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Items: 1 to 20 of 30

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
NANOG initiates epiblast fate through the coordination of pluripotency genes expression
Nicolas Allègre, Sabine Chauveau, Cynthia Dennis, Yoan Renaud, Dimitri Meistermann, Lorena Valverde Estrella, Pierre Pouchin, Michel Cohen-Tannoudji, Laurent David, Claire Chazaud
Nat Commun. 2022; 13: 3550. Published online 2022 Jun 21. doi: 10.1038/s41467-022-30858-8
PMCID:
PMC9213552
AbstractArticlePDF–4.4M
3.
DAJIN enables multiplex genotyping to simultaneously validate intended and unintended target genome editing outcomes
Akihiro Kuno, Yoshihisa Ikeda, Shinya Ayabe, Kanako Kato, Kotaro Sakamoto, Sayaka R. Suzuki, Kento Morimoto, Arata Wakimoto, Natsuki Mikami, Miyuki Ishida, Natsumi Iki, Yuko Hamada, Megumi Takemura, Yoko Daitoku, Yoko Tanimoto, Tra Thi Huong Dinh, Kazuya Murata, Michito Hamada, Masafumi Muratani, Atsushi Yoshiki, Fumihiro Sugiyama, Satoru Takahashi, Seiya Mizuno
PLoS Biol. 2022 Jan; 20(1): e3001507. Published online 2022 Jan 18. doi: 10.1371/journal.pbio.3001507
PMCID:
PMC8765641
AbstractArticlePDF–5.7M
4.
Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats
Toshihiro Kobayashi, Teppei Goto, Mami Oikawa, Makoto Sanbo, Fumika Yoshida, Reiko Terada, Naoko Niizeki, Naoyo Kajitani, Kanako Kazuki, Yasuhiro Kazuki, Shinichi Hochi, Hiromitsu Nakauchi, M. Azim Surani, Masumi Hirabayashi
Nat Commun. 2021; 12: 1328. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21557-x
PMCID:
PMC7910474
AbstractArticlePDF–7.9M
5.
The pluripotency regulator PRDM14 requires hematopoietic regulator CBFA2T3 to initiate leukemia in mice
Lauren J. Tracey, Travis Brooke-Bisschop, Pascal W.T.C. Jansen, Eric I. Campos, Michiel Vermeulen, Monica J. Justice
Mol Cancer Res. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Mol Cancer Res. 2019 Jul; 17(7): 1468–1479. Published online 2019 Apr 23. doi: 10.1158/1541-7786.MCR-18-1327
PMCID:
PMC6610658
AbstractArticlePDF–2.1M
6.
PRDM14 controls X-chromosomal and global epigenetic reprogramming of H3K27me3 in migrating mouse primordial germ cells
Anna Mallol, Maria Guirola, Bernhard Payer
Epigenetics Chromatin. 2019; 12: 38. Published online 2019 Jun 20. doi: 10.1186/s13072-019-0284-7
PMCID:
PMC6585054
AbstractArticlePDF–1.4M
7.
Esrrb Complementation Rescues Development of Nanog-Null Germ Cells
Man Zhang, Harry G. Leitch, Walfred W.C. Tang, Nicola Festuccia, Elisa Hall-Ponsele, Jennifer Nichols, M. Azim Surani, Austin Smith, Ian Chambers
Cell Rep. 2018 Jan 9; 22(2): 332–339. Published online 2018 Jan 9. doi: 10.1016/j.celrep.2017.12.060
PMCID:
PMC5775501
AbstractArticle
8.
Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer
Hiroaki Taniguchi, Daisuke Hoshino, Chiharu Moriya, Hitoshi Zembutsu, Nobuhiro Nishiyama, Hiroyuki Yamamoto, Kazunori Kataoka, Kohzoh Imai
Oncotarget. 2017 Jul 18; 8(29): 46856–46874. Published online 2017 Apr 1. doi: 10.18632/oncotarget.16776
PMCID:
PMC5564528
AbstractArticlePDF–16M
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency
Naoki Okashita, Yoshiaki Suwa, Osamu Nishimura, Nao Sakashita, Mitsutaka Kadota, Go Nagamatsu, Masanori Kawaguchi, Hiroki Kashida, Ayaka Nakajima, Makoto Tachibana, Yoshiyuki Seki
Stem Cell Reports. 2016 Dec 13; 7(6): 1072–1086. Published online 2016 Nov 17. doi: 10.1016/j.stemcr.2016.10.007
PMCID:
PMC5161533
AbstractArticlePDF–2.6M
11.
