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Items: 1 to 20 of 49

1.
Super-enhancer-driven LncRNA PPARα-seRNA exacerbates glucolipid metabolism and diabetic cardiomyopathy via recruiting KDM4B
Xiaozhu Ma, Shuai Mei, Qidamugai Wuyun, Li Zhou, Ziyang Cai, Hu Ding, Jiangtao Yan
Mol Metab. 2024 Aug; 86: 101978. Published online 2024 Jun 29. doi: 10.1016/j.molmet.2024.101978
PMCID:
PMC11277359
AbstractArticlePDF–5.2M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures
Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang
Neuron. Author manuscript; available in PMC 2023 Oct 19.
Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028
PMCID:
PMC9665885
AbstractArticlePDF–4.5M
4.
Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase
Maheshi Udugama, Benjamin Vinod, F Lyn Chan, Linda Hii, Andrew Garvie, Philippe Collas, Paul Kalitsis, David Steer, Partha P Das, Pratibha Tripathi, Jeffrey R Mann, Hsiao P J Voon, Lee H Wong
Nucleic Acids Res. 2022 May 6; 50(8): 4500–4514. Published online 2022 Apr 22. doi: 10.1093/nar/gkac259
PMCID:
PMC9071403
AbstractArticlePDF–17M
5.
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice
Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao
Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931
PMCID:
PMC8333871
AbstractArticlePDF–1.4M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas
M. Udugama, L. Hii, A. Garvie, M. Cervini, B. Vinod, F.-L. Chan, P. P. Das, J. R. Mann, P. Collas, H. P. J. Voon, L. H. Wong
Nat Commun. 2021; 12: 2584. Published online 2021 May 10. doi: 10.1038/s41467-021-22543-z
PMCID:
PMC8110556
AbstractArticlePDF–5.3M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Heterozygous Variants in KDM4B Lead to Global Developmental Delay and Neuroanatomical Defects
Anna R. Duncan, Antonio Vitobello, Stephan C. Collins, Valerie E. Vancollie, Christopher J. Lelliott, Lance Rodan, Jiahai Shi, Ann R. Seman, Emanuele Agolini, Antonio Novelli, Paolo Prontera, Maria J. Guillen Sacoto, Teresa Santiago-Sim, Aurélien Trimouille, Cyril Goizet, Mathilde Nizon, Ange-Line Bruel, Christophe Philippe, Patricia E. Grant, Monica H. Wojcik, Joan Stoler, Casie A. Genetti, Marieke F. van Dooren, Saskia M. Maas, Marielle Alders, Laurence Faivre, Arthur Sorlin, Grace Yoon, Binnaz Yalcin, Pankaj B. Agrawal
Am J Hum Genet. 2020 Dec 3; 107(6): 1170–1177. Published online 2020 Nov 23. doi: 10.1016/j.ajhg.2020.11.001
PMCID:
PMC7820620
AbstractArticlePDF–1.6M
10.
Histone demethylase JMJD2B/KDM4B regulates transcriptional program via distinctive epigenetic targets and protein interactors for the maintenance of trophoblast stem cells
Kylie Hin-Man Mak, Yuk Man Lam, Ray Kit Ng
Sci Rep. 2021; 11: 884. Published online 2021 Jan 13. doi: 10.1038/s41598-020-79601-7
PMCID:
PMC7806742
AbstractArticlePDF–8.7M
11.
Histone H3K9 Demethylase JMJD2B Plays a Role in LXRα-Dependent Lipogenesis
Ji-Hyun Kim, Dae Young Jung, Hye-Ran Kim, Myeong Ho Jung
Int J Mol Sci. 2020 Nov; 21(21): 8313. Published online 2020 Nov 5. doi: 10.3390/ijms21218313
PMCID:
PMC7664202
AbstractArticlePDF–25M
12.
