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Items: 1 to 20 of 39

1.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
2.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
3.
Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing
Qiujia Chen, Alison M. Bates, Jocelyne N. Hanquier, Edward Simpson, Douglas B. Rusch, Ram Podicheti, Yunlong Liu, Ronald C. Wek, Evan M. Cornett, Millie M. Georgiadis
J Biol Chem. 2022 May; 298(5): 101894. Published online 2022 Apr 1. doi: 10.1016/j.jbc.2022.101894
PMCID:
PMC9062482
AbstractArticlePDF–2.5M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
The roles of the human SETMAR (Metnase) protein in illegitimate DNA recombination and non-homologous end joining repair
Michael Tellier, Ronald Chalmers
DNA Repair (Amst) 2019 Aug; 80: 26–35. doi: 10.1016/j.dnarep.2019.06.006
PMCID:
PMC6715855
AbstractArticle
6.
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome
Michael Tellier, Ronald Chalmers
Nucleic Acids Res. 2019 Jan 10; 47(1): 122–133. Published online 2018 Oct 17. doi: 10.1093/nar/gky937
PMCID:
PMC6326780
AbstractArticlePDF–1.9M
7.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
8.
SETMAR isoforms in glioblastoma: A matter of protein stability
Audrey Dussaussois-Montagne, Jérôme Jaillet, Laetitia Babin, Pierre Verrelle, Lucie Karayan-Tapon, Sylvaine Renault, Cécilia Rousselot-Denis, Ilyess Zemmoura, Corinne Augé-Gouillou
Oncotarget. 2017 Feb 7; 8(6): 9835–9848. Published online 2016 Dec 25. doi: 10.18632/oncotarget.14218
PMCID:
PMC5354774
AbstractArticlePDF–3.4M
9.
Metnase Mediates Loading of Exonuclease 1 onto Single Strand Overhang DNA for End Resection at Stalled Replication Forks
Hyun-Suk Kim, Elizabeth A. Williamson, Jac A. Nickoloff, Robert A. Hromas, Suk-Hee Lee
J Biol Chem. 2017 Jan 27; 292(4): 1414–1425. Published online 2016 Dec 14. doi: 10.1074/jbc.M116.745646
PMCID:
PMC5270484
AbstractArticlePDF–2.1M
10.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
11.
The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5’ End of SS-Overhang Cleavage
Hyun-Suk Kim, Sung-Kyung Kim, Robert Hromas, Suk-Hee Lee
PLoS One. 2015; 10(10): e0139418. Published online 2015 Oct 5. doi: 10.1371/journal.pone.0139418
PMCID:
PMC4593633
AbstractArticlePDF–7.7M
12.
A Proteomic Strategy Identifies Lysine Methylation of Splicing Factor snRNP70 by the SETMAR Enzyme
Scott M. Carlson, Kaitlyn E. Moore, Saumya M. Sankaran, Nicolas Reynoird, Joshua E. Elias, Or Gozani
J Biol Chem. 2015 May 8; 290(19): 12040–12047. Published online 2015 Mar 20. doi: 10.1074/jbc.M115.641530
PMCID:
PMC4424340
AbstractArticlePDF–1.3M
13.
New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing
Fernanda Luisa Basei, Gabriela Vaz Meirelles, Germanna Lima Righetto, Deivid Lucas dos Santos Migueleti, Juliana Helena Costa Smetana, Jörg Kobarg
Proteome Sci. 2015; 13: 11. Published online 2015 Feb 26. doi: 10.1186/s12953-015-0065-6
PMCID:
PMC4367857
AbstractArticlePDF–3.1M
14.
Potential Role for the Metnase Transposase Fusion Gene in Colon Cancer through the Regulation of Key Genes
Panagiotis Apostolou, Maria Toloudi, Eleni Kourtidou, Georgia Mimikakou, Ioanna Vlachou, Marina Chatziioannou, Vasiliki Kipourou, Ioannis Papasotiriou
PLoS One. 2014; 9(10): e109741. Published online 2014 Oct 15. doi: 10.1371/journal.pone.0109741
PMCID:
PMC4198141
AbstractArticlePDF–274K
15.
The DNA repair component Metnase regulates Chk1 stability
Elizabeth A Williamson, Yuehan Wu, Sudha Singh, Michael Byrne, Justin Wray, Suk-Hee Lee, Jac A Nickoloff, Robert Hromas
Cell Div. 2014; 9: 1. Published online 2014 Jul 9. doi: 10.1186/1747-1028-9-1
PMCID:
PMC4094783
AbstractArticlePDF–429K
16.
The DDN Catalytic Motif Is Required for Metnase Functions in Non-homologous End Joining (NHEJ) Repair and Replication Restart
Hyun-Suk Kim, Qiujia Chen, Sung-Kyung Kim, Jac A. Nickoloff, Robert Hromas, Millie M. Georgiadis, Suk-Hee Lee
J Biol Chem. 2014 Apr 11; 289(15): 10930–10938. Published online 2014 Feb 25. doi: 10.1074/jbc.M113.533216
PMCID:
PMC4036204
AbstractArticlePDF–1.4M
17.
Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing
Abhijit Rath, Robert Hromas, Arrigo De Benedetti
BMC Mol Biol. 2014; 15: 6. Published online 2014 Mar 22. doi: 10.1186/1471-2199-15-6
PMCID:
PMC3998112
AbstractArticlePDF–2.2M
18.
Chk1 phosphorylation of Metnase/SETMAR at Ser495 enhances DNA repair but decreases replication fork restart
Robert Hromas, Elizabeth Williamson, Sheema Fnu, Young-Ju Lee, Su-Jung Park, Brian D. Beck, Jin-Sam You, Andrei Laitao, Jac A. Nickoloff, Suk-Hee Lee
Oncogene. Author manuscript; available in PMC 2014 Mar 24.
Published in final edited form as: Oncogene. 2012 Sep 20; 31(38): 4245–4254. Published online 2012 Jan 9. doi: 10.1038/onc.2011.586
Correction in:
volume 33 on page 536
PMCID:
PMC3963179
AbstractArticlePDF–3.0M
19.
Biochemical characterization of Metnase's endonuclease activity and its role in NHEJ repair
Brian D. Beck, Sung-Sook Lee, Elizabeth Williamson, Robert A. Hromas, Suk-Hee Lee
Biochemistry. Author manuscript; available in PMC 2012 Jul 3.
Published in final edited form as: Biochemistry. 2011 May 24; 50(20): 4360–4370. Published online 2011 Apr 27. doi: 10.1021/bi200333k
PMCID:
PMC3388547
AbstractArticlePDF–3.8M
20.
Biochemical characterization of a SET and transposase fusion protein, Metnase (SETMAR) for its DNA binding and DNA cleavage activity
Yaritzabel Roman, Masahiko Oshige, Young-Ju Lee, Kristie Goodwin, Millie M. Georgiadis, Robert A. Hromas, Suk-Hee Lee
Biochemistry. Author manuscript; available in PMC 2012 Jun 13.
Published in final edited form as: Biochemistry. 2007 Oct 9; 46(40): 11369–11376. Published online 2007 Sep 18. doi: 10.1021/bi7005477
PMCID:
PMC3374406
AbstractArticlePDF–2.6M

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