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Select item 115314951.

Oncogenic EML4-ALK assemblies suppress growth factor perception and modulate drug tolerance

David Gonzalez-Martinez, Lee Roth, Thomas R. Mumford, Juan Guan, Anh Le, Robert C. Doebele, Bo Huang, Asmin Tulpule, Magdalena Niewiadomska-Bugaj, Trever G. Bivona, Lukasz J. Bugaj

Nat Commun. 2024; 15: 9473. Published online 2024 Nov 2. doi: 10.1038/s41467-024-53451-7

PMCID:: PMC11531495

Abstract Article PDF–2.9M

Select item 114472562.

Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer

Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y

PMCID:: PMC11447256

Abstract Article PDF–2.8M

Select item 113735993.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 112969144.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 112399195.

Anaplastic Lymphoma Kinase signaling stabilizes SLC3A2 expression via MARCH11 to promote neuroblastoma cell growth

Wei-Yun Lai, Tzu-Po Chuang, Marcus Borenäs, Dan E. Lind, Bengt Hallberg, Ruth H. Palmer

Cell Death Differ. 2024 Jul; 31(7): 910–923. Published online 2024 Jun 10. doi: 10.1038/s41418-024-01319-0

PMCID:: PMC11239919

Abstract Article PDF–2.0M

Select item 112099356.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111597757.

Global genomic and RNA profiles for novel risk stratification of neuroblastoma

Miki Ohira, Akira Nakagawara

Cancer Sci. 2010 Nov; 101(11): 2295–2301. Published online 2010 Jul 16. doi: 10.1111/j.1349-7006.2010.01681.x

PMCID:: PMC11159775

Abstract Article PDF–540K

Select item 111596618.

Oncogenic mutations of ALK in neuroblastoma

Seishi Ogawa, Junko Takita, Masashi Sanada, Yasuhide Hayashi

Cancer Sci. 2011 Feb; 102(2): 302–308. Published online 2011 Jan 25. doi: 10.1111/j.1349-7006.2010.01825.x

PMCID:: PMC11159661

Abstract Article PDF–500K

Select item 111427689.

Mucinous epidermoid carcinoma of the lung with ALK mutation: Case report and literature review

Lijiao Yang, Yanyan Ren, Xing Yin

Medicine (Baltimore) 2024 May 31; 103(22): e38301. Published online 2024 May 31. doi: 10.1097/MD.0000000000038301

PMCID:: PMC11142768

Abstract Article PDF–461K

Select item 1110101110.

ALK upregulates POSTN and WNT signaling to drive neuroblastoma

Miller Huang, Wanqi Fang, Alvin Farrel, Linwei Li, Antonios Chronopoulos, Nicole Nasholm, Bo Cheng, Tina Zheng, Hiroyuki Yoda, Megumi J. Barata, Tania Porras, Matthew L. Miller, Qiqi Zhen, Lisa Ghiglieri, Lauren McHenry, Linyu Wang, Shahab Asgharzadeh, JinSeok Park, W. Clay Gustafson, Katherine K. Matthay, John M. Maris, William A. Weiss

Cell Rep. Author manuscript; available in PMC 2024 May 17.

Published in final edited form as: Cell Rep. 2024 Mar 26; 43(3): 113927. Published online 2024 Mar 6. doi: 10.1016/j.celrep.2024.113927

PMCID:: PMC11101011

Abstract Article PDF–2.0M

Select item 1083712611.

Targeting ALK averts ribonuclease 1-induced immunosuppression and enhances antitumor immunity in hepatocellular carcinoma

Chunxiao Liu, Chenhao Zhou, Weiya Xia, Yifan Zhou, Yufan Qiu, Jialei Weng, Qiang Zhou, Wanyong Chen, Ying-Nai Wang, Heng-Huan Lee, Shao-Chun Wang, Ming Kuang, Dihua Yu, Ning Ren, Mien-Chie Hung

Nat Commun. 2024; 15: 1009. Published online 2024 Feb 2. doi: 10.1038/s41467-024-45215-0

PMCID:: PMC10837126

Abstract Article PDF–9.0M

Select item 1065602012.

