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Select item 110146571.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 108842402.

Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects

Sabrina Quilez, Emilie Dumontier, Christopher Baim, Joseph Kam, Jean-François Cloutier

Front Cell Dev Biol. 2024; 12: 1256465. Published online 2024 Feb 9. doi: 10.3389/fcell.2024.1256465

PMCID:: PMC10884240

Abstract Article PDF–6.8M

Select item 108208863.

TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway

Timothy T. Nguyen, Jennyfer M. Mitchell, Michaela D. Kiel, Colin P. Kenny, Hong Li, Kenneth L. Jones, Robert A. Cornell, Trevor J. Williams, James T. Nichols, Eric Van Otterloo

Development. 2024 Jan 1; 151(1): dev202095. Published online 2024 Jan 2. doi: 10.1242/dev.202095

PMCID:: PMC10820886

Abstract Article

Select item 93828984.

Single-cell transcriptomic signatures and gene regulatory networks modulated by Wls in mammalian midline facial formation and clefts

Ran Gu, Shuwen Zhang, Subbroto Kumar Saha, Yu Ji, Kurt Reynolds, Moira McMahon, Bo Sun, Mohammad Islam, Paul A. Trainor, YiPing Chen, Ying Xu, Yang Chai, Diana Burkart-Waco, Chengji J. Zhou

Development. 2022 Jul 15; 149(14): dev200533. Published online 2022 Jul 22. doi: 10.1242/dev.200533

PMCID:: PMC9382898

Abstract Article

Select item 88150325.

Alx1 Deficient Mice Recapitulate Craniofacial Phenotype and Reveal Developmental Basis of ALX1-Related Frontonasal Dysplasia

Paul P. R. Iyyanar, Zhaoming Wu, Yu Lan, Yueh-Chiang Hu, Rulang Jiang

Front Cell Dev Biol. 2022; 10: 777887. Published online 2022 Jan 21. doi: 10.3389/fcell.2022.777887

PMCID:: PMC8815032

Abstract Article PDF–3.6M

Select item 88061836.

Differential regulation of cranial and cardiac neural crest by serum response factor and its cofactors

Colin J Dinsmore, Philippe Soriano

eLife. 2022; 11: e75106. Published online 2022 Jan 19. doi: 10.7554/eLife.75106

PMCID:: PMC8806183

Abstract Article PDF–9.5M

Select item 83132397.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 77067088.

FGF signaling regulates development by processes beyond canonical pathways

Ayan T. Ray, Pierre Mazot, J. Richard Brewer, Catarina Catela, Colin J. Dinsmore, Philippe Soriano

Genes Dev. 2020 Dec 1; 34(23-24): 1735–1752. doi: 10.1101/gad.342956.120

Correction in:: Genes Dev. 2021 May 1; 35(9-10): 783.

PMCID:: PMC7706708

Abstract Article PDF–18M

Select item 73623369.

Parenchymal and Stromal Tissue Regeneration of Tooth Organ by Pivotal Signals Reinstated in Decellularized Matrix

Ling He, Jian Zhou, Mo Chen, Chyuan-Sheng Lin, Sahng G. Kim, Yue Zhou, Lusai Xiang, Ming Xie, Hanying Bai, Hai Yao, Changcheng Shi, Paulo G. Coelho, Timothy G. Bromage, Bin Hu, Nick Tovar, Lukasz Witek, Jiaqian Wu, Kenian Chen, Wei Gu, Jinxuan Zheng, Tzong-Jen Sheu, Juan Zhong, Jin Wen, Yuting Niu, Bin Cheng, Qimei Gong, David M. Owens, Milda Stanislauskas, Jasmine Pei, Gregory Chotkowski, Sainan Wang, Guodong Yang, David J. Zegarelli, Xin Shi, Myron Finkel, Wen Zhang, Junyuan Li, Jiayi Cheng, Dennis P. Tarnow, Xuedong Zhou, Zuolin Wang, Xinquan Jiang, Alexander Romanov, David W. Rowe, Songlin Wang, Ling Ye, Junqi Ling, Jeremy J. Mao

Nat Mater. Author manuscript; available in PMC 2020 Jul 15.

Published in final edited form as: Nat Mater. 2019 Jun; 18(6): 627–637. Published online 2019 May 21. doi: 10.1038/s41563-019-0368-6

PMCID:: PMC7362336

Abstract Article PDF–1.8M

Select item 711617510.

Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach

Surangi N. Perera, Ruth M. Williams, Rachel Lyne, Oliver Stubbs, Dennis P. Buehler, Tatjana Sauka-Spengler, Masaharu Noda, Gos Micklem, E. Michelle Southard-Smith, Clare V. H. Baker

Glia. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Glia. 2020 Dec 1; 68(12): 2550–2584. Published online 2020 Aug 28. doi: 10.1002/glia.23870

PMCID:: PMC7116175

Abstract Article PDF–8.9M

Select item 661169411.

Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival

Marshall Lukacs, Tia Roberts, Praneet Chatuverdi, Rolf W Stottmann

eLife. 2019; 8: e45248. Published online 2019 Jun 24. doi: 10.7554/eLife.45248

PMCID:: PMC6611694

Abstract Article PDF–6.5M

Select item 648100712.

Crucial and Overlapping Roles of Six1 and Six2 in Craniofacial Development

Z. Liu, C. Li, J. Xu, Y. Lan, H. Liu, X. Li, P. Maire, X. Wang, R. Jiang

J Dent Res. 2019 May; 98(5): 572–579. Published online 2019 Mar 24. doi: 10.1177/0022034519835204

PMCID:: PMC6481007

Abstract Article PDF–890K

Select item 604995613.

mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development

Xuguang Nie, Jinxuan Zheng, Christopher L. Ricupero, Ling He, Kai Jiao, Jeremy J. Mao

PLoS Genet. 2018 Jul; 14(7): e1007491. Published online 2018 Jul 5. doi: 10.1371/journal.pgen.1007491

PMCID:: PMC6049956

Abstract Article PDF–69M

Select item 590616414.

Genes and MicroRNAs Associated with Mouse Cleft Palate: A Systematic Review and Bioinformatics Analysis

Akiko Suzuki, Nada Abdallah, Mona Gajera, Goo Jun, Peilin Jia, Zhongming Zhao, Junichi Iwata

Mech Dev. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Mech Dev. 2018 Apr; 150: 21–27. Published online 2018 Feb 21. doi: 10.1016/j.mod.2018.02.003

PMCID:: PMC5906164

Abstract Article PDF–472K

Select item 578541415.

PITX1 Promotes Chondrogenesis and Myogenesis in Mouse Hindlimbs Through Conserved Regulatory Targets

Jialiang S. Wang, Carlos R. Infante, Sungdae Park, Douglas B. Menke

Dev Biol. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Dev Biol. 2018 Feb 1; 434(1): 186–195. Published online 2017 Dec 20. doi: 10.1016/j.ydbio.2017.12.013

PMCID:: PMC5785414

Abstract Article PDF–1.6M

Select item 542820616.

Embryonic defence mechanisms against glucose-dependent oxidative stress require enhanced expression of Alx3 to prevent malformations during diabetic pregnancy

Patricia García-Sanz, Mercedes Mirasierra, Rosario Moratalla, Mario Vallejo

Sci Rep. 2017; 7: 389. Published online 2017 Mar 24. doi: 10.1038/s41598-017-00334-1

PMCID:: PMC5428206

Abstract Article PDF–2.0M

Select item 491660317.

Specification of jaw identity by the Hand2 transcription factor

Noriko Funato, Hiroki Kokubo, Masataka Nakamura, Hiromi Yanagisawa, Yumiko Saga

Sci Rep. 2016; 6: 28405. Published online 2016 Jun 22. doi: 10.1038/srep28405

PMCID:: PMC4916603

Abstract Article PDF–3.6M

Select item 491355118.

Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs

Juhee Jeong, Xue Li, Robert J. McEvilly, Michael G. Rosenfeld, Thomas Lufkin, John L. R. Rubenstein

Development. Author manuscript; available in PMC 2016 Jun 20.

Published in final edited form as: Development. 2008 Sep; 135(17): 2905–2916. doi: 10.1242/dev.019778

PMCID:: PMC4913551

Abstract Article PDF–1005K

Select item 474369219.

The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6^−/− shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand

Daniele Conte, Giulia Garaffo, Nadia Lo Iacono, Stefano Mantero, Stefano Piccolo, Michelangelo Cordenonsi, David Perez-Morga, Valeria Orecchia, Valeria Poli, Giorgio R. Merlo

Hum Mol Genet. 2016 Feb 15; 25(4): 740–754. Published online 2015 Dec 18. doi: 10.1093/hmg/ddv514

PMCID:: PMC4743692

Abstract Article PDF–1.2M

Select item 437446720.

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico

A. Murat Maga, Nicolas Navarro, Michael L. Cunningham, Timothy C. Cox

Front Physiol. 2015; 6: 92. Published online 2015 Mar 26. doi: 10.3389/fphys.2015.00092

PMCID:: PMC4374467

Abstract Article PDF–2.2M

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