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Items: 1 to 20 of 54

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
GIRK2 potassium channels expressed by the AgRP neurons decrease adiposity and body weight in mice
Youjin Oh, Eun-Seon Yoo, Sang Hyeon Ju, Eunha Kim, Seulgi Lee, Seyun Kim, Kevin Wickman, Jong-Woo Sohn
PLoS Biol. 2023 Aug; 21(8): e3002252. Published online 2023 Aug 18. doi: 10.1371/journal.pbio.3002252
PMCID:
PMC10468093
AbstractArticlePDF–3.3M
4.
Suppression of pyramidal neuron G protein-gated inwardly rectifying K+ channel signaling impairs prelimbic cortical function and underlies stress-induced deficits in cognitive flexibility in male, but not female, mice
Eden M. Anderson, Steven Loke, Benjamin Wrucke, Annabel Engelhardt, Skyler Demis, Kevin O’Reilly, Evan Hess, Kevin Wickman, Matthew C. Hearing
Neuropsychopharmacology. 2021 Nov; 46(12): 2158–2169. Published online 2021 Jun 23. doi: 10.1038/s41386-021-01063-w
PMCID:
PMC8505646
AbstractArticlePDF–3.0M
5.
G-Protein-Gated Inwardly Rectifying Potassium (Kir3/GIRK) Channels Govern Synaptic Plasticity That Supports Hippocampal-Dependent Cognitive Functions in Male Mice
Souhail Djebari, Guillermo Iborra-Lázaro, Sara Temprano-Carazo, Irene Sánchez-Rodríguez, Mauricio O. Nava-Mesa, Alejandro Múnera, Agnès Gruart, José M. Delgado-García, Lydia Jiménez-Díaz, Juan D. Navarro-López
J Neurosci. 2021 Aug 18; 41(33): 7086–7102. doi: 10.1523/JNEUROSCI.2849-20.2021
PMCID:
PMC8372024
AbstractArticlePDF–5.4M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Bidirectional Influence of Limbic GIRK Channel Activation on Innate Avoidance Behavior
Baovi N. Vo, Ezequiel Marron Fernandez de Velasco, Timothy R. Rose, Hannah Oberle, Haichang Luo, Corey R. Hopkins, Kevin Wickman
J Neurosci. 2021 Jul 7; 41(27): 5809–5821. doi: 10.1523/JNEUROSCI.2787-20.2021
PMCID:
PMC8265807
AbstractArticlePDF–3.7M
8.
The Role of Parvalbumin Interneuron GIRK Signaling in the Regulation of Affect and Cognition in Male and Female Mice
Eden M. Anderson, Skyler Demis, Hunter D’Acquisto, Annabel Engelhardt, Matthew Hearing
Front Behav Neurosci. 2021; 15: 621751. Published online 2021 Mar 26. doi: 10.3389/fnbeh.2021.621751
PMCID:
PMC8032990
AbstractArticlePDF–5.8M
9.
Impact of Acute and Persistent Excitation of Prelimbic Pyramidal Neurons on Motor Activity and Trace Fear Learning
Timothy R. Rose, Ezequiel Marron Fernandez de Velasco, Baovi N. Vo, Megan E. Tipps, Kevin Wickman
J Neurosci. 2021 Feb 3; 41(5): 960–971. doi: 10.1523/JNEUROSCI.2606-20.2020
PMCID:
PMC7880283
AbstractArticlePDF–2.3M
10.
GATA6 is a regulator of sinus node development and heart rhythm
Lara Gharibeh, Abir Yamak, Jamieson Whitcomb, Aizhu Lu, Mathieu Joyal, Hiba Komati, Wenbin Liang, Céline Fiset, Mona Nemer
Proc Natl Acad Sci U S A. 2021 Jan 5; 118(1): e2007322118. Published online 2020 Dec 28. doi: 10.1073/pnas.2007322118
PMCID:
PMC7817143
AbstractArticlePDF–2.6M
11.
Genetic Loss of IK1 Causes Adrenergic-induced Phase 3 Early Afterdepolarizations and Polymorphic and Bi-directional Ventricular Tachycardia
Louise Reilly, Francisco J. Alvarado, Di Lang, Sara Abozeid, Hannah Van Ert, Cordell Spellman, Jarrett Warden, Jonathan C. Makielski, Alexey V. Glukhov, Lee L. Eckhardt
Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2020 Sep; 13(9): e008638. Published online 2020 Aug 4. doi: 10.1161/CIRCEP.120.008638
PMCID:
PMC7574954
AbstractArticlePDF–2.2M
12.
