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Items: 1 to 20 of 38

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Neuregulin 4 mediates the metabolic benefits of mild cold exposure by promoting beige fat thermogenesis
Zhimin Chen, Peng Zhang, Tongyu Liu, Xiaoxue Qiu, Siming Li, Jiandie D. Lin
JCI Insight. 2024 Jan 9; 9(1): e172957. Published online 2024 Jan 9. doi: 10.1172/jci.insight.172957
PMCID:
PMC10906454
AbstractArticlePDF–5.1M
3.
Deletion of Endogenous Neuregulin-4 Limits Adaptive Immunity During Interleukin-10 Receptor–Neutralizing Colitis
Jessica K Bernard, Edie B Bucar, Cambrian Y Liu, Kay Katada, Mary K Washington, Michael A Schumacher, Mark R Frey
Inflamm Bowel Dis. 2023 Nov; 29(11): 1778–1792. Published online 2023 Jun 2. doi: 10.1093/ibd/izad092
PMCID:
PMC10628918
AbstractArticlePDF–27M
4.
Neuregulin4 Acts on Hypothalamic ErBb4 to Excite Oxytocin Neurons and Preserve Metabolic Homeostasis
Yi Zhang, Yangyang Zhu, Jinghui Wang, Li Jin, Mingwei Guo, Liwei Chen, Lina Zhang, Yangyang Li, Baocheng Wan, Rong Zhang, Weiping Jia, Cheng Hu
Adv Sci (Weinh) 2023 Jun; 10(16): 2204824. Published online 2023 Apr 14. doi: 10.1002/advs.202204824
PMCID:
PMC10238187
AbstractArticlePDF–5.5M
5.
Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain
Xuying Zhang, Guanxi Xiao, Caroline Johnson, Yuheng Cai, Zachary K. Horowitz, Christine Mennicke, Robert Coffey, Mansoor Haider, David Threadgill, Rebecca Eliscu, Michael C. Oldham, Alon Greenbaum, H. Troy Ghashghaei
iScience. 2023 Mar 17; 26(3): 106242. Published online 2023 Feb 20. doi: 10.1016/j.isci.2023.106242
PMCID:
PMC10006693
AbstractArticlePDF–7.6M
6.
Brown adipose tissue-derived Nrg4 alleviates endothelial inflammation and atherosclerosis in male mice
Lingfeng Shi, Yixiang Li, Xiaoli Xu, Yangyang Cheng, Biying Meng, Jinling Xu, Lin Xiang, Jiajia Zhang, Kaiyue He, Jiayue Tong, Junxia Zhang, Lingwei Xiang, Guangda Xiang
Nat Metab. 2022; 4(11): 1573–1590. Published online 2022 Nov 18. doi: 10.1038/s42255-022-00671-0
Correction in:
Nat Metab. 2023; 5(1): 182.
PMCID:
PMC9684073
AbstractArticlePDF–22M
7.
Neuregulin-4 attenuates diabetic cardiomyopathy by regulating autophagy via the AMPK/mTOR signalling pathway
Hongchao Wang, Lijie Wang, Fuli Hu, Pengfei Wang, Yanan Xie, Fang Li, Bingyan Guo
Cardiovasc Diabetol. 2022; 21: 205. Published online 2022 Oct 11. doi: 10.1186/s12933-022-01643-0
PMCID:
PMC9554973
AbstractArticlePDF–18M
8.
Neuregulin 4 suppresses NASH-HCC development by restraining tumor-prone liver microenvironment
Peng Zhang, Zhimin Chen, Henry Kuang, Tongyu Liu, Jiaqiang Zhu, Linkang Zhou, Qiuyu Wang, Xuelian Xiong, Ziyi Meng, Xiaoxue Qiu, Ramiah Jacks, Lu Liu, Siming Li, Carey N. Lumeng, Qing Li, Xiang Zhou, Jiandie D. Lin
Cell Metab. Author manuscript; available in PMC 2023 Sep 6.
Published in final edited form as: Cell Metab. 2022 Sep 6; 34(9): 1359–1376.e7. Published online 2022 Aug 15. doi: 10.1016/j.cmet.2022.07.010
PMCID:
PMC9458631
AbstractArticlePDF–2.9M
9.
Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles
Francisco Díaz-Sáez, Carla Blanco-Sinfreu, Adrià Archilla-Ortega, David Sebastian, Montserrat Romero, Maria Isabel Hernández-Alvarez, Sílvia Mora, Xavier Testar, Wifredo Ricart, José Manuel Fernández-Real, José María Moreno-Navarrete, Julián Aragonés, Marta Camps, Antonio Zorzano, Anna Gumà
Int J Mol Sci. 2021 Dec; 22(23): 12960. Published online 2021 Nov 30. doi: 10.3390/ijms222312960
PMCID:
PMC8657571
AbstractArticlePDF–5.4M
10.
