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Items: 1 to 20 of 165

1.
Modulation of NOX2 causes obesity-mediated atrial fibrillation
Arvind Sridhar, Jaime DeSantiago, Hanna Chen, Mahmud Arif Pavel, Olivia Ly, Asia Owais, Miles Barney, Jordan Jousma, Sarath Babu Nukala, Khaled Abdelhady, Malek Massad, Lona Ernst Rizkallah, Sang-Ging Ong, Jalees Rehman, Dawood Darbar
J Clin Invest. 2024 Sep 17; 134(18): e175447. Published online 2024 Aug 15. doi: 10.1172/JCI175447
PMCID:
PMC11405042
AbstractArticlePDF–2.8M
2.
Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2
Shiyu Liang, Aijun Liu, Yezhou Liu, Fuxing Wang, Youli Zhou, Yuanzhengyang Long, Tao Wang, Zheng Liu, Ruobing Ren, Richard D. Ye
Proc Natl Acad Sci U S A. 2024 Jun 4; 121(23): e2320388121. Published online 2024 May 28. doi: 10.1073/pnas.2320388121
PMCID:
PMC11161758
AbstractArticlePDF–4.5M
3.
Activated SIRT1 contributes to DPT-induced glioma cell parthanatos by upregulation of NOX2 and NAT10
Shi-peng Liang, Xuan-zhong Wang, Mei-hua Piao, Xi Chen, Zhen-chuan Wang, Chen Li, Yu-bo Wang, Shan Lu, Chuan He, Yan-li Wang, Guang-fan Chi, Peng-fei Ge
Acta Pharmacol Sin. 2023 Oct; 44(10): 2125–2138. Published online 2023 Jun 5. doi: 10.1038/s41401-023-01109-3
PMCID:
PMC10545831
AbstractArticlePDF–5.3M
4.
Novel mutations in CYBB Gene Cause X-linked chronic Granulomatous Disease in Pakistani patients
Irum Gul, Taj Ali Khan, Noor ul Akbar, Naila Gul, Rehman Ali, Shahid Niaz Khan
Ital J Pediatr. 2023; 49: 95. Published online 2023 Aug 2. doi: 10.1186/s13052-023-01496-7
PMCID:
PMC10399011
AbstractArticlePDF–1.7M
5.
TIAM1–RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy
Renu A. Kowluru, Anjaneyulu Kowluru, Rajakrishnan Veluthakal, Ghulam Mohammad, Ismail Syed, Julia M. Santos, Manish Mishra
Diabetologia. Author manuscript; available in PMC 2023 Jul 3.
Published in final edited form as: Diabetologia. 2014 May; 57(5): 1047–1056. Published online 2014 Feb 20. doi: 10.1007/s00125-014-3194-z
PMCID:
PMC10317023
AbstractArticlePDF–1.3M
6.
NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation
I-Chang Su, Yu-Kai Su, Syahru Agung Setiawan, Vijesh Kumar Yadav, Iat-Hang Fong, Chi-Tai Yeh, Chien-Min Lin, Heng-Wei Liu
Int J Mol Sci. 2023 May; 24(9): 7706. Published online 2023 Apr 22. doi: 10.3390/ijms24097706
PMCID:
PMC10178261
AbstractArticlePDF–6.6M
7.
Crocetin antagonizes parthanatos in ischemic stroke via inhibiting NOX2 and preserving mitochondrial hexokinase-I
Hao Wu, Ying Li, Qian Zhang, Hanxun Wang, Wenyu Xiu, Pu Xu, Yujie Deng, Wanxu Huang, Dan Ohtan Wang
Cell Death Dis. 2023 Jan; 14(1): 50. Published online 2023 Jan 21. doi: 10.1038/s41419-023-05581-x
PMCID:
PMC9867762
AbstractArticlePDF–4.9M
8.
TRPC3-Nox2 Protein Complex Formation Increases the Risk of SARS-CoV-2 Spike Protein-Induced Cardiomyocyte Dysfunction through ACE2 Upregulation
Yuri Kato, Kazuhiro Nishiyama, Jae Man Lee, Yuko Ibuki, Yumiko Imai, Takamasa Noda, Noriho Kamiya, Takahiro Kusakabe, Yasunari Kanda, Motohiro Nishida
Int J Mol Sci. 2023 Jan; 24(1): 102. Published online 2022 Dec 21. doi: 10.3390/ijms24010102
PMCID:
PMC9820218
AbstractArticlePDF–1.5M
9.
NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients
Zhu Jiang, Linghe Wu, Britt van der Leeden, Albert C. van Rossum, Hans W.M. Niessen, Paul A.J. Krijnen
Int J Cardiol. 2023 Jan 1; 370: 454–462. Published online 2022 Nov 2. doi: 10.1016/j.ijcard.2022.10.172
PMCID:
PMC9625847
AbstractArticlePDF–2.2M
10.
