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Items: 1 to 20 of 75

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
APEX1 Nuclease and Redox Functions are Both Essential for Adult Mouse Hematopoietic Stem and Progenitor Cells
Samantha Zaunz, Jonathan De Smedt, Lukas Lauwereins, Lana Cleuren, Charlie Laffeber, Manmohan Bajaj, Joyce H. G. Lebbink, Jurgen A. Marteijn, Kim De Keersmaecker, Catherine Verfaillie
Stem Cell Rev Rep. 2023; 19(6): 2052–2072. Published online 2023 Jun 2. doi: 10.1007/s12015-023-10550-0
PMCID:
PMC10390635
AbstractArticlePDF–8.0M
3.
The Role of Annexin A1 in DNA Damage Response in Placental Cells: Impact on Gestational Diabetes Mellitus
Jusciele Brogin Moreli, Mayk Ricardo dos Santos, Iracema de Mattos Paranhos Calderon, Cristina Bichels Hebeda, Sandra Helena Poliselli Farsky, Estela Bevilacqua, Sonia Maria Oliani
Int J Mol Sci. 2023 Jun; 24(12): 10155. Published online 2023 Jun 15. doi: 10.3390/ijms241210155
PMCID:
PMC10299641
AbstractArticlePDF–11M
4.
APE2 promotes AID-dependent Somatic Hypermutation in primary B cell cultures that is suppressed by APE1
Carol E. Schrader, Travis Williams, Klaus Pechhold, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu
J Immunol. Author manuscript; available in PMC 2024 Jun 1.
Published in final edited form as: J Immunol. 2023 Jun 1; 210(11): 1804–1814. doi: 10.4049/jimmunol.2100946
PMCID:
PMC10234595
AbstractArticlePDF–1.3M
5.
A Novel Hypomorphic Apex1 Mouse Model Implicates Apurinic/Apyrimidinic Endonuclease 1 in Oxidative DNA Damage Repair in Gastric Epithelial Cells
David Rios-Covian, Lindsay D. Butcher, Amber L. Ablack, Gerco den Hartog, Mason T. Matsubara, Hong Ly, Andrew W. Oates, Guorong Xu, Kathleen M. Fisch, Eric T. Ahrens, Shusuke Toden, Corrie C. Brown, Kenneth Kim, Dzung Le, Lars Eckmann, Bithika Dhar, Tadahide Izumi, Peter B. Ernst, Sheila E. Crowe
Antioxid Redox Signal. January 2023; 38(1-3): 183–197. Published online 2023 Jan 16. doi: 10.1089/ars.2021.0119
PMCID:
PMC10039277
AbstractArticlePDF–1.0M
6.
APE1/Ref-1 Inhibits Adipogenic Transcription Factors during Adipocyte Differentiation in 3T3-L1 Cells
Eun-Ok Lee, Hee-Kyoung Joo, Yu-Ran Lee, Sungmin Kim, Kwon-Ho Lee, Sang-Do Lee, Byeong-Hwa Jeon
Int J Mol Sci. 2023 Feb; 24(4): 3251. Published online 2023 Feb 7. doi: 10.3390/ijms24043251
PMCID:
PMC9961804
AbstractArticlePDF–1.5M
7.
m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina
Yanling Xin, Qinghai He, Huilin Liang, Ke Zhang, Jingyi Guo, Qi Zhong, Dan Chen, Jinyan Li, Yizhi Liu, Shuyi Chen
eLife. 2022; 11: e79994. Published online 2022 Dec 2. doi: 10.7554/eLife.79994
PMCID:
PMC9718531
AbstractArticlePDF–15M
8.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
9.
A DNA repair pathway can regulate transcriptional noise to promote cell fate transitions
Ravi V. Desai, Xinyue Chen, Benjamin Martin, Sonali Chaturvedi, Dong Woo Hwang, Weihan Li, Chen Yu, Sheng Ding, Matt Thomson, Robert H. Singer, Robert A. Coleman, Maike M. K. Hansen, Leor S. Weinberger
Science. Author manuscript; available in PMC 2022 Aug 20.
