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Select item 97701501.

Blocking MG53^S255 Phosphorylation Protects Diabetic Heart From Ischemic Injury

Fengxiang Lv, Yingfan Wang, Dan Shan, Sile Guo, Gengjia Chen, Li Jin, Wen Zheng, Han Feng, Xiaohu Zeng, Shuo Zhang, Yan Zhang, Xinli Hu, Rui-Ping Xiao

Circ Res. 2022 Dec 2; 131(12): 962–976. Published online 2022 Nov 7. doi: 10.1161/CIRCRESAHA.122.321055

PMCID:: PMC9770150

Abstract Article PDF–7.3M

Select item 92581322.

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD–associated UBQLN2 mutants

Laura Strohm, Zehan Hu, Yongwon Suk, Alina Rühmkorf, Erin Sternburg, Vanessa Gattringer, Henrick Riemenschneider, Riccardo Berutti, Elisabeth Graf, Jochen H Weishaupt, Monika S Brill, Angelika B Harbauer, Dorothee Dormann, Jörn Dengjel, Dieter Edbauer, Christian Behrends

Life Sci Alliance. 2022 Nov; 5(11): e202101327. Published online 2022 Jul 1. doi: 10.26508/lsa.202101327

PMCID:: PMC9258132

Abstract Article PDF–5.9M

Select item 91197363.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90560264.

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis

Fenglong Jiao, Clinton Yu, Andrew Wheat, Xiaorong Wang, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2022 Apr 30.

Published in final edited form as: Anal Chem. 2022 Mar 15; 94(10): 4236–4242. Published online 2022 Mar 2. doi: 10.1021/acs.analchem.1c04485

PMCID:: PMC9056026

Abstract Article PDF–1.0M

Select item 87021705.

The role of serum creatine kinase levels in anterior cervical spinal surgery: Change trends and risk factors

Peiming Sang, Yanyan Ma, Binhui Chen, Ming Zhang

Medicine (Baltimore) 2021 Dec 23; 100(51): e28300. Published online 2021 Dec 23. doi: 10.1097/MD.0000000000028300

PMCID:: PMC8702170

Abstract Article PDF–198K

Select item 85360476.

CKM Gene rs8111989 Polymorphism and Power Athlete Status

Valentina Ginevičienė, Audronė Jakaitienė, Algirdas Utkus, Elliott C. R. Hall, Ekaterina A. Semenova, Liliya B. Andryushchenko, Andrey K. Larin, Ethan Moreland, Edward V. Generozov, Ildus I. Ahmetov

Genes (Basel) 2021 Oct; 12(10): 1499. Published online 2021 Sep 25. doi: 10.3390/genes12101499

PMCID:: PMC8536047

Abstract Article PDF–261K

Select item 83641817.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79348609.

Acetylation of muscle creatine kinase negatively impacts high-energy phosphotransfer in heart failure

Matthew A. Walker, Juan Chavez, Outi Villet, Xiaoting Tang, Andrew Keller, James E. Bruce, Rong Tian

JCI Insight. 2021 Feb 8; 6(3): e144301. Published online 2021 Feb 8. doi: 10.1172/jci.insight.144301

PMCID:: PMC7934860

Abstract Article PDF–5.6M

Select item 775805010.

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele

PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975

PMCID:: PMC7758050

Abstract Article PDF–4.2M

Select item 765868511.

Tumor Suppressor LINC02487 Inhibits Oral Squamous Cell Carcinoma Cell Migration and Invasion Through the USP17–SNAI1 Axis

Lu Feng, Jianjun Zhang, Minglei Sun, Feng Qiu, Wantao Chen, Weiliu Qiu

Front Oncol. 2020; 10: 559808. Published online 2020 Oct 29. doi: 10.3389/fonc.2020.559808

PMCID:: PMC7658685

Abstract Article PDF–3.3M

Select item 753767712.

