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Items: 1 to 20 of 28

1.
The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
Sabelo Lukhele, Diala Abd Rabbo, Mengdi Guo, Jian Shen, Heidi J. Elsaesser, Rene Quevedo, Madeleine Carew, Ramy Gadalla, Laura M. Snell, Lawanya Mahesh, M. Teresa Ciudad, Bryan E. Snow, Annick You-Ten, Jillian Haight, Andrew Wakeham, Pamela S. