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Select item 109296641.

Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer

Min-Sik Lee, Courtney Dennis, Insia Naqvi, Lucas Dailey, Alireza Lorzadeh, George Ye, Tamara Zaytouni, Ashley Adler, Daniel S. Hitchcock, Lin Lin, Megan T. Hoffman, Aladdin M. Bhuiyan, Jaimie L. Barth, Miranda E. Machacek, Mari Mino-Kenudson, Stephanie K Dougan, Unmesh Jadhav, Clary B. Clish, Nada Y. Kalaany

Nature. Author manuscript; available in PMC 2024 Mar 12.

Published in final edited form as: Nature. 2023 Apr; 616(7956): 339–347. Published online 2023 Mar 29. doi: 10.1038/s41586-023-05891-2

PMCID:: PMC10929664

Abstract Article PDF–6.3M

Select item 109076062.

Role of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondrial ROS generation and TGF-β1 activity

Jong-Uk Lee, Ki Sung Song, Jisu Hong, Hyesun Shin, Eunji Park, Junyeong Baek, Shinhee Park, Ae-Rin Baek, Junehyuk Lee, An Soo Jang, Do Jin Kim, Su Sie Chin, U-Jin Kim, Sung Hwan Jeong, Sung-Woo Park

Exp Mol Med. 2024 Feb; 56(2): 478–490. Published online 2024 Feb 28. doi: 10.1038/s12276-024-01170-w

PMCID:: PMC10907606

Abstract Article PDF–3.2M

Select item 108867073.

CLPP-Null Eukaryotes with Excess Heme Biosynthesis Show Reduced L-arginine Levels, Probably via CLPX-Mediated OAT Activation

Jana Key, Suzana Gispert, Arvind Reddy Kandi, Daniela Heinz, Andrea Hamann, Heinz D. Osiewacz, David Meierhofer, Georg Auburger

Biomolecules. 2024 Feb; 14(2): 241. Published online 2024 Feb 19. doi: 10.3390/biom14020241

PMCID:: PMC10886707

Abstract Article PDF–2.8M

Select item 103659854.

Image-based quantification of histological features as a function of spatial location using the Tissue Positioning System

Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang, Hao Zhu, Guanghua Xiao, Yunguan Wang

eBioMedicine. 2023 Aug; 94: 104698. Published online 2023 Jul 13. doi: 10.1016/j.ebiom.2023.104698

PMCID:: PMC10365985

Abstract Article PDF–5.4M

Select item 94819335.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 84964206.

Liver homeostasis is maintained by midlobular zone 2 hepatocytes

Yonglong Wei, Yunguan G. Wang, Yuemeng Jia, Lin Li, Jung Yoon, Shuyuan Zhang, Zixi Wang, Yu Zhang, Min Zhu, Tripti Sharma, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Jeffrey H. Albrecht, Phuong T. Le, Clifford J. Rosen, Tao Wang, Hao Zhu

Science. Author manuscript; available in PMC 2021 Oct 7.

Published in final edited form as: Science. 2021 Feb 26; 371(6532): eabb1625. doi: 10.1126/science.abb1625

PMCID:: PMC8496420

Abstract Article PDF–6.4M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 72270288.

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931

PMCID:: PMC7227028

Abstract Article PDF–5.4M

Select item 62980409.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 448439210.

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, Rangjiao Liu, Martin Kircher, Anuradha Lakshminarayana, Belinda S. Harris, Son Yong Karst, Louise A. Dionne, Coleen C. Kane, Michelle Curtain, Melissa L. Berry, Patricia F. Ward-Bailey, Ian Greenstein, Candice Byers, Anne Czechanski, Jocelyn Sharp, Kristina Palmer, Polyxeni Gudis, Whitney Martin, Abby Tadenev, Laurent Bogdanik, C. Herbert Pratt, Bo Chang, David G. Schroeder, Gregory A. Cox, Paul Cliften, Jeffrey Milbrandt, Stephen Murray, Robert Burgess, David E. Bergstrom, Leah Rae Donahue, Hanan Hamamy, Amira Masri, Federico A. Santoni, Periklis Makrythanasis, Stylianos E. Antonarakis, Jay Shendure, Laura G. Reinholdt

Genome Res. 2015 Jul; 25(7): 948–957. doi: 10.1101/gr.186882.114

PMCID:: PMC4484392

Abstract Article PDF–604K

Select item 417174411.

