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Select item 110719621.

Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors

Marie S. Prevost, Hichem Bouchenaki, Nathalie Barilone, Marc Gielen, Pierre-Jean Corringer

Cell Mol Life Sci. 2021 Feb; 78(3): 1051–1064. Published online 2020 May 29. doi: 10.1007/s00018-020-03558-z

PMCID:: PMC11071962

Abstract Article PDF–4.2M

Select item 88970222.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79284914.

Maegan M. Weltzin, Andrew A. George, Ronald J. Lukas, Paul Whiteaker

PLoS One. 2021; 16(3): e0247825. Published online 2021 Mar 3. doi: 10.1371/journal.pone.0247825

PMCID:: PMC7928491

Abstract Article PDF–4.5M

Select item 73367615.

Novel variant in CHRNA4 with benign childhood epilepsy with centrotemporal spikes and contribution to precise medicine

Xiao Neng, Mao Xiao, Chen Yuanlu, Li Qinyan, Shu Li, Song Zhanyi

Mol Genet Genomic Med. 2020 Jul; 8(7): e1264. Published online 2020 Apr 28. doi: 10.1002/mgg3.1264

PMCID:: PMC7336761

Abstract Article PDF–635K

Select item 66717216.

Rats Harboring S284L Chrna4 Mutation Show Attenuation of Synaptic and Extrasynaptic GABAergic Transmission and Exhibit the Nocturnal Frontal Lobe Epilepsy Phenotype

Gang Zhu, Motohiro Okada, Shukuko Yoshida, Shinya Ueno, Fumiaki Mori, Tomoko Takahara, Ryo Saito, Yoshiki Miura, Akihiro Kishi, Masahiko Tomiyama, Akira Sato, Toshio Kojima, Goryu Fukuma, Koichi Wakabayashi, Koji Hase, Hiroshi Ohno, Hiroshi Kijima, Yukio Takano, Akihisa Mitsudome, Sunao Kaneko, Shinichi Hirose

J Neurosci. 2008 Nov 19; 28(47): 12465–12476. doi: 10.1523/JNEUROSCI.2961-08.2008

PMCID:: PMC6671721

Abstract Article PDF–918K

Select item 66489897.

Association of idiopathic generalized epilepsy with polymorphisms in the neuronal nicotinic acetylcholine receptor subunits

Cheng‐Chun Lee, I‐Ching Chou, Chang‐Hai Tsai, Lei Wan, Yu‐An Shu, Yuhsin Tsai, Tsai‐Chung Li, Fuu‐Jen Tsai

J Clin Lab Anal. 2007; 21(2): 67–70. Published online 2007 Mar 26. doi: 10.1002/jcla.20155

PMCID:: PMC6648989

Abstract Article PDF–119K

Select item 65966098.

Overdominant Effect of a CHRNA4 Polymorphism on Cingulo-Opercular Network Activity and Cognitive Control

Sepideh Sadaghiani, Bernard Ng, Andre Altmann, Jean-Baptiste Poline, Tobias Banaschewski, Arun L.W. Bokde, Uli Bromberg, Christian Büchel, Erin Burke Quinlan, Patricia Conrod, Sylvane Desrivières, Herta Flor, Vincent Frouin, Hugh Garavan, Penny Gowland, Jürgen Gallinat, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Hervé Lemaitre, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Luise Poustka, Sabina Millenet, Juliane H. Fröhner, Michael N. Smolka, Henrik Walter, Robert Whelan, Gunter Schumann, Valerio Napolioni, Michael Greicius

J Neurosci. 2017 Oct 4; 37(40): 9657–9666. doi: 10.1523/JNEUROSCI.0991-17.2017

PMCID:: PMC6596609

Abstract Article PDF–689K

Select item 65792029.

Human α4β2 Neuronal Nicotinic Acetylcholine Receptor in HEK 293 Cells: A Patch-Clamp Study

Bruno Buisson, Murali Gopalakrishnan, Stephen P. Arneric, James P. Sullivan, Daniel Bertrand

J Neurosci. 1996 Dec 15; 16(24): 7880–7891. doi: 10.1523/JNEUROSCI.16-24-07880.1996

PMCID:: PMC6579202

Abstract Article PDF–431K

Select item 613205910.

Structural principles of distinct assemblies of the human α4β2 nicotinic receptor

Richard M. Walsh, Jr., Soung-Hun Roh, Anant Gharpure, Claudio L. Morales-Perez, Jinfeng Teng, Ryan E. Hibbs

Nature. Author manuscript; available in PMC 2018 Nov 2.

Published in final edited form as: Nature. 2018 May; 557(7704): 261–265. Published online 2018 May 2. doi: 10.1038/s41586-018-0081-7

PMCID:: PMC6132059

Abstract Article PDF–2.9M

Select item 597895111.

The fifth subunit of the (α4β2)₂β2 nicotinic ACh receptor modulates maximal ACh responses

Karina New, Silvia Garcia Del Villar, Simone Mazzaferro, Constanza Alcaino, Isabel Bermudez

Br J Pharmacol. 2018 Jun; 175(11): 1822–1837. Published online 2017 Jul 14. doi: 10.1111/bph.13905

PMCID:: PMC5978951

Abstract Article PDF–1.5M

Select item 573016912.

The association between the nicotinic acetylcholine receptor α4 subunit gene (CHRNA4) rs1044396 and Internet gaming disorder in Korean male adults

Jo-Eun Jeong, Je-Keun Rhee, Tae-Min Kim, Su-Min Kwak, Sol-hee Bang, Hyun Cho, Young-Hoon Cheon, Jung Ah Min, Gil Sang Yoo, Kyudong Kim, Jung-Seok Choi, Sam-Wook Choi, Dai-Jin Kim

PLoS One. 2017; 12(12): e0188358. Published online 2017 Dec 14. doi: 10.1371/journal.pone.0188358

PMCID:: PMC5730169

Abstract Article PDF–1011K

Select item 547325013.

Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2)2-type nicotinic acetylcholine receptor responses

Ze-Jun Wang, Farah Deba, Tasnim S. Mohamed, David C. Chiara, Kara Ramos, Ayman K. Hamouda

J Biol Chem. 2017 Jun 16; 292(24): 9988–10001. Published online 2017 Apr 26. doi: 10.1074/jbc.M116.771246

PMCID:: PMC5473250

Abstract Article PDF–4.9M

Select item 543118414.

Compromised neuroplasticity in cigarette smokers under nicotine withdrawal is restituted by the nicotinic α₄β₂-receptor partial agonist varenicline

G. Batsikadze, W. Paulus, A. Hasan, J. Grundey, M.-F. Kuo, M. A. Nitsche

Sci Rep. 2017; 7: 1387. Published online 2017 May 3. doi: 10.1038/s41598-017-01428-6

PMCID:: PMC5431184

Abstract Article PDF–1.6M

Select item 541406115.

A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences

T E Thorgeirsson, S Steinberg, G W Reginsson, G Bjornsdottir, T Rafnar, I Jonsdottir, A Helgadottir, S Gretarsdottir, H Helgadottir, S Jonsson, S E Matthiasson, T Gislason, T Tyrfingsson, T Gudbjartsson, H J Isaksson, H Hardardottir, A Sigvaldason, L A Kiemeney, A Haugen, S Zienolddiny, H J Wolf, W A Franklin, A Panadero, J I Mayordomo, I P Hall, E Rönmark, B Lundbäck, A Dirksen, H Ashraf, J H Pedersen, G Masson, P Sulem, U Thorsteinsdottir, D F Gudbjartsson, K Stefansson

Mol Psychiatry. 2016 May; 21(5): 594–600. Published online 2016 Mar 8. doi: 10.1038/mp.2016.13

PMCID:: PMC5414061

Abstract Article PDF–364K

Select item 526752016.

The E Loop of the Transmitter Binding Site Is a Key Determinant of the Modulatory Effects of Physostigmine on Neuronal Nicotinic α4β2 Receptors

Xiaochun Jin, Megan M. McCollum, Allison L. Germann, Gustav Akk, Joe Henry Steinbach

Mol Pharmacol. 2017 Feb; 91(2): 100–109. Published online 2017 Feb. doi: 10.1124/mol.116.106484

PMCID:: PMC5267520

Abstract Article PDF–688K

Select item 516157317.

X-ray structure of the human a4ß2 nicotinic receptor

Claudio L. Morales-Perez, Colleen M. Noviello, Ryan E. Hibbs

Nature. Author manuscript; available in PMC 2017 Apr 3.

Published in final edited form as: Nature. 2016 Oct 20; 538(7625): 411–415. Published online 2016 Oct 3. doi: 10.1038/nature19785

PMCID:: PMC5161573

Abstract Article PDF–3.7M

Select item 509540118.

Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors

Akansha Jain, Alexander Kuryatov, Jingyi Wang, Theodore M. Kamenecka, Jon Lindstrom

J Biol Chem. 2016 Nov 4; 291(45): 23452–23463. Published online 2016 Sep 19. doi: 10.1074/jbc.M116.749150

PMCID:: PMC5095401

Abstract Article PDF–3.1M

Select item 508276419.

A spatial covariance ¹²³I-5IA-85380 SPECT study of α4β2 nicotinic receptors in Alzheimer's disease

Sean J. Colloby, Robert H. Field, David J. Wyper, John T. O'Brien, John-Paul Taylor

Neurobiol Aging. 2016 Nov; 47: 83–90. doi: 10.1016/j.neurobiolaging.2016.07.017

PMCID:: PMC5082764

Abstract Article PDF–864K

Select item 501790620.

Functional interaction between Lypd6 and nicotinic acetylcholine receptors

Maria Arvaniti, Majbrit M. Jensen, Neeraj Soni, Hong Wang, Anders B. Klein, Nathalie Thiriet, Lars H. Pinborg, Pretal P. Muldoon, Jacob Wienecke, M. Imad Damaj, Kristi A. Kohlmeier, Marjorie C. Gondré‐Lewis, Jens D. Mikkelsen, Morten S. Thomsen

J Neurochem. 2016 Sep; 138(6): 806–820. Published online 2016 Aug 15. doi: 10.1111/jnc.13718

PMCID:: PMC5017906

Abstract Article PDF–1.2M

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