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Items: 1 to 20 of 57

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
NLRX1 Mediates the Disruption of Intestinal Mucosal Function Caused by Porcine Astrovirus Infection via the Extracellular Regulated Protein Kinases/Myosin Light–Chain Kinase (ERK/MLCK) Pathway
Jie Tao, Jinghua Cheng, Ying Shi, Benqiang Li, Pan Tang, Jiajie Jiao, Huili Liu
Cells. 2024 Jun; 13(11): 913. Published online 2024 May 25. doi: 10.3390/cells13110913
PMCID:
PMC11171766
AbstractArticlePDF–2.0M
3.
NLRX1: Versatile functions of a mitochondrial NLR protein that controls mitophagy
Paul Y. Bi, Samuel A. Killackey, Linus Schweizer, Stephen E. Girardin
Biomed J. 2024 Feb; 47(1): 100635. Published online 2023 Aug 11. doi: 10.1016/j.bj.2023.100635
PMCID:
PMC10837482
AbstractArticlePDF–1.3M
4.
NLRX1 can counteract innate immune response induced by an external stimulus favoring HBV infection by competitive inhibition of MAVS-RLRs signaling in HepG2-NTCP cells
Qian Jiao, Wenxiong Xu, Xiaoyan Guo, Huiyuan Liu, Baolin Liao, Xiang Zhu, Chuming Chen, Fangji Yang, Lina Wu, Chan Xie, Liang Peng
Sci Prog. 2021 Oct-Dec; 104(4): 00368504211058036. Published online 2021 Nov 26. doi: 10.1177/00368504211058036
PMCID:
PMC10461377
AbstractArticlePDF–2.8M
5.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
6.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
7.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
8.
Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation
Yan-Ran Xu, Meng-Ling Shi, Yu Zhang, Na Kong, Cong Wang, Yi-Feng Xiao, Shi-Shen Du, Qi-Yun Zhu, Cao-Qi Lei
Proc Natl Acad Sci U S A. 2022 Jun 28; 119(26): e2122805119. Published online 2022 Jun 21. doi: 10.1073/pnas.2122805119
PMCID:
PMC9245648
AbstractArticlePDF–2.6M
9.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
10.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Schendzielorz, Laura Melchionda, Wignand W.D. Mühlhäuser, Bettina Knapp, Jakob D. Busch, Sebastian B. Stiller, Stefan Dannenmaier, Caroline Lindau, Mariya Licheva, Christopher Eickhorst, Riccardo Galbusera, Ralf M. Zerbes, Michael T. Ryan, Claudine Kraft, Vera Kozjak-Pavlovic, Friedel Drepper, Sven Dennerlein, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Cell Metab. 2021 Dec 7; 33(12): 2464–2483.e18. doi: 10.1016/j.cmet.2021.11.001
PMCID:
PMC8664129
AbstractArticle
11.
Nlrx1-Regulated Defense and Metabolic Responses to Aspergillus fumigatus Are Morphotype and Cell Type Specific
Bridget Kastelberg, Tariq Ayubi, Nuria Tubau-Juni, Andrew Leber, Raquel Hontecillas, Josep Bassaganya-Riera, Shiv D. Kale
Front Immunol. 2021; 12: 749504. Published online 2021 Nov 1. doi: 10.3389/fimmu.2021.749504
PMCID:
PMC8591139
AbstractArticlePDF–8.1M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
Long noncoding RNA NKILA transferred by astrocyte-derived extracellular vesicles protects against neuronal injury by upregulating NLRX1 through binding to mir-195 in traumatic brain injury
Bin He, Wei Chen, Jingsong Zeng, Wusong Tong, Ping Zheng
Aging (Albany NY) 2021 Mar 31; 13(6): 8127–8145. Published online 2021 Mar 3. doi: 10.18632/aging.202618
PMCID:
PMC8034961
AbstractArticlePDF–2.3M
14.
Focusing on the Cell Type Specific Regulatory Actions of NLRX1
Tünde Fekete, Dóra Bencze, Eduárd Bíró, Szilvia Benkő, Kitti Pázmándi
Int J Mol Sci. 2021 Feb; 22(3): 1316. Published online 2021 Jan 28. doi: 10.3390/ijms22031316
PMCID:
PMC7865811
AbstractArticlePDF–4.7M
15.
NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart
Hong Zhang, Yang Xiao, Rianne Nederlof, Diane Bakker, Pengbo Zhang, Stephen E. Girardin, Markus W. Hollmann, Nina C. Weber, Sander M. Houten, Michel van Weeghel, Richard G. Kibbey, Coert J. Zuurbier
Front Immunol. 2020; 11: 591815. Published online 2020 Dec 11. doi: 10.3389/fimmu.2020.591815
PMCID:
PMC7759503
AbstractArticlePDF–1.6M
16.
Behind the Scenes: Nod-Like Receptor X1 Controls Inflammation and Metabolism
Tiia Snäkä, Nicolas Fasel
Front Cell Infect Microbiol. 2020; 10: 609812. Published online 2020 Dec 4. doi: 10.3389/fcimb.2020.609812
PMCID:
PMC7746548
AbstractArticlePDF–2.4M
17.
Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding
Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari
Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245
PMCID:
PMC7372081
AbstractArticlePDF–2.0M
18.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
19.
MiR-423-5p Regulates Cells Apoptosis and Extracellular Matrix Degradation via Nucleotide-Binding, Leucine-Rich Repeat Containing X1 (NLRX1) in Interleukin 1 beta (IL-1β)-Induced Human Nucleus Pulposus Cells
Hanrong Xu, Liefeng Ji, Chunhua Yu, Qiming Chen, Qiangqiang Ge, Yinjiang Lu
Med Sci Monit. 2020; 26: e922497-1–e922497-9. Prepublished online 2020 Mar 27. Published online 2020 May 18. doi: 10.12659/MSM.922497
PMCID:
PMC7254941
AbstractArticlePDF–1.0M
20.
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING
Xiaobo Luo, Christopher R. Donnelly, Wang Gong, Blake R. Heath, Yuning Hao, Lorenza A. Donnelly, Toktam Moghbeli, Yee Sun Tan, Xin Lin, Emily Bellile, Benjamin A. Kansy, Thomas E. Carey, J. Chad Brenner, Lei Cheng, Peter J. Polverini, Meredith A. Morgan, Haitao Wen, Mark E. Prince, Robert L. Ferris, Yuying Xie, Simon Young, Gregory T. Wolf, Qianming Chen, Yu L. Lei
J Clin Invest. 2020 Apr 1; 130(4): 1635–1652. Published online 2020 Feb 24. doi: 10.1172/JCI129497
PMCID:
PMC7108911
AbstractArticlePDF–5.4M

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