Published in final edited form as: Science. 2021 Aug 20; 373(6557): eabc6506. Published online 2021 Jul 22. doi: 10.1126/science.abc6506
PMCID:
PMC8667278
AbstractArticlePDF–1.8M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling
Tung-Chang Liu, Chun-Ting Lin, Kai-Cheng Chang, Kai-Wei Guo, Shuying Wang, Jhih-Wei Chu, Yu-Yuan Hsiao
Nat Commun. 2021; 12: 601. Published online 2021 Jan 27. doi: 10.1038/s41467-020-20853-2
PMCID:
PMC7841161
AbstractArticlePDF–3.5M
12.
A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis
Georgia R. Kafer, Anthony J. Cesare
Front Cell Dev Biol. 2020; 8: 416. Published online 2020 May 29. doi: 10.3389/fcell.2020.00416
PMCID:
PMC7274024
AbstractArticlePDF–1.3M
13.
PI(4,5)P2 regulates plasma cholesterol through LDL receptor lysosomal degradation
Yuanyuan Qin, Flora Ting, Mee J Kim, Jacob Strelnikov, Joseph Harmon, Feng Gao, Andrea Dose, Ba-Bie Teng, M. Amir Alipour, Zemin Yao, Rosanne Crooke, Ronald M. Krauss, Marisa W. Medina
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2020 May; 40(5): 1311–1324. Published online 2020 Mar 19. doi: 10.1161/ATVBAHA.120.314033
PMCID:
PMC7197750
AbstractArticlePDF–2.1M
14.
Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation
Jusik Kim, Keeeun Kim, Jung-soon Mo, Youngsoo Lee
Nucleic Acids Res. 2020 Apr 17; 48(7): 3678–3691. Published online 2020 Mar 3. doi: 10.1093/nar/gkaa140
PMCID:
PMC7144915
AbstractArticlePDF–22M
15.
Characterization of nuclear factors modulating the apolipoprotein D promoter during growth arrest: Implication of PARP-1, APEX-1 and ERK1/2 catalytic activities
Louis-Charles Levros, Jr., Sonia Do Carmo, Elsy Edouard, Philippe Legault, Cyndia Charfi, Eric Rassart
Biochim Biophys Acta Mol Cell Res. 2010 Sep; 1803(9): 1062–1071. Published online 2010 May 21. doi: 10.1016/j.bbamcr.2010.04.011
PMCID:
PMC7114184
AbstractArticlePDF–1.1M
16.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
17.
Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors
Lavinia C. Dumitrache, Mikio Shimada, Susanna M. Downing, Young Don Kwak, Yang Li, Jennifer L. Illuzzi, Helen R. Russell, David M. Wilson, III, Peter J. McKinnon
Proc Natl Acad Sci U S A. 2018 Dec 26; 115(52): E12285–E12294. Published online 2018 Dec 11. doi: 10.1073/pnas.1809682115
PMCID:
PMC6310806
AbstractArticlePDF–2.0M
18.
Elevation of Serum APE1/Ref-1 in Experimental Murine Myocarditis
Seon-Ah Jin, Byung-Kwan Lim, Hee Jung Seo, Sun Kyeong Kim, Kye Taek Ahn, Byeong Hwa Jeon, Jin-Ok Jeong
Int J Mol Sci. 2017 Dec; 18(12): 2664. Published online 2017 Dec 8. doi: 10.3390/ijms18122664
PMCID:
PMC5751266
AbstractArticlePDF–1.0M
19.
Mitochondrial DNA Integrity is Maintained by APE1 in Carcinogen-induced Colorectal Cancer
J Ballista-Hernández, M Martínez-Ferrer, R Velez, C Climent, M Sanchez-Vazquez, C Torres, A Rodríguez-Muñoz, S Ayala-Peña, CA Torres-Ramos
Mol Cancer Res. Author manuscript; available in PMC 2018 Jul 1.
Published in final edited form as: Mol Cancer Res. 2017 Jul; 15(7): 831–841. Published online 2017 Mar 30. doi: 10.1158/1541-7786.MCR-16-0218
PMCID:
PMC5500394
AbstractArticlePDF–808K
20.
Nuclear complex of glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I protect smooth muscle cells against oxidant-induced cell death
Xuwei Hou, Patricia Snarski, Yusuke Higashi, Tadashi Yoshida, Alexander Jurkevich, Patrick Delafontaine, Sergiy Sukhanov
FASEB J. 2017 Jul; 31(7): 3179–3192. Published online 2017 Apr 12. doi: 10.1096/fj.201601082R
PMCID:
PMC5471514
AbstractArticle

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