The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias
Rosa Paolillo, Mathias Boulanger, Pierre Gâtel, Ludovic Gabellier, Marion De Toledo, Denis Tempé, Rawan Hallal, Dana Akl, Jérôme Moreaux, Hayeon Baik, Elise Gueret, Christian Recher, Jean-Emmanuel Sarry, Guillaume Cartron, Marc Piechaczyk, Guillaume Bossis
Haematologica. 2022 Nov 1; 107(11): 2562–2575. Published online 2022 Feb 17. doi: 10.3324/haematol.2021.279889
PMCID:
PMC9614539
AbstractArticlePDF–2.6M
11.
Structure of the core human NADPH oxidase NOX2
Sigrid Noreng, Naruhisa Ota, Yonglian Sun, Hoangdung Ho, Matthew Johnson, Christopher P. Arthur, Kellen Schneider, Isabelle Lehoux, Christopher W. Davies, Kyle Mortara, Kit Wong, Dhaya Seshasayee, Matthieu Masureel, Jian Payandeh, Tangsheng Yi, James T. Koerber
Nat Commun. 2022; 13: 6079. Published online 2022 Oct 14. doi: 10.1038/s41467-022-33711-0
PMCID:
PMC9568551
AbstractArticlePDF–2.6M
12.
Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22phox by thiol modification
Kei Miyano, Shuichiro Okamoto, Mizuho Kajikawa, Takuya Kiyohara, Chikage Kawai, Akira Yamauchi, Futoshi Kuribayashi
Redox Biol. 2022 Oct; 56: 102479. Published online 2022 Sep 13. doi: 10.1016/j.redox.2022.102479
PMCID:
PMC9486109
AbstractArticlePDF–19M
13.
Construction of three‐gene‐based prognostic signature and analysis of immune cells infiltration in children and young adults with B‐acute lymphoblastic leukemia
Chunli Xiang, Jie Wu, Liang Yu
Mol Genet Genomic Med. 2022 Jul; 10(7): e1964. Published online 2022 May 23. doi: 10.1002/mgg3.1964
PMCID:
PMC9266608
AbstractArticlePDF–16M
14.
Quercetin Prevents LPS-Induced Oxidative Stress and Inflammation by Modulating NOX2/ROS/NF-kB in Lung Epithelial Cells
Ok-Joo Sul, Seung Won Ra
Molecules. 2021 Nov; 26(22): 6949. Published online 2021 Nov 17. doi: 10.3390/molecules26226949
PMCID:
PMC8625571
AbstractArticlePDF–1.9M
15.
Chronic Granulomatous Disease and Myelodysplastic Syndrome in a Patient with a Novel Mutation in CYBB
Bárbara C. S. Reis, Daniela P. Cunha, Ana Paula S. Bueno, Flavia A. A. Carvalho, Juliana Dutra, Fabiana V. Mello, Maria Cecília Menks Ribeiro, Cristiane B. Milito, Elaine Sobral da Costa, Zilton Vasconcelos
Genes (Basel) 2021 Oct; 12(10): 1476. Published online 2021 Sep 23. doi: 10.3390/genes12101476
PMCID:
PMC8535487
AbstractArticlePDF–1.3M
16.
Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice
Alexandra S Mighiu, Alice Recalde, Klemen Ziberna, Ricardo Carnicer, Jakub Tomek, Gil Bub, Alison C Brewer, Sander Verheule, Ajay M Shah, Jillian N Simon, Barbara Casadei
Cardiovasc Res. 2021 Oct 1; 117(11): 2354–2364. Published online 2021 Jan 23. doi: 10.1093/cvr/cvab019
PMCID:
PMC8479801
AbstractArticlePDF–1.2M
17.
Therapeutic hypothermia augments the restorative effects of PKC-β and Nox2 inhibition on an in vitro model of human blood–brain barrier
Rais Reskiawan A. Kadir, Mansour Alwjwaj, Zoe McCarthy, Ulvi Bayraktutan
Metab Brain Dis. 2021; 36(7): 1817–1832. Published online 2021 Aug 16. doi: 10.1007/s11011-021-00810-8
PMCID:
PMC8437893
AbstractArticlePDF–2.7M
18.
Rac-dependent feedforward autoactivation of NOX2 leads to oxidative burst
Hanh My Hoang, Hope Elizabeth Johnson, Jongyun Heo
J Biol Chem. 2021 Aug; 297(2): 100982. Published online 2021 Jul 20. doi: 10.1016/j.jbc.2021.100982
PMCID:
PMC8353492
AbstractArticlePDF–2.4M
19.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
20.
Identification of Cytochrome b‐245, beta‐chain gene mutations, and clinical presentations in Iranian patients with X‐linked chronic granulomatous disease
Atefeh Heydari, Farhad Abolnezhadian, Mahnaz Sadeghi‐Shabestari, Alihossein Saberi, Ahmad Shamsizadeh, Ata A. Ghadiri, Pegah Ghandil
J Clin Lab Anal. 2021 Feb; 35(2): e23637. Published online 2020 Oct 23. doi: 10.1002/jcla.23637
PMCID:
PMC7891530
AbstractArticlePDF–1.0M

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