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Select item 114822601.

CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides

Guillaume Gaud, Sooraj Achar, François X. P. Bourassa, John Davies, Teri Hatzihristidis, Seeyoung Choi, Taisuke Kondo, Selamawit Gossa, Jan Lee, Paul Juneau, Naomi Taylor, Christian S. Hinrichs, Dorian B. McGavern, Paul François, Grégoire Altan-Bonnet, Paul E. Love

Nat Immunol. Author manuscript; available in PMC 2024 Oct 16.

Published in final edited form as: Nat Immunol. 2023 Dec; 24(12): 2121–2134. Published online 2023 Nov 9. doi: 10.1038/s41590-023-01663-2

Correction in:: Nat Immunol. 2023 Dec 6

PMCID:: PMC11482260

Abstract Article PDF–6.1M

Select item 112017422.

CD3ζ-Mediated Signaling Protects Retinal Ganglion Cells in Glutamate Excitotoxicity of the Retina

Rui Du, Ping Wang, Ning Tian

Cells. 2024 Jun; 13(12): 1006. Published online 2024 Jun 8. doi: 10.3390/cells13121006

PMCID:: PMC11201742

Abstract Article PDF–25M

Select item 103624883.

Exercise training attenuates angiotensin II-induced cardiac fibrosis by reducing POU2F1 expression

Na Feng, Haiyi Yu, Yueshen Wang, Youyi Zhang, Han Xiao, Wei Gao

J Sport Health Sci. 2023 Jul; 12(4): 464–476. Published online 2022 Oct 29. doi: 10.1016/j.jshs.2022.10.004

PMCID:: PMC10362488

Abstract Article PDF–4.2M

Select item 103602954.

Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage specification

Jelena Perovanovic, Yifan Wu, Hosiana Abewe, Zuolian Shen, Erik P. Hughes, Jason Gertz, Mahesh B. Chandrasekharan, Dean Tantin

Sci Signal. Author manuscript; available in PMC 2023 Oct 18.

Published in final edited form as: Sci Signal. 2023 Apr 18; 16(781): eadd5750. Published online 2023 Apr 18. doi: 10.1126/scisignal.add5750

PMCID:: PMC10360295

Abstract Article PDF–3.5M

Select item 92957705.

A set point in the selection of the αβTCR T cell repertoire imposed by pre-TCR signaling strength

Elena R. Bovolenta, Eva M. García-Cuesta, Lydia Horndler, Julia Ponomarenko, Wolfgang W. Schamel, Mario Mellado, Mario Castro, David Abia, Hisse M. van Santen

Proc Natl Acad Sci U S A. 2022 May 31; 119(22): e2201907119. Published online 2022 May 26. doi: 10.1073/pnas.2201907119

PMCID:: PMC9295770

Abstract Article PDF–1.6M

Select item 92358756.

Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis

Sabrina Shameen Alam, Shruti Kumar, Marie-Claude Beauchamp, Eric Bareke, Alexia Boucher, Nadine Nzirorera, Yanchen Dong, Reinnier Padilla, Si Jing Zhang, Jacek Majewski, Loydie A. Jerome-Majewska

Dis Model Mech. 2022 Jun 1; 15(6): dmm049544. Published online 2022 Jun 23. doi: 10.1242/dmm.049544

PMCID:: PMC9235875

Abstract Article

Select item 90906997.

5-Azacytidine Suppresses the Expression of Tissue-Specific Oct-1 Isoform in Namalwa Burkitt’s Lymphoma Cell Culture

A. P. Kotnova, A. G. Stepchenko, Yu. V. Ilyin, S. G. Georgieva, E. V. Pankratova

Dokl Biochem Biophys. 2022; 503(1): 76–79. Published online 2022 May 10. doi: 10.1134/S1607672922020089

PMCID:: PMC9090699

Abstract Article PDF–401K

Select item 89954718.

Reduction of Cell Surface T-Cell Receptor by Non-Mitogenic CD3 Antibody to Mitigate Murine Lupus

Masashi Morita, Masayuki Mizui, Satoshi Masuyama, George C. Tsokos, Yoshitaka Isaka

Front Immunol. 2022; 13: 855812. Published online 2022 Mar 28. doi: 10.3389/fimmu.2022.855812

PMCID:: PMC8995471

Abstract Article PDF–4.6M

Select item 89530859.

The CD3ζ adaptor structure determines functional differences between human and mouse CD16 Fc receptor signaling

Oscar A. Aguilar, Lam-Kiu Fong, Kenichi Ishiyama, William F. DeGrado, Lewis L. Lanier

J Exp Med. 2022 May 2; 219(5): e20220022. Published online 2022 Mar 23. doi: 10.1084/jem.20220022

PMCID:: PMC8953085

Abstract Article PDF–6.1M

Select item 828535410.

LncRNA NEAT1 Promotes Inflammatory Response in Sepsis via the miR-31-5p/POU2F1 Axis

Yang Yang, Jianhua Xue, Lili Qin, Jiaxuan Zhang, Jiajia Liu, Junbo Yu

Inflammation. 2021; 44(4): 1518–1528. Published online 2021 Mar 12. doi: 10.1007/s10753-021-01436-9

PMCID:: PMC8285354

Abstract Article PDF–4.3M

Select item 807213211.

