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Items: 1 to 20 of 108

1.
Proximity labeling reveals dynamic changes in the SQSTM1 protein network
Alejandro N. Rondón-Ortiz, Lushuang Zhang, Peter E.A. Ash, Avik Basu, Sambhavi Puri, Sophie J.F. van der Spek, Zihan Wang, Luke Dorrian, Andrew Emili, Benjamin Wolozin
J Biol Chem. 2024 Sep; 300(9): 107621. Published online 2024 Aug 3. doi: 10.1016/j.jbc.2024.107621
PMCID:
PMC11401034
AbstractArticlePDF–5.4M
2.
Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development
Sarai T. Dean, Chiharu Ishikawa, Xiaoqin Zhu, Sean Walulik, Timothy Nixon, Jessica K. Jordan, Samantha Henderson, Michael Wyder, Nathan Salomonis, Mark Wunderlich, Kenneth D. Greis, Daniel T. Starczynowski, Andrew G. Volk
Blood Adv. 2023 Sep 12; 7(17): 4822–4837. Published online 2023 May 22. doi: 10.1182/bloodadvances.2022009438
PMCID:
PMC10469560
AbstractArticlePDF–4.2M
3.
Cryo‐EM structure of the chain‐elongating E3 ubiquitin ligase UBR5
Zuzana Hodáková, Irina Grishkovskaya, Hanna L Brunner, Derek L Bolhuis, Katarina Belačić, Alexander Schleiffer, Harald Kotisch, Nicholas G Brown, David Haselbach
EMBO J. 2023 Aug; 42(16): e113348. Published online 2023 Jul 6. doi: 10.15252/embj.2022113348
PMCID:
PMC10425842
AbstractArticlePDF–3.0M
4.
The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia
Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy
BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4
PMCID:
PMC10080908
AbstractArticlePDF–3.2M
5.
Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor
Seung Un Seo, Seon Min Woo, Min Wook Kim, Eun-Woo Lee, Kyoung-jin Min, Taeg Kyu Kwon
Cell Death Differ. 2023 Jan; 30(1): 82–93. Published online 2022 Aug 4. doi: 10.1038/s41418-022-01047-3
PMCID:
PMC9883261
AbstractArticlePDF–4.6M
6.
Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method
Ryota Hayashida, Reika Kikuchi, Kenichiro Imai, Waka Kojima, Tatsuya Yamada, Miho Iijima, Hiromi Sesaki, Keiji Tanaka, Noriyuki Matsuda, Koji Yamano
J Biol Chem. 2023 Feb; 299(2): 102822. Published online 2022 Dec 21. doi: 10.1016/j.jbc.2022.102822
PMCID:
PMC9860496
AbstractArticlePDF–6.6M
7.
Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity
Diego Esposito, Jane Dudley-Fraser, Acely Garza-Garcia, Katrin Rittinger
Nat Commun. 2022; 13: 7583. Published online 2022 Dec 8. doi: 10.1038/s41467-022-35300-7
PMCID:
PMC9732051
AbstractArticlePDF–4.5M
8.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
9.
Structural and functional consequences of NEDD8 phosphorylation
Katrin Stuber, Tobias Schneider, Jill Werner, Michael Kovermann, Andreas Marx, Martin Scheffner
Nat Commun. 2021; 12: 5939. Published online 2021 Oct 12. doi: 10.1038/s41467-021-26189-9
PMCID:
PMC9020517
AbstractArticlePDF–2.8M
10.
Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1
Katarzyna Szymanska, Karsten Boldt, Clare V Logan, Matthew Adams, Philip A Robinson, Marius Ueffing, Elton Zeqiraj, Gabrielle Wheway, Colin A Johnson
eLife. 2022; 11: e57593. Published online 2022 Feb 16. doi: 10.7554/eLife.57593
PMCID:
PMC8880992
AbstractArticlePDF–4.6M
11.
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation
Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang
Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5
PMCID:
PMC8314547
AbstractArticlePDF–3.7M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
NEDD4 regulates ubiquitination and stability of the cell adhesion molecule IGPR-1 via lysosomal pathway
Linzi Sun, Razie Amraei, Nader Rahimi
J Biomed Sci. 2021; 28: 35. Published online 2021 May 7. doi: 10.1186/s12929-021-00731-9
PMCID:
PMC8103646
AbstractArticlePDF–1.5M
14.
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition
Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington
Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331
PMCID:
PMC8045932
AbstractArticlePDF–1.9M
15.
Comparison of cross-regulation by different OTUB1-E2 complexes
Lauren T. Que, Marie E. Morrow, Cynthia Wolberger
Biochemistry. Author manuscript; available in PMC 2021 Mar 3.
Published in final edited form as: Biochemistry. 2020 Mar 3; 59(8): 921–932. Published online 2020 Feb 24. doi: 10.1021/acs.biochem.9b00993
PMCID:
PMC7761795
AbstractArticlePDF–2.0M
16.
The E3 Ubiquitin Ligase NEDD4L Targets OGG1 for Ubiquitylation and Modulates the Cellular DNA Damage Response
Jonathan R. Hughes, Jason L. Parsons
Front Cell Dev Biol. 2020; 8: 607060. Published online 2020 Nov 12. doi: 10.3389/fcell.2020.607060
PMCID:
PMC7688902
AbstractArticlePDF–3.9M
17.
Negative regulation of NEMO signaling by the ubiquitin E3 ligase MARCH2
Kiramage Chathuranga, Tae‐Hwan Kim, Hyuncheol Lee, Jun‐Seol Park, Jae‐Hoon Kim, Wijesinghe A Gayan Chathuranga, Pathum Ekanayaka, Youn Jung Choi, Chul‐Ho Lee, Chul‐Joong Kim, Jae U Jung, Jong‐Soo Lee
EMBO J. 2020 Nov 2; 39(21): e105139. Published online 2020 Sep 16. doi: 10.15252/embj.2020105139
PMCID:
PMC7604578
AbstractArticlePDF–2.6M
18.
A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation
Jonathan Poh, Amy H. Ponsford, James Boyd, Jonathan Woodsmith, Ulrich Stelzl, Erich Wanker, Nicholas Harper, David MacEwan, Christopher M. Sanderson
Redox Biol. 2020 Oct; 37: 101686. Published online 2020 Aug 20. doi: 10.1016/j.redox.2020.101686
PMCID:
PMC7490560
AbstractArticlePDF–8.6M
19.
Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation
Bethany Mason, Susanne Flach, Felipe R. Teixeira, Raquel Manzano Garcia, Oscar M. Rueda, Jean E. Abraham, Carlos Caldas, Paul A. W. Edwards, Heike Laman
Cell Mol Life Sci. 2020 Jul; 77(13): 2605–2620. Published online 2019 Sep 27. doi: 10.1007/s00018-019-03306-y
PMCID:
PMC7320043
AbstractArticlePDF–2.5M
20.
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer
Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid, Isaac S. Harris, Bojana Jovanović, Katherine Murphy, Binbin Wang, Xintao Qiu, Jennifer E. Endress, Jaime Reyes, Klothilda Lim, Alba Font-Tello, Sudeepa Syamala, Tengfei Xiao, Chandra Sekhar Reddy Chilamakuri, Evangelia K. Papachristou, Clive D’Santos, Jayati Anand, Kunihiko Hinohara, Wei Li, Thomas O. McDonald, Adrienne Luoma, Rebecca J. Modiste, Quang-De Nguyen, Brittany Michel, Paloma Cejas, Cigall Kadoch, Jacob D. Jaffe, Kai W. Wucherpfennig, Jun Qi, X. Shirley Liu, Henry Long, Myles Brown, Jason S. Carroll, Joan S. Brugge, James Bradner, Franziska Michor, Kornelia Polyak
Mol Cell. Author manuscript; available in PMC 2021 Jun 18.
Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1096–1113.e8. Published online 2020 May 15. doi: 10.1016/j.molcel.2020.04.027
PMCID:
PMC7306005
AbstractArticlePDF–3.2M

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