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Select item 109464401.

Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm

Matthew P. Pappas, Hiroko Kawakami, Dylan Corcoran, Katherine Q. Chen, Earl Parker Scott, Julia Wong, Micah D. Gearhart, Ryuichi Nishinakamura, Yasushi Nakagawa, Yasuhiko Kawakami

Development. 2024 Mar 1; 151(5): dev202649. Published online 2024 Mar 4. doi: 10.1242/dev.202649

PMCID:: PMC10946440

Abstract Article

Select item 103359372.

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis

Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen, Alexander Meissner

Nat Genet. 2023; 55(7): 1176–1185. Published online 2023 Jul 6. doi: 10.1038/s41588-023-01435-6

PMCID:: PMC10335937

Abstract Article PDF–25M

Select item 100796773.

Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis

Yudai Hatakeyama, Nen Saito, Yusuke Mii, Ritsuko Takada, Takuma Shinozuka, Tatsuya Takemoto, Honda Naoki, Shinji Takada

Nat Commun. 2023; 14: 1924. Published online 2023 Apr 6. doi: 10.1038/s41467-023-37350-x

PMCID:: PMC10079677

Abstract Article PDF–12M

Select item 97718194.

Primate gastrulation and early organogenesis at single-cell resolution

Jinglei Zhai, Jing Guo, Haifeng Wan, Luqing Qi, Lizhong Liu, Zhenyu Xiao, Long Yan, Daniel A. Schmitz, Yanhong Xu, Dainan Yu, Xulun Wu, Wentao Zhao, Kunyuan Yu, Xiangxiang Jiang, Fan Guo, Jun Wu, Hongmei Wang

Nature. 2022; 612(7941): 732–738. Published online 2022 Dec 14. doi: 10.1038/s41586-022-05526-y

PMCID:: PMC9771819

Abstract Article PDF–19M

Select item 95344135.

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing

Jessica Kim, Masafumi Muraoka, Hajime Okada, Atsushi Toyoda, Rieko Ajima, Yumiko Saga

PLoS Genet. 2022 Oct; 18(10): e1009967. Published online 2022 Oct 5. doi: 10.1371/journal.pgen.1009967

PMCID:: PMC9534413

Abstract Article PDF–3.8M

Select item 94851616.

A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production

Naomi R. Genuth, Zhen Shi, Koshi Kunimoto, Victoria Hung, Adele F. Xu, Craig H. Kerr, Gerald C. Tiu, Juan A. Oses-Prieto, Rachel E. A. Salomon-Shulman, Jeffrey D. Axelrod, Alma L. Burlingame, Kyle M. Loh, Maria Barna

Nat Commun. 2022; 13: 5491. Published online 2022 Sep 19. doi: 10.1038/s41467-022-33263-3

PMCID:: PMC9485161

Abstract Article PDF–3.6M

Select item 94823347.

TMEM132A ensures mouse caudal neural tube closure and regulates integrin-based mesodermal migration

Binbin Li, Liza Brusman, Jacob Dahlka, Lee A. Niswander

Development. 2022 Sep 1; 149(17): dev200442. Published online 2022 Aug 30. doi: 10.1242/dev.200442

PMCID:: PMC9482334

Abstract Article

Select item 93821178.

A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation

Tingxu Chen, Heather Alcorn, Sujan Devbhandari, Dirk Remus, Elizabeth Lacy, Danwei Huangfu, Kathryn V. Anderson

Biol Open. 2022 Aug 15; 11(8): bio059307. Published online 2022 Aug 8. doi: 10.1242/bio.059307

PMCID:: PMC9382117

Abstract Article PDF–10M

Select item 91944829.

The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice

Tianyu Zhao, Moira McMahon, Kurt Reynolds, Subbroto Kumar Saha, Arjun Stokes, Chengji J. Zhou

Dis Model Mech. 2022 Jun 1; 15(6): dmm049517. Published online 2022 Jun 10. doi: 10.1242/dmm.049517

PMCID:: PMC9194482

Abstract Article

Select item 917902910.

