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Items: 1 to 20 of 26

1.
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development
Timothy J. Mead, Sumit Bhutada, Simon J. Foulcer, Niccolò Peruzzi, Courtney M. Nelson, Deborah E. Seifert, Jonathan Larkin, Karin Tran-Lundmark, Jorge Filmus, Suneel S. Apte
Matrix Biol. Author manuscript; available in PMC 2024 Oct 31.
Published in final edited form as: Matrix Biol. 2024 Aug; 131: 1–16. Published online 2024 May 13. doi: 10.1016/j.matbio.2024.05.003
PMCID:
PMC11526477
AbstractArticlePDF–5.2M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
USP24-dependent stabilization of Runx2 recruits a p300/NCOA3 complex to transactivate ADAMTS genes and promote degeneration of intervertebral disc in chronic inflammation mice
Xingguo Li, Jun Zhang, Bing Wang, Chao Chen, Enyu Zhang, Zhengpin Lv, Qicong He, Yaoquan Hu, Xuenan Wang, Fan Zhang
Biol Direct. 2023; 18: 37. Published online 2023 Jul 6. doi: 10.1186/s13062-023-00395-5
PMCID:
PMC10324278
AbstractArticlePDF–2.7M
4.
Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis
Tayler F. L. Wishart, Frank J. Lovicu
Cells. 2023 May; 12(10): 1364. Published online 2023 May 11. doi: 10.3390/cells12101364
PMCID:
PMC10216587
AbstractArticlePDF–20M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
The Spatiotemporal Expression Pattern of Syndecans in Murine Embryonic Teeth
Jingyi Wu, Hong Li, Lu Han, Tianyu Sun, Ye Tian, Xiaofang Wang
Gene Expr Patterns. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Gene Expr Patterns. 2020 Jun; 36: 119109. Published online 2020 Mar 24. doi: 10.1016/j.gep.2020.119109
PMCID:
PMC7293924
AbstractArticlePDF–1.2M
7.
CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment
Daniel W. Hagey, Danijal Topcic, Nigel Kee, Florie Reynaud, Maria Bergsland, Thomas Perlmann, Jonas Muhr
Nat Commun. 2020; 11: 2898. Published online 2020 Jun 9. doi: 10.1038/s41467-020-16597-8
PMCID:
PMC7283355
AbstractArticlePDF–4.4M
8.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
9.
Autism-like phenotype and risk gene-RNA deadenylation by CPEB4 mis-splicing
Alberto Parras, Héctor Anta, María Santos-Galindo, Vivek Swarup, Ainara Elorza, José L. Nieto-Gonzalez, Sara Picó, Ivó H. Hernández, Juan I. Díaz-Hernández, Eulàlia Belloc, Annie Rodolosse, Neelroop N. Parikshak, Olga Peñagarikano, Rafael Fernández-Chacón, Manuel Irimia, Pilar Navarro, Daniel H. Geschwind, Raúl Méndez, José J. Lucas
Nature. Author manuscript; available in PMC 2019 Feb 15.
Published in final edited form as: Nature. 2018 Aug; 560(7719): 441–446. Published online 2018 Aug 15. doi: 10.1038/s41586-018-0423-5
PMCID:
PMC6217926
AbstractArticlePDF–5.9M
10.
Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development
P. J. E. Uijtdewilligen, E. M. Versteeg, E. M. A. van de Westerlo, J. van der Vlag, W. F. Daamen, T. H. van Kuppevelt
Biomed Res Int. 2018; 2018: 9873471. Published online 2018 Aug 29. doi: 10.1155/2018/9873471
PMCID:
PMC6136507
AbstractArticlePDF–838K
11.
