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Items: 1 to 20 of 68

1.
Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB
Arturo González de la Aleja, Cristina Herrero, Mónica Torres-Torresano, María Teresa Schiaffino, Alejandro del Castillo, Bárbara Alonso, Miguel A. Vega, Amaya Puig-Kröger, Antonio Castrillo, Ángel L. Corbí
Cell Mol Life Sci. 2023 Apr; 80(4): 96. Published online 2023 Mar 17. doi: 10.1007/s00018-023-04745-4
PMCID:
PMC10020776
AbstractArticlePDF–4.5M
2.
Liver X receptor controls follicular helper T cell differentiation via repression of TCF-1
Jiyeon Kim, Haeseung Lee, Jeong-Eun Lee, Garam Choi, Hayeon Chung, Daehong Kim, Min Jung Park, Yong Seok Gye, Kwang-Soo Shin, Chang-Yuil Kang, Seung-Ki Kwok, Yeonseok Chung
Proc Natl Acad Sci U S A. 2023 Feb 28; 120(9): e2213793120. Published online 2023 Feb 21. doi: 10.1073/pnas.2213793120
PMCID:
PMC9992818
AbstractArticlePDF–1.1M
3.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
4.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
5.
Cytoplasmic LXR expression is an independent marker of poor prognosis for patients with early stage primary breast cancer
Wanting Shao, Christina Kuhn, Doris Mayr, Nina Ditsch, Magdalena Kailuwait, Verena Wolf, Nadia Harbeck, Sven Mahner, Udo Jeschke, Vincent Cavaillès, Sophie Sixou
J Cancer Res Clin Oncol. 2021; 147(9): 2535–2544. Published online 2021 Jun 3. doi: 10.1007/s00432-021-03670-y
Correction in:
J Cancer Res Clin Oncol. 2021; 147(9): 2545–2546.
PMCID:
PMC8310839
AbstractArticlePDF–1.3M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Liver X Receptor β Related to Tumor Progression and Ribosome Gene Expression in Papillary Thyroid Cancer
Seonhyang Jeong, In-Kyu Kim, Hyunji Kim, Moon Jung Choi, Jandee Lee, Young Suk Jo
Endocrinol Metab (Seoul) 2020 Sep; 35(3): 656–668. Published online 2020 Aug 20. doi: 10.3803/EnM.2020.667
PMCID:
PMC7520597
AbstractArticlePDF–1.3M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1
Deven Patel, Fahim Ahmad, Diane M. Kambach, Qian Sun, Alan S. Halim, Tamalee Kramp, Kevin A. Camphausen, Jayne M. Stommel
Sci Rep. 2019; 9: 15458. Published online 2019 Oct 29. doi: 10.1038/s41598-019-51865-8
PMCID:
PMC6820787
AbstractArticlePDF–5.8M
10.
Expression of LXR-β, ABCA1 and ABCG1 in human triple-negative breast cancer tissues
Hailing Pan, Yue Zheng, Qi Pan, Honglei Chen, Fuchun Chen, Jie Wu, Dingxin Di
Oncol Rep. 2019 Nov; 42(5): 1869–1877. Published online 2019 Aug 14. doi: 10.3892/or.2019.7279
PMCID:
PMC6775801
AbstractArticlePDF–790K
11.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
12.
Liver X receptor activation reduces gastric cancer cell proliferation by suppressing Wnt signalling via LXRβ relocalization
Qiang Wang, Fan Feng, Jiayou Wang, Meijia Ren, Zhonggang Shi, Xiang Mao, Heng Zhang, Xiaoli Ju
J Cell Mol Med. 2019 Feb; 23(2): 789–797. Published online 2018 Oct 19. doi: 10.1111/jcmm.13974
PMCID:
PMC6349166
AbstractArticlePDF–1.0M
13.
IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis
Fadhil Ahsan, Jeroen Maertzdorf, Ute Guhlich-Bornhof, Stefan H. E. Kaufmann, Pedro Moura-Alves
Sci Rep. 2018; 8: 1520. Published online 2018 Jan 24. doi: 10.1038/s41598-018-19476-x
PMCID:
PMC5784124
AbstractArticlePDF–6.1M
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
Liver X Receptor Gene Expression is Enhanced in Children with Obstructive Sleep Apnea-Hyperpnoea Syndrome and Cyclooxygenase-2 (COX-2) is Correlated with Severity of Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS)
Xin-Hua Ye, Hong Chen, Qin Yu, Qing-Ling Zhu
Med Sci Monit. 2017; 23: 3261–3268. Published online 2017 Jul 5. doi: 10.12659/MSM.900947
PMCID:
PMC5508877
AbstractArticlePDF–348K
16.
Liver X receptors agonist GW3965 re-sensitizes gefitinib-resistant human non-small cell lung cancer cell to gefitinib treatment by inhibiting NF-κB in vitro
Yong Hu, Jialan Zang, Haixia Cao, Ying Wu, Dali Yan, Xiaobing Qin, Leilei Zhou, Fan Fan, Jie Ni, Xiaoyue Xu, Huanhuan Sha, Siwen Liu, Shaorong Yu, Zhuo Wang, Rong Ma, Jianzhong Wu, Jifeng Feng
Oncotarget. 2017 Feb 28; 8(9): 15802–15814. Published online 2017 Feb 2. doi: 10.18632/oncotarget.15007
PMCID:
PMC5362524
AbstractArticlePDF–6.6M
17.
The DDX6–4E-T interaction mediates translational repression and P-body assembly
Anastasiia Kamenska, Clare Simpson, Caroline Vindry, Helen Broomhead, Marianne Bénard, Michèle Ernoult-Lange, Benjamin P. Lee, Lorna W. Harries, Dominique Weil, Nancy Standart
Nucleic Acids Res. 2016 Jul 27; 44(13): 6318–6334. Published online 2016 Jun 24. doi: 10.1093/nar/gkw565
PMCID:
PMC5291280
AbstractArticlePDF–8.8M
18.
Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells
Rohit Anthony Sinha, Brijesh K. Singh, Jin Zhou, Sherwin Xie, Benjamin L. Farah, Ronny Lesmana, Kenji Ohba, Madhulika Tripathi, Sujoy Ghosh, Anthony N. Hollenberg, Paul M. Yen
Autophagy. 2017; 13(1): 169–186. Published online 2016 Nov 15. doi: 10.1080/15548627.2016.1235123
PMCID:
PMC5240836
AbstractArticlePDF–1.9M
19.
Activation of liver X receptor attenuates lysophosphatidylcholine‐induced IL‐8 expression in endothelial cells via the NF‐κB pathway and SUMOylation
Xukun Bi, Jiale Song, Jing Gao, Juanjuan Zhao, Meihui Wang, Corey A. Scipione, Marlys L. Koschinsky, Zhao V. Wang, Shiming Xu, Guosheng Fu
J Cell Mol Med. 2016 Dec; 20(12): 2249–2258. Published online 2016 Aug 4. doi: 10.1111/jcmm.12903
PMCID:
PMC5134410
AbstractArticlePDF–1.0M
20.
Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis
Colin A. Flaveny, Kristine Griffett, Bahaa El-Dien M. El-Gendy, Melissa Kazantzis, Monideepa Sengupta, Antonio L. Amelio, Arindam Chatterjee, John Walker, Laura A. Solt, Theodore M. Kamenecka, Thomas P. Burris
Cancer Cell. Author manuscript; available in PMC 2016 Jul 28.
Published in final edited form as: Cancer Cell. 2015 Jul 13; 28(1): 42–56. Published online 2015 Jun 25. doi: 10.1016/j.ccell.2015.05.007
PMCID:
PMC4965273
AbstractArticlePDF–2.8M

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