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Select item 111658891.

Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS

Sonia Vazquez-Sanchez, Britt Tilkin, Fatima Gasset-Rosa, Sitao Zhang, Diana Piol, Melissa McAlonis-Downes, Jonathan Artates, Noe Govea-Perez, Yana Verresen, Lin Guo, Don W. Cleveland, James Shorter, Sandrine Da Cruz

Mol Neurodegener. 2024; 19: 46. Published online 2024 Jun 11. doi: 10.1186/s13024-024-00737-5

PMCID:: PMC11165889

Abstract Article PDF–2.8M

Select item 111627722.

FUS reads histone H3K36me3 to regulate alternative polyadenylation

Junqi Jia, Haonan Fan, Xinyi Wan, Yuan Fang, Zhuoning Li, Yin Tang, Yanjun Zhang, Jun Huang, Dong Fang

Nucleic Acids Res. 2024 Jun 10; 52(10): 5549–5571. Published online 2024 Mar 18. doi: 10.1093/nar/gkae184

PMCID:: PMC11162772

Abstract Article PDF–2.7M

Select item 111582283.

Analysis of CHOP rearrangement in pleomorphic liposarcomas using fluorescence in situ hybridization

Shintaro Sugita, Kunihiko Seki, Karin Yokozawa, Naobumi Tochigi, Koh Furuta, Masanori Hisaoka, Hiroshi Hashimoto, Tadakazu Shimoda, Tadashi Hasegawa

Cancer Sci. 2009 Jan; 100(1): 82–87. Published online 2008 Nov 25. doi: 10.1111/j.1349-7006.2008.01008.x

PMCID:: PMC11158228

Abstract Article PDF–443K

Select item 110469184.

Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development

Parmida Ranji, Emma Jonasson, Lisa Andersson, Stefan Filges, Manuel Luna Santamaría, Christoffer Vannas, Soheila Dolatabadi, Anna Gustafsson, Ola Myklebost, Joakim Håkansson, Henrik Fagman, Göran Landberg, Pierre Åman, Anders Ståhlberg

J Transl Med. 2024; 22: 389. Published online 2024 Apr 26. doi: 10.1186/s12967-024-05211-w

PMCID:: PMC11046918

Abstract Article PDF–2.1M

Select item 110241095.

An aberrant fused in sarcoma liquid droplet of amyotrophic lateral sclerosis pathological variant, R495X, accelerates liquid–solid phase transition

Yutaro Shiramasa, Ryu Yamamoto, Norika Kashiwagi, Fuka Sasaki, Sawaka Imai, Mikihito Ike, Soichiro Kitazawa, Tomoshi Kameda, Ryo Kitahara

Sci Rep. 2024; 14: 8914. Published online 2024 Apr 17. doi: 10.1038/s41598-024-59604-4

PMCID:: PMC11024109

Abstract Article PDF–6.9M

Select item 109711676.

Cell-Type-Dependent Recruitment Dynamics of FUS Protein at Laser-Induced DNA Damage Sites

Yu Niu, Arun Pal, Barbara Szewczyk, Julia Japtok, Marcel Naumann, Hannes Glaß, Andreas Hermann

Int J Mol Sci. 2024 Mar; 25(6): 3526. Published online 2024 Mar 20. doi: 10.3390/ijms25063526

PMCID:: PMC10971167

Abstract Article PDF–5.6M

Select item 109366397.

LncRNA ABHD11-AS1 activates EGFR signaling to promote cervical cancer progression by preventing FUS-mediated degradation of ABHD11 mRNA

Ting Yang, Sijuan Tian, Juan Zhao, Meili Pei, Minyi Zhao, Xiaofeng Yang

Cell Cycle. 2023; 22(23-24): 2538–2551. Published online 2023 Dec 26. doi: 10.1080/15384101.2023.2297591

PMCID:: PMC10936639

Abstract Article PDF–5.6M

Select item 109250638.

FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease

Manohar Kodavati, Haibo Wang, Wenting Guo, Joy Mitra, Pavana M. Hegde, Vincent Provasek, Vikas H. Maloji Rao, Indira Vedula, Aijun Zhang, Sankar Mitra, Alan E. Tomkinson, Dale J. Hamilton, Ludo Van Den Bosch, Muralidhar L. Hegde

Nat Commun. 2024; 15: 2156. Published online 2024 Mar 9. doi: 10.1038/s41467-024-45978-6

PMCID:: PMC10925063

Abstract Article PDF–3.1M

Select item 109123639.

RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation

Clément Demongin, Samuel Tranier, Vandana Joshi, Léa Ceschi, Bénédicte Desforges, David Pastré, Loic Hamon

J Biol Chem. 2024 Mar; 300(3): 105716. Published online 2024 Feb 2. doi: 10.1016/j.jbc.2024.105716

PMCID:: PMC10912363

Abstract Article PDF–5.8M

Select item 1076495810.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 1076448511.

Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs

Yingli Zhu, Thibaut Burg, Katrien Neyrinck, Tim Vervliet, Fatemeharefeh Nami, Ellen Vervoort, Karan Ahuja, Maria Livia Sassano, Yoke Chin Chai, Arun Kumar Tharkeshwar, Jonathan De Smedt, Haibo Hu, Geert Bultynck, Patrizia Agostinis, Johannes V. Swinnen, Ludo Van Den Bosch, Rodrigo Furtado Madeiro da Costa, Catherine Verfaillie

Acta Neuropathol. 2024; 147(1): 6. Published online 2024 Jan 3. doi: 10.1007/s00401-023-02666-x

Correction in:: Acta Neuropathol. 2024; 147(1): 99.

PMCID:: PMC10764485

Abstract Article PDF–13M

Select item 1076197112.

Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions

Julia Schöpf, Sebastian Uhrig, Christoph E. Heilig, Kwang-Seok Lee, Tatjana Walther, Alexander Carazzato, Anna Maria Dobberkau, Dieter Weichenhan, Christoph Plass, Mark Hartmann, Gaurav D. Diwan, Zunamys I. Carrero, Claudia R. Ball, Tobias Hohl, Thomas Kindler, Patricia Rudolph-Hähnel, Dominic Helm, Martin Schneider, Anna Nilsson, Ingrid Øra, Roland Imle, Ana Banito, Robert B. Russell, Barbara C. Jones, Daniel B. Lipka, Hanno Glimm, Daniel Hübschmann, Wolfgang Hartmann, Stefan Fröhling, Claudia Scholl

Nat Commun. 2024; 15: 51. Published online 2024 Jan 2. doi: 10.1038/s41467-023-44360-2

PMCID:: PMC10761971

Abstract Article PDF–3.4M

Select item 1068705613.

“Boundary residues” between the folded RNA recognition motif and disordered RGG domains are critical for FUS–RNA binding

Sangeetha Balasubramanian, Shovamayee Maharana, Anand Srivastava

J Biol Chem. 2023 Dec; 299(12): 105392. Published online 2023 Oct 27. doi: 10.1016/j.jbc.2023.105392

PMCID:: PMC10687056

Abstract Article PDF–4.6M

Select item 1067639014.

LINC01133 can induce acquired ferroptosis resistance by enhancing the FSP1 mRNA stability through forming the LINC01133-FUS-FSP1 complex

Shaowen Wang, Jionghuang Chen, Pengping Li, Yangchao Chen

Cell Death Dis. 2023 Nov; 14(11): 767. Published online 2023 Nov 25. doi: 10.1038/s41419-023-06311-z

PMCID:: PMC10676390

Abstract Article PDF–2.6M

Select item 1066672515.

FUS regulates the alternative splicing of cell proliferation genes related to atherosclerosis

Jianjun Hou, Shaobing Yang, Ying Guo, Ning Yan, Shaobin Jia

Exp Biol Med (Maywood) 2023 Sep; 248(17): 1459–1468. Published online 2023 Sep 9. doi: 10.1177/15353702231187642

PMCID:: PMC10666725

Abstract Article PDF–3.0M

Select item 1065258216.

Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition

Mari Carmen Pelaez, Antoine Desmeules, Pauline A. Gelon, Bastien Glasson, Laetitia Marcadet, Alicia Rodgers, Daniel Phaneuf, Silvia Pozzi, Paul A. Dutchak, Jean-Pierre Julien, Chantelle F. Sephton

Acta Neuropathol Commun. 2023; 11: 182. Published online 2023 Nov 16. doi: 10.1186/s40478-023-01671-1

PMCID:: PMC10652582

Abstract Article PDF–4.6M

Select item 1061767317.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 1060494318.

lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons

Vincent E. Provasek, Manohar Kodavati, Wenting Guo, Haibo Wang, Istvan Boldogh, Ludo Van Den Bosch, Gavin Britz, Muralidhar L. Hegde

Cells. 2023 Oct; 12(20): 2461. Published online 2023 Oct 16. doi: 10.3390/cells12202461

PMCID:: PMC10604943

Abstract Article PDF–4.5M

Select item 1056587619.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1055677720.

Binding of the nuclear ribonucleoprotein family member FUS to RNA prevents R-loop RNA:DNA hybrid structures

Valery F. Thompson, Daniel R. Wieland, Vivian Mendoza-Leon, Helen I. Janis, Michelle A. Lay, Lucas M. Harrell, Jacob C. Schwartz

J Biol Chem. 2023 Oct; 299(10): 105237. Published online 2023 Sep 9. doi: 10.1016/j.jbc.2023.105237

PMCID:: PMC10556777

Abstract Article PDF–1.3M

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