Enterotoxigenic Bacteroides fragilis induces the stemness in colorectal cancer via upregulating histone demethylase JMJD2B
Qian-Qian Liu, Chun-Min Li, Lin-Na Fu, Hao-Lian Wang, Juan Tan, Yun-Qian Wang, Dan-Feng Sun, Qin-Yan Gao, Ying-Xuan Chen, Jing-Yuan Fang
Gut Microbes. 2020; 12(1): 1788900. Published online 2020 Jul 20. doi: 10.1080/19490976.2020.1788900
PMCID:
PMC7524313
AbstractArticlePDF–12M
13.
The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition
Simone F. Glaser, Andreas W. Heumüller, Lukas Tombor, Patrick Hofmann, Marion Muhly-Reinholz, Ariane Fischer, Stefan Günther, Karoline E. Kokot, Hitoshi Okada, David Hassel, Sandeep Kumar, Hanjoong Jo, Reinier A. Boon, Wesley Abplanalp, David John, Jes-Niels Boeckel, Stefanie Dimmeler
Proc Natl Acad Sci U S A. 2020 Feb 25; 117(8): 4180–4187. Published online 2020 Feb 7. doi: 10.1073/pnas.1913481117
Correction in:
Proc Natl Acad Sci U S A. 2020 Apr 14; 117(15): 8657.
PMCID:
PMC7049147
AbstractArticlePDF–1.2M
14.
The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance
Karl Agger, Koutarou Nishimura, Satoru Miyagi, Jan-Erik Messling, Kasper Dindler Rasmussen, Kristian Helin
Blood. 2019 Oct 3; 134(14): 1154–1158. Prepublished online 2019 Aug 21. doi: 10.1182/blood.2019000855
PMCID:
PMC6776794
AbstractArticle
15.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
16.
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
John Arne Dahl, Inkyung Jung, Håvard Aanes, Gareth D. Greggains, Adeel Manaf, Mads Lerdrup, Guoqiang Li, Samantha Kuan, Bin Li, Ah Young Lee, Sebastian Preissl, Ingunn Jermstad, Mads Haugland Haugen, Rajikala Suganthan, Magnar Bjørås, Klaus Hansen, Knut Tomas Dalen, Peter Fedorcsak, Bing Ren, Arne Klungland
Nature. Author manuscript; available in PMC 2018 Dec 6.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 548–552. Published online 2016 Sep 14. doi: 10.1038/nature19360
PMCID:
PMC6283663
AbstractArticlePDF–4.9M
17.
Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2
Ji-Hyun Kim, Dae Young Jung, Arulkumar Nagappan, Myeong Ho Jung
Sci Rep. 2018; 8: 13734. Published online 2018 Sep 13. doi: 10.1038/s41598-018-31953-x
PMCID:
PMC6137221
AbstractArticlePDF–1.8M
18.
The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1
Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner
Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571
PMCID:
PMC6113890
AbstractArticlePDF–4.8M
19.
KDM4B protects against obesity and metabolic dysfunction
Yingduan Cheng, Quan Yuan, Laurent Vergnes, Xin Rong, Ji Youn Youn, Jiong Li, Yongxin Yu, Wei Liu, Hua Cai, Jiandie D. Lin, Peter Tontonoz, Christine Hong, Karen Reue, Cun-Yu Wang
Proc Natl Acad Sci U S A. 2018 Jun 12; 115(24): E5566–E5575. Published online 2018 May 29. doi: 10.1073/pnas.1721814115
Correction in:
Proc Natl Acad Sci U S A. 2019 Feb 5; 116(6): 2384–2385.
PMCID:
PMC6004484
AbstractArticlePDF–1.5M
20.
Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin
Takumi Matsuura, Satsuki Miyazaki, Tatsushi Miyazaki, Fumi Tashiro, Jun-ichi Miyazaki
Sci Rep. 2017; 7: 12462. Published online 2017 Sep 29. doi: 10.1038/s41598-017-12772-y
PMCID:
PMC5622089
AbstractArticlePDF–8.7M

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