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Items: 1 to 20 of 699

1.
Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation
Rinako Nakagawa, Miriam Llorian, Sunita Varsani-Brown, Probir Chakravarty, Jeannie M. Camarillo, David Barry, Roger George, Neil P. Blackledge, Graham Duddy, Neil L. Kelleher, Robert J. Klose, Martin Turner, Dinis P. Calado
Nat Commun. 2024; 15: 10516. Published online 2024 Dec 3. doi: 10.1038/s41467-024-54937-0
PMCID:
PMC11615350
AbstractArticlePDF–4.3M
2.
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O. Watzlawik, Yin Maggie Chen, Ariel L. Raybuck, Daniel D. Billadeau, Virginia Smith Shapiro, Wolfdieter Springer, Jie Sun, Mark R. Boothby, Hu Zeng
Nat Commun. 2024; 15: 10163. Published online 2024 Nov 23. doi: 10.1038/s41467-024-54344-5
PMCID:
PMC11585635
AbstractArticlePDF–5.8M
3.
Metabolic fitness of IgA+ plasma cells in the gut requires DOCK8
Biyan Zhang, Shuting Chen, Xiangyun Yin, Caleb D. McBride, Jake A. Gertie, Marina Yurieva, Agata A. Bielecka, Brian Hoffmann, J. Travis Hinson, Jessica Grassmann, Lan Xu, Emily R. Siniscalco, Arielle Soldatenko, Laura Hoyt, Julie Joseph, Elizabeth B. Norton, Gowthaman Uthaman, Noah W. Palm, Elise Liu, Stephanie C. Eisenbarth, Adam Williams
Mucosal Immunol. Author manuscript; available in PMC 2024 Nov 18.
Published in final edited form as: Mucosal Immunol. 2024 Jun; 17(3): 431–449. Published online 2023 Dec 28. doi: 10.1016/j.mucimm.2023.12.001
PMCID:
PMC11571232
AbstractArticlePDF–2.3M
4.
Humoral and T-cell-mediated responses to an insect-specific flavivirus-based Zika virus vaccine candidate
Danielle L. Porier, Awadalkareem Adam, Lin Kang, Pawel Michalak, Juselyn Tupik, Matthew A. Santos, Manette Tanelus, Krisangel López, Dawn I. Auguste, Christy Lee, Irving C. Allen, Tian Wang, Albert J. Auguste
PLoS Pathog. 2024 Oct; 20(10): e1012566. Published online 2024 Oct 10. doi: 10.1371/journal.ppat.1012566
PMCID:
PMC11495591
AbstractArticlePDF–2.3M
5.
A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation and shortened lifespan
Ana Ortega-Molina, Cristina Lebrero-Fernández, Alba Sanz, Miguel Calvo-Rubio, Nerea Deleyto-Seldas, Lucía de Prado-Rivas, Ana Belén Plata-Gómez, Elena Fernández-Florido, Patricia González-García, Yurena Vivas-García, Elena Sánchez García, Osvaldo Graña-Castro, Nathan L. Price, Alejandra Aroca-Crevillén, Eduardo Caleiras, Daniel Monleón, Consuelo Borrás, María Casanova-Acebes, Rafael de Cabo, Alejo Efeyan
Nat Aging. 2024; 4(8): 1102–1120. Published online 2024 Jun 7. doi: 10.1038/s43587-024-00635-x
PMCID:
PMC11333293
AbstractArticlePDF–10M
6.
Immunological correlates of protection mediated by a whole organism, Cryptococcus neoformans, vaccine deficient in chitosan
Charles A. Specht, Ruiying Wang, Lorena V. N. Oliveira, Maureen M. Hester, Christina Gomez, Zhongming Mou, Diana Carlson, Chrono K. Lee, Camaron R. Hole, Woei C. Lam, Rajendra Upadhya, Jennifer K. Lodge, Stuart M. Levitz
mBio. 2024 Aug; 15(8): e01746-24. Published online 2024 Jul 9. doi: 10.1128/mbio.01746-24
PMCID:
PMC11323574
AbstractArticlePDF–1.8M
7.
