierup, Jesper V. Olsen, Jens J. Holst, Jeffrey M. Zigman, Steen S. Poulsen, Thue W. Schwartz

Endocrinology. 2012 Dec 1; 153(12): 5782–5795. Published online 2012 Dec 1. doi: 10.1210/en.2012-1595

PMCID:: PMC7958714

Abstract Article

Select item 78832166.

Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice; Extremely rapid degradation but marked variation between available assays

Geke Aline Boer, Bolette Hartmann, Jens Juul Holst

Peptides. 2021 Feb; 136: 170457. doi: 10.1016/j.peptides.2020.170457

PMCID:: PMC7883216

Abstract Article

Select item 76857567.

Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes

Okechi S. Oduori, Naoya Murao, Kenju Shimomura, Harumi Takahashi, Quan Zhang, Haiqiang Dou, Shihomi Sakai, Kohtaro Minami, Belen Chanclon, Claudia Guida, Lakshmi Kothegala, Johan Tolö, Yuko Maejima, Norihide Yokoi, Yasuhiro Minami, Takashi Miki, Patrik Rorsman, Susumu Seino

J Clin Invest. 2020 Dec 1; 130(12): 6639–6655. Published online 2020 Nov 16. doi: 10.1172/JCI140046

PMCID:: PMC7685756

Abstract Article PDF–6.7M

Select item 70404588.

Absence of GIP secretion alleviates age-related obesity and insulin resistance

Yoshinori Kanemaru, Norio Harada, Satoko Shimazu-Kuwahara, Shunsuke Yamane, Eri Ikeguchi, Yuki Murata, Sakura Kiyobayashi, Tomonobu Hatoko, Nobuya Inagaki

J Endocrinol. 2020 Apr; 245(1): 13–20. Published online 2020 Jan 23. doi: 10.1530/JOE-19-0477

PMCID:: PMC7040458

Abstract Article PDF–1.1M

Select item 67696709.

Diet-Induced Obese Mice and Leptin-Deficient Lep^ob/ob Mice Exhibit Increased Circulating GIP Levels Produced by Different Mechanisms

Eunyoung Lee, Emily L. Miedzybrodzka, Xilin Zhang, Ryo Hatano, Junki Miyamoto, Ikuo Kimura, Kosuke Fujimoto, Satoshi Uematsu, Sergio Rodriguez-Cuenca, Antonio Vidal-Puig, Fiona M. Gribble, Frank Reimann, Takashi Miki

Int J Mol Sci. 2019 Sep; 20(18): 4448. Published online 2019 Sep 10. doi: 10.3390/ijms20184448

PMCID:: PMC6769670

Abstract Article PDF–3.5M

Select item 672876610.

Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

Julie Piccand, Constance Vagne, Florence Blot, Aline Meunier, Anthony Beucher, Perrine Strasser, Mari L. Lund, Sabitri Ghimire, Laure Nivlet, Céline Lapp, Natalia Petersen, Maja S. Engelstoft, Christelle Thibault-Carpentier, Céline Keime, Sara Jimenez Correa, Valérie Schreiber, Nacho Molina, Thue W. Schwartz, Adèle De Arcangelis, Gérard Gradwohl

Mol Metab. 2019 Nov; 29: 24–39. Published online 2019 Aug 13. doi: 10.1016/j.molmet.2019.08.007

PMCID:: PMC6728766

Abstract Article PDF–3.3M

Select item 641454811.

HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide

Romain Girard, Mathieu Darsigny, Christine Jones, Faïza Maloum-Rami, Yves Gélinas, André C. Carpentier, Mathieu Laplante, Nathalie Perreault, François Boudreau

Sci Rep. 2019; 9: 4200. Published online 2019 Mar 12. doi: 10.1038/s41598-019-41061-z

PMCID:: PMC6414548

Abstract Article PDF–5.7M

Select item 541478912.

RNA-Seq Analysis of Enteroendocrine Cells Reveals a Role for FABP5 in the Control of GIP Secretion

Cesar A. Sommer, Gustavo Mostoslavsky

Mol Endocrinol. 2014 Nov; 28(11): 1855–1865. Published online 2014 Sep 30. doi: 10.1210/me.2014-1194

PMCID:: PMC5414789

Abstract Article

Select item 516124313.

Downregulation of a GPCR by β-Arrestin2-mediated Switch from an Endosomal to a TGN Recycling Pathway

Nazish Abdullah, Muheeb Beg, David Soares, Jeremy S. Dittman, Timothy E McGraw

Cell Rep. Author manuscript; available in PMC 2017 Dec 13.

Published in final edited form as: Cell Rep. 2016 Dec 13; 17(11): 2966–2978. doi: 10.1016/j.celrep.2016.11.050

PMCID:: PMC5161243

Abstract Article PDF–2.0M

Select item 476109314.

Galanin inhibits GLP‐1 and GIP secretion via the GAL₁ receptor in enteroendocrine L and K cells

Arianna Psichas, Leslie L Glass, Stephen J Sharp, Frank Reimann, Fiona M Gribble

Br J Pharmacol. 2016 Mar; 173(5): 888–898. Published online 2016 Feb 8. doi: 10.1111/bph.13407

PMCID:: PMC4761093

Abstract Article PDF–1.2M

Select item 456172915.

Islet Cells Serve as Cells of Origin of Pancreatic Gastrin-Positive Endocrine Tumors

Rémy Bonnavion, Romain Teinturier, Rami Jaafar, Doriane Ripoche, Emmanuelle Leteurtre, Yuan-Jia Chen, Jens F. Rehfeld, Florian Lepinasse, Valérie Hervieu, François Pattou, Marie-Christine Vantyghem, Jean-Yves Scoazec, Philippe Bertolino, Chang Xian Zhang

Mol Cell Biol. 2015 Oct; 35(19): 3274–3283. Prepublished online 2015 Jul 13. Published online 2015 Sep 4. doi: 10.1128/MCB.00302-15