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Select item 102251231.

Identifying C1QB, ITGAM, and ITGB2 as potential diagnostic candidate genes for diabetic nephropathy using bioinformatics analysis

Yongzheng Hu, Yani Yu, Hui Dong, Wei Jiang

PeerJ. 2023; 11: e15437. Published online 2023 May 25. doi: 10.7717/peerj.15437

PMCID:: PMC10225123

Abstract Article PDF–4.2M

Select item 97979882.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 97053123.

C1QA, C1QB, and GZMB are novel prognostic biomarkers of skin cutaneous melanoma relating tumor microenvironment

Zhuoshuai Liang, Lingfeng Pan, Jikang Shi, Lianbo Zhang

Sci Rep. 2022; 12: 20460. Published online 2022 Nov 28. doi: 10.1038/s41598-022-24353-9

Correction in:: Sci Rep. 2023; 13: 10973.

PMCID:: PMC9705312

Abstract Article PDF–4.9M

Select item 90777304.

Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology

Yuanyuan Jiao, Shimin Jiang, Ying Wang, Tianyu Yu, Guming Zou, Li Zhuo, Wenge Li

J Diabetes Investig. 2022 May; 13(5): 839–849. Published online 2022 Jan 10. doi: 10.1111/jdi.13739

PMCID:: PMC9077730

Abstract Article PDF–1.9M

Select item 81847845.

SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

Clemens Gutmann, Kaloyan Takov, Sean A. Burnap, Bhawana Singh, Hashim Ali, Konstantinos Theofilatos, Ella Reed, Maria Hasman, Adam Nabeebaccus, Matthew Fish, Mark JW. McPhail, Kevin O’Gallagher, Lukas E. Schmidt, Christian Cassel, Marieke Rienks, Xiaoke Yin, Georg Auzinger, Salvatore Napoli, Salma F. Mujib, Francesca Trovato, Barnaby Sanderson, Blair Merrick, Umar Niazi, Mansoor Saqi, Konstantina Dimitrakopoulou, Rafael Fernández-Leiro, Silke Braun, Romy Kronstein-Wiedemann, Katie J. Doores, Jonathan D. Edgeworth, Ajay M. Shah, Stefan R. Bornstein, Torsten Tonn, Adrian C. Hayday, Mauro Giacca, Manu Shankar-Hari, Manuel Mayr

Nat Commun. 2021; 12: 3406. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23494-1

PMCID:: PMC8184784

Abstract Article PDF–7.5M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80787287.

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Alexandra Naba, Oliver M. T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes

J Proteome Res. Author manuscript; available in PMC 2021 Apr 27.

Published in final edited form as: J Proteome Res. 2017 Aug 4; 16(8): 3083–3091. Published online 2017 Jul 19. doi: 10.1021/acs.jproteome.7b00191

PMCID:: PMC8078728

Abstract Article PDF–2.1M

Select item 71699838.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67632429.

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development

Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong

J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107

PMCID:: PMC6763242

Abstract Article PDF–12M

Select item 596639010.

Investigation of C1-complex regions reveals new C1Q variants associated with protection from systemic lupus erythematosus, and affect its transcript abundance

Jianping Guo, Yanyan Gao, Yuxuan Wang, Yundong Zou, Yan Du, Cainan Luo, Yamei Shi, Yue Yang, Xinyu Wu, Yin Su, Lijun Wu, Shi Chen, Zhanguo Li

Sci Rep. 2018; 8: 8048. Published online 2018 May 23. doi: 10.1038/s41598-018-26380-x

PMCID:: PMC5966390

Abstract Article PDF–2.0M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 541264712.

Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression

Myoungsun Son, Betty Diamond, Bruce T. Volpe, Cynthia B. Aranow, Meggan C. Mackay, Frances Santiago-Schwarz

Sci Rep. 2017; 7: 270. Published online 2017 Mar 21. doi: 10.1038/s41598-017-00290-w

PMCID:: PMC5412647

Abstract Article PDF–2.6M

Select item 529307313.

Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

Simon A. Mortensen, Bjoern Sander, Rasmus K. Jensen, Jan Skov Pedersen, Monika M. Golas, Jens C. Jensenius, Annette G. Hansen, Steffen Thiel, Gregers R. Andersen

Proc Natl Acad Sci U S A. 2017 Jan 31; 114(5): 986–991. Published online 2017 Jan 19. doi: 10.1073/pnas.1616998114

PMCID:: PMC5293073

Abstract Article PDF–1.1M

Select item 515340414.

Analysis of the Interaction between Globular Head Modules of Human C1q and Its Candidate Receptor gC1qR

Lina Pednekar, Ansar A. Pathan, Basudev Paudyal, Anthony G. Tsolaki, Anuvinder Kaur, Suhair M. Abozaid, Lubna Kouser, Haseeb A. Khan, Ellinor I. Peerschke, Mohamed H. Shamji, Gudrun Stenbeck, Berhane Ghebrehiwet, Uday Kishore

Front Immunol. 2016; 7: 567. Published online 2016 Dec 13. doi: 10.3389/fimmu.2016.00567

PMCID:: PMC5153404

Abstract Article PDF–2.7M

Select item 489452715.

Fundamental role of C1q in autoimmunity and inflammation

Myoungsun Son, Betty Diamond, Frances Santiago-Schwarz

Immunol Res. Author manuscript; available in PMC 2016 Jun 6.

Published in final edited form as: Immunol Res. 2015 Dec; 63(1-3): 101–106. doi: 10.1007/s12026-015-8705-6

PMCID:: PMC4894527

Abstract Article PDF–235K

Select item 461721116.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043