NRG4-ErbB4 signaling represses proinflammatory macrophage activity
Michael A. Schumacher, Isabella C. Dennis, Cambrian Y. Liu, Cache Robinson, Judie Shang, Jessica K. Bernard, M. Kay Washington, D. Brent Polk, Mark R. Frey
Am J Physiol Gastrointest Liver Physiol. 2021 Jun 1; 320(6): G990–G1001. Published online 2021 Apr 7. doi: 10.1152/ajpgi.00296.2020
PMCID:
PMC8285586
AbstractArticle
11.
Neuregulin-4 Is Required for Maintaining Soma Size of Pyramidal Neurons in the Motor Cortex
Blanca Paramo, Sven O. Bachmann, Stéphane J. Baudouin, Isabel Martinez-Garay, Alun M. Davies
eNeuro. 2021 Jan-Feb; 8(1): ENEURO.0288-20.2021. Prepublished online 2021 Jan 25. Published online 2021 Feb 23. doi: 10.1523/ENEURO.0288-20.2021
PMCID:
PMC8114872
AbstractArticlePDF–2.7M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
Identification of a Pax6-Dependent Epidermal Growth Factor Family Signaling Source at the Lateral Edge of the Embryonic Cerebral Cortex
Stavroula Assimacopoulos, Elizabeth A. Grove, Clifton W. Ragsdale
J Neurosci. 2003 Jul 23; 23(16): 6399–6403. doi: 10.1523/JNEUROSCI.23-16-06399.2003
PMCID:
PMC6740631
AbstractArticlePDF–447K
14.
Neuregulin-4 Is Required for the Growth and Elaboration of Striatal Medium Spiny Neuron Dendrites
Blanca Paramo, Sean Wyatt, Alun M Davies
J Neuropathol Exp Neurol. 2019 Aug; 78(8): 725–734. Published online 2019 May 24. doi: 10.1093/jnen/nlz046
PMCID:
PMC6640913
AbstractArticlePDF–981K
15.
FBXO22 mediates polyubiquitination and inactivation of LKB1 to promote lung cancer cell growth
Xiao-Na Zhu, Ping He, Liang Zhang, Shuo Yang, Hui-Lin Zhang, Di Zhu, Meng-Di Liu, Yun Yu
Cell Death Dis. 2019 Jul; 10(7): 486. Published online 2019 Jun 19. doi: 10.1038/s41419-019-1732-9
PMCID:
PMC6584689
AbstractArticlePDF–1.8M
16.
An essential role for neuregulin-4 in the growth and elaboration of developing neocortical pyramidal dendrites
Blanca Paramo, Sean Wyatt, Alun M. Davies
Exp Neurol. 2018 Apr; 302: 85–92. doi: 10.1016/j.expneurol.2018.01.002
PMCID:
PMC5866123
AbstractArticlePDF–1.9M
17.
Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression
Liang Guo, Peng Zhang, Zhimin Chen, Houjun Xia, Siming Li, Yanqiao Zhang, Sune Kobberup, Weiping Zou, Jiandie D. Lin
J Clin Invest. 2017 Dec 1; 127(12): 4449–4461. Published online 2017 Nov 6. doi: 10.1172/JCI96324
PMCID:
PMC5707158
AbstractArticlePDF–13M
18.
Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders
Zhimin Chen, Guo-Xiao Wang, Sara L. Ma, Dae Young Jung, Hyekyung Ha, Tariq Altamimi, Xu-Yun Zhao, Liang Guo, Peng Zhang, Chun-Rui Hu, Ji-Xin Cheng, Gary D. Lopaschuk, Jason K. Kim, Jiandie D. Lin
Mol Metab. 2017 Aug; 6(8): 863–872. Published online 2017 Jun 21. doi: 10.1016/j.molmet.2017.03.016
PMCID:
PMC5518721
AbstractArticlePDF–1.9M
19.
Preventing High Fat Diet-induced Obesity and Improving Insulin Sensitivity through Neuregulin 4 Gene Transfer
Yongjie Ma, Mingming Gao, Dexi Liu
Sci Rep. 2016; 6: 26242. Published online 2016 May 17. doi: 10.1038/srep26242
PMCID:
PMC4869101
AbstractArticlePDF–2.0M
20.
SCFFbxo22-KDM4A targets methylated p53 for degradation and regulates senescence
Yoshikazu Johmura, Jia Sun, Kyoko Kitagawa, Keiko Nakanishi, Toshiya Kuno, Aya Naiki-Ito, Yumi Sawada, Tomomi Miyamoto, Atsushi Okabe, Hiroyuki Aburatani, ShengFan Li, Ichiro Miyoshi, Satoru Takahashi, Masatoshi Kitagawa, Makoto Nakanishi
Nat Commun. 2016; 7: 10574. Published online 2016 Feb 12. doi: 10.1038/ncomms10574
PMCID:
PMC4754341
AbstractArticlePDF–2.8M

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