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Select item 112706701.

骆金光, 陶怀祥, 闻志远, 陈龙, 胡昊, 关翰

Nan Fang Yi Ke Da Xue Xue Bao. 2024 Jul 20; 44(7): 1284–1296. Chinese. doi: 10.12122/j.issn.1673-4254.2024.07.08

PMCID:: PMC11270670

Abstract Article PDF–6.8M

Select item 103986602.

C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains

Julia Jülg, Dieter Edbauer, Christian Behrends

EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895

PMCID:: PMC10398660

Abstract Article PDF–2.4M

Select item 101561753.

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman

Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035

Correction in:: Cell. 2023 May 25; 186(11): 2492.

PMCID:: PMC10156175

Abstract Article

Select item 83501964.

TAK1 Is a Novel Target in Hepatocellular Carcinoma and Contributes to Sorafenib Resistance

Shunjie Xia, Lin Ji, Liye Tao, Yu Pan, Zhongjie Lin, Zhe Wan, Haoqi Pan, Jie Zhao, Liuxin Cai, Junjie Xu, Xiujun Cai

Cell Mol Gastroenterol Hepatol. 2021; 12(3): 1121–1143. Published online 2021 May 5. doi: 10.1016/j.jcmgh.2021.04.016

PMCID:: PMC8350196

Abstract Article PDF–9.2M

Select item 82993985.

The GSK-3β-FBXL21 Axis Contributes to Circadian TCAP Degradation and Skeletal Muscle Function

Marvin Wirianto, Jiah Yang, Eunju Kim, Song Gao, Keshav Raj Paudel, Jong Min Choi, Jeehwan Choe, Gabrielle F. Gloston, Precious Ademoji, Randika Parakramaweera, Jianping Jin, Karyn A. Esser, Sung Yun Jung, Yong-Jian Geng, Hyun Kyoung Lee, Zheng Chen, Seung-Hee Yoo

Cell Rep. Author manuscript; available in PMC 2021 Jul 23.

Published in final edited form as: Cell Rep. 2020 Sep 15; 32(11): 108140. doi: 10.1016/j.celrep.2020.108140

PMCID:: PMC8299398

Abstract Article PDF–2.3M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74171957.

FBXW7 triggers degradation of KMT2D to favor growth of diffuse large B-cell lymphoma cells

Rizwan Saffie, Nan Zhou, Delphine Rolland, Özlem Önder, Venkatesha Basrur, Sydney Campbell, Kathryn E. Wellen, Kojo S.J. Elenitoba-Johnson, Brian C. Capell, Luca Busino

Cancer Res. Author manuscript; available in PMC 2021 Jun 15.

Published in final edited form as: Cancer Res. 2020 Jun 15; 80(12): 2498–2511. Published online 2020 Apr 29. doi: 10.1158/0008-5472.CAN-19-2247

PMCID:: PMC7417195

Abstract Article PDF–2.1M

Select item 71699838.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 65815749.

Cryptochromes-mediated Inhibition of the CRL4^Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism

Luca Rizzini, Daniel C. Levine, Mark Perelis, Joseph Bass, Clara B. Peek, Michele Pagano

Curr Biol. Author manuscript; available in PMC 2020 Jun 17.

Published in final edited form as: Curr Biol. 2019 Jun 17; 29(12): 1954–1962.e4. Published online 2019 May 30. doi: 10.1016/j.cub.2019.04.073

PMCID:: PMC6581574

Abstract Article PDF–1.1M

Select item 640010510.

Biallelic variants in FBXL3 cause intellectual disability, delayed motor development and short stature

Muhammad Ansar, Sohail Aziz Paracha, Alessandro Serretti, Muhammad T Sarwar, Jamshed Khan, Emmanuelle Ranza, Emilie Falconnet, Justyna Iwaszkiewicz, Sayyed Fahim Shah, Azhar Ali Qaisar, Federico A Santoni, Vincent Zoete, Andre Megarbane, Jawad Ahmed, Roberto Colombo, Periklis Makrythanasis, Stylianos E Antonarakis

Hum Mol Genet. 2019 Mar 15; 28(6): 972–979. Published online 2018 Nov 26. doi: 10.1093/hmg/ddy406

PMCID:: PMC6400105

Abstract Article PDF–3.9M

Select item 635110611.

