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Items: 1 to 20 of 93

1.
Characterization of different-sized human αA-crystallin homomers and implications to Asp151 isomerization
Jiayue Sun, Toshiya Matsubara, Tamaki Koide, Kirsten J. Lampi, Larry L. David, Takumi Takata
PLoS One. 2024; 19(7): e0306856. Published online 2024 Jul 11. doi: 10.1371/journal.pone.0306856
PMCID:
PMC11238991
AbstractArticlePDF–1.9M
2.
Expression of αA-crystallin (CRYAA) in vivo and in vitro models of age-related cataract and the effect of its silencing on HLEB3 cells
Xiaoling Ma, Yi Nan, Can Huang, Xiangyang Li, Yifan Yang, Wenjie Jiang, Mengyi Ye, Qian Liu, Yang Niu, Ling Yuan
Aging (Albany NY) 2023 May 31; 15(10): 4498–4509. Published online 2023 May 28. doi: 10.18632/aging.204754
PMCID:
PMC10258011
AbstractArticlePDF–1.0M
3.
Structural and functional analysis of SNP rs76740365 G>A in exon-3 of the alpha A-crystallin gene in lens epithelial cells
Zhennan Zhao, Yang Sun, Qi Fan, Yongxiang Jiang, Yi Lu
Mol Vis. 2022; 28: 317–330. Published online 2022 Oct 1.
PMCID:
PMC9603911
AbstractArticlePDF–3.6M
4.
Racemization in cataractous lens from diabetic and aging individuals: analysis of Asp 58 residue in αA-crystallin
Xiang-Jia Zhu, Ke-Ke Zhang, Wen-Wen He, Jiao Qi, Yi Lu
Aging (Albany NY) 2021 Jun 15; 13(11): 15255–15268. Published online 2021 Jun 7. doi: 10.18632/aging.203086
PMCID:
PMC8221327
AbstractArticlePDF–1.3M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Glycation-mediated inter-protein cross-linking is promoted by chaperone–client complexes of α-crystallin: Implications for lens aging and presbyopia
Sandip K. Nandi, Rooban B. Nahomi, Johanna Rankenberg, Marcus A. Glomb, Ram H. Nagaraj
J Biol Chem. 2020 Apr 24; 295(17): 5701–5716. Published online 2020 Mar 17. doi: 10.1074/jbc.RA120.012604
PMCID:
PMC7186181
AbstractArticlePDF–3.9M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
The structure and oxidation of the eye lens chaperone αA-crystallin
Christoph J. O. Kaiser, Carsten Peters, Philipp W. N. Schmid, Maria Stavropoulou, Juan Zou, Vinay Dahiya, Evgeny V. Mymrikov, Beate Rockel, Sam Asami, Martin Haslbeck, Juri Rappsilber, Bernd Reif, Martin Zacharias, Johannes Buchner, Sevil Weinkauf
Nat Struct Mol Biol. Author manuscript; available in PMC 2020 Jul 24.
Published in final edited form as: Nat Struct Mol Biol. 2019 Dec 1; 26(12): 1141–1150. Published online 2019 Dec 2. doi: 10.1038/s41594-019-0332-9
PMCID:
PMC7115824
AbstractArticlePDF–5.9M
9.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
10.
Structural and functional consequences of age-related isomerization in α-crystallins
Yana A. Lyon, Miranda P. Collier, Dylan L. Riggs, Matteo T. Degiacomi, Justin L. P. Benesch, Ryan R. Julian
J Biol Chem. 2019 May 10; 294(19): 7546–7555. Published online 2019 Feb 25. doi: 10.1074/jbc.RA118.007052
PMCID:
PMC6514633
AbstractArticlePDF–1.8M
11.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
AbstractArticlePDF–1.3M
12.
Endogenous Cell Type-Specific DISC1 Interactomes Reveal Protein Networks Associated to Neurodevelopmental Disorders
Brent Wilkinson, Oleg Evgrafov, DongQing Zheng, Nicolas Hartel, James A. Knowles, Nicholas A. Graham, Justin Ichida, Marcelo P. Coba
Biol Psychiatry. Author manuscript; available in PMC 2020 Feb 15.