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis
John P Kemp, John A Morris, Carolina Medina-Gomez, Vincenzo Forgetta, Nicole M Warrington, Scott E Youlten, Jie Zheng, Celia L Gregson, Elin Grundberg, Katerina Trajanoska, John G Logan, Andrea S Pollard, Penny C Sparkes, Elena J Ghirardello, Rebecca Allen, Victoria D Leitch, Natalie C Butterfield, Davide Komla-Ebri, Anne-Tounsia Adoum, Katharine F Curry, Jacqueline K White, Fiona Kussy, Keelin M Greenlaw, Changjiang Xu, Nicholas C Harvey, Cyrus Cooper, David J Adams, Celia MT Greenwood, Matthew T Maurano, Stephen Kaptoge, Fernando Rivadeneira, Jonathan H Tobias, Peter I Croucher, Cheryl L Ackert-Bicknell, JH Duncan Bassett, Graham R Williams, J Brent Richards, David M Evans
Nat Genet. Author manuscript; available in PMC 2018 Mar 4.
Published in final edited form as: Nat Genet. 2017 Oct; 49(10): 1468–1475. Published online 2017 Sep 4. doi: 10.1038/ng.3949
PMCID:
PMC5621629
AbstractArticlePDF–1.2M
12.
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development
Elisabeth A. Rutledge, Jean-Denis Benazet, Andrew P. McMahon
Development. 2017 Sep 1; 144(17): 3177–3188. doi: 10.1242/dev.149112
PMCID:
PMC5611955
AbstractArticle
13.
Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling
Mariana Capurro, Tomomi Izumikawa, Philippe Suarez, Wen Shi, Marzena Cydzik, Tomoyuki Kaneiwa, Jean Gariepy, Luisa Bonafe, Jorge Filmus
J Cell Biol. 2017 Sep 4; 216(9): 2911–2926. doi: 10.1083/jcb.201605119
PMCID:
PMC5584141
AbstractArticlePDF–2.5M
14.
Relatively frequent switching of transcription start sites during cerebellar development
Peter Zhang, Emmanuel Dimont, Thomas Ha, Douglas J. Swanson, the FANTOM Consortium, Winston Hide, Dan Goldowitz
BMC Genomics. 2017; 18: 461. Published online 2017 Jun 13. doi: 10.1186/s12864-017-3834-z
Correction in:
BMC Genomics. 2018; 19: 39.
PMCID:
PMC5470264
AbstractArticlePDF–2.0M
15.
Tissue-Specific Gain of RTK Signalling Uncovers Selective Cell Vulnerability during Embryogenesis
Yannan Fan, Sylvie Richelme, Emilie Avazeri, Stéphane Audebert, Françoise Helmbacher, Rosanna Dono, Flavio Maina
PLoS Genet. 2015 Sep; 11(9): e1005533. Published online 2015 Sep 22. doi: 10.1371/journal.pgen.1005533
PMCID:
PMC4579069
AbstractArticlePDF–24M
16.
PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission
Ji Seung Ko, Gopal Pramanik, Ji Won Um, Ji Seon Shim, Dongmin Lee, Kee Hun Kim, Gug-Young Chung, Giuseppe Condomitti, Ho Min Kim, Hyun Kim, Joris de Wit, Kang-Sik Park, Katsuhiko Tabuchi, Jaewon Ko
Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6): 1874–1879. Published online 2015 Jan 26. doi: 10.1073/pnas.1410138112
PMCID:
PMC4330736
AbstractArticlePDF–1.3M
17.
Unbiased Discovery of Glypican as a Novel Receptor for LRRTM4 in Regulating Excitatory Synapse Development
Joris de Wit, Matthew L. O’Sullivan, Jeffrey N. Savas, Giuseppe Condomitti, Max C. Caccese, Kristel M. Vennekens, John R. Yates, III, Anirvan Ghosh
Neuron. Author manuscript; available in PMC 2014 Apr 29.
Published in final edited form as: Neuron. 2013 Aug 21; 79(4): 696–711. Published online 2013 Aug 1. doi: 10.1016/j.neuron.2013.06.049
PMCID:
PMC4003527
AbstractArticlePDF–1.7M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors
Nicola J. Allen, Mariko L. Bennett, Lynette C. Foo, Gordon X. Wang, Chandrani Chakraborty, Stephen J. Smith, Ben A. Barres
Nature. Author manuscript; available in PMC 2012 Dec 21.
Published in final edited form as: Nature. 2012 Jun 21; 486(7403): 410–414. Published online 2012 May 27. doi: 10.1038/nature11059
PMCID:
PMC3383085
AbstractArticlePDF–762K
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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