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Select item 110731601.

Competitive blocking of LRP4–sclerostin binding interface strongly promotes bone anabolic functions

Svetlana Katchkovsky, Biplab Chatterjee, Chen-Viki Abramovitch-Dahan, Niv Papo, Noam Levaot

Cell Mol Life Sci. 2022 Feb; 79(2): 113. Published online 2022 Jan 31. doi: 10.1007/s00018-022-04127-2

PMCID:: PMC11073160

Abstract Article PDF–1.1M

Select item 108477462.

Calcium-binding protein 7 expressed in muscle negatively regulates age-related degeneration of neuromuscular junctions in mice

Takahiro Eguchi, Tohru Tezuka, Yuji Watanabe, Akane Inoue-Yamauchi, Hiroshi Sagara, Manabu Ozawa, Yuji Yamanashi

iScience. 2024 Feb 16; 27(2): 108997. Published online 2024 Jan 26. doi: 10.1016/j.isci.2024.108997

PMCID:: PMC10847746

Abstract Article PDF–5.7M

Select item 101194193.

Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function

Shuang Geng, Fabian Paul, Izabela Kowalczyk, Sandra Raimundo, Anje Sporbert, Tamrat Meshka Mamo, Annette Hammes

Front Cell Dev Biol. 2023; 11: 1173688. Published online 2023 Apr 7. doi: 10.3389/fcell.2023.1173688

PMCID:: PMC10119419

Abstract Article PDF–5.2M

Select item 99187364.

Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals

Rangjuan Cao, Peng Chen, Hongsheng Wang, Hongyang Jing, Hongsheng Zhang, Guanglin Xing, Bin Luo, Jinxiu Pan, Zheng Yu, Wen-Cheng Xiong, Lin Mei

Nat Commun. 2023; 14: 744. Published online 2023 Feb 10. doi: 10.1038/s41467-023-36454-8

PMCID:: PMC9918736

Abstract Article PDF–4.0M

Select item 89412125.

Counteractive and cooperative actions of muscle β-catenin and Ca_V1.1 during early neuromuscular synapse formation

Mehmet Mahsum Kaplan, Bernhard E. Flucher

iScience. 2022 Apr 15; 25(4): 104025. Published online 2022 Mar 4. doi: 10.1016/j.isci.2022.104025

PMCID:: PMC8941212

Abstract Article PDF–6.5M

Select item 87597946.

RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis

Zhiying Yue, Xin Niu, Zengjin Yuan, Qin Qin, Wenhao Jiang, Liang He, Jingduo Gao, Yi Ding, Yanxi Liu, Ziwei Xu, Zhenxi Li, Zhengfeng Yang, Rong Li, Xiwen Xue, Yankun Gao, Fei Yue, Xiang H.-F. Zhang, Guohong Hu, Yi Wang, Yi Li, Geng Chen, Stefan Siwko, Alison Gartland, Ning Wang, Jianru Xiao, Mingyao Liu, Jian Luo

J Clin Invest. 2022 Jan 18; 132(2): e144579. Published online 2022 Jan 18. doi: 10.1172/JCI144579

PMCID:: PMC8759794

Abstract Article PDF–9.4M

Select item 83698397.

Increasing LRP4 diminishes neuromuscular deficits in a mouse model of Duchenne muscular dystrophy

Tiankun Hui, Hongyang Jing, Tian Zhou, Peng Chen, Ziyang Liu, Xia Dong, Min Yan, Dongyan Ren, Suqi Zou, Shunqi Wang, Erkang Fei, Daojun Hong, Xinsheng Lai

Hum Mol Genet. 2021 Sep 1; 30(17): 1579–1590. Published online 2021 May 13. doi: 10.1093/hmg/ddab135

PMCID:: PMC8369839

Abstract Article PDF–1.5M

Select item 83132398.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 81800819.

Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway

Hongyang Jing, Peng Chen, Tiankun Hui, Zheng Yu, Jin Zhou, Erkang Fei, Shunqi Wang, Dongyan Ren, Xinsheng Lai, Baoming Li

Cell Biosci. 2021; 11: 105. Published online 2021 Jun 5. doi: 10.1186/s13578-021-00619-z

PMCID:: PMC8180081

Abstract Article PDF–3.4M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 773077311.

LRP4 LDLα repeats of astrocyte enhance dendrite arborization of the neuron

Min Yan, Amin Guo, Peng Chen, Hongyang Jing, Dongyan Ren, Yanzi Zhong, Yongqiang Wu, Erkang Fei, Xinsheng Lai, Suqi Zou, Shunqi Wang

Mol Brain. 2020; 13: 166. Published online 2020 Dec 10. doi: 10.1186/s13041-020-00708-z

PMCID:: PMC7730773

Abstract Article PDF–1.7M

Select item 768473912.

Lrp4 in hippocampal astrocytes serves as a negative feedback factor in seizures

Zheng Yu, Meiying Zhang, Bin Luo, Hongyang Jing, Yue Yu, Shunqi Wang, Shiwen Luo

Cell Biosci. 2020; 10: 135. Published online 2020 Nov 23. doi: 10.1186/s13578-020-00498-w

PMCID:: PMC7684739

Abstract Article PDF–1.0M

Select item 744979713.

The transcription factor Maz is essential for normal eye development

Olga Medina-Martinez, Meade Haller, Jill A. Rosenfeld, Marisol A. O'Neill, Dolores J. Lamb, Milan Jamrich

Dis Model Mech. 2020 Aug 1; 13(8): dmm044412. Published online 2020 Aug 18. doi: 10.1242/dmm.044412

PMCID:: PMC7449797

Abstract Article

Select item 740366114.

CTGF/CCN2 facilitates LRP4‐mediated formation of the embryonic neuromuscular junction

Bisei Ohkawara, Akinori Kobayakawa, Shunsuke Kanbara, Takako Hattori, Satoshi Kubota, Mikako Ito, Akio Masuda, Masaharu Takigawa, Karen M Lyons, Naoki Ishiguro, Kinji Ohno

EMBO Rep. 2020 Aug 5; 21(8): e48462. Published online 2020 Jun 17. doi: 10.15252/embr.201948462

PMCID:: PMC7403661

Abstract Article PDF–1.7M

Select item 734332715.

A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance

Hongsheng Zhang, Wenbing Chen, Zhibing Tan, Lei Zhang, Zhaoqi Dong, Wanpeng Cui, Kai Zhao, Hongsheng Wang, Hongyang Jing, Rangjuan Cao, Chae Kim, Jiri G. Safar, Wen-Cheng Xiong, Lin Mei

J Neurosci. 2020 Jul 8; 40(28): 5347–5361. doi: 10.1523/JNEUROSCI.0250-20.2020

PMCID:: PMC7343327

Abstract Article PDF–3.3M

Select item 681763116.

Lrp4 Mediates Bone Homeostasis and Mechanotransduction through Interaction with Sclerostin In Vivo

Whitney A. Bullock, April M. Hoggatt, Daniel J. Horan, Andrew J. Elmendorf, Amy Y. Sato, Teresita Bellido, Gabriela G. Loots, Fredrick M. Pavalko, Alexander G. Robling

iScience. 2019 Oct 25; 20: 205–215. Published online 2019 Sep 18. doi: 10.1016/j.isci.2019.09.023

PMCID:: PMC6817631

Abstract Article PDF–5.8M

Select item 665025217.

Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice

Hongsheng Zhang, Anupama Sathyamurthy, Fang Liu, Lei Li, Lei Zhang, Zhaoqi Dong, Wanpeng Cui, Xiangdong Sun, Kai Zhao, Hongsheng Wang, Hsin-Yi Henry Ho, Wen-Cheng Xiong, Lin Mei

eLife. 2019; 8: e45303. Published online 2019 Jul 3. doi: 10.7554/eLife.45303

PMCID:: PMC6650252

Abstract Article PDF–4.4M

Select item 663266518.

Damage-Induced Neuronal Endopeptidase Is Critical for Presynaptic Formation of Neuromuscular Junctions

Kenichi Nagata, Sumiko Kiryu-Seo, Mitsuyo Maeda, Kayo Yoshida, Takashi Morita, Hiroshi Kiyama

J Neurosci. 2010 May 19; 30(20): 6954–6962. doi: 10.1523/JNEUROSCI.4521-09.2010

PMCID:: PMC6632665

Abstract Article PDF–2.1M

Select item 651430219.

Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling

Youngwook Ahn, Carrie Sims, Jennifer M. Logue, Scott D. Weatherbee, Robb Krumlauf

Development. 2013 Feb 1; 140(3): 583–593. Published online 2013 Jan 4. doi: 10.1242/dev.085118

PMCID:: PMC6514302

Abstract Article

Select item 649796720.

Lrp4 expression by adipocytes and osteoblasts differentially impacts sclerostin's endocrine effects on body composition and glucose metabolism

Soohyun P. Kim, Hao Da, Zhu Li, Priyanka Kushwaha, Conor Beil, Lin Mei, Wen-Cheng Xiong, Michael J. Wolfgang, Thomas L. Clemens, Ryan C. Riddle

J Biol Chem. 2019 Apr 26; 294(17): 6899–6911. Published online 2019 Mar 6. doi: 10.1074/jbc.RA118.006769

PMCID:: PMC6497967

Abstract Article PDF–4.7M

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