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Select item 112819851.

Clinical features, treatment, and follow-up of OPPG and high-bone-mass disorders: LRP5 is a key regulator of bone mass

Na Ren, Shanshan Lv, Xiang Li, Chong Shao, Ziyuan Wang, Yazhao Mei, Wendi Yang, Wenzhen Fu, Yunqiu Hu, Ling Sha, Weiwei Hu, Zhenlin Zhang, Chun Wang

Osteoporos Int. 2024; 35(8): 1395–1406. Published online 2024 Apr 16. doi: 10.1007/s00198-024-07080-x

PMCID:: PMC11281985

Abstract Article PDF–1.4M

Select item 111313062.

Evolutionary and functional analyses of LRP5 in archaic and extant modern humans

Neus Roca-Ayats, Iago Maceda, Carlos David Bruque, Núria Martínez-Gil, Natàlia Garcia-Giralt, Mónica Cozar, Leonardo Mellibovsky, Wim Van Hul, Oscar Lao, Daniel Grinberg, Susanna Balcells

Hum Genomics. 2024; 18: 53. Published online 2024 May 27. doi: 10.1186/s40246-024-00616-6

PMCID:: PMC11131306

Abstract Article PDF–2.2M

Select item 108322143.

Relationship between polymorphisms and mutations at rs7125942 and rs3736228 of LRP5 gene and bone metabolism in postmenopausal women

Jun Li, Ya Li, Siyuan Li, Yunqiu Lu, Partab Rai

J Orthop Surg Res. 2024; 19: 104. Published online 2024 Feb 1. doi: 10.1186/s13018-024-04579-1

PMCID:: PMC10832214

Abstract Article PDF–1.2M

Select item 107028524.

Human Placental LRP5 and Sclerostin are Increased in Gestational Diabetes Mellitus Pregnancies

Anna Papadopoulou, Eirini Thymara, Eirini Maratou, George Kanellopoulos, Vasiliki Papaevangelou, Sophia Kalantaridou, Spyridon Kanellakis, Pinelopi Triantafyllidou, George Valsamakis, George Mastorakos

J Clin Endocrinol Metab. 2023 Oct; 108(10): 2666–2675. Published online 2023 Mar 22. doi: 10.1210/clinem/dgad164

PMCID:: PMC10702852

Abstract Article

Select item 106855525.

Genetic detection of two novel LRP5 pathogenic variants in patients with familial exudative vitreoretinopathy

Jiayu Li, Chanjuan Wang, Shaochi Zhang, Bo Cai, Bo Pan, Caihong Sun, Xiaolong Qi, Chunmei Ma, Wei Fang, Kangxin Jin, Xiaojun Bi, Zibing Jin, Wenjuan Zhuang

BMC Ophthalmol. 2023; 23: 489. Published online 2023 Nov 29. doi: 10.1186/s12886-023-03243-2

PMCID:: PMC10685552

Abstract Article PDF–11M

Select item 106062546.

LRP5, Bone Mass Polymorphisms and Skeletal Disorders

Jake Littman, Wentian Yang, Jon Olansen, Chanika Phornphutkul, Roy K. Aaron

Genes (Basel) 2023 Oct; 14(10): 1846. Published online 2023 Sep 23. doi: 10.3390/genes14101846

PMCID:: PMC10606254

Abstract Article PDF–1.7M

Select item 104539087.

LRP5, SLC6A3, and SOX10 Expression in Conventional Ameloblastoma

Lorena Correa-Arzate, Javier Portilla-Robertson, Josué Orlando Ramírez-Jarquín, Luis Fernando Jacinto-Alemán, Claudia Patricia Mejía-Velázquez, Francisco Germán Villanueva-Sánchez, Mariana Rodríguez-Vázquez

Genes (Basel) 2023 Aug; 14(8): 1524. Published online 2023 Jul 26. doi: 10.3390/genes14081524

PMCID:: PMC10453908

Abstract Article PDF–2.2M

Select item 101937318.

LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women

Jun Li, Zebing Liu, Yanxia Ren, Han Shao, Siyuan Li

J Orthop Surg Res. 2023; 18: 369. Published online 2023 May 18. doi: 10.1186/s13018-023-03829-y

PMCID:: PMC10193731

Abstract Article PDF–988K

Select item 101187299.

