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Select item 111165281.

A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila

Alka Singh, Kandahalli Venkataranganayaka Abhilasha, Kathya R. Acharya, Haibo Liu, Niraj K. Nirala, Velayoudame Parthibane, Govind Kunduri, Thiruvaimozhi Abimannan, Jacob Tantalla, Lihua Julie Zhu, Jairaj K. Acharya, Usha R. Acharya

Nat Commun. 2024; 15: 4410. Published online 2024 May 23. doi: 10.1038/s41467-024-48851-8

PMCID:: PMC11116528

Abstract Article PDF–8.0M

Select item 111146452.

Identified peptidergic neurons in the Drosophila brain regulate insulin-producing cells, stress responses and metabolism by coexpressed short neuropeptide F and corazonin

Neval Kapan, Oleh V. Lushchak, Jiangnan Luo, Dick R. Nässel

Cell Mol Life Sci. 2012 Dec; 69(23): 4051–4066. Published online 2012 Jul 25. doi: 10.1007/s00018-012-1097-z

PMCID:: PMC11114645

Abstract Article PDF–2.3M

Select item 111133943.

Food odors trigger an endocrine response that affects food ingestion and metabolism

Oleh V. Lushchak, Mikael A. Carlsson, Dick R. Nässel

Cell Mol Life Sci. 2015 Aug; 72(16): 3143–3155. Published online 2015 Mar 18. doi: 10.1007/s00018-015-1884-4

PMCID:: PMC11113394

Abstract Article PDF–1.6M

Select item 111084704.

Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Dick R. Nässel, Jozef Vanden Broeck

Cell Mol Life Sci. 2016 Jan; 73(2): 271–290. Published online 2015 Oct 15. doi: 10.1007/s00018-015-2063-3

PMCID:: PMC11108470

Abstract Article PDF–1.3M

Select item 110607185.

Conditional chemoconnectomics (cCCTomics) as a strategy for efficient and conditional targeting of chemical transmission

Renbo Mao, Jianjun Yu, Bowen Deng, Xihuimin Dai, Yuyao Du, Sujie Du, Wenxia Zhang, Yi Rao

eLife. 2024; 12: RP91927. Published online 2024 Apr 30. doi: 10.7554/eLife.91927

PMCID:: PMC11060718

Abstract Article PDF–4.3M

Select item 110242956.

The diverse roles of insulin signaling in insect behavior

Anastasia A. Weger, Clare C. Rittschof

Front Insect Sci. 2024; 4: 1360320. Published online 2024 Apr 4. doi: 10.3389/finsc.2024.1360320

PMCID:: PMC11024295

Abstract Article PDF–667K

Select item 109455087.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 108568098.

Betulinic Acid Increases the Lifespan of Drosophila melanogaster via Sir2 and FoxO Activation

Hye-Yeon Lee, Kyung-Jin Min

Nutrients. 2024 Feb; 16(3): 441. Published online 2024 Feb 1. doi: 10.3390/nu16030441

PMCID:: PMC10856809

Abstract Article PDF–2.3M

Select item 108350479.

miR-137 regulates PTP61F, affecting insulin signaling, metabolic homeostasis, and starvation resistance in Drosophila

Hana Saedi, Girma Waro, Lea Giacchetta, Susan Tsunoda

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2319475121. Published online 2024 Jan 22. doi: 10.1073/pnas.2319475121

PMCID:: PMC10835047

Abstract Article PDF–3.0M

Select item 1067176710.

Yeast Hydrolysate Inhibits Lipid Accumulation via Regulation of Lipid Accumulation-Related Genes in a Drosophila Model of High-Sugar Diet-Induced Obesity

Nari Kim, Yejin Ahn, Kayoung Ko, Boyun Kim, Kisoo Han, Hyung Joo Suh, Jewon Jung, Ki-Bae Hong

Int J Mol Sci. 2023 Nov; 24(22): 16302. Published online 2023 Nov 14. doi: 10.3390/ijms242216302

PMCID:: PMC10671767

Abstract Article PDF–2.7M

Select item 1066833611.

Early-life hypoxia alters adult physiology and reduces stress resistance and lifespan in Drosophila

Danielle M. Polan, Mohammed Alansari, Byoungchun Lee, Savraj S. Grewal

J Exp Biol. 2020 Nov 15; 223(22): jeb226027. Published online 2020 Nov 23. doi: 10.1242/jeb.226027

PMCID:: PMC10668336

Abstract Article

Select item 1065646112.

A low-sugar diet enhances Drosophila body size in males and females via sex-specific mechanisms

Jason W. Millington, Puja Biswas, Charlotte Chao, Yi Han Xia, Lianna W. Wat, George P. Brownrigg, Ziwei Sun, Paige J. Basner-Collins, Ramon I. Klein Geltink, Elizabeth J. Rideout

Development. 2022 Mar 15; 149(6): dev200491. Published online 2022 Mar 28. doi: 10.1242/dev.200491

PMCID:: PMC10656461

Abstract Article

Select item 1062962013.

Diet-induced glial insulin resistance impairs the clearance of neuronal debris in Drosophila brain

Mroj Alassaf, Akhila Rajan

PLoS Biol. 2023 Nov; 21(11): e3002359. Published online 2023 Nov 7. doi: 10.1371/journal.pbio.3002359

PMCID:: PMC10629620

Abstract Article PDF–3.4M

Select item 1061853214.

Isolation of Enterococcus faecium and determination of its mechanism for promoting the growth and development of Drosophila

Yujuan Li, Lei Pan, Pengcheng Li, Fuguo Gao, Lei Wang, Jian Chen, Zhichao Li, Yongheng Gao, Yumei Gong, Faguang Jin

Sci Rep. 2023; 13: 18726. Published online 2023 Oct 31. doi: 10.1038/s41598-023-43727-1

PMCID:: PMC10618532

Abstract Article PDF–3.2M

Select item 1056021715.

Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans

Cristina M. Viola, Orsolya Frittmann, Huw T. Jenkins, Talha Shafi, Pierre De Meyts, Andrzej M. Brzozowski

Nat Commun. 2023; 14: 6271. Published online 2023 Oct 7. doi: 10.1038/s41467-023-41862-x

PMCID:: PMC10560217

Abstract Article PDF–2.9M

Select item 1055820516.

Exposure to high-sugar diet induces transgenerational changes in sweet sensitivity and feeding behavior via H3K27me3 reprogramming

Jie Yang, Ruijun Tang, Shiye Chen, Yinan Chen, Kai Yuan, Rui Huang, Liming Wang

eLife. 2023; 12: e85365. Published online 2023 Sep 12. doi: 10.7554/eLife.85365

PMCID:: PMC10558205

Abstract Article PDF–2.4M

Select item 1046377617.

Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity

Javier Morón-Oset, Lilly Katharina Sophie Fischer, Nathalie Jauré, Pingze Zhang, Annika Julia Jahn, Tessa Supèr, André Pahl, Adrian M. Isaacs, Sebastian Grönke, Linda Partridge

Acta Neuropathol Commun. 2023; 11: 140. Published online 2023 Aug 29. doi: 10.1186/s40478-023-01634-6