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Items: 1 to 20 of 324

1.
H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours
Diego Dibitetto, Martin Liptay, Francesca Vivalda, Hülya Dogan, Ewa Gogola, Martín González Fernández, Alexandra Duarte, Jonas A. Schmid, Morgane Decollogny, Paola Francica, Sara Przetocka, Stephen T. Durant, Josep V. Forment, Ismar Klebic, Myriam Siffert, Roebi de Bruijn, Arne N. Kousholt, Nicole A. Marti, Martina Dettwiler, Claus S. Sørensen, Jean-Christophe Tille, Manuela Undurraga, Intidhar Labidi-Galy, Massimo Lopes, Alessandro A. Sartori, Jos Jonkers, Sven Rottenberg
Nat Commun. 2024; 15: 4430. Published online 2024 May 24. doi: 10.1038/s41467-024-48715-1
PMCID:
PMC11126719
AbstractArticlePDF–3.1M
2.
γ-radiation-induced γH2AX formation occurs preferentially in actively transcribing euchromatic loci
Raja S. Vasireddy, Tom C. Karagiannis, Assam El-Osta
Cell Mol Life Sci. 2010 Jan; 67(2): 291–294. Published online 2009 Oct 27. doi: 10.1007/s00018-009-0181-5
PMCID:
PMC11115934
AbstractArticlePDF–265K
3.
Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7
Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord
Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537
PMCID:
PMC10850818
AbstractArticlePDF–2.7M
4.
PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805
Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang
Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558
PMCID:
PMC10240998
AbstractArticlePDF–4.4M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
6.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
7.
Overexpression of tripartite motif-containing 47 (TRIM47) confers sensitivity to PARP inhibition via ubiquitylation of BRCA1 in triple negative breast cancer cells
Fengen Liu, Binhui Xie, Rong Ye, Yuankang Xie, Baiyin Zhong, Jinrong Zhu, Yao Tang, Zelong Lin, Huiru Tang, Ziqing Wu, Heping Li
Oncogenesis. 2023 Dec; 12(1): 13. Published online 2023 Mar 11. doi: 10.1038/s41389-023-00453-7
PMCID:
PMC10008536
AbstractArticlePDF–5.1M
8.
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis
Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang
EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762
PMCID:
PMC9986817
AbstractArticlePDF–3.5M
9.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
10.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
11.
A standardized nomenclature for mammalian histone genes
Ruth L. Seal, Paul Denny, Elspeth A. Bruford, Anna K. Gribkova, David Landsman, William F. Marzluff, Monica McAndrews, Anna R. Panchenko, Alexey K. Shaytan, Paul B. Talbert
Epigenetics Chromatin. 2022; 15: 34. Published online 2022 Oct 1. doi: 10.1186/s13072-022-00467-2
PMCID:
PMC9526256
AbstractArticlePDF–1.1M
12.
PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer
Liliang Shen, Junfeng Zhang, Zongtai Zheng, Fuhan Yang, Shenghua Liu, Yuan Wu, Yifan Chen, Tianyuan Xu, Shiyu Mao, Yang Yan, Wei Li, Wentao Zhang, Xudong Yao
Int J Biol Sci. 2022; 18(14): 5459–5474. Published online 2022 Aug 29. doi: 10.7150/ijbs.74546
PMCID:
PMC9461664
AbstractArticlePDF–3.5M
13.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy
Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui
Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y
PMCID:
PMC9440653
AbstractArticlePDF–2.9M
14.
LncRNA CTBP1-DT-encoded microprotein DDUP sustains DNA damage response signalling to trigger dual DNA repair mechanisms
Ruyuan Yu, Yameng Hu, Shuxia Zhang, Xincheng Li, Miaoling Tang, Meisongzhu Yang, Xingui Wu, Ziwen Li, Xinyi Liao, Yingru Xu, Man Li, Suwen Chen, Wanying Qian, Li-Yun Gong, Libing Song, Jun Li
Nucleic Acids Res. 2022 Aug 12; 50(14): 8060–8079. Published online 2022 Jul 18. doi: 10.1093/nar/gkac611
PMCID:
PMC9371908
AbstractArticlePDF–13M
15.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
16.
SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication
Hainan Liu, Yu Bai, Xun Zhang, Ting Gao, Yue Liu, Entao Li, Xuefeng Wang, Zheng Cao, Lin Zhu, Qincai Dong, Yong Hu, Guangfei Wang, Caiwei Song, Xiayang Niu, Tong Zheng, Di Wang, Zijing Liu, Yanwen Jin, Ping Li, Xiuwu Bian, Cheng Cao, Xuan Liu
J Virol. 2022 Jun; 96(12): e00412-22. Published online 2022 Jun 2. doi: 10.1128/jvi.00412-22
PMCID:
PMC9215227
AbstractArticlePDF–4.2M
17.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
18.
Genetic variations in ATM and H2AX loci contribute to risk of hematological abnormalities in individuals exposed to BTEX chemicals
Samaneh Jafari Roshan, Yaser Mansoori, Seyed Reza Hosseini, Davood Sabour, Abdolreza Daraei
J Clin Lab Anal. 2022 Apr; 36(4): e24321. Published online 2022 Mar 2. doi: 10.1002/jcla.24321
PMCID:
PMC8993635
AbstractArticlePDF–506K
19.
Pyruvate Facilitates FACT‐Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma
Siyang Wu, Ruixiu Cao, Bangbao Tao, Ping Wu, Chao Peng, Hong Gao, Ji Liang, Weiwei Yang
Adv Sci (Weinh) 2022 Mar; 9(8): 2104055. Published online 2022 Jan 20. doi: 10.1002/advs.202104055
PMCID:
PMC8922107
AbstractArticlePDF–12M
20.
TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair
Gurusamy Hariharasudhan, Seo-Yeon Jeong, Min-Ji Kim, Sung Mi Jung, Gwanwoo Seo, Ju-Ran Moon, Sumi Lee, In-Youb Chang, Younghoon Kee, Ho Jin You, Jung-Hee Lee
Nucleic Acids Res. 2022 Feb 22; 50(3): 1501–1516. Published online 2022 Jan 21. doi: 10.1093/nar/gkac009
PMCID:
PMC8860612
AbstractArticlePDF–4.5M

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