Dominant negative variants in KIF5B cause osteogenesis imperfecta via down regulation of mTOR signaling

Ronit Marom, Bo Zhang, Megan E. Washington, I-Wen Song, Lindsay C. Burrage, Vittoria C. Rossi, Ava S. Berrier, Anika Lindsey, Jacob Lesinski, Michael L. Nonet, Jian Chen, Dustin Baldridge, Gary A. Silverman, V. Reid Sutton, Jill A. Rosenfeld, Alyssa A. Tran, M. John Hicks, David R. Murdock, Hongzheng Dai, MaryAnn Weis, Shalini N. Jhangiani, Donna M. Muzny, Richard A. Gibbs, Richard Caswell, Carrie Pottinger, Deirdre Cilliers, Karen Stals, Undiagnosed Diseases Network, David Eyre, Deborah Krakow, Tim Schedl, Stephen C. Pak, Brendan H. Lee

PLoS Genet. 2023 Nov; 19(11): e1011005. Published online 2023 Nov 7. doi: 10.1371/journal.pgen.1011005

PMCID:: PMC10656020

Abstract Article PDF–3.1M

Select item 1065280813.

Identification of ALK Mutation in Neuroblastoma on the Point of Molecular Heterogeneity

Tekincan Çağrı Aktaş, Deniz Kızmazoğlu, Safiye Aktaş, Özde Elif Gökbayrak, Efe Serinan, Aylin Erol, Zekiye Altun, Hongling Yuan, Hatice Nur Olgun

Technol Cancer Res Treat. 2023; 22: 15330338231211138. Published online 2023 Nov 15. doi: 10.1177/15330338231211138

PMCID:: PMC10652808

Abstract Article PDF–284K

Select item 1064152414.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 1058162715.

Anaplastic Lymphoma Kinase Inhibitors for Therapy of Neuroblastoma in Adults

Jessica Stiefel, Brian H. Kushner, Stephen S. Roberts, Fiorella Iglesias-Cardenas, Kim Kramer, Shakeel Modak

JCO Precis Oncol. 2023; 7: e2300138. Published online 2023 Aug 10. doi: 10.1200/PO.23.00138

PMCID:: PMC10581627

Abstract Article PDF–1.1M

Select item 1050893316.

Clinicopathological and Prognostic Significance of the EML4-ALK Translocation and IGFR1, TTF1, Napsin A Expression in Patients with Lung Adenocarcinoma

Pınar Bulutay, Nalan Akyürek, Leyla Memış

Turk Patoloji Derg. 2021; 37(1): 7–17. Published online 2021 Jan 15. doi: 10.5146/tjpath.2020.01503

PMCID:: PMC10508933

Abstract Article PDF–4.8M

Select item 1048053517.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 1046961218.

High-sensitivity profiling of SARS-CoV-2 noncoding region–host protein interactome reveals the potential regulatory role of negative-sense viral RNA

Liuyiqi Jiang, Mu Xiao, Qing-Qing Liao, Luqian Zheng, Chunyan Li, Yuemei Liu, Bing Yang, Aiming Ren, Chao Jiang, Xin-Hua Feng

mSystems. 2023 Jul-Aug; 8(4): e00135-23. Published online 2023 Jun 14. doi: 10.1128/msystems.00135-23

PMCID:: PMC10469612

Abstract Article PDF–4.0M

Select item 1043665219.

Anaplastic lymphoma kinase overexpression enhances aggressive phenotypic characteristics of endometrial carcinoma

Ako Yokoi, Yusaku Nakamura, Miki Hashimura, Yasuko Oguri, Toshihide Matsumoto, Mayu Nakagawa, Yu Ishibashi, Takashi Ito, Kensuke Ohhigata, Youhei Harada, Naomi Fukagawa, Makoto Saegusa

BMC Cancer. 2023; 23: 765. Published online 2023 Aug 17. doi: 10.1186/s12885-023-11144-2

PMCID:: PMC10436652

Abstract Article PDF–11M

Select item 1039866020.

C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains

Julia Jülg, Dieter Edbauer, Christian Behrends

EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895

PMCID:: PMC10398660

Abstract Article PDF–2.4M

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