Age-associated accumulation of B cells promotes macrophage inflammation and inhibits lipolysis in adipose tissue during sepsis
Anna Carey, Katie Nguyen, Pranathi Kandikonda, Victor Kruglov, Claire Bradley, Korbyn J.V. Dahlquist, Stephanie Cholensky, Whitney Swanson, Vladimir P. Badovinac, Thomas S. Griffith, Christina D. Camell
Cell Rep. Author manuscript; available in PMC 2024 Apr 12.
Published in final edited form as: Cell Rep. 2024 Mar 26; 43(3): 113967. Published online 2024 Mar 15. doi: 10.1016/j.celrep.2024.113967
PMCID:
PMC11014686
AbstractArticlePDF–2.7M
8.
Ion channel TRPV2 is critical in enhancing B cell activation and function
Cuifeng Li, Meng Zhao, Xiaohang Liu, Yuxin Li, Bihua Xu, Lina Zhou, Xiaolin Sun, Wenbo Sun, Na Kang, Zhenglin Ji, Tong Li, Haoran An, Fei Wang, Chuan Wu, Jing-Ying Ye, Jing-Ren Zhang, Qingwen Wang, Xiaodong Zhao, Zhanguo Li, Wanli Liu
J Exp Med. 2024 Mar 4; 221(3): e20221042. Published online 2024 Feb 14. doi: 10.1084/jem.20221042
PMCID:
PMC10866685
AbstractArticlePDF–5.5M
9.
Promotion of Colitis in B Cell-Deficient C57BL/6 Mice Infected with Enterotoxigenic Bacteroides fragilis
Minjeong Jo, Soonjae Hwang, Chang-Gun Lee, Ju-Eun Hong, Da-Hye Kang, Sang-Hyeon Yoo, Woo-Seung Kim, Jung-Yoon Yoo, Ki-Jong Rhee
Int J Mol Sci. 2024 Jan; 25(1): 364. Published online 2023 Dec 27. doi: 10.3390/ijms25010364
PMCID:
PMC10778593
AbstractArticlePDF–2.6M
10.
Secreted IgM modulates IL-10 expression in B cells
Shannon Eileen McGettigan, Lazaro Emilio Aira, Gaurav Kumar, Romain Ballet, Eugene C. Butcher, Nicole Baumgarth, Gudrun F. Debes
Nat Commun. 2024; 15: 324. Published online 2024 Jan 5. doi: 10.1038/s41467-023-44382-w
PMCID:
PMC10773282
AbstractArticlePDF–1.5M
11.
Intranasal immunization with an RBD-hemagglutinin fusion protein harnesses preexisting immunity to enhance antigen-specific responses
Atsushi Kawai, Nagisa Tokunoh, Eigo Kawahara, Shigeyuki Tamiya, Shinya Okamura, Chikako Ono, Jessica Anindita, Hiroki Tanaka, Hidetaka Akita, Sho Yamasaki, Jun Kunisawa, Toru Okamoto, Yoshiharu Matsuura, Toshiro Hirai, Yasuo Yoshioka
J Clin Invest. 2023 Dec 1; 133(23): e166827. Published online 2023 Dec 1. doi: 10.1172/JCI166827
PMCID:
PMC10688985
AbstractArticlePDF–3.8M
12.
Bruton's Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae
Zhe Liu, Alexander P.N.A. De Porto, Regina De Beer, Joris J.T.H. Roelofs, Onno J. De Boer, Sandrine Florquin, Cornelis Van't Veer, Rudi W. Hendriks, Tom Van der Poll, Alex F. De Vos
J Innate Immun. 2023 Jan-Dec; 15(1): 1–15. Published online 2022 May 10. doi: 10.1159/000524583
PMCID:
PMC10643901
AbstractArticlePDF–1.0M
13.
Fasting-Mimicking Diet Drives Antitumor Immunity against Colorectal Cancer by Reducing IgA-Producing Cells
Ziwen Zhong, Hao Zhang, Ke Nan, Jing Zhong, Qichao Wu, Lihong Lu, Ying Yue, Zhenyu Zhang, Miaomiao Guo, Zhiqiang Wang, Jie Xia, Yun Xing, Ying Fu, Baichao Yu, Wenchang Zhou, Xingfeng Sun, Yang Shen, Wankun Chen, Jie Zhang, Jin Zhang, Duan Ma, Yiwei Chu, Ronghua Liu, Changhong Miao
Cancer Res. 2023 Nov 1; 83(21): 3529–3543. Published online 2023 Aug 21. doi: 10.1158/0008-5472.CAN-23-0323
PMCID:
PMC10618736
AbstractArticlePDF–13M
14.