Increased TBX6 Gene Dosages Induce Congenital Cervical Vertebral Malformations in Humans and Mice

Xiaojun Ren, Nan Yang, Nan Wu, Ximing Xu, Weisheng Chen, Ling Zhang, Yingping Li, Renqian Du, Shuangshuang Dong, Sen Zhao, Shuxia Chen, Li-Ping Jiang, Lianlei Wang, Jianguo Zhang, Zhihong Wu, Li Jin, Guixing Qiu, James R. Lupski, Jiangang Shi, Feng Zhang, Pengfei Liu

J Med Genet. Author manuscript; available in PMC 2022 Jun 9.

Published in final edited form as: J Med Genet. 2020 Jun; 57(6): 371–379. Published online 2019 Dec 30. doi: 10.1136/jmedgenet-2019-106333

PMCID:: PMC9179029

Abstract Article PDF–559K

Select item 839053011.

A TALE/HOX code unlocks WNT signalling response towards paraxial mesoderm

Luca Mariani, Xiaogang Guo, Niels Alvaro Menezes, Anna Maria Drozd, Selgin Deniz Çakal, Qinhu Wang, Elisabetta Ferretti

Nat Commun. 2021; 12: 5136. Published online 2021 Aug 26. doi: 10.1038/s41467-021-25370-4

PMCID:: PMC8390530

Abstract Article PDF–13M

Select item 771790412.

Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function

Matthew J Anderson, Valentin Magidson, Ryoichiro Kageyama, Mark Lewandoski

eLife. 2020; 9: e55608. Published online 2020 Nov 19. doi: 10.7554/eLife.55608

PMCID:: PMC7717904

Abstract Article PDF–6.9M

Select item 747363913.

Functionally distinct roles for T and Tbx6 during mouse development

Amy K. Wehn, Deborah R. Farkas, Carly E. Sedlock, Dibya Subedi, Deborah L. Chapman

Biol Open. 2020 Aug 15; 9(8): bio054692. Published online 2020 Aug 27. doi: 10.1242/bio.054692

PMCID:: PMC7473639

Abstract Article PDF–1.6M

Select item 739196214.

A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation

Alexander Aulehla, Winfried Wiegraebe, Valerie Baubet, Matthias B. Wahl, Chuxia Deng, Makoto Taketo, Mark Lewandoski, Olivier Pourquié

Nat Cell Biol. Author manuscript; available in PMC 2020 Jul 30.

Published in final edited form as: Nat Cell Biol. 2008 Feb; 10(2): 186–193. Published online 2007 Dec 23. doi: 10.1038/ncb1679

PMCID:: PMC7391962

Abstract Article PDF–1.6M

Select item 735493215.

Hedgehog–FGF signaling axis patterns anterior mesoderm during gastrulation

Alexander Guzzetta, Mervenaz Koska, Megan Rowton, Kaelan R. Sullivan, Jessica Jacobs-Li, Junghun Kweon, Hunter Hidalgo, Heather Eckart, Andrew D. Hoffmann, Rebecca Back, Stephanie Lozano, Anne M. Moon, Anindita Basu, Michael Bressan, Sebastian Pott, Ivan P. Moskowitz

Proc Natl Acad Sci U S A. 2020 Jul 7; 117(27): 15712–15723. Published online 2020 Jun 19. doi: 10.1073/pnas.1914167117

PMCID:: PMC7354932

Abstract Article PDF–3.0M

Select item 732415916.

A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation

André Dias, Anastasiia Lozovska, Filip J Wymeersch, Ana Nóvoa, Anahi Binagui-Casas, Daniel Sobral, Gabriel G Martins, Valerie Wilson, Moises Mallo

eLife. 2020; 9: e56615. Published online 2020 Jun 29. doi: 10.7554/eLife.56615

PMCID:: PMC7324159

Abstract Article PDF–16M

Select item 717484317.

