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Select item 109332671.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 103140882.

In-depth characterisation of a cohort of individuals with missense and loss-of-function variants disrupting FOXP2

Lottie D Morison, Elisabeth Meffert, Miriam Stampfer, Irene Steiner-Wilke, Brigitte Vollmer, Katrin Schulze, Tracy Briggs, Ruth Braden, Adam Vogel, Daisy Thompson-Lake, Chirag Patel, Edward Blair, Himanshu Goel, Samantha Turner, Ute Moog, Angelika Riess, Frederique Liegeois, David A Koolen, David J Amor, Tjitske Kleefstra, Simon E Fisher, Christiane Zweier, Angela T Morgan

J Med Genet. 2023 Jun; 60(6): 597–607. Published online 2022 Nov 3. doi: 10.1136/jmg-2022-108734

PMCID:: PMC10314088

Abstract Article PDF–691K

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99888254.

Functional dissection of two amino acid substitutions unique to the human FOXP2 protein

Ulrich Bornschein, Hugo Zeberg, Wolfgang Enard, Wulf Hevers, Svante Pääbo

Sci Rep. 2023; 13: 3747. Published online 2023 Mar 6. doi: 10.1038/s41598-023-30663-3

PMCID:: PMC9988825

Abstract Article PDF–985K

Select item 98131655.

Silencing FOXP2 reverses vemurafenib resistance in BRAF^V600E mutant papillary thyroid cancer and melanoma cells

Suyuan Jiang, Yuxin Huang, Yuan Li, Qin Gu, Cuiping Jiang, Xiaoming Tao, Jiao Sun

Endocrine. 2023; 79(1): 86–97. Published online 2022 Nov 4. doi: 10.1007/s12020-022-03180-y

PMCID:: PMC9813165

Abstract Article PDF–2.1M

Select item 93629366.

A comprehensive in silico analysis of the deleterious nonsynonymous SNPs of human FOXP2 protein

Mahmuda Akter, Sumaiya Farah Khan, Abu Ashfaqur Sajib, Fahmida Sultana Rima

PLoS One. 2022; 17(8): e0272625. Published online 2022 Aug 9. doi: 10.1371/journal.pone.0272625

PMCID:: PMC9362936

Abstract Article PDF–1.1M

Select item 88288957.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 83396678.

Molecular networks of the FOXP2 transcription factor in the brain

Joery den Hoed, Karthikeyan Devaraju, Simon E Fisher

EMBO Rep. 2021 Aug 4; 22(8): e52803. Published online 2021 Jul 14. doi: 10.15252/embr.202152803

PMCID:: PMC8339667

Abstract Article PDF–1.2M

Select item 82862239.

FOXP2 expression and gray matter density in the male brains of patients with schizophrenia

Julio Sanjuán, Xochitl Helga Castro-Martínez, Gracián García-Martí, Javier González-Fernández, Roberto Sanz-Requena, Josep María Haro, J. Javier Meana, Luis Martí-Bonmatí, Juan Nacher, Noelia Sebastiá-Ortega, Javier Gilabert-Juan, María Dolores Moltó

Brain Imaging Behav. 2021; 15(3): 1403–1411. Published online 2020 Jul 30. doi: 10.1007/s11682-020-00339-x

PMCID:: PMC8286223

Abstract Article PDF–498K

Select item 824698110.

β‐catenin regulates FOXP2 transcriptional activity via multiple binding sites

Gesa Richter, Tianshu Gui, Benjamin Bourgeois, Chintan N. Koyani, Peter Ulz, Ellen Heitzer, Dirk von Lewinski, Boudewijn M. T. Burgering, Ernst Malle, Tobias Madl

FEBS J. 2021 May; 288(10): 3261–3284. Published online 2020 Dec 26. doi: 10.1111/febs.15656

PMCID:: PMC8246981

Abstract Article PDF–4.3M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 785998312.

lncRNA PART1, manipulated by transcriptional factor FOXP2, suppresses proliferation and invasion in ESCC by regulating the miR-18a-5p/SOX6 signaling axis

Yan Zhao, Qing Zhang, Hongtao Liu, Ning Wang, Xiaosan Zhang, Shujun Yang

Oncol Rep. 2021 Mar; 45(3): 1118–1132. Published online 2021 Jan 11. doi: 10.3892/or.2021.7931

PMCID:: PMC7859983

Abstract Article PDF–2.3M

Select item 725484613.

A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank

Weihua Meng, Brian W Chan, Cameron Harris, Maxim B Freidin, Harry L Hebert, Mark J Adams, Archie Campbell, Caroline Hayward, Hua Zheng, Xianwei Zhang, Lesley A Colvin, Tim G Hales, Colin N A Palmer, Frances M K Williams, Andrew McIntosh, Blair H Smith

Hum Mol Genet. 2020 May 28; 29(8): 1396–1404. Published online 2020 Apr 3. doi: 10.1093/hmg/ddaa058

PMCID:: PMC7254846

Abstract Article PDF–562K

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 694204415.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119