PMC Links for GEO Profiles (Select 7155090) - PMC

Links from GEO Profiles

Items: 1 to 20 of 76

<< First< Prev

Page of 4

Next >Last >>

Select item 103625791.

Congenital coralliform cataract is the predominant consequence of a recurrent mutation in the CRYGD gene

Kai-Jie Wang, Jue-Xue Wang, Jin-Da Wang, Meng Li, Jing-Shang Zhang, Ying-Yan Mao, Xiu-Hua Wan

Orphanet J Rare Dis. 2023; 18: 200. Published online 2023 Jul 21. doi: 10.1186/s13023-023-02816-0

PMCID:: PMC10362579

Abstract Article PDF–1.5M

Select item 88360492.

Insights to Human γD-Crystallin Unfolding by NMR Spectroscopy and Molecular Dynamics Simulations

Shu-Shun Hsueh, S.-S. (Steven) Wang, Shu-Han Chen, Chia-Lin Wang, W. (Josephine) Wu, Ta-Hsien Lin

Int J Mol Sci. 2022 Feb; 23(3): 1591. Published online 2022 Jan 29. doi: 10.3390/ijms23031591

PMCID:: PMC8836049

Abstract Article PDF–7.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79357504.

Assessing the Structures and Interactions of γD-Crystallin Deamidation Variants

Alex J. Guseman, Matthew J. Whitley, Jeremy J. González, Nityam Rathi, Mikayla Ambarian, Angela M. Gronenborn

Structure. Author manuscript; available in PMC 2022 Mar 4.

Published in final edited form as: Structure. 2021 Mar 4; 29(3): 284–291.e3. Published online 2020 Dec 1. doi: 10.1016/j.str.2020.11.006

PMCID:: PMC7935750

Abstract Article PDF–1.2M

Select item 75557775.

Cataract-Associated New Mutants S175G/H181Q of βΒ2-Crystallin and P24S/S31G of γD-Crystallin Are Involved in Protein Aggregation by Structural Changes

In-Kang Song, Seungjin Na, Eunok Paek, Kong-Joo Lee

Int J Mol Sci. 2020 Sep; 21(18): 6504. Published online 2020 Sep 5. doi: 10.3390/ijms21186504

PMCID:: PMC7555777

Abstract Article PDF–2.4M

Select item 75495526.

Increased hydrophobicity of CRYGD p.(Ala159ProfsTer9): Suspected cause of congenital cataracts in a large Chinese family

Meina Lin, Ying Jin, Xinren Chen, Yu Sui, Yan Li, Huan Li, Xiang Ni, Ning Zhao, Yongping Lu, Miao Jiang

Mol Genet Genomic Med. 2020 Oct; 8(10): e1436. Published online 2020 Jul 23. doi: 10.1002/mgg3.1436

PMCID:: PMC7549552

Abstract Article PDF–948K

Select item 67313887.

Temperature-Dependent Interactions Explain Normal and Inverted Solubility in a γD-Crystallin Mutant

Amir R. Khan, Susan James, Michelle K. Quinn, Irem Altan, Patrick Charbonneau, Jennifer J. McManus

Biophys J. 2019 Sep 3; 117(5): 930–937. Published online 2019 Jul 19. doi: 10.1016/j.bpj.2019.07.019

PMCID:: PMC6731388

Abstract Article PDF–913K

Select item 67006728.

Kinetic Stability of Long-Lived Human Lens γ-Crystallins and Their Isolated Double Greek Key Domains

Ishara A. Mills-Henry, Shannon L. Thol, Melissa S. Kosinski-Collins, Eugene Serebryany, Jonathan A. King

Biophys J. 2019 Jul 23; 117(2): 269–280. Published online 2019 Jun 14. doi: 10.1016/j.bpj.2019.06.006

PMCID:: PMC6700672

Abstract Article PDF–1.3M

Select item 65900759.

Reactive cysteine residues in the oxidative dimerization and Cu²⁺ induced aggregation of human γD-crystallin: Implications for age-related cataract

Srinivasagan Ramkumar, Xingjun Fan, Benlian Wang, Sichun Yang, Vincent M. Monnier

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2018 Nov; 1864(11): 3595–3604. Published online 2018 Aug 18. doi: 10.1016/j.bbadis.2018.08.021

PMCID:: PMC6590075

Abstract Article PDF–877K

Select item 624086410.

Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation

Eugene Serebryany, Shuhuai Yu, Sunia A. Trauger, Bogdan Budnik, Eugene I. Shakhnovich

J Biol Chem. 2018 Nov 16; 293(46): 17997–18009. Published online 2018 Sep 21. doi: 10.1074/jbc.RA118.004551

PMCID:: PMC6240864

Abstract Article PDF–1.8M

Select item 542418111.

Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH

Jennifer C. Boatz, Matthew J. Whitley, Mingyue Li, Angela M. Gronenborn, Patrick C. A. van der Wel

Nat Commun. 2017; 8: 15137. Published online 2017 May 5. doi: 10.1038/ncomms15137

PMCID:: PMC5424181

Abstract Article PDF–2.1M

Select item 500928512.

An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin

Eugene Serebryany, Jaie C. Woodard, Bharat V. Adkar, Mohammed Shabab, Jonathan A. King, Eugene I. Shakhnovich

J Biol Chem. 2016 Sep 2; 291(36): 19172–19183. Published online 2016 Jul 14. doi: 10.1074/jbc.M116.735977

PMCID:: PMC5009285

Abstract Article PDF–2.8M

Select item 494177413.

Aggregation of Trp > Glu point mutants of human gamma‐D crystallin provides a model for hereditary or UV‐induced cataract

Eugene Serebryany, Takumi Takata, Erika Erickson, Nathaniel Schafheimer, Yongting Wang, Jonathan A. King

Protein Sci. 2016 Jun; 25(6): 1115–1128. Published online 2016 Apr 18. doi: 10.1002/pro.2924

PMCID:: PMC4941774

Abstract Article PDF–2.1M

Select item 475919614.

Single-molecule Force Spectroscopy Predicts a Misfolded, Domain-swapped Conformation in human γD-Crystallin Protein

Sergi Garcia-Manyes, David Giganti, Carmen L. Badilla, Ainhoa Lezamiz, Judit Perales-Calvo, Amy E. M. Beedle, Julio M. Fernández

J Biol Chem. 2016 Feb 19; 291(8): 4226–4235. Published online 2015 Dec 24. doi: 10.1074/jbc.M115.673871

PMCID:: PMC4759196

Abstract Article PDF–2.1M

Select item 470211715.

Novel mutations in CRYGD are associated with congenital cataracts in Chinese families

Guoxing Yang, Zhimin Chen, Wulin Zhang, Zhiqiang Liu, Jialiang Zhao

Sci Rep. 2016; 6: 18912. Published online 2016 Jan 6. doi: 10.1038/srep18912

PMCID:: PMC4702117

Abstract Article PDF–654K

Select item 449307316.

A Novel Insertion Variant of CRYGD Is Associated with Congenital Nuclear Cataract in a Chinese Family

Xiaotong Zhuang, Lianqing Wang, Zixun Song, Wei Xiao

PLoS One. 2015; 10(7): e0131471. Published online 2015 Jul 6. doi: 10.1371/journal.pone.0131471

PMCID:: PMC4493073

Abstract Article PDF–4.0M

Select item 441685317.

Wild-type Human γD-crystallin Promotes Aggregation of Its Oxidation-mimicking, Misfolding-prone W42Q Mutant

Eugene Serebryany, Jonathan A. King

J Biol Chem. 2015 May 1; 290(18): 11491–11503. Published online 2015 Mar 18. doi: 10.1074/jbc.M114.621581

PMCID:: PMC4416853

Abstract Article PDF–2.7M

Select item 424598418.

Acetylation of Gly1 and Lys2 Promotes Aggregation of Human γD-Crystallin

Michael A. DiMauro, Sandip K. Nandi, Cibin T. Raghavan, Rajiv Kumar Kar, Benlian Wang, Anirban Bhunia, Ram H. Nagaraj, Ashis Biswas

Biochemistry. 2014 Nov 25; 53(46): 7269–7282. Published online 2014 Oct 30. doi: 10.1021/bi501004y

PMCID:: PMC4245984

Abstract Article PDF–8.3M

Select item 424082219.

Exome sequencing identifies novel and recurrent mutations in GJA8 and CRYGD associated with inherited cataract

Donna S Mackay, Thomas M Bennett, Susan M Culican, Alan Shiels

Hum Genomics. 2014; 8(1): 19. Published online 2014 Nov 18. doi: 10.1186/s40246-014-0019-6

PMCID:: PMC4240822

Abstract Article PDF–641K

Select item 394584020.

An alternative structural isoform in amyloid-like aggregates formed from thermally denatured human γD-crystallin

Sean D Moran, Tianqi O Zhang, Martin T Zanni

Protein Sci. 2014 Mar; 23(3): 321–331. Published online 2014 Feb 4. doi: 10.1002/pro.2422

PMCID:: PMC3945840

Abstract Article PDF–480K

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 76

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity