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Select item 112379301.

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein

Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo

J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390

PMCID:: PMC11237930

Abstract Article PDF–3.8M

Select item 107890522.

ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans

Hongyu Luo, Linjiang Lao, Kit Sing Au, Hope Northrup, Xiao He, Diane Forget, Marie-Soleil Gauthier, Benoit Coulombe, Isabelle Bourdeau, Wei Shi, Lucia Gagliardi, Maria Candida Barisson Villares Fragoso, Junzheng Peng, Jiangping Wu

Genome Biol. 2024; 25: 19. Published online 2024 Jan 15. doi: 10.1186/s13059-023-03147-w

PMCID:: PMC10789052

Abstract Article PDF–4.3M

Select item 105220723.

ARMC5 mutations are associated with high levels of proliferating cell nuclear antigen and the presence of the serotonin receptor 5HT4R in PMAH nodules

Barbara Brito da Conceição, Isadora Pontes Cavalcante, Jean Lucas Kremer, Thais Barabba Auricino, Eduarda Corrêa Bento, Maria Claudia Nogueira Zerbini, Maria Candida Barisson Villares Fragoso, Claudimara Ferini Pacicco Lotfi

Arch Endocrinol Metab. 2020 Jul-Aug; 64(4): 390–401. Published online 2020 Mar 30. doi: 10.20945/2359-3997000000236

PMCID:: PMC10522072

Abstract Article PDF–10M

Select item 100940834.

New pathogenic variants in ARMC5 gene in a series of Italian patients affected by primary bilateral macronodular adrenocortical hyperplasia (PBMAH)

Mara Giacché, Alessandra Panarotto, Luigi Mori, Pietro Luigi Poliani, Roberto Lanzi, Marco Schiavo Lena, Maurizio Castellano

Mol Genet Genomic Med. 2023 Apr; 11(4): e2126. Published online 2023 Feb 2. doi: 10.1002/mgg3.2126

PMCID:: PMC10094083

Abstract Article PDF–935K

Select item 92621535.

ARMC5 variants in PRKAR1A mutated patients modify cortisol levels and Cushing syndrome

Andrea Gutierrez Maria, Christina Tatsi, Annabel Berthon, Ludivine Drougat, Nikolaos Settas, Fady Hannah-Shmouni, Jerome Bertherat, Fabio R. Faucz, Constantine A. Stratakis

Endocr Relat Cancer. Author manuscript; available in PMC 2022 Jul 7.

Published in final edited form as: Endocr Relat Cancer. 2020 Sep; 27(9): 509–517. doi: 10.1530/ERC-20-0273

PMCID:: PMC9262153

Abstract Article PDF–795K

Select item 92265106.

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia

Linjiang Lao, Isabelle Bourdeau, Lucia Gagliardi, Xiao He, Wei Shi, Bingbing Hao, Minjia Tan, Yan Hu, Junzheng Peng, Benoit Coulombe, David J Torpy, Hamish S Scott, Andre Lacroix, Hongyu Luo, Jiangping Wu

Nucleic Acids Res. 2022 Jun 24; 50(11): 6343–6367. Published online 2022 Jun 10. doi: 10.1093/nar/gkac483

PMCID:: PMC9226510

Abstract Article PDF–3.7M

Select item 91052357.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 88970228.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 83529649.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 827460310.

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome

Jérémy A. Ferreira Barbosa, Samantha Sparapani, Jonathan Boulais, Robert Lodge, Éric A. Cohen

J Virol. 2021 Aug; 95(15): e00971-20. Prepublished online 2021 May 19. Published online 2021 Jul 12. doi: 10.1128/JVI.00971-20

PMCID:: PMC8274603

Abstract Article PDF–4.2M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 795717612.

