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Select item 88637731.

The deubiquitinase Usp27x as a novel regulator of cFLIP_L protein expression and sensitizer to death-receptor-induced apoptosis

Manuel Nico Dold, Xiulin Ng, Claudia Alber, Ian Edward Gentle, Georg Häcker, Arnim Weber

Apoptosis. 2022; 27(1-2): 112–132. Published online 2022 Jan 19. doi: 10.1007/s10495-021-01706-9

PMCID:: PMC8863773

Abstract Article PDF–2.7M

Select item 87690722.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 86834783.

RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding

Xiaofan Feng, Tianyi Jiang, Chun Yang, Shujie Pang, Zhiwen Ding, Heping Hu, Hui Wang, Liwei Dong, Ning Yang

Cell Death Dis. 2022 Jan; 13(1): 6. Published online 2021 Dec 17. doi: 10.1038/s41419-021-04447-4

PMCID:: PMC8683478

Abstract Article PDF–5.6M

Select item 83071944.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 75009385.

Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases

Chatrin Chatrin, Mads Gabrielsen, Lori Buetow, Mark A. Nakasone, Syed F. Ahmed, David Sumpton, Gary J. Sibbet, Brian O. Smith, Danny T. Huang

Sci Adv. 2020 Sep; 6(38): eabc0418. Published online 2020 Sep 18. doi: 10.1126/sciadv.abc0418

PMCID:: PMC7500938

Abstract Article PDF–3.4M

Select item 74710536.

Effect of genetic variation in Notch regulator DTX1 on SCLC prognosis compared with the effect on NSCLC prongosis

Seung Soo Yoo, Jang Hyuck Lee, Mi Jeong Hong, Jin Eun Choi, Hyo‐Gyoung Kang, Sook Kyung Do, Ji Hyun Kim, Sun Ah Baek, Sun Ha Choi, Won Kee Lee, Yong Hoon Lee, Hyewon Seo, Jaehee Lee, Shin Yup Lee, Seung Ick Cha, Chang Ho Kim, Jae Yong Park

Thorac Cancer. 2020 Sep; 11(9): 2698–2703. Published online 2020 Jul 22. doi: 10.1111/1759-7714.13566

PMCID:: PMC7471053

Abstract Article PDF–589K

Select item 74424747.

DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination

Syed Feroj Ahmed, Lori Buetow, Mads Gabrielsen, Sergio Lilla, Chatrin Chatrin, Gary J. Sibbet, Sara Zanivan, Danny T. Huang

Sci Adv. 2020 Aug; 6(34): eabc0629. Published online 2020 Aug 21. doi: 10.1126/sciadv.abc0629

PMCID:: PMC7442474

Abstract Article PDF–2.4M

Select item 73220678.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 71699839.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 705656710.

ARRB1-promoted NOTCH1 degradation is suppressed by oncomiR miR-223 in T cell acute lymphoblastic leukemia

Yi Shu, Yi Wang, Wen-Qiong Lv, Dan-Yi Peng, Juan Li, Hang Zhang, Guang-Jie Jiang, Bi-Jie Yang, Shan Liu, Jia Zhang, Yan-Hua Chen, Shi Tang, Ke-Xing Wan, Jun-Tao Yuan, Wei Guo, Guo Fu, Xin-Kun Qi, Zhi-Dai Liu, Hai-Yan Liu, Chao Yang, Ling-Huan Zhang, Fang-Jie Liu, Jie Yu, Peng-Hui Zhang, Bin Qu, Hui Zhao, Tong-Chuan He, Lin Zou

Cancer Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Cancer Res. 2020 Mar 1; 80(5): 988–998. Published online 2019 Dec 10. doi: 10.1158/0008-5472.CAN-19-1471

PMCID:: PMC7056567

Abstract Article PDF–2.1M

Select item 583467511.

PI5P4Kγ functions in DTX1-mediated Notch signaling

Li Zheng, Sean D. Conner

Proc Natl Acad Sci U S A. 2018 Feb 27; 115(9): E1983–E1990. Published online 2018 Feb 12. doi: 10.1073/pnas.1712142115

PMCID:: PMC5834675

Abstract Article PDF–2.4M

Select item 583340212.

c-FLIP is a target of the E3 ligase deltex1 in gastric cancer

Tzu-Sheng Hsu, Shu-Ting Mo, Ping-Ning Hsu, Ming-Zong Lai

Cell Death Dis. 2018 Feb; 9(2): 135. Published online 2018 Jan 26. doi: 10.1038/s41419-017-0165-6

PMCID:: PMC5833402

Abstract Article PDF–1.9M

Select item 547762313.

Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma

Leo Meriranta, Annika Pasanen, Riku Louhimo, Alejandra Cervera, Amjad Alkodsi, Matias Autio, Minna Taskinen, Ville Rantanen, Marja-Liisa Karjalainen-Lindsberg, Harald Holte, Jan Delabie, Rainer Lehtonen, Sampsa Hautaniemi, Sirpa Leppä

Haematologica. 2017 May; 102(5): e195–e198. doi: 10.3324/haematol.2016.157495

PMCID:: PMC5477623

Article PDF–562K

Select item 536249014.

Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC

Daria A. Gaykalova, Veronika Zizkova, Theresa Guo, Ilse Tiscareno, Yingying Wei, Rajita Vatapalli, Patrick T. Hennessey, Julie Ahn, Ludmila Danilova, Zubair Khan, Justin A. Bishop, J. Silvio Gutkind, Wayne M. Koch, William H. Westra, Elana J. Fertig, Michael F. Ochs, Joseph A. Califano

Oncotarget. 2017 Feb 28; 8(9): 15349–15363. Published online 2017 Jan 27. doi: 10.18632/oncotarget.14856

PMCID:: PMC5362490

Abstract Article PDF–1.5M

Select item 476067415.

Deltex1 Polymorphisms Are Associated with Hepatitis B Vaccination Non-Response in Southwest China

Bin Xie, Penghui Zhang, Menggang Liu, Wei Zeng, Juntao Yang, Hongming Liu

PLoS One. 2016; 11(2): e0149199. Published online 2016 Feb 19. doi: 10.1371/journal.pone.0149199

PMCID:: PMC4760674

Abstract Article PDF–631K

Select item 359434816.

New partner proteins containing novel internal recognition motif for human Glutaminase Interacting Protein (hGIP)

Sevil Zencir, Monimoy Banerjee, Melanie J. Dobson, Ferhan Ayaydin, Elfrieda Ayaydin Fodor, Zeki Topcu, Smita Mohanty

Biochem Biophys Res Commun. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Biochem Biophys Res Commun. 2013 Mar 1; 432(1): 10–15. Published online 2013 Feb 5. doi: 10.1016/j.bbrc.2013.01.098

PMCID:: PMC3594348

Abstract Article PDF–1.3M

Select item 334973417.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695

PMCID:: PMC3349734

Abstract Article PDF–377K

Select item 326170818.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 299070020.

The Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation

Julien Moretti, Patricia Chastagner, Stefano Gastaldello, Sara F. Heuss, Annette M. Dirac, René Bernards, Maria G. Masucci, Alain Israël, Christel Brou

PLoS Biol. 2010 Nov; 8(11): e1000545. Published online 2010 Nov 23. doi: 10.1371/journal.pbio.1000545

PMCID:: PMC2990700

Abstract Article PDF–1.4M

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