The retarded hair growth (rhg) mutation in mice is an allele of ornithine aminotransferase (Oat)

Jason J. Bisaillon, Legairre A. Radden, II, Eric T. Szabo, Samantha R. Hughes, Aaron M. Feliciano, Alex V. Nesta, Belinda Petrovic, Kenneth M. Palanza, Dainius Lancinskas, Theodore A. Szmurlo, David C. Artus, Martin A. Kapper, James P. Mulrooney, Thomas R. King

Mol Genet Metab Rep. 2014; 1: 378–390. Published online 2014 Sep 16. doi: 10.1016/j.ymgmr.2014.08.002

PMCID:: PMC4171744

Abstract Article PDF–1.3M

Select item 357241012.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 334689613.

Head Bobber: An Insertional Mutation Causes Inner Ear Defects, Hyperactive Circling, and Deafness

Giuseppina Somma, Heather M. Alger, Ryan M. McGuire, Jim D. Kretlow, Fernanda R. Ruiz, Svetlana A. Yatsenko, Pawel Stankiewicz, Wilbur Harrison, Etai Funk, Antonio Bergamaschi, John S. Oghalai, Antonios G. Mikos, Paul A. Overbeek, Fred A. Pereira

J Assoc Res Otolaryngol. 2012 Jun; 13(3): 335–349. Published online 2012 Mar 2. doi: 10.1007/s10162-012-0316-5

PMCID:: PMC3346896

Abstract Article PDF–1.0M

Select item 332215714.

Short-Chain 3-Hydroxyacyl-Coenzyme A Dehydrogenase Associates with a Protein Super-Complex Integrating Multiple Metabolic Pathways

Srinivas B. Narayan, Stephen R. Master, Anthony N. Sireci, Charlene Bierl, Paige E. Stanley, Changhong Li, Charles A. Stanley, Michael J. Bennett

PLoS One. 2012; 7(4): e35048. Published online 2012 Apr 9. doi: 10.1371/journal.pone.0035048

PMCID:: PMC3322157

Abstract Article PDF–219K

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253416.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 277884417.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Abstract Article PDF–1.2M

Select item 272278018.

A Protein Interaction Network for the Large Conductance Ca²⁺-activated K⁺ Channel in the Mouse Cochlea

Thandavarayan Kathiresan, Margaret Harvey, Sandra Orchard, Yoshihisa Sakai, Bernd Sokolowski

Mol Cell Proteomics. 2009 Aug; 8(8): 1972–1987. Published online 2009 May 7. doi: 10.1074/mcp.M800495-MCP200

PMCID:: PMC2722780

Abstract Article PDF–1.0M

Select item 171561119.

Gyrate atrophy of the choroid and retina: assignment of the ornithine aminotransferase structural gene to human chromosome 10 and mouse chromosome 7.

J J O'Donnell, K Vannas-Sulonen, T B Shows, D R Cox

Am J Hum Genet. 1988 Dec; 43(6): 922–928.

PMCID:: PMC1715611

Summary Page Browse PDF–1.1M

Select item 113607020.

Mouse gastric mucin: cloning and chromosomal localization.

L L Shekels, C Lyftogt, M Kieliszewski, J D Filie, C A Kozak, S B Ho

Biochem J. 1995 Nov 1; 311(Pt 3): 775–785. doi: 10.1042/bj3110775

PMCID:: PMC1136070

Summary Page Browse PDF–3.8M

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