The low-density lipoprotein receptor-related protein 5 (LRP5) 4037C>T polymorphism: candidate for susceptibility to type 1 diabetes mellitus

Karla Simone Costa de Souza, Marcela Abbott Galvão Ururahy, Yonara Monique da Costa Oliveira, Melina Bezerra Loureiro, Heglayne Pereira Vital da Silva, Raul Hernandes Bortolin, André Ducati Luchessi, Ricardo Fernando Arrais, Rosário Dominguez Crespo Hirata, Maria das Graças Almeida, Mário Hiroyuki Hirata, Adriana Augusto de Rezende

Arch Endocrinol Metab. 2018 Jul-Aug; 62(4): 480–484. Published online 2018 Aug 1. doi: 10.20945/2359-3997000000057

PMCID:: PMC10118729

Abstract Article PDF–138K

Select item 926261410.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 923162311.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 921920012.

Association between the LRP5 rs556442 gene polymorphism and the risks of NAFLD and CHD in a Chinese Han population

Dongli Han, Haiying Zhang, Shousheng Liu, Likun Zhuang, Zhenzhen Zhao, Hongguang Ding, Yongning Xin

BMC Gastroenterol. 2022; 22: 305. Published online 2022 Jun 22. doi: 10.1186/s12876-022-02385-9

PMCID:: PMC9219200

Abstract Article PDF–813K

Select item 905602613.

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis

Fenglong Jiao, Clinton Yu, Andrew Wheat, Xiaorong Wang, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2022 Apr 30.

Published in final edited form as: Anal Chem. 2022 Mar 15; 94(10): 4236–4242. Published online 2022 Mar 2. doi: 10.1021/acs.analchem.1c04485

PMCID:: PMC9056026

Abstract Article PDF–1.0M

Select item 883195414.

LRP5 promotes cancer stem cell traits and chemoresistance in colorectal cancer

Xiaobo Nie, Huiyang Liu, Wenling Ye, Xiaoyun Wei, Lili Fan, Han Ma, Lanqing Li, Wanting Xue, Wenting Qi, Yan‐Dong Wang, Wei‐Dong Chen

J Cell Mol Med. 2022 Feb; 26(4): 1095–1112. Published online 2022 Jan 7. doi: 10.1111/jcmm.17164

PMCID:: PMC8831954

Abstract Article PDF–2.3M

Select item 864806415.

Ocular Features and Mutation Spectrum of Patients With Familial Exudative Vitreoretinopathy

Tianchang Tao, Ningda Xu, Jiarui Li, Hongyan Li, Jinfeng Qu, Hong Yin, Jianhong Liang, Mingwei Zhao, Xiaoxin Li, Lvzhen Huang

Invest Ophthalmol Vis Sci. 2021 Dec; 62(15): 4. Published online 2021 Dec 3. doi: 10.1167/iovs.62.15.4

PMCID:: PMC8648064

Abstract Article PDF–3.2M

Select item 864518716.

Five novel copy number variations detected in patients with familial exudative vitreoretinopathy

Jia Luo, Jing Li, Xiang Zhang, Jia-Kai Li, Hao-Jie Chen, Pei-Quan Zhao, Ping Fei

Mol Vis. 2021; 27: 632–642. Published online 2021 Nov 20.

PMCID:: PMC8645187

Abstract Article PDF–3.3M

Select item 850972217.

Identification of Rare LRP5 Variants in a Cohort of Males with Impaired Bone Mass

Maria Santa Rocca, Giovanni Minervini, Andrea Di Nisio, Maurizio Merico, Maria Bueno Marinas, Luca De Toni, Kalliopi Pilichou, Andrea Garolla, Carlo Foresta, Alberto Ferlin

Int J Mol Sci. 2021 Oct; 22(19): 10834. Published online 2021 Oct 7. doi: 10.3390/ijms221910834

PMCID:: PMC8509722

Abstract Article PDF–13M

Select item 822284818.

More severe phenotype of early‐onset osteoporosis associated with recessive form of LRP5 and combination with DKK1 or WNT3A

Caroline Caetano da Silva, Manon Ricquebourg, Philippe Orcel, Stéphanie Fabre, Thomas Funck‐Brentano, Martine Cohen‐Solal, Corinne Collet

Mol Genet Genomic Med. 2021 Jun; 9(6): e1681. Published online 2021 May 3. doi: 10.1002/mgg3.1681

PMCID:: PMC8222848

Abstract Article PDF–617K

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 791985420.

Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina

Harminder D Singh, Jian-xing Ma, Yusuke Takahashi

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Mar 19.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Mar 19; 545: 8–13. Published online 2021 Feb 3. doi: 10.1016/j.bbrc.2021.01.068

PMCID:: PMC7919854

Abstract Article PDF–982K

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