A dorsal-ventral gradient of Wnt3a/β-catenin signals controls mouse hindgut extension and colon formation

Robert J. Garriock, Ravindra B. Chalamalasetty, JianJian Zhu, Mark W. Kennedy, Amit Kumar, Susan Mackem, Terry P. Yamaguchi

Development. 2020 Apr 15; 147(8): dev185108. Published online 2020 Apr 12. doi: 10.1242/dev.185108

PMCID:: PMC7174843

Abstract Article

Select item 711638918.

Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse

Sebastian J. Arnold, Ulf K. Hofmann, Elizabeth K. Bikoff, Elizabeth J. Robertson

Development. Author manuscript; available in PMC 2020 Nov 18.

Published in final edited form as: Development. 2008 Feb 1; 135(3): 501–11. Published online 2008 Jan 2. doi: 10.1242/dev.014357

PMCID:: PMC7116389

Abstract Article PDF–2.8M

Select item 666834319.

The copy number variation landscape of congenital anomalies of the kidney and urinary tract

Miguel Verbitsky, Rik Westland, Alejandra Perez, Krzysztof Kiryluk, Qingxue Liu, Priya Krithivasan, Adele Mitrotti, David A. Fasel, Ekaterina Batourina, Matthew G. Sampson, Monica Bodria, Max Werth, Charlly Kao, Jeremiah Martino, Valentina P. Capone, Asaf Vivante, Shirlee Shril, Byum Hee Kil, Maddalena Marasa, Jun Y. Zhang, Young-Ji Na, Tze Y. Lim, Dina Ahram, Patricia L. Weng, Erin L. Heinzen, Alba Carrea, Giorgio Piaggio, Loreto Gesualdo, Valeria Manca, Giuseppe Masnata, Maddalena Gigante, Daniele Cusi, Claudia Izzi, Francesco Scolari, Joanna A.E. van Wijk, Marijan Saraga, Domenico Santoro, Giovanni Conti, Pasquale Zamboli, Hope White, Dorota Drozdz, Katarzyna Zachwieja, Monika Miklaszewska, Marcin Tkaczyk, Daria Tomczyk, Anna Krakowska, Przemyslaw Sikora, Tomasz Jarmoliński, Maria K. Borszewska-Kornacka, Robert Pawluch, Maria Szczepanska, Piotr Adamczyk, Malgorzata Mizerska-Wasiak, Grazyna Krzemien, Agnieszka Szmigielska, Marcin Zaniew, Mark G. Dobson, John M. Darlow, Prem Puri, David E. Barton, Susan L. Furth, Bradley A. Warady, Zoran Gucev, Vladimir J. Lozanovski, Velibor Tasic, Isabella Pisani, Landino Allegri, Lida M. Rodas, Josep M. Campistol, Cécile Jeanpierre, Shumyle Alam, Pasquale Casale, Craig S. Wong, Fangming Lin, Débora M. Miranda, Eduardo A. Oliveira, Ana Cristina Simões-e-Silva, Jonathan M. Barasch, Brynn Levy, Nan Wu, Friedhelm Hildebrandt, Gian Marco Ghiggeri, Anna Latos-Bielenska, Anna Materna-Kiryluk, Feng Zhang, Hakon Hakonarson, Virginia E. Papaioannou, Cathy L. Mendelsohn, Ali G. Gharavi, Simone Sanna-Cherchi

Nat Genet. Author manuscript; available in PMC 2019 Jul 31.

Published in final edited form as: Nat Genet. 2019 Jan; 51(1): 117–127. Published online 2018 Dec 21. doi: 10.1038/s41588-018-0281-y

PMCID:: PMC6668343

Abstract Article PDF–952K

Select item 662138220.

Spatially Coordinated Kinase Signaling Regulates Local Axon Degeneration

Mark Chen, Janice A. Maloney, Dara Y. Kallop, Jasvinder K. Atwal, Stephen J. Tam, Kristin Baer, Holger Kissel, Joshua S. Kaminker, Joseph W. Lewcock, Robby M. Weimer, Ryan J. Watts

J Neurosci. 2012 Sep 26; 32(39): 13439–13453. doi: 10.1523/JNEUROSCI.2039-12.2012

PMCID:: PMC6621382

Abstract Article PDF–5.3M

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