Female But Not Male Mice Deficient in Soluble IgM are Susceptible to Chemically-Induced Glomerular Injury
Russell Whelan, Andrew Feemster, Jennifer Laskowski, Brandon Renner, Liudmila Kulik, Felix Poppelaars, Cameron Lee, V. Michael Holers, Joshua M. Thurman
J Immunol. Author manuscript; available in PMC 2024 Oct 15.
Published in final edited form as: J Immunol. 2023 Oct 15; 211(8): 1240–1248. doi: 10.4049/jimmunol.2200292
PMCID:
PMC10592129
AbstractArticlePDF–2.6M
15.
Antigen receptor signaling and cell death resistance controls intestinal humoral response zonation
Fiona Raso, Shuozhi Liu, Mikala JoAnn Willett, Gregory Barton, Christian Thomas Mayer, Oliver Bannard, Mridu Acharya, Jagan R. Muppidi, Ann Marshak-Rothstein, Andrea Reboldi
Immunity. Author manuscript; available in PMC 2024 Oct 10.
Published in final edited form as: Immunity. 2023 Oct 10; 56(10): 2373–2387.e8. Published online 2023 Sep 14. doi: 10.1016/j.immuni.2023.08.018
PMCID:
PMC10591993
AbstractArticlePDF–1.5M
16.
mAb therapy controls CNS‐resident lyssavirus infection via a CD4 T cell‐dependent mechanism
Kate E Mastraccio, Celeste Huaman, Si'Ana A Coggins, Caitlyn Clouse, Madeline Rader, Lianying Yan, Pratyusha Mandal, Imran Hussain, Anwar E Ahmed, Trung Ho, Austin Feasley, Bang K Vu, Ina L Smith, Wanda Markotter, Dawn L Weir, Eric D Laing, Christopher C Broder, Brian C Schaefer
EMBO Mol Med. 2023 Oct; 15(10): e16394. Published online 2023 Sep 28. doi: 10.15252/emmm.202216394
PMCID:
PMC10565638
AbstractArticlePDF–4.1M
17.
Interactions between B cells and T follicular regulatory cells enhance susceptibility to Brucella infection independent of the anti-Brucella humoral response
Alexis S. Dadelahi, Mostafa F. N. Abushahba, Bárbara Ponzilacqua-Silva, Catherine A. Chambers, Charles R. Moley, Carolyn A. Lacey, Alexander L. Dent, Jerod A. Skyberg
PLoS Pathog. 2023 Sep; 19(9): e1011672. Published online 2023 Sep 18. doi: 10.1371/journal.ppat.1011672
PMCID:
PMC10538787
AbstractArticlePDF–2.7M
18.
Gut bacteria induce IgA expression in pituitary hormone-secreting cells during aging
Yehua Li, Jiawen Wang, Rui Wang, Ying Chang, Xiaodong Wang
iScience. 2023 Oct 20; 26(10): 107747. Published online 2023 Aug 26. doi: 10.1016/j.isci.2023.107747
PMCID:
PMC10492204
AbstractArticlePDF–3.9M
19.
B cell extracellular vesicles contain monomeric IgM that binds antigen and enters target cells
Michael F. Gutknecht, Nichol E. Holodick, Thomas L. Rothstein
iScience. 2023 Sep 15; 26(9): 107526. Published online 2023 Aug 3. doi: 10.1016/j.isci.2023.107526
PMCID:
PMC10448175
AbstractArticlePDF–6.3M
20.
Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
Zoe Goldberger, Sylvie Hauert, Kevin Chang, Trevin Kurtanich, Aaron T. Alpar, Grégoire Repond, Yue Wang, Suzana Gomes, Raga Krishnakumar, Prabha Siddarth, Melody A. Swartz, Jeffrey A. Hubbell, Priscilla S. Briquez
Cell Rep Med. 2023 Aug 15; 4(8): 101145. Published online 2023 Aug 7. doi: 10.1016/j.xcrm.2023.101145
PMCID:
PMC10439248
AbstractArticlePDF–5.8M

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