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Items: 1 to 20 of 56

1.
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer
Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740
PMCID:
PMC11109483
AbstractArticlePDF–2.9M
2.
FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis
Jing Xu, Rongtian Guo, Nasi Wen, Luping Li, Yong Yi, Jingzhen Chen, Zongyu He, Jian Yang, Zhi-Xiong Jim Xiao, Mengmeng Niu
PLoS Biol. 2023 Dec; 21(12): e3002446. Published online 2023 Dec 22. doi: 10.1371/journal.pbio.3002446
PMCID:
PMC10745200
AbstractArticlePDF–3.2M
3.
Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman
Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035
Correction in:
Cell. 2023 May 25; 186(11): 2492.
PMCID:
PMC10156175
AbstractArticle
4.
Extracellular matrix stiffness regulates degradation of MST2 via SCF βTrCP
Ana Paula Zen Petisco Fiore, Ana Maria Rodrigues, Helder Veras Ribeiro-Filho, Antonio Carlos Manucci, Pedro de Freitas Ribeiro, Mayara Carolinne Silva Botelho, Christine Vogel, Paulo Sergio Lopes-de-Oliveira, Michele Pagano, Alexandre Bruni-Cardoso
Biochim Biophys Acta Gen Subj. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Biochim Biophys Acta Gen Subj. 2022 Dec; 1866(12): 130238. Published online 2022 Aug 28. doi: 10.1016/j.bbagen.2022.130238
PMCID:
PMC9926743
AbstractArticlePDF–1.0M
5.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
6.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
7.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
8.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
9.
FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth
Mengmeng Niu, Jing Xu, Yang Liu, Yuhuang Li, Tao He, Liangping Ding, Yajun He, Yong Yi, Fengtian Li, Rongtian Guo, Ya Gao, Rui Li, Luping Li, Mengyuan Fu, Qingyong Hu, Yangkun Luo, Chunyan Zhang, Kewei Qin, Jianqiao Yi, Shuhan Yu, Jian Yang, Hu Chen, Liang Wang, Zhonghan Li, Biao Dong, Shiqian Qi, Liang Ouyang, Yujun Zhang, Yang Cao, Zhi-Xiong Jim Xiao
Nat Commun. 2021; 12: 5919. Published online 2021 Oct 11. doi: 10.1038/s41467-021-26222-x
PMCID:
PMC8505509
AbstractArticlePDF–7.1M
10.
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation
Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang
Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5
PMCID:
PMC8314547
AbstractArticlePDF–3.7M
11.
Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the  receptor protein of CRL2Prame complex
Wenjuan Zhang, Lihui Li, Lili Cai, Yupei Liang, Junfeng Xu, Yue Liu, Lisha Zhou, Chen Ding, Yanmei Zhang, Hu Zhao, Jun Qin, Zhimin Shao, Wenyi Wei, Lijun Jia
Cell Death Differ. 2021 Jun; 28(6): 1926–1940. Published online 2021 Jan 27. doi: 10.1038/s41418-020-00724-5
PMCID:
PMC8184998
AbstractArticlePDF–4.0M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1
Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi
J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162
PMCID:
PMC7948964
AbstractArticlePDF–2.7M
14.
An Amyotrophic Lateral Sclerosis-Associated Mutant of C21ORF2 Is Stabilized by NEK1-Mediated Hyperphosphorylation and the Inability to Bind FBXO3
Yasuaki Watanabe, Tadashi Nakagawa, Tetsuya Akiyama, Makiko Nakagawa, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Keiko Nakayama
iScience. 2020 Sep 25; 23(9): 101491. Published online 2020 Aug 21. doi: 10.1016/j.isci.2020.101491
PMCID:
PMC7481237
AbstractArticlePDF–4.2M
15.
The SCFFBXO3 ubiquitin E3 ligase regulates inflammation in atherosclerosis
Divay Chandra, James Londino, Shaun Alexander, Joseph S. Bednash, Yingze Zhang, Robert M. Friedlander, Grant Daskivich, Diane L. Carlisle, William R. Lariviere, Ana Carolina Igami Nakassa, Mark Ross, Claudette Croix, St., Toru Nyunoya, Frank Sciurba, Bill Chen, Rama K. Mallampalli
J Mol Cell Cardiol. Author manuscript; available in PMC 2020 Aug 13.
Published in final edited form as: J Mol Cell Cardiol. 2019 Jan; 126: 50–59. Published online 2018 Nov 16. doi: 10.1016/j.yjmcc.2018.11.006
PMCID:
PMC7425077
AbstractArticlePDF–1.4M
16.
Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease
Ruinan Shen, Xiaobei Zhao, Lu He, Yongbo Ding, Wei Xu, Suzhen Lin, Savannah Fang, Wanlin Yang, Kijung Sung, Brian Spencer, Robert A. Rissman, Ming Lei, Jianqing Ding, Chengbiao Wu
Transl Neurodegener. 2020; 9: 26. Published online 2020 Jun 18. doi: 10.1186/s40035-020-00206-1
PMCID:
PMC7301499
AbstractArticlePDF–14M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
19.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
20.
Nrf2 activation promotes lung cancer metastasis by inhibiting the degradation of Bach1
Luca Lignitto, Sarah E. LeBoeuf, Harrison Homer, Shaowen Jiang, Manor Askenazi, Triantafyllia R. Karakousi, Harvey I. Pass, Arjun J. Bhutkar, Aristotelis Tsirigos, Beatrix Ueberheide, Volkan I. Sayin, Thales Papagiannakopoulos, Michele Pagano
Cell. Author manuscript; available in PMC 2020 Jul 11.
Published in final edited form as: Cell. 2019 Jul 11; 178(2): 316–329.e18. Published online 2019 Jun 27. doi: 10.1016/j.cell.2019.06.003
PMCID:
PMC6625921
AbstractArticlePDF–3.1M

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