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Select item 115565051.

KCNB1‐Leptin receptor complexes couple electric and endocrine function in the melanocortin neurons of the hypothalamus

Elena Forzisi‐Kathera‐Ibarra, Chanmee Jo, Leonard Castillo, Anika Gaur, Prachi Lad, Alessandro Bortolami, Christian Roser, Srinidi Venkateswaran, Stefania Dutto, Matthew Selby, Harini Sampath, Ping‐Yue Pan, Federico Sesti

FASEB J. 2024 Oct 31; 38(20): e70111. Published online 2024 Oct 22. doi: 10.1096/fj.202401931R

PMCID:: PMC11556505

Abstract Article PDF–23M

Select item 113253562.

Kv2 channels do not function as canonical delayed rectifiers in spinal motoneurons

Calvin C. Smith, Filipe Nascimento, M. Görkem Özyurt, Marco Beato, Robert M. Brownstone

iScience. 2024 Aug 16; 27(8): 110444. Published online 2024 Jul 3. doi: 10.1016/j.isci.2024.110444

PMCID:: PMC11325356

Abstract Article PDF–9.1M

Select item 110248973.

Altered neurological and neurobehavioral phenotypes in a mouse model of the recurrent KCNB1-p.R306C voltage-sensor variant

Seok Kyu Kang, Nicole A. Hawkins, Christopher H. Thompson, Erin M. Baker, Dennis M. Echevarria-Cooper, Levi Barse, Tyler Thenstedt, Conor J. Dixon, Nathan Speakes, Alfred L. George, Jr, Jennifer A. Kearney

Neurobiol Dis. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Neurobiol Dis. 2024 May; 194: 106470. Published online 2024 Mar 13. doi: 10.1016/j.nbd.2024.106470

PMCID:: PMC11024897

Abstract Article PDF–2.5M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108412845.

PACSIN2 regulates platelet integrin β1 hemostatic function

Ratnashree Biswas, Emily K. Boyd, Nathan Eaton, Agata Steenackers, Marie L. Schulte, Friedrich Reusswig, Hongyin Yu, Caleb Drew, Walter H. A. Kahr, Qizhen Shi, Markus Plomann, Karin M. Hoffmeister, Hervé Falet

J Thromb Haemost. Author manuscript; available in PMC 2024 Dec 1.

Published in final edited form as: J Thromb Haemost. 2023 Dec; 21(12): 3619–3632. Published online 2023 Sep 9. doi: 10.1016/j.jtha.2023.08.026

PMCID:: PMC10841284

Abstract Article PDF–1.6M

Select item 106457486.

The formation of K_V2.1 macro-clusters is required for sex-specific differences in L-type Ca_V1.2 clustering and function in arterial myocytes

Collin Matsumoto, Samantha C. O’Dwyer, Declan Manning, Gonzalo Hernandez-Hernandez, Paula Rhana, Zhihui Fong, Daisuke Sato, Colleen E. Clancy, Nicholas C. Vierra, James S. Trimmer, L. Fernando Santana

Commun Biol. 2023; 6: 1165. Published online 2023 Nov 14. doi: 10.1038/s42003-023-05527-1

PMCID:: PMC10645748

Abstract Article PDF–6.0M

Select item 102721397.

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice

Hyoseon Oh, Suho Lee, Yusang Oh, Seongbin Kim, Young Seo Kim, Yeji Yang, Woochul Choi, Ye-Eun Yoo, Heejin Cho, Seungjoon Lee, Esther Yang, Wuhyun Koh, Woojin Won, Ryunhee Kim, C. Justin Lee, Hyun Kim, Hyojin Kang, Jin Young Kim, Taeyun Ku, Se-Bum Paik, Eunjoon Kim

Nat Commun. 2023; 14: 3547. Published online 2023 Jun 15. doi: 10.1038/s41467-023-39203-z

PMCID:: PMC10272139

Abstract Article PDF–4.3M

Select item 102089588.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 99844859.

Integrin-KCNB1 potassium channel complexes regulate neocortical neuronal development and are implicated in epilepsy

Alessandro Bortolami, Wei Yu, Elena Forzisi, Koray Ercan, Ritik Kadakia, Madhuvika Murugan, Denise Fedele, Irving Estevez, Detlev Boison, Mladen-Roko Rasin, Federico Sesti

Cell Death Differ. 2023 Mar; 30(3): 687–701. Published online 2022 Oct 7. doi: 10.1038/s41418-022-01072-2

PMCID:: PMC9984485

Abstract Article PDF–7.5M

Select item 960386010.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 951380611.

