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Items: 1 to 20 of 84

1.
Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity
Min H Chuah, Megan P Leask, Ruth K Topless, Gregory D Gamble, Nicholas A Sumpter, Lisa K Stamp, Tony R Merriman, Nicola Dalbeth
Arthritis Res Ther. 2024; 26: 45. Published online 2024 Feb 8. doi: 10.1186/s13075-024-03279-9
PMCID:
PMC10851571
AbstractArticlePDF–819K
2.
New insights into the inter-organ crosstalk mediated by ChREBP
Thais Carbinatti, Marion Régnier, Lucia Parlati, Fadila Benhamed, Catherine Postic
Front Endocrinol (Lausanne) 2023; 14: 1095440. Published online 2023 Feb 27. doi: 10.3389/fendo.2023.1095440
PMCID:
PMC10008936
AbstractArticlePDF–2.2M
3.
MLXIPL promotes the migration, invasion, and glycolysis of hepatocellular carcinoma cells by phosphorylation of mTOR
Xiaowei Chang, Chang Tian, Yuanyuan Jia, Yu Cai, Pu Yan
BMC Cancer. 2023; 23: 176. Published online 2023 Feb 21. doi: 10.1186/s12885-023-10652-5
PMCID:
PMC9945719
AbstractArticlePDF–8.2M
4.
HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis
Ashot Sargsyan, Ludivine Doridot, Sarah A. Hannou, Wenxin Tong, Harini Srinivasan, Rachael Ivison, Ruby Monn, Henry H. Kou, Jonathan M. Haldeman, Michelle Arlotto, Phillip J. White, Paul A. Grimsrud, Inna Astapova, Linus T. Tsai, Mark A. Herman
JCI Insight. 2023 Jan 10; 8(1): e153740. Published online 2023 Jan 10. doi: 10.1172/jci.insight.153740
PMCID:
PMC9870088
AbstractArticlePDF–5.4M
5.
Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP
Arturo Mendoza, Catherine Tang, Jinyoung Choi, Mariana Acuña, Maya Logan, Adriana G. Martin, Lujain Al-Sowaimel, Bhavna N. Desai, Danielle E. Tenen, Christopher Jacobs, Anna Lyubetskaya, Yulong Fu, Hong Liu, Linus Tsai, David E. Cohen, Douglas Forrest, Andrew A. Wilson, Anthony N. Hollenberg
Sci Signal. Author manuscript; available in PMC 2022 Feb 17.
Published in final edited form as: Sci Signal. 2021 Nov 16; 14(709): eabh3839. Published online 2021 Nov 16. doi: 10.1126/scisignal.abh3839
PMCID:
PMC8853622
AbstractArticlePDF–1.1M
6.
Transcription Factor ChREBP Mediates High Glucose-Evoked Increase in HIF-1α Content in Epithelial Cells of Renal Proximal Tubules
Aleksandra Owczarek, Katarzyna B. Gieczewska, Robert Jarzyna, Zuzanna Frydzinska, Katarzyna Winiarska
Int J Mol Sci. 2021 Dec; 22(24): 13299. Published online 2021 Dec 10. doi: 10.3390/ijms222413299
PMCID:
PMC8705933
AbstractArticlePDF–1.7M
7.
The Roles of Carbohydrate Response Element Binding Protein in the Relationship between Carbohydrate Intake and Diseases
Katsumi Iizuka
Int J Mol Sci. 2021 Nov; 22(21): 12058. Published online 2021 Nov 8. doi: 10.3390/ijms222112058
PMCID:
PMC8584459
AbstractArticlePDF–5.4M
8.
Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations
Danielle E. Haslam, Gina M. Peloso, Melanie Guirette, Fumiaki Imamura, Traci M. Bartz, Achilleas N. Pitsillides, Carol A. Wang, Ruifang Li-Gao, Jason M. Westra, Niina Pitkänen, Kristin L. Young, Mariaelisa Graff, Alexis C. Wood, Kim V.E. Braun, Jian’an Luan, Mika Kähönen, Jessica C. Kiefte-de Jong, Mohsen Ghanbari, Nathan Tintle, Rozenn N. Lemaitre, Dennis O. Mook-Kanamori, Kari North, Mika Helminen, Yasmin Mossavar-Rahmani, Linda Snetselaar, Lisa W. Martin, Jorma S. Viikari, Wendy H. Oddy, Craig E. Pennell, Frits R. Rosendall, M. Arfan Ikram, Andre G Uitterlinden, Bruce M. Psaty, Dariush Mozaffarian, Jerome I. Rotter, Kent D. Taylor, Terho Lehtimäki, Olli T. Raitakari, Kara A. Livingston, Trudy Voortman, Nita G. Forouhi, Nick J. Wareham, Renée de Mutsert, Steven S. Rich, JoAnn E. Manson, Samia Mora, Paul M. Ridker, Jordi Merino, James B. Meigs, Hassan S. Dashti, Daniel I. Chasman, Alice H. Lichtenstein, Caren E. Smith, Josée Dupuis, Mark A. Herman, Nicola M. McKeown
Circ Genom Precis Med. 2021 Aug; 14(4): e003288. Published online 2021 Jul 16. doi: 10.1161/CIRCGEN.120.003288
PMCID:
PMC8373451
AbstractArticlePDF–552K
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
11.