Population-Wide Duchenne Muscular Dystrophy Carrier Detection by CK and Molecular Testing

Shuai Han, Hong Xu, Jinxian Zheng, Junhui Sun, Xue Feng, Yue Wang, Wen Ye, Qing Ke, Yanwei Ren, Shulie Yao, Songying Zhang, Jianfen Chen, Robert C. Griggs, Zhengyan Zhao, Ming Qi, Michele A. Gatheridge

Biomed Res Int. 2020; 2020: 8396429. Published online 2020 Sep 27. doi: 10.1155/2020/8396429

PMCID:: PMC7537677

Abstract Article PDF–1.5M

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 654268714.

Localized rest and stress human cardiac creatine kinase reaction kinetics at 3 T

William T. Clarke, Mark A. Peterzan, Jennifer J. Rayner, Rana A. Sayeed, Mario Petrou, George Krasopoulos, Hannah A. Lake, Betty Raman, William D. Watson, Pete Cox, Moritz J. Hundertmark, Andrew P. Apps, Craig A. Lygate, Stefan Neubauer, Oliver J. Rider, Christopher T. Rodgers

NMR Biomed. 2019 Jun; 32(6): e4085. Published online 2019 Mar 28. doi: 10.1002/nbm.4085

PMCID:: PMC6542687

Abstract Article PDF–1.3M

Select item 629810515.

Ubiquilin 2 modulates ALS/FTD-linked FUS–RNA complex dynamics and stress granule formation

Elizabeth J. Alexander, Amirhossein Ghanbari Niaki, Tao Zhang, Jaya Sarkar, Yang Liu, Raja Sekhar Nirujogi, Akhilesh Pandey, Sua Myong, Jiou Wang

Proc Natl Acad Sci U S A. 2018 Dec 4; 115(49): E11485–E11494. Published online 2018 Nov 15. doi: 10.1073/pnas.1811997115

PMCID:: PMC6298105

Abstract Article PDF–3.7M

Select item 610685916.

Increased Creatine Kinase with Statin Treatment May Identify Statin-Associated Muscle Symptoms

Beth A. Taylor, Gregory Panza, Paul D. Thompson

Int J Cardiol. Author manuscript; available in PMC 2018 Aug 23.

Published in final edited form as: Int J Cardiol. 2016 Apr 15; 209: 12–13. Published online 2016 Feb 3. doi: 10.1016/j.ijcard.2016.02.028

PMCID:: PMC6106859

Article PDF–47K

Select item 555729217.

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions

Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik

Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.

Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834

PMCID:: PMC5557292

Abstract Article PDF–3.4M

Select item 555618718.

Significant Association of Serum Adiponectin and Creatine Kinase-MB Levels in ST-Segment Elevation Myocardial Infarction

Tomoaki Natsukawa, Norikazu Maeda, Shiro Fukuda, Masaya Yamaoka, Yuya Fujishima, Hirofumi Nagao, Fumi Sato, Hitoshi Nishizawa, Hirotaka Sawano, Yasuyuki Hayashi, Tohru Funahashi, Tatsuro Kai, Iichiro Shimomura

J Atheroscler Thromb. 2017 Aug 1; 24(8): 793–803. doi: 10.5551/jat.38232

PMCID:: PMC5556187

Abstract Article PDF–454K

Select item 555562819.

Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro

Sevasti Zervou, Hannah J. Whittington, Philip J. Ostrowski, Fang Cao, Jack Tyler, Hannah A. Lake, Stefan Neubauer, Craig A. Lygate

PLoS One. 2017; 12(8): e0182994. Published online 2017 Aug 14. doi: 10.1371/journal.pone.0182994

PMCID:: PMC5555628

Abstract Article PDF–1.7M

Select item 555049920.

Interrelationship of rotavirus infection and Creatine Kinase-MB isoenzyme levels in children hospitalized with acute gastroenteritis in Guangzhou, China, 2012–2015

Jianbin Zheng, Haiqing Zheng, Ramit Kumar Gupta, Huixian Li, Hui Shi, Liyan Pan, Sitang Gong, Huiying Liang

Sci Rep. 2017; 7: 7674. Published online 2017 Aug 9. doi: 10.1038/s41598-017-07636-4

PMCID:: PMC5550499

Abstract Article PDF–1.0M

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