PMC Links for GEO Profiles (Select 75886003) - PMC - NCBI

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Items: 13

Select item 108547921.

Synergistic Protection of Retinal Ganglion Cells (RGCs) by SARM1 Inactivation with CNTF in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy

Yan Guo, Zara Mehrabian, Jeffrey Milbrandt, Aaron DiAntonio, Steven L. Bernstein

Cells. 2024 Feb; 13(3): 202. Published online 2024 Jan 23. doi: 10.3390/cells13030202

PMCID:: PMC10854792

Abstract Article PDF–11M

Select item 97118782.

A SARM1-mitochondrial feedback loop drives neuropathogenesis in a Charcot-Marie-Tooth disease type 2A rat model

Yurie Sato-Yamada, Amy Strickland, Yo Sasaki, Joseph Bloom, Aaron DiAntonio, Jeffrey Milbrandt

J Clin Invest. 2022 Dec 1; 132(23): e161566. Published online 2022 Dec 1. doi: 10.1172/JCI161566

PMCID:: PMC9711878

Abstract Article PDF–7.0M

Select item 77363043.

Cisplatin induced neurotoxicity is mediated by Sarm1 and calpain activation

Aysel Cetinkaya-Fisgin, Xinghua Luan, Nicole Reed, Ye Eun Jeong, Byoung Chol Oh, Ahmet Hoke

Sci Rep. 2020; 10: 21889. Published online 2020 Dec 14. doi: 10.1038/s41598-020-78896-w

PMCID:: PMC7736304

Abstract Article PDF–2.0M

Select item 70458054.

TIR domains of plant immune receptors are NAD⁺-cleaving enzymes that promote cell death

Li Wan, Kow Essuman, Ryan G. Anderson, Yo Sasaki, Freddy Monteiro, Eui-Hwan Chung, Erin Osborne Nishimura, Aaron DiAntonio, Jeffrey Milbrandt, Jeffery L. Dangl, Marc T. Nishimura

Science. Author manuscript; available in PMC 2020 Feb 27.

Published in final edited form as: Science. 2019 Aug 23; 365(6455): 799–803. doi: 10.1126/science.aax1771

PMCID:: PMC7045805

Abstract Article PDF–720K

Select item 65319175.

A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death

Zhi Ying Zhao, Xu Jie Xie, Wan Hua Li, Jun Liu, Zhe Chen, Ben Zhang, Ting Li, Song Lu Li, Jun Gang Lu, Liangren Zhang, Li-he Zhang, Zhengshuang Xu, Hon Cheung Lee, Yong Juan Zhao

iScience. 2019 May 31; 15: 452–466. Published online 2019 May 4. doi: 10.1016/j.isci.2019.05.001

PMCID:: PMC6531917

Abstract Article PDF–6.1M

Select item 62842386.

The SARM1 Toll/Interleukin-1 Receptor (TIR) Domain Possesses Intrinsic NAD⁺ Cleavage Activity that Promotes Pathological Axonal Degeneration

Kow Essuman, Daniel W. Summers, Yo Sasaki, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt

Neuron. Author manuscript; available in PMC 2018 Dec 7.

Published in final edited form as: Neuron. 2017 Mar 22; 93(6): 1334–1343.e5. doi: 10.1016/j.neuron.2017.02.022

PMCID:: PMC6284238

Abstract Article PDF–1.2M

Select item 50682537.

SARM1-specific motifs in the TIR domain enable NAD⁺ loss and regulate injury-induced SARM1 activation

Daniel W. Summers, Daniel A. Gibson, Aaron DiAntonio, Jeffrey Milbrandt

Proc Natl Acad Sci U S A. 2016 Oct 11; 113(41): E6271–E6280. Published online 2016 Sep 26. doi: 10.1073/pnas.1601506113

PMCID:: PMC5068253

Abstract Article PDF–2.0M

Select item 50635868.

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD⁺ depletion

Yo Sasaki, Takashi Nakagawa, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt

eLife. 2016; 5: e19749. Published online 2016 Oct 13. doi: 10.7554/eLife.19749

PMCID:: PMC5063586

Abstract Article PDF–1.9M

Select item 45139509.

SARM1 activation triggers axon degeneration locally via NAD+ destruction

Josiah Gerdts, E.J. Brace, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt

Science. Author manuscript; available in PMC 2015 Jul 24.

Published in final edited form as: Science. 2015 Apr 24; 348(6233): 453–457. Published online 2015 Apr 23. doi: 10.1126/science.1258366

PMCID:: PMC4513950

Abstract Article PDF–1.5M

Select item 344340910.

Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis

Chan-Hyun Na, Drew R. Jones, Yanling Yang, Xusheng Wang, Yanji Xu, Junmin Peng

J Proteome Res. Author manuscript; available in PMC 2013 Sep 7.

Published in final edited form as: J Proteome Res. 2012 Sep 7; 11(9): 4722–4732. Published online 2012 Aug 15. doi: 10.1021/pr300536k

PMCID:: PMC3443409

Abstract Article PDF–4.2M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316686812.

Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology

Chiung-Ya Chen, Chia-Wen Lin, Chiung-Ying Chang, Si-Tse Jiang, Yi-Ping Hsueh

J Cell Biol. 2011 May 16; 193(4): 769–784. doi: 10.1083/jcb.201008050

PMCID:: PMC3166868

Abstract Article PDF–4.6M

Select item 211869313.

MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival

Younghwa Kim, Ping Zhou, Liping Qian, Jen-Zen Chuang, Jessica Lee, Chenjian Li, Costantino Iadecola, Carl Nathan, Aihao Ding

J Exp Med. 2007 Sep 3; 204(9): 2063–2074. doi: 10.1084/jem.20070868

PMCID:: PMC2118693

Abstract Article PDF–3.8M

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