The ULK1-FBXW5-SEC23B nexus controls autophagy

Yeon-Tae Jeong, Daniele Simoneschi, Sarah Keegan, David Melville, Natalia S Adler, Anita Saraf, Laurence Florens, Michael P Washburn, Claudio N Cavasotto, David Fenyö, Ana Maria Cuervo, Mario Rossi, Michele Pagano

eLife. 2018; 7: e42253. Published online 2018 Dec 31. doi: 10.7554/eLife.42253

PMCID:: PMC6351106

Abstract Article PDF–4.4M

Select item 571159512.

Composition and regulation of the cellular repertoire of SCF ubiquitin ligases

Justin M. Reitsma, Xing Liu, Kurt M. Reichermeier, Annie Moradian, Michael J. Sweredoski, Sonja Hess, Raymond J. Deshaies

Cell. Author manuscript; available in PMC 2018 Nov 30.

Published in final edited form as: Cell. 2017 Nov 30; 171(6): 1326–1339.e14. Published online 2017 Nov 2. doi: 10.1016/j.cell.2017.10.016

PMCID:: PMC5711595

Abstract Article PDF–2.4M

Select item 562796913.

PTEN counteracts FBXL2 to promote IP3R3– and Ca²⁺–mediated apoptosis limiting tumour growth

Shafi Kuchay, Carlotta Giorgi, Daniele Simoneschi, julia Pagan, Sonia Missiroli, Anita Saraf, Laurence Florens, Michael P. Washburn, Ana Collazo-Lorduy, Mireia Castillo-Martin, Carlos Cordon-Cardo, Said M. Sebti, Paolo Pinton, Michele Pagano

Nature. Author manuscript; available in PMC 2017 Oct 4.

Published in final edited form as: Nature. 2017 Jun 22; 546(7659): 554–558. Published online 2017 Jun 14. doi: 10.1038/nature22965

PMCID:: PMC5627969

Abstract Article PDF–1.3M

Select item 555085014.

miR-181d and c-myc-mediated inhibition of CRY2 and FBXL3 reprograms metabolism in colorectal cancer

Xiaofeng Guo, Yuekun Zhu, Xinya Hong, Mukun Zhang, Xingfeng Qiu, Zhenfa Wang, Zhongquan Qi, Xuehui Hong

Cell Death Dis. 2017 Jul; 8(7): e2958. Published online 2017 Jul 27. doi: 10.1038/cddis.2017.300

PMCID:: PMC5550850

Abstract Article PDF–3.9M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 539888816.

A Cryptochrome 2 mutation yields advanced sleep phase in humans

Arisa Hirano, Guangsen Shi, Christopher R Jones, Anna Lipzen, Len A Pennacchio, Ying Xu, William C Hallows, Thomas McMahon, Maya Yamazaki, Louis J Ptáček, Ying-Hui Fu

eLife. 2016; 5: e16695. Published online 2016 Aug 16. doi: 10.7554/eLife.16695

PMCID:: PMC5398888

Abstract Article PDF–3.5M

Select item 512385917.

CRY2 and FBXL3 cooperatively degrade c-MYC

Anne-Laure Huber, Stephanie J. Papp, Alanna B. Chan, Emma Henriksson, Sabine D. Jordan, Anna Kriebs, Madelena Nguyen, Martina Wallace, Zhizhong Li, Christian M. Metallo, Katja A. Lamia

Mol Cell. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Mol Cell. 2016 Nov 17; 64(4): 774–789. Published online 2016 Nov 10. doi: 10.1016/j.molcel.2016.10.012

PMCID:: PMC5123859

Abstract Article PDF–2.0M

Select item 509166818.

Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation

Daniel C. Scott, David Y. Rhee, David M. Duda, Ian R. Kelsall, Jennifer L. Olszewski, Joao A. Paulo, Annemieke de Jong, Huib Ovaa, Arno F. Alpi, J. Wade Harper, Brenda A. Schulman

Cell. Author manuscript; available in PMC 2017 Aug 25.

Published in final edited form as: Cell. 2016 Aug 25; 166(5): 1198–1214.e24. doi: 10.1016/j.cell.2016.07.027

PMCID:: PMC5091668

Abstract Article PDF–4.2M

Select item 464794119.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 461721120.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

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