Deubiquitylation and stabilization of ARMC5 by ubiquitin‐specific processing protease 7 (USP7) are critical for RCC proliferation

Guobei Yan, Na Liu, Jun Tian, Yanli Fu, Wei Wei, Jingjing Zou, Suping Li, Qing Wang, Kai Li, Junhua Wang

J Cell Mol Med. 2021 Mar; 25(6): 3149–3159. Published online 2021 Feb 5. doi: 10.1111/jcmm.16306

PMCID:: PMC7957176

Abstract Article PDF–1.4M

Select item 756688113.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 754784114.

ARMC5 Alterations in Patients With Sporadic Neuroendocrine Tumors and Multiple Endocrine Neoplasia Type 1 (MEN1)

Svetozar S Damjanovic, Jadranka A Antic, Valentina I Elezovic-Kovacevic, Dusko M Dundjerovic, Ivana T Milicevic, Bojana B Beleslin-Cokic, Bojana B Ilic, Gordana S Rodic, Annabel Berthon, Andrea Gutierrez Maria, Fabio R Faucz, Constantine A Stratakis

J Clin Endocrinol Metab. 2020 Dec; 105(12): e4531–e4542. Published online 2020 Sep 8. doi: 10.1210/clinem/dgaa631

PMCID:: PMC7547841

Abstract Article

Select item 732206715.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 730807716.

The Association of ARMC5 with the Renin-Angiotensin-Aldosterone System, Blood Pressure, and Glycemia in African Americans

Joshua J Joseph, Xiaofei Zhou, Mihail Zilbermint, Constantine A Stratakis, Fabio R Faucz, Maya B Lodish, Annabel Berthon, James G Wilson, Willa A Hsueh, Sherita H Golden, Shili Lin

J Clin Endocrinol Metab. 2020 Aug; 105(8): 2625–2633. Published online 2020 May 21. doi: 10.1210/clinem/dgaa290

PMCID:: PMC7308077

Abstract Article

Select item 716998317.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 701910018.

Allelic Variants of ARMC5 in Patients With Adrenal Incidentalomas and in Patients With Cushing's Syndrome Associated With Bilateral Adrenal Nodules

Beatriz Marinho de Paula Mariani, Mirian Yumie Nishi, Ingrid Quevedo Wanichi, Vania Balderrama Brondani, Amanda Meneses Ferreira Lacombe, Helaine Charchar, Maria Adelaide Albergaria Pereira, Victor Srougi, Fabio Yoshiaki Tanno, Filippo Ceccato, Daniela Regazzo, Mattia Barbot, Gianluca Occhi, Nora Maria Elvira Albiger, Marcelo Vieira-Corrêa, Claudio Elias Kater, Carla Scaroni, José Luis Chambô, Maria Claudia Nogueira Zerbini, Berenice B. Mendonca, Madson Q. Almeida, Maria Candida Barisson Villares Fragoso

Front Endocrinol (Lausanne) 2020; 11: 36. Published online 2020 Feb 7. doi: 10.3389/fendo.2020.00036

PMCID:: PMC7019100

Abstract Article PDF–776K

Select item 666214319.

ARMC5 Variants and Risk of Hypertension in Blacks: MH‐GRID Study

Mihail Zilbermint, Amadou Gaye, Annabel Berthon, Fady Hannah‐Shmouni, Fabio R. Faucz, Maya B. Lodish, Adam R. Davis, Gary H. Gibbons, Constantine A. Stratakis

J Am Heart Assoc. 2019 Jul 16; 8(14): e012508. Published online 2019 Jul 3. doi: 10.1161/JAHA.119.012508

PMCID:: PMC6662143

Abstract Article PDF–920K

Select item 578493220.

ARMC5 mutations in familial and sporadic primary bilateral macronodular adrenal hyperplasia

Liping Yu, Junqing Zhang, Xiaohui Guo, Xiaoyu Chen, Zhisong He, Qun He

PLoS One. 2018; 13(1): e0191602. Published online 2018 Jan 25. doi: 10.1371/journal.pone.0191602

PMCID:: PMC5784932

Abstract Article PDF–3.2M

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