CO-REPRESSOR CBFA2T2 REGULATES PLURIPOTENCY AND GERMLINE DEVELOPMENT
Shengjiang Tu, Varun Narendra, Masashi Yamaji, Simon E Vidal, Luis Alejandro Rojas, Xiaoshi Wang, Sang Yong Kim, Benjamin A Garcia, Thomas Tuschl, Matthias Stadtfeld, Danny Reinberg
Nature. Author manuscript; available in PMC 2016 Dec 8.
Published in final edited form as: Nature. 2016 Jun 16; 534(7607): 387–390. Published online 2016 Jun 8. doi: 10.1038/nature18004
PMCID:
PMC4911307
AbstractArticlePDF–2.1M
12.
ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation
Nataliya Nady, Ankit Gupta, Ziyang Ma, Tomek Swigut, Akiko Koide, Shohei Koide, Joanna Wysocka
eLife. 2015; 4: e10150. Published online 2015 Nov 2. doi: 10.7554/eLife.10150
PMCID:
PMC4749557
AbstractArticlePDF–3.9M
13.
Histone Demethylation Maintains Prdm14 and Tsix Expression and Represses Xist in Embryonic Stem Cells
Yasunao F. Kamikawa, Mary E. Donohoe
PLoS One. 2015; 10(5): e0125626. Published online 2015 May 20. doi: 10.1371/journal.pone.0125626
PMCID:
PMC4439117
AbstractArticlePDF–2.9M
14.
Tsix RNA and the germline factor, PRDM14, link X-reactivation and stem cell reprogramming
Bernhard Payer, Michael Rosenberg, Masashi Yamaji, Yukihiro Yabuta, Michiyo Koyanagi-Aoi, Katsuhiko Hayashi, Shinya Yamanaka, Mitinori Saitou, Jeannie T. Lee
Mol Cell. Author manuscript; available in PMC 2014 Jun 26.
Published in final edited form as: Mol Cell. 2013 Dec 26; 52(6): 805–818. Published online 2013 Nov 21. doi: 10.1016/j.molcel.2013.10.023
PMCID:
PMC3950835
AbstractArticlePDF–3.1M
15.
Ground-State Conditions Promote Robust Prdm14 Reactivation and Maintain an Active Dlk1-Dio3 Region during Reprogramming
Omer Habib, Gizem Habib, Sung-Hwan Moon, Ki-Sung Hong, Jeong Tae Do, Youngsok Choi, Sung Woon Chang, Hyung-Min Chung
Mol Cells. 2014 Jan 31; 37(1): 31–35. Published online 2014 Jan 27. doi: 10.14348/molcells.2014.2212
PMCID:
PMC3907008
AbstractArticlePDF–11M
16.
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL)
Brandi L. Carofino, Bernard Ayanga, Monica J. Justice
Dis Model Mech. 2013 Nov; 6(6): 1494–1506. Published online 2013 Sep 5. doi: 10.1242/dmm.012575
PMCID:
PMC3820272
AbstractArticle
17.
A tripartite transcription factor network regulates primordial germ cell specification in mice
Erna Magnúsdóttir, Sabine Dietmann, Kazuhiro Murakami, Ufuk Günesdogan, Fuchou Tang, Siqin Bao, Evangelia Diamanti, Kaiqin Lao, Bertie Gottgens, M. Azim Surani
Nat Cell Biol. Author manuscript; available in PMC 2014 Feb 1.
Published in final edited form as: Nat Cell Biol. 2013 Aug; 15(8): 905–915. Published online 2013 Jul 14. doi: 10.1038/ncb2798
PMCID:
PMC3796875
AbstractArticlePDF–4.0M
18.
Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation
Nils Grabole, Julia Tischler, Jamie A Hackett, Shinseog Kim, Fuchou Tang, Harry G Leitch, Erna Magnúsdóttir, M Azim Surani
EMBO Rep. 2013 Jul; 14(7): 629–637. Published online 2013 May 14. doi: 10.1038/embor.2013.67
PMCID:
PMC3701237
AbstractArticlePDF–1.4M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Epiblast Stem Cell-Based System Reveals Reprogramming Synergy of Germline Factors
Astrid Gillich, Siqin Bao, Nils Grabole, Katsuhiko Hayashi, Matthew W.B. Trotter, Vincent Pasque, Erna Magnúsdóttir, M. Azim Surani
Cell Stem Cell. 2012 Apr 6; 10(4): 425–439. doi: 10.1016/j.stem.2012.01.020
PMCID:
PMC3343665
AbstractArticlePDF–3.4M

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