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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 83132392.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 71112624.

The adrenergic-induced ERK3 pathway drives lipolysis and suppresses energy dissipation

Rabih El-Merahbi, Jonathan Trujillo Viera, Angel Loza Valdes, Katarzyna Kolczynska, Saskia Reuter, Mona C. Löffler, Manuela Erk, Carsten P. Ade, Till Karwen, Alexander E. Mayer, Martin Eilers, Grzegorz Sumara

Genes Dev. 2020 Apr 1; 34(7-8): 495–510. doi: 10.1101/gad.333617.119

PMCID:: PMC7111262

Abstract Article PDF–3.7M

Select item 66555515.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Abstract Article PDF–1020K

Select item 63996666.

Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models

Mathilde Soulez, Marc K. Saba-El-Leil, Benjamin Turgeon, Simon Mathien, Philippe Coulombe, Sonia Klinger, Justine Rousseau, Kim Lévesque, Sylvain Meloche

Mol Cell Biol. 2019 Mar 15; 39(6): e00527-18. Prepublished online 2019 Jan 14. Published online 2019 Mar 1. doi: 10.1128/MCB.00527-18

PMCID:: PMC6399666

Abstract Article PDF–1.1M

Select item 44053337.

The atypical MAPK ERK3 controls positive selection of thymocytes

Julien Sirois, Jean-François Daudelin, Salix Boulet, Miriam Marquis, Sylvain Meloche, Nathalie Labrecque

Immunology. 2015 May; 145(1): 161–169. Published online 2015 Apr 14. doi: 10.1111/imm.12433

PMCID:: PMC4405333

Abstract Article PDF–834K

Select item 41356148.

The Catalytic Activity of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 3 Is Required To Sustain CD4⁺ CD8⁺ Thymocyte Survival

Miriam Marquis, Jean-François Daudelin, Salix Boulet, Julien Sirois, Karinn Crain, Simon Mathien, Benjamin Turgeon, Justine Rousseau, Sylvain Meloche, Nathalie Labrecque

Mol Cell Biol. 2014 Sep; 34(18): 3374–3387. doi: 10.1128/MCB.01701-13

PMCID:: PMC4135614

Abstract Article PDF–3.0M

Select item 39035519.

The Non-Classical MAP Kinase ERK3 Controls T Cell Activation

Miriam Marquis, Salix Boulet, Simon Mathien, Justine Rousseau, Paméla Thébault, Jean-François Daudelin, Julie Rooney, Benjamin Turgeon, Claudine Beauchamp, Sylvain Meloche, Nathalie Labrecque

PLoS One. 2014; 9(1): e86681. Published online 2014 Jan 27. doi: 10.1371/journal.pone.0086681

Correction in:: PLoS One. 2014; 9(8): e104727.

PMCID:: PMC3903551

Abstract Article PDF–1.1M

Select item 357844110.

Loss of mesenchymal CSL signaling leads to field cancerization and multifocal epithelial tumors

Bing Hu, Einar Castillo, Louise Harewood, Paola Ostano, Alexandre Reymond, Reinhard Dummer, Wassim Raffoul, Wolfram Hoetzenecker, Günther F. L. Hofbauer, G. Paolo Dotto

Cell. Author manuscript; available in PMC 2013 Jun 8.

Published in final edited form as: Cell. 2012 Jun 8; 149(6): 1207–1220. doi: 10.1016/j.cell.2012.03.048

PMCID:: PMC3578441

Abstract Article PDF–7.8M

Select item 343450011.

The Extracellular Signal-Regulated Kinase 3 (Mitogen-Activated Protein Kinase 6 [MAPK6])–MAPK-Activated Protein Kinase 5 Signaling Complex Regulates Septin Function and Dendrite Morphology

Frank Brand, Stefanie Schumacher, Shashi Kant, Manoj B. Menon, Ruth Simon, Benjamin Turgeon, Stefan Britsch, Sylvain Meloche, Matthias Gaestel, Alexey Kotlyarov

Mol Cell Biol. 2012 Jul; 32(13): 2467–2478. doi: 10.1128/MCB.06633-11

PMCID:: PMC3434500

Abstract Article PDF–2.5M

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253413.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 300426414.

Targeted Inactivation of Mapk4 in Mice Reveals Specific Nonredundant Functions of Erk3/Erk4 Subfamily Mitogen-Activated Protein Kinases

Justine Rousseau, Sonia Klinger, Adeline Rachalski, Benjamin Turgeon, Paul Déléris, Erika Vigneault, Jean-François Poirier-Héon, Maria Antonietta Davoli, Naguib Mechawar, Salah El Mestikawy, Nicolas Cermakian, Sylvain Meloche

Mol Cell Biol. 2010 Dec; 30(24): 5752–5763. Published online 2010 Oct 18. doi: 10.1128/MCB.01147-10

PMCID:: PMC3004264

Abstract Article PDF–1.7M

Select item 294751715.

ERK3 Is Required for Metaphase-Anaphase Transition in Mouse Oocyte Meiosis

Sen Li, Xiang-Hong Ou, Zhen-Bo Wang, Bo Xiong, Jing-Shan Tong, Liang Wei, Mo Li, Ju Yuan, Ying-Chun Ouyang, Yi Hou, Heide Schatten, Qing-Yuan Sun

PLoS One. 2010; 5(9): e13074. Published online 2010 Sep 29. doi: 10.1371/journal.pone.0013074

PMCID:: PMC2947517

Abstract Article PDF–5.9M

Select item 275783616.

Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality

Sonia Klinger, Benjamin Turgeon, Kim Lévesque, Geoffrey A. Wood, Kjersti M. Aagaard-Tillery, Sylvain Meloche

Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39): 16710–16715. Published online 2009 Sep 15. doi: 10.1073/pnas.0900919106

PMCID:: PMC2757836

Abstract Article PDF–2.3M

Select item 271581517.

Cdo Binds Abl To Promote p38α/β Mitogen-Activated Protein Kinase Activity and Myogenic Differentiation

Gyu-Un Bae, Bok-Geon Kim, Hye-Jin Lee, Ji-Eun Oh, Su-Jae Lee, Wei Zhang, Robert S. Krauss, Jong-Sun Kang

Mol Cell Biol. 2009 Aug; 29(15): 4130–4143. Published online 2009 May 26. doi: 10.1128/MCB.00199-09

PMCID:: PMC2715815

Abstract Article PDF–4.2M

Select item 255627018.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 122083719.

Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa.

B Turgeon, M K Saba-El-Leil, S Meloche

Biochem J. 2000 Feb 15; 346(Pt 1): 169–175.

PMCID:: PMC1220837

Summary PDF–344K

Select item 55639420.

p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

Guadalupe Sabio, James Simon Campbell Arthur, Yvonne Kuma, Mark Peggie, Julia Carr, Vicky Murray-Tait, Francisco Centeno, Michel Goedert, Nicholas A Morrice, Ana Cuenda

EMBO J. 2005 Mar 23; 24(6): 1134–1145. Published online 2005 Feb 24. doi: 10.1038/sj.emboj.7600578

PMCID:: PMC556394

Abstract Article PDF–344K

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