Published in final edited form as: Biol Psychiatry. 2019 Feb 15; 85(4): 305–316. Published online 2018 May 23. doi: 10.1016/j.biopsych.2018.05.009
PMCID:
PMC6251761
AbstractArticlePDF–1.6M
13.
A novel mutation in the CRYAA gene associated with congenital cataract and microphthalmia in a Chinese family
Zixun Song, Nuo Si, Wei Xiao
BMC Med Genet. 2018; 19: 190. Published online 2018 Oct 19. doi: 10.1186/s12881-018-0695-5
PMCID:
PMC6194747
AbstractArticlePDF–1.1M
14.
A specific phosphorylation regulates the protective role of αA-crystallin in diabetes
Anne Ruebsam, Jennifer E. Dulle, Angela M. Myers, Dhananjay Sakrikar, Katelyn M. Green, Naheed W. Khan, Kevin Schey, Patrice E. Fort
JCI Insight. 2018 Feb 22; 3(4): e97919. Published online 2018 Feb 22. doi: 10.1172/jci.insight.97919
PMCID:
PMC5916248
AbstractArticlePDF–3.5M
15.
Racemization at the Asp 58 residue in αA‐crystallin from the lens of high myopic cataract patients
Xiang‐jia Zhu, Ke‐ke Zhang, Wen‐wen He, Yu Du, Michelle Hooi, Yi Lu
J Cell Mol Med. 2018 Feb; 22(2): 1118–1126. Published online 2017 Oct 10. doi: 10.1111/jcmm.13363
PMCID:
PMC5783843
AbstractArticlePDF–404K
16.
Two novel mutations identified in ADCC families impair crystallin protein distribution and induce apoptosis in human lens epithelial cells
Li Li, Da-Bei Fan, Ya-Ting Zhao, Yun Li, De-Qian Kong, Fang-Fei Cai, Guang-Ying Zheng
Sci Rep. 2017; 7: 17848. Published online 2017 Dec 19. doi: 10.1038/s41598-017-18222-z
PMCID:
PMC5736644
AbstractArticlePDF–2.1M
17.
Association of alpha A-crystallin polymorphisms with susceptibility to nuclear age-related cataract in a Han Chinese population
Zhennan Zhao, Qi Fan, Peng Zhou, HongFei Ye, Lei Cai, Yi Lu
BMC Ophthalmol. 2017; 17: 133. Published online 2017 Jul 29. doi: 10.1186/s12886-017-0529-9
PMCID:
PMC5534246
AbstractArticlePDF–748K
18.
Correlations of single nucleotide polymorphisms of CRYAA and CRYAB genes with the risk and clinicopathological features of children suffering from congenital cataract
Xian-Jin Cui, Feng-Yan Lv, Feng-Hua Li, Kun Zeng
Medicine (Baltimore) 2017 Jun; 96(25): e7158. Published online 2017 Jun 23. doi: 10.1097/MD.0000000000007158
PMCID:
PMC5484201
AbstractArticlePDF–263K
19.
A silent mutation in human alpha-A crystallin gene in patients with age-related nuclear or cortical cataract
Bharani K Mynampati, Thungapathra Muthukumarappa, Sujata Ghosh, Jagat Ram
Bosn J Basic Med Sci. 2017 May; 17(2): 114–119. doi: 10.17305/bjbms.2017.1745
PMCID:
PMC5474104
AbstractArticlePDF–526K
20.
An alternative splice variant of human αA-crystallin modulates the oligomer ensemble and the chaperone activity of α-crystallins
Waldemar Preis, Annika Bestehorn, Johannes Buchner, Martin Haslbeck
Cell Stress Chaperones. 2017 Jul; 22(4): 541–552. Published online 2017 Feb 18. doi: 10.1007/s12192-017-0772-2
PMCID:
PMC5465031
AbstractArticlePDF–1.0M

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