Microglial control of neuronal development via somatic purinergic junctions

Csaba Cserép, Anett D. Schwarcz, Balázs Pósfai, Zsófia I. László, Anna Kellermayer, Zsuzsanna Környei, Máté Kisfali, Miklós Nyerges, Zsolt Lele, István Katona, Ádám Dénes

Cell Rep. 2022 Sep 20; 40(12): 111369. Published online 2022 Sep 20. doi: 10.1016/j.celrep.2022.111369

PMCID:: PMC9513806

Abstract Article

Select item 928574112.

PACSIN proteins in vivo: Roles in development and physiology

Vincent Dumont, Sanna Lehtonen

Acta Physiol (Oxf) 2022 Mar; 234(3): e13783. Published online 2022 Jan 20. doi: 10.1111/apha.13783

PMCID:: PMC9285741

Abstract Article PDF–4.3M

Select item 901569913.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Abstract Article PDF–3.3M

Select item 898145714.

Cdyl Deficiency Brakes Neuronal Excitability and Nociception through Promoting Kcnb1 Transcription in Peripheral Sensory Neurons

Zhao‐Wei Sun, Jarod M. Waybright, Serap Beldar, Lu Chen, Caroline A. Foley, Jacqueline L. Norris‐Drouin, Tian‐Jie Lyu, Aiping Dong, Jinrong Min, Yu‐Pu Wang, Lindsey I. James, Yun Wang

Adv Sci (Weinh) 2022 Apr; 9(10): 2104317. Published online 2022 Feb 4. doi: 10.1002/advs.202104317

Correction in:: Adv Sci (Weinh). 2023 Sep; 10(25): 2304061.

PMCID:: PMC8981457

Abstract Article PDF–6.5M

Select item 846449815.

Kv2.1 expression in giant reticular neurons of the postnatal mouse brain

Ting Ding, Ana Maria Magarinos, Lee-Ming Kow, Teresa A. Milner, Donald W. Pfaff

J Chem Neuroanat. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: J Chem Neuroanat. 2021 Nov; 117: 102005. Published online 2021 Jul 17. doi: 10.1016/j.jchemneu.2021.102005

PMCID:: PMC8464498

Abstract Article PDF–1.1M

Select item 831323916.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 812444717.

Molecular, Cellular and Functional Changes in the Retinas of Young Adult Mice Lacking the Voltage-Gated K⁺ Channel Subunits Kv8.2 and K2.1

Xiaotian Jiang, Rabab Rashwan, Valentina Voigt, Jeanne Nerbonne, David M. Hunt, Livia S. Carvalho

Int J Mol Sci. 2021 May; 22(9): 4877. Published online 2021 May 5. doi: 10.3390/ijms22094877

PMCID:: PMC8124447

Abstract Article PDF–8.1M

Select item 811078618.

A junctional PACSIN2/EHD4/MICAL-L1 complex coordinates VE-cadherin trafficking for endothelial migration and angiogenesis

Tsveta S. Malinova, Ana Angulo-Urarte, Julian Nüchel, Marina Tauber, Miesje M. van der Stoel, Vera Janssen, Annett de Haan, Anouk G. Groenen, Merel Tebbens, Mariona Graupera, Markus Plomann, Stephan Huveneers

Nat Commun. 2021; 12: 2610. Published online 2021 May 10. doi: 10.1038/s41467-021-22873-y

PMCID:: PMC8110786

Abstract Article PDF–12M

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 786387820.

Site-specific contacts enable distinct modes of TRPV1 regulation by the potassium channel Kvβ1 subunit

Yuanyuan Wang, Xiaoyi Mo, Conghui Ping, Qian Huang, Hao Zhang, Chang Xie, Bo Zhong, Dongdong Li, Jing Yao

J Biol Chem. 2020 Dec 11; 295(50): 17337–17348. Published online 2020 Oct 15. doi: 10.1074/jbc.RA120.015605

PMCID:: PMC7863878

Abstract Article PDF–3.4M

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