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Select item 110295201.

Favorable prognostic influence of T-box transcription factor Eomesodermin in metastatic renal cell cancer patients

Anastasia Dielmann, Anne Letsch, Anika Nonnenmacher, Kurt Miller, Ulrich Keilholz, Antonia Busse

Cancer Immunol Immunother. 2016 Feb; 65(2): 181–192. Published online 2016 Jan 11. doi: 10.1007/s00262-015-1786-1

PMCID:: PMC11029520

Abstract Article PDF–1.2M

Select item 107729202.

Eomes-dependent mitochondrial regulation promotes survival of pathogenic CD4⁺ T cells during inflammation

Emeline Joulia, Michaël F. Michieletto, Arantxa Agesta, Cindy Peillex, Virginie Girault, Anne-Louise Le Dorze, Romain Peroceschi, Florence Bucciarelli, Marion Szelechowski, Adeline Chaubet, Nawad Hakim, Rémi Marrocco, Emeline Lhuillier, Manuel Lebeurrier, Rafael J. Argüello, Abdelhadi Saoudi, Hicham El Costa, Veronique Adoue, Thierry Walzer, Jean-Emmanuel Sarry, Anne S. Dejean

J Exp Med. 2024 Feb 5; 221(2): e20230449. Published online 2024 Jan 8. doi: 10.1084/jem.20230449

PMCID:: PMC10772920

Abstract Article PDF–8.3M

Select item 103133753.

T-BET and EOMES sustain mature human NK cell identity and antitumor function

Pamela Wong, Jennifer A. Foltz, Lily Chang, Carly C. Neal, Tony Yao, Celia C. Cubitt, Jennifer Tran, Samantha Kersting-Schadek, Sathvik Palakurty, Natalia Jaeger, David A. Russler-Germain, Nancy D. Marin, Margery Gang, Julia A. Wagner, Alice Y. Zhou, Miriam T. Jacobs, Mark Foster, Timothy Schappe, Lynne Marsala, Ethan McClain, Patrick Pence, Michelle Becker-Hapak, Bryan Fisk, Allegra A. Petti, Obi L. Griffith, Malachi Griffith, Melissa M. Berrien-Elliott, Todd A. Fehniger

J Clin Invest. 2023 Jul 3; 133(13): e162530. Published online 2023 Jul 3. doi: 10.1172/JCI162530

PMCID:: PMC10313375

Abstract Article PDF–13M

Select item 92073474.

Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition

Nils H. Wildner, Andreas Walker, Franziska Brauneck, Vanessa Ditt, Sven Peine, Samuel Huber, Friedrich Haag, Claudia Beisel, Joerg Timm, Julian Schulze zur Wiesch

Front Immunol. 2022; 13: 886646. Published online 2022 Jun 6. doi: 10.3389/fimmu.2022.886646

PMCID:: PMC9207347

Abstract Article PDF–5.2M

Select item 85509535.

EOMES is essential for antitumor activity of CD8⁺ T cells in chronic lymphocytic leukemia

Laura Llaó-Cid, Philipp M. Roessner, Vicente Chapaprieta, Selcen Öztürk, Tobias Roider, Marie Bordas, Ana Izcue, Dolors Colomer, Sascha Dietrich, Stephan Stilgenbauer, Bola Hanna, José Ignacio Martín-Subero, Martina Seiffert

Leukemia. 2021; 35(11): 3152–3162. Published online 2021 Mar 17. doi: 10.1038/s41375-021-01198-1

PMCID:: PMC8550953

Abstract Article PDF–2.1M

Select item 84978246.

T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells

Laura Kiekens, Wouter Van Loocke, Sylvie Taveirne, Sigrid Wahlen, Eva Persyn, Els Van Ammel, Zenzi De Vos, Patrick Matthys, Filip Van Nieuwerburgh, Tom Taghon, Pieter Van Vlierberghe, Bart Vandekerckhove, Georges Leclercq

Front Immunol. 2021; 12: 732511. Published online 2021 Sep 24. doi: 10.3389/fimmu.2021.732511

PMCID:: PMC8497824

Abstract Article PDF–4.2M

Select item 80090487.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 79803718.

Involvement of cytotoxic Eomes-expressing CD4⁺ T cells in secondary progressive multiple sclerosis

Ben J. E. Raveney, Wakiro Sato, Daiki Takewaki, Chenyang Zhang, Tomomi Kanazawa, Youwei Lin, Tomoko Okamoto, Manabu Araki, Yukio Kimura, Noriko Sato, Terunori Sano, Yuko Saito, Shinji Oki, Takashi Yamamura

Proc Natl Acad Sci U S A. 2021 Mar 16; 118(11): e2021818118. Published online 2021 Mar 8. doi: 10.1073/pnas.2021818118

PMCID:: PMC7980371

Abstract Article PDF–1.9M

Select item 78109319.

Down‐regulation of EOMES drives T‐cell exhaustion via abolishing EOMES‐mediated repression of inhibitory receptors of T cells in liver cancer

Hongwei He, Yong Yi, Xiaoyan Cai, Jiaxing Wang, Xiaochun Ni, Yipeng Fu, Shuangjian Qiu

J Cell Mol Med. 2021 Jan; 25(1): 161–169. Published online 2020 Dec 16. doi: 10.1111/jcmm.15898

PMCID:: PMC7810931

Abstract Article PDF–1.1M

Select item 778000610.