Spinal G-Protein-Gated K+ Channels Formed by GIRK1 and GIRK2 Subunits Modulate Thermal Nociception and Contribute to Morphine Analgesia
Cheryl L. Marker, Markus Stoffel, Kevin Wickman
J Neurosci. 2004 Mar 17; 24(11): 2806–2812. doi: 10.1523/JNEUROSCI.5251-03.2004
PMCID:
PMC6729517
AbstractArticlePDF–251K
13.
Molecular and Cellular Diversity of Neuronal G-Protein-Gated Potassium Channels
Lev Koyrakh, Rafael Luján, Jose Colón, Christine Karschin, Yoshihisa Kurachi, Andreas Karschin, Kevin Wickman
J Neurosci. 2005 Dec 7; 25(49): 11468–11478. doi: 10.1523/JNEUROSCI.3484-05.2005
PMCID:
PMC6725904
AbstractArticlePDF–729K
14.
Spinal G-Protein-Gated Potassium Channels Contribute in a Dose-Dependent Manner to the Analgesic Effect of μ- and δ- But Not κ-Opioids
Cheryl L. Marker, Rafael Luján, Horace H. Loh, Kevin Wickman
J Neurosci. 2005 Apr 6; 25(14): 3551–3559. doi: 10.1523/JNEUROSCI.4899-04.2005
PMCID:
PMC6725379
AbstractArticlePDF–673K
15.
Distinct Populations of Spinal Cord Lamina II Interneurons Expressing G-Protein-Gated Potassium Channels
Cheryl L. Marker, Rafael Luján, José Colón, Kevin Wickman
J Neurosci. 2006 Nov 22; 26(47): 12251–12259. doi: 10.1523/JNEUROSCI.3693-06.2006
PMCID:
PMC6675441
AbstractArticlePDF–467K
16.
Heteromultimerization of G-Protein-Gated Inwardly Rectifying K+ Channel Proteins GIRK1 and GIRK2 and Their Altered Expression in weaver Brain
Y. Joyce Liao, Yuh Nung Jan, Lily Yeh Jan
J Neurosci. 1996 Nov 15; 16(22): 7137–7150. doi: 10.1523/JNEUROSCI.16-22-07137.1996
PMCID:
PMC6578936
AbstractArticlePDF–2.0M
17.
VU0810464, a non‐urea G protein‐gated inwardly rectifying K+ (Kir3/GIRK) channel activator, exhibits enhanced selectivity for neuronal Kir3 channels and reduces stress‐induced hyperthermia in mice
Baovi N. Vo, Kristopher K. Abney, Allison Anderson, Ezequiel Marron Fernandez de Velasco, Michael A. Benneyworth, John Scott Daniels, Ryan D. Morrison, Corey R. Hopkins, Charles David Weaver, Kevin Wickman
Br J Pharmacol. 2019 Jul; 176(13): 2238–2249. Published online 2019 May 30. doi: 10.1111/bph.14671
PMCID:
PMC6555862
AbstractArticlePDF–2.3M
18.
Atrial GIRK Channels Mediate the Effects of Vagus Nerve Stimulation on Heart Rate Dynamics and Arrhythmogenesis
Steven W. Lee, Allison Anderson, Pilar A. Guzman, Atsushi Nakano, Elena G. Tolkacheva, Kevin Wickman
Front Physiol. 2018; 9: 943. Published online 2018 Jul 19. doi: 10.3389/fphys.2018.00943
PMCID:
PMC6060443
AbstractArticlePDF–2.4M
19.
Structural basis for the ethanol action on G-protein–activated inwardly rectifying potassium channel 1 revealed by NMR spectroscopy
Yuki Toyama, Hanaho Kano, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Ichio Shimada
Proc Natl Acad Sci U S A. 2018 Apr 10; 115(15): 3858–3863. Published online 2018 Mar 26. doi: 10.1073/pnas.1722257115
PMCID:
PMC5899474
AbstractArticlePDF–1.9M
20.
Expression and relevance of the G protein-gated K+ channel in the mouse ventricle
Allison Anderson, Kanchan Kulkarni, Ezequiel Marron Fernandez de Velasco, Nicholas Carlblom, Zhilian Xia, Atsushi Nakano, Kirill A. Martemyanov, Elena G. Tolkacheva, Kevin Wickman
Sci Rep. 2018; 8: 1192. Published online 2018 Jan 19. doi: 10.1038/s41598-018-19719-x
PMCID:
PMC5775354
AbstractArticlePDF–6.3M

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