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Select item 113675191.

HDAC1 and HDAC2 orchestrate Wnt signaling to regulate neural progenitor transition during brain development

Yue Zhu, Yunyun Huang, Tianxiang Tang, Yunli Xie

iScience. 2024 Sep 20; 27(9): 110600. Published online 2024 Jul 27. doi: 10.1016/j.isci.2024.110600

PMCID:: PMC11367519

Abstract Article PDF–7.4M

Select item 112909702.

Inhibition of endothelial histone deacetylase 2 shifts endothelial-mesenchymal transitions in cerebral arteriovenous malformation models

Yan Zhao, Xiuju Wu, Yang Yang, Li Zhang, Xinjiang Cai, Sydney Chen, Abigail Vera, Jaden Ji, Kristina I. Boström, Yucheng Yao

J Clin Invest. 2024 Aug 1; 134(15): e176758. Published online 2024 May 23. doi: 10.1172/JCI176758

PMCID:: PMC11290970

Abstract Article PDF–2.2M

Select item 111971373.

Microglial histone deacetylase 2 is dispensable for functional and histological outcomes in a mouse model of traumatic brain injury

Yue Zhang, Yongfang Zhao, Yana Wang, Jiaying Li, Yichen Huang, Fan Lyu, Yangfan Wang, Pengju Wei, Yiwen Yuan, Yi Fu, Yanqin Gao

J Cereb Blood Flow Metab. 2024 May; 44(5): 817–835. Published online 2023 Dec 9. doi: 10.1177/0271678X231197173

PMCID:: PMC11197137

Abstract Article PDF–3.7M

Select item 109614284.

Attenuation of neuronal ferroptosis in intracerebral hemorrhage by inhibiting HDAC1/2: Microglial heterogenization via the Nrf2/HO1 pathway

Zhiwen Jiang, Heng Yang, Wei Ni, Xinjie Gao, Xu Pei, Hanqiang Jiang, Jiabin Su, Ruiyuan Weng, Yuchao Fei, Yanqin Gao, Yuxiang Gu

CNS Neurosci Ther. 2024 Mar; 30(3): e14646. Published online 2024 Mar 24. doi: 10.1111/cns.14646

PMCID:: PMC10961428

Abstract Article PDF–25M

Select item 108538945.

Gut microbiota regulates hepatic ischemia–reperfusion injury‐induced cognitive dysfunction via the HDAC2‐ACSS2 axis in mice

Yanbo Liu, Zhen Li, Tianning Sun, Zhixiao Li, Anne Manyande, Hongbing Xiang, Zhigang He

CNS Neurosci Ther. 2024 Feb; 30(2): e14610. Published online 2024 Feb 9. doi: 10.1111/cns.14610

PMCID:: PMC10853894

Abstract Article PDF–6.2M

Select item 108425226.

Hdac1 and Hdac2 positively regulate Notch1 gain-of-function pathogenic signaling in committed osteoblasts of male mice

Haydee M. Torres, Leetoria Hinojosa, Ashley M. VanCleave, Tania Rodezno, Jennifer J. Westendorf, Jianning Tao

Birth Defects Res. Author manuscript; available in PMC 2025 Jan 1.

Published in final edited form as: Birth Defects Res. 2024 Jan; 116(1): e2266. Published online 2023 Nov 3. doi: 10.1002/bdr2.2266

PMCID:: PMC10842522

Abstract Article PDF–482K

Select item 108046257.

HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling

Michela Terri, Pilar Sandoval, Giulio Bontempi, Claudia Montaldo, Henar Tomero-Sanz, Valeria de Turris, Flavia Trionfetti, Lucía Pascual-Antón, Irene Clares-Pedrero, Cecilia Battistelli, Sergio Valente, Clemens Zwergel, Antonello Mai, Laura Rosanò, Miguel Ángel del Pozo, Miguel Sánchez-Álvarez, Carlos Cabañas, Marco Tripodi, Manuel López-Cabrera, Raffaele Strippoli

J Exp Clin Cancer Res. 2024; 43: 27. Published online 2024 Jan 23. doi: 10.1186/s13046-023-02930-8

PMCID:: PMC10804625

Abstract Article PDF–7.7M

Select item 106157658.

Acan downregulation in parvalbumin GABAergic cells reduces spontaneous recovery of fear memories

Marisol Lavertu-Jolin, Bidisha Chattopadhyaya, Pegah Chehrazi, Denise Carrier, Florian Wünnemann, Séverine Leclerc, Félix Dumouchel, Derek Robertson, Hicham Affia, Kamal Saba, Vijaya Gopal, Anant Bahadur Patel, Gregor Andelfinger, Graçiela Pineyro, Graziella Di Cristo

Mol Psychiatry. 2023; 28(7): 2946–2963. Published online 2023 May 2. doi: 10.1038/s41380-023-02085-0

PMCID:: PMC10615765

Abstract Article PDF–6.6M

Select item 104154069.

Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche

Hadas Sibony-Benyamini, Emil Aamar, David Enshell-Seijffers

Nat Commun. 2023; 14: 4820. Published online 2023 Aug 10. doi: 10.1038/s41467-023-40573-7

PMCID:: PMC10415406

Abstract Article PDF–26M

Select item 1011667610.

Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation

Jiamin Jin, Peipei Ren, Xiang Li, Yinyi Zhang, Weijie Yang, Yerong Ma, Mengru Lai, Chao Yu, Songying Zhang, Yin-Li Zhang

Epigenetics Chromatin. 2023; 16: 11. Published online 2023 Apr 19. doi: 10.1186/s13072-023-00485-8

PMCID:: PMC10116676

Abstract Article PDF–14M

Select item 1010331111.

Cell Cycle and Senescence Regulation by Podocyte Histone Deacetylase 1 and 2

Paulina X. Medina Rangel, Elizabeth Cross, Chang Liu, Christopher E. Pedigo, Xuefei Tian, Elena Gutiérrez-Calabrés, Soichiro Nagata, Anupama Priyadarshini, Gabriel Lerner, Patricia Bunda, Sudhir Perincheri, Jianlei Gu, Hongyu Zhao, Ying Wang, Kazunori Inoue, Shuta Ishibe

J Am Soc Nephrol. 2023 Mar; 34(3): 433–450. Published online 2022 Nov 22. doi: 10.1681/ASN.2022050598

PMCID:: PMC10103311

Abstract Article

Select item 973283212.

HDAC2 in Primary Sensory Neurons Constitutively Restrains Chronic Pain by Repressing α2δ-1 Expression and Associated NMDA Receptor Activity

Jixiang Zhang, Shao-Rui Chen, Meng-Hua Zhou, Daozhong Jin, Hong Chen, Li Wang, Ronald A. DePinho, Hui-Lin Pan

J Neurosci. 2022 Nov 30; 42(48): 8918–8935. doi: 10.1523/JNEUROSCI.0735-22.2022

PMCID:: PMC9732832

Abstract Article PDF–6.3M

Select item 960672213.

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development

Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener

Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.

Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002

PMCID:: PMC9606722

Abstract Article PDF–6.7M

Select item 960442814.

Mother–Fetus Immune Cross-Talk Coordinates “Extrinsic”/“Intrinsic” Embryo Gene Expression Noise and Growth Stability

Tatyana Ivanovna Babochkina, Ludmila Alekseevna Gerlinskaya, Margarita Vladimirovna Anisimova, Galina Vladimirovna Kontsevaya, Natalia Aleksandrovna Feofanova, Aliya Konstantinovna Stanova, Mikhail Pavlovich Moshkin, Yuri Mikhailovich Moshkin

Int J Mol Sci. 2022 Oct; 23(20): 12467. Published online 2022 Oct 18. doi: 10.3390/ijms232012467

PMCID:: PMC9604428

Abstract Article PDF–2.3M

Select item 940915915.

Smoking Cessation in Mice Does Not Switch off Persistent Lung Inflammation and Does Not Restore the Expression of HDAC2 and SIRT1

Giovanna De Cunto, Simone De Meo, Barbara Bartalesi, Eleonora Cavarra, Giuseppe Lungarella, Monica Lucattelli

Int J Mol Sci. 2022 Aug; 23(16): 9104. Published online 2022 Aug 14. doi: 10.3390/ijms23169104

PMCID:: PMC9409159

Abstract Article PDF–6.2M

Select item 935971816.

HDAC2 Facilitates Pancreatic Cancer Metastasis

Lukas Krauß, Bettina C. Urban, Sieglinde Hastreiter, Carolin Schneider, Patrick Wenzel, Zonera Hassan, Matthias Wirth, Katharina Lankes, Andrea Terrasi, Christine Klement, Filippo M. Cernilogar, Rupert Öllinger, Niklas de Andrade Krätzig, Thomas Engleitner, Roland M. Schmid, Katja Steiger, Roland Rad, Oliver H. Krämer, Maximilian Reichert, Gunnar Schotta, Dieter Saur, Günter Schneider

Cancer Res. 2022 Feb 15; 82(4): 695–707. Published online 2021 Dec 13. doi: 10.1158/0008-5472.CAN-20-3209