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex

Pauline Antonie Ulmke, M. Sadman Sakib, Peter Ditte, Godwin Sokpor, Cemil Kerimoglu, Linh Pham, Yuanbin Xie, Xiaoyi Mao, Joachim Rosenbusch, Ulrike Teichmann, Huu Phuc Nguyen, Andre Fischer, Gregor Eichele, Jochen F. Staiger, Tran Tuoc

Stem Cell Reports. 2021 Apr 13; 16(4): 968–984. Published online 2021 Apr 1. doi: 10.1016/j.stemcr.2021.03.008

PMCID:: PMC8072132

Abstract Article PDF–8.1M

Select item 793877012.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 767054813.

Transcription factor Oct1 protects against hematopoietic stress and promotes acute myeloid leukemia

Jillian L. Jafek, Arvind Shakya, Pei-Yi Tai, Andrea Ibarra, Heejoo Kim, Jessica Maddox, Jeffrey Chumley, Gerald J. Spangrude, Rodney R. Miles, Todd W. Kelley, Dean Tantin

Exp Hematol. Author manuscript; available in PMC 2020 Nov 17.

Published in final edited form as: Exp Hematol. 2019 Aug; 76: 38–48.e2. Published online 2019 Jul 8. doi: 10.1016/j.exphem.2019.07.002

PMCID:: PMC7670548

Abstract Article PDF–1.2M

Select item 661880714.

Impaired Spatial Memory in Mice Lacking CD3ζ Is Associated with Altered NMDA and AMPA Receptors Signaling Independent of T-Cell Deficiency

Antoine Louveau, Julie Angibaud, Fabienne Haspot, Maria Cecilia Opazo, Reynald Thinard, Virginie Thepenier, Stéphane J. Baudouin, Laurent Lescaudron, Philippe Hulin, Claudia A. Riedel, Hélène Boudin

J Neurosci. 2013 Nov 20; 33(47): 18672–18685. doi: 10.1523/JNEUROSCI.3028-13.2013

PMCID:: PMC6618807

Abstract Article PDF–2.8M

Select item 660760015.

T cell-selective deletion of Oct1 protects animals from autoimmune neuroinflammation while maintaining neurotropic pathogen response

Heejoo Kim, Laura Dickey, Colleen Stone, Jillian L. Jafek, Thomas E. Lane, Dean Tantin

J Neuroinflammation. 2019; 16: 133. Published online 2019 Jul 3. doi: 10.1186/s12974-019-1523-3

PMCID:: PMC6607600

Abstract Article PDF–3.1M

Select item 652207016.

Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy

Karina Vázquez-Arreguín, Claire Bensard, John C. Schell, Eric Swanson, Xinjian Chen, Jared Rutter, Dean Tantin

PLoS Genet. 2019 May; 15(5): e1007687. Published online 2019 May 6. doi: 10.1371/journal.pgen.1007687

PMCID:: PMC6522070

Abstract Article PDF–8.7M

Select item 634764317.

CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ

Jiao Fan, Lifeng Liu, Qingyan Liu, Yu Cui, Binwei Yao, Minghua Zhang, Yabing Gao, Yesheng Fu, Hongmiao Dai, Jingkun Pan, Ya Qiu, Cui Hua Liu, Fuchu He, Yu Wang, Lingqiang Zhang

Nat Commun. 2019; 10: 425. Published online 2019 Jan 25. doi: 10.1038/s41467-018-07895-3

Correction in:: Nat Commun. 2021; 12: 5670.

PMCID:: PMC6347643

Abstract Article PDF–3.7M

Select item 634427418.

Contribution of dorsal root ganglion octamer transcription factor 1 to neuropathic pain after peripheral nerve injury

Jingjing Yuan, Jing Wen, Shaogen Wu, Yuanyuan Mao, Kai Mo, Zhisong Li, Songxue Su, Hanwen Gu, Yanqiu Ai, Alex Bekker, Wei Zhang, Yuan-Xiang Tao

Pain. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Pain. 2019 Feb; 160(2): 375–384. doi: 10.1097/j.pain.0000000000001405

PMCID:: PMC6344274

Abstract Article PDF–1.0M

Select item 624905719.

Interleukin-17 producing γδ T cells originate from SOX13⁺ progenitors that are independent of γδTCR signaling

Nicholas A Spidale, Katelyn Sylvia, Kavitha Narayan, Bing Miu, Michela Frascoli, Heather J Melichar, Wu Zhihao, Jan Kisielow, Amy Palin, Thomas Serwold, Paul Love, Michihiro Kobayashi, Momoko Yoshimoto, Nitya Jain, Joonsoo Kang

Immunity. Author manuscript; available in PMC 2019 Nov 20.

Published in final edited form as: Immunity. 2018 Nov 20; 49(5): 857–872.e5. Published online 2018 Nov 6. doi: 10.1016/j.immuni.2018.09.010

PMCID:: PMC6249057

Abstract Article PDF–1.5M

Select item 621973420.

SOX4 controls invariant NKT cell differentiation by tuning TCR signaling

Nidhi Malhotra, Yilin Qi, Nicholas A. Spidale, Michela Frascoli, Bing Miu, Okhyun Cho, Katelyn Sylvia, Joonsoo Kang

J Exp Med. 2018 Nov 5; 215(11): 2887–2900. doi: 10.1084/jem.20172021

PMCID:: PMC6219734

Abstract Article PDF–2.7M

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