The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP–importin α interactions
Hunmin Jung, Tomomi Takeshima, Tsutomu Nakagawa, Karen S. MacMillan, R. Max Wynn, Hanzhi Wang, Haruhiko Sakiyama, Shuguang Wei, Yang Li, Richard K. Bruick, Bruce A. Posner, Jef K. De Brabander, Kosaku Uyeda
Biochem J. 2020 Sep 18; 477(17): 3253–3269. Prepublished online 2020 Aug 10. Published online 2020 Sep 10. doi: 10.1042/BCJ20200520
PMCID:
PMC7489895
AbstractArticlePDF–11M
12.
Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex
Kristina N. Schaefer, Mira I. Pronobis, Clara E. Williams, Shiping Zhang, Lauren Bauer, Dennis Goldfarb, Feng Yan, M. Ben Major, Mark Peifer
Mol Biol Cell. 2020 May 1; 31(10): 992–1014. doi: 10.1091/mbc.E19-11-0647
PMCID:
PMC7346726
AbstractArticlePDF–5.5M
13.
DDB1 E3 ligase controls dietary fructose-induced ChREBPα stabilization and liver steatosis via CRY1
Xin Tong, Deqiang Zhang, Omar Shabandri, Joon Oh, Ethan Jin, Kenneth Stamper, Meichan Yang, Zifeng Zhao, Lei Yin
Metabolism. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Metabolism. 2020 Jun; 107: 154222. Published online 2020 Apr 1. doi: 10.1016/j.metabol.2020.154222
PMCID:
PMC7282961
AbstractArticlePDF–2.4M
14.
Expressions of Carbohydrate Response Element Binding Protein and Glucose Transporters in Liver Cancer and Clinical Significance
Yu Lei, Qiaoling Hu, Jiang Gu
Pathol Oncol Res. 2020; 26(2): 1331–1340. Published online 2019 Aug 12. doi: 10.1007/s12253-019-00708-y
PMCID:
PMC7242283
AbstractArticlePDF–8.1M
15.
Genetic factors contributing to autism spectrum disorder in Williams-Beuren syndrome
Marta Codina-Sola, Mar Costa-Roger, Debora Pérez-García, Raquel Flores, Maria Gabriela Palacios-Verdú, Ivon Cusco, Luis Alberto Pérez-Jurado
J Med Genet. 2019 Dec; 56(12): 801–808. Published online 2019 Aug 14. doi: 10.1136/jmedgenet-2019-106080
PMCID:
PMC6929708
AbstractArticlePDF–951K
16.
The ubiquitination ligase SMURF2 reduces aerobic glycolysis and colorectal cancer cell proliferation by promoting ChREBP ubiquitination and degradation
Yakui Li, Dianqiang Yang, Na Tian, Ping Zhang, Yemin Zhu, Jian Meng, Ming Feng, Ying Lu, Qi Liu, Lingfeng Tong, Lei Hu, Lukuan Zhang, James Y. Yang, Lifang Wu, Xuemei Tong
J Biol Chem. 2019 Oct 4; 294(40): 14745–14756. Published online 2019 Aug 13. doi: 10.1074/jbc.RA119.007508
PMCID:
PMC6779433
AbstractArticlePDF–2.4M
17.
HCF-1 regulates de novo lipogenesis through a nutrient sensitive complex with ChREBP
Elizabeth A. Lane, Dong Wook Choi, Luisa Garcia-Haro, Zebulon G. Levine, Meghan Tedoldi, Suzanne Walker, Nika N. Danial
Mol Cell. Author manuscript; available in PMC 2020 Jul 25.
Published in final edited form as: Mol Cell. 2019 Jul 25; 75(2): 357–371.e7. Published online 2019 Jun 18. doi: 10.1016/j.molcel.2019.05.019
PMCID:
PMC6744259
AbstractArticlePDF–2.9M
18.
Carbohydrate response element binding protein (ChREBP) modulates the inflammatory response of mesangial cells in response to glucose
Yan Chen, Yan-Jun Wang, Ying Zhao, Jin-Cheng Wang
Biosci Rep. 2018 Dec 21; 38(6): BSR20180767. Prepublished online 2018 Nov 12. Published online 2018 Dec 7. doi: 10.1042/BSR20180767
PMCID:
PMC6435501
AbstractArticlePDF–886K
19.
H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids
Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth
Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.
Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9
PMCID:
PMC6420097
ArticlePDF–1.7M
20.
miR‐1322 regulates ChREBP expression via binding a 3′‐UTR variant (rs1051943)
Ying Zhang, Sen‐Lin Hu, Dong Hu, Jian‐Gang Jiang, Guang‐Lin Cui, Xing‐De Liu, Dao Wen Wang
J Cell Mol Med. 2018 Nov; 22(11): 5322–5332. Published online 2018 Aug 5. doi: 10.1111/jcmm.13805
PMCID:
PMC6201350
AbstractArticlePDF–1.1M

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