Eomes promotes esophageal carcinoma progression by recruiting Treg cells through the CCL20‐CCR6 pathway

Jingyao Lian, Saisai Liu, Ying Yue, Qingshan Yang, Zhen Zhang, Shengli Yang, Yi Zhang

Cancer Sci. 2021 Jan; 112(1): 144–154. Published online 2020 Nov 17. doi: 10.1111/cas.14712

PMCID:: PMC7780006

Abstract Article PDF–1.5M

Select item 757735111.

HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127

Rebecca B. Hasley, Changwan Hong, Wenqing Li, Travis Friesen, Yoriko Nakamura, Grace Y. Kim, Jung-Hyun Park, Julie A. Hixon, Scott Durum, Zonghui Hu, Michael C. Sneller, Raphael Oguariri, Tomozumi Imamichi, H. Clifford Lane, Marta Catalfamo

AIDS. Author manuscript; available in PMC 2020 Oct 21.

Published in final edited form as: AIDS. 2013 Jul 31; 27(12): 1867–1877. doi: 10.1097/QAD.0b013e3283618487

PMCID:: PMC7577351

Abstract Article PDF–1.8M

Select item 730950412.

Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch

Wen Juan Tu, Robert D. McCuaig, Abel H. Y. Tan, Kristine Hardy, Nabila Seddiki, Sayed Ali, Jane E. Dahlstrom, Elaine G. Bean, Jenny Dunn, Jade Forwood, Sofia Tsimbalyuk, Kate Smith, Desmond Yip, Laeeq Malik, Thiru Prasanna, Peter Milburn, Sudha Rao

Front Immunol. 2020; 11: 1228. Published online 2020 Jun 16. doi: 10.3389/fimmu.2020.01228

PMCID:: PMC7309504

Abstract Article PDF–3.0M

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 665662514.

Intermediate progenitors and Tbr2 in cortical development

Robert F. Hevner

J Anat. 2019 Sep; 235(3): 616–625. Published online 2019 Jan 24. doi: 10.1111/joa.12939

PMCID:: PMC6656625

Abstract Article PDF–424K

Select item 619433115.

Characterization of eomesodermin and T‐bet expression by allostimulated CD8⁺ T cells of healthy volunteers and kidney transplant patients in relation to graft outcome

A. Perez‐Gutierrez, D. M. Metes, L. Lu, S. Hariharan, A. W. Thomson, M. B. Ezzelarab

Clin Exp Immunol. 2018 Nov; 194(2): 259–272. Published online 2018 Sep 23. doi: 10.1111/cei.13162

PMCID:: PMC6194331

Abstract Article PDF–1.2M

Select item 586530816.

Variant of EOMES Associated with Increasing Risk in Chinese Patients with Relapsing-remitting Multiple Sclerosis

Sheng Chen, Juan Zhang, Qi-Bing Liu, Jing-Cong Zhuang, Lei Wu, Yong-Feng Xu, Hong-Fu Li, Zhi-Ying Wu, Bao-Gou Xiao

Chin Med J (Engl) 2018 Mar 20; 131(6): 643–647. doi: 10.4103/0366-6999.226892

PMCID:: PMC5865308

Abstract Article PDF–699K

Select item 578988517.

Cardiogenic programming of human pluripotent stem cells by dose-controlled activation of EOMES

Martin J. Pfeiffer, Roberto Quaranta, Ilaria Piccini, Jakob Fell, Jyoti Rao, Albrecht Röpke, Guiscard Seebohm, Boris Greber

Nat Commun. 2018; 9: 440. Published online 2018 Jan 30. doi: 10.1038/s41467-017-02812-6

PMCID:: PMC5789885

Abstract Article PDF–1.5M

Select item 533397018.

Eomesodermin and T-bet mark developmentally distinct human natural killer cells

Amélie Collins, Nyanza Rothman, Kang Liu, Steven L. Reiner

JCI Insight. 2017 Mar 9; 2(5): e90063. Published online 2017 Mar 9. doi: 10.1172/jci.insight.90063

PMCID:: PMC5333970

Abstract Article PDF–1.2M

Select item 511488519.

Eomes^hi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation

Antonia O. Cuff, Francis P. Robertson, Kerstin A. Stegmann, Laura J. Pallett, Mala K. Maini, Brian R. Davidson, Victoria Male

J Immunol. 2016 Dec 1; 197(11): 4283–4291. Published online 2016 Oct 21. doi: 10.4049/jimmunol.1601424

PMCID:: PMC5114885

Abstract Article PDF–1.5M

Select item 505336320.

Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin’s Lymphoma

Matthew Frampton, Miguel Inacio da Silva Filho, Peter Broderick, Hauke Thomsen, Asta Försti, Jayaram Vijayakrishnan, Rosie Cooke, Victor Enciso-Mora, Per Hoffmann, Markus M Nöthen, Amy Lloyd, Amy Holroyd, Lewin Eisele, Karl-Heinz Jöckel, Sabine Ponader, Elke Pogge von Strandmann, Tracy Lightfoot, Eve Roman, Annette Lake, Dorothy Montgomery, Ruth F Jarrett, Anthony J Swerdlow, Andreas Engert, Kari Hemminki, Richard S Houlston

Nat Commun. Author manuscript; available in PMC 2016 Oct 6.

Published in final edited form as: Nat Commun. 2013; 4: 2549. doi: 10.1038/ncomms3549

PMCID:: PMC5053363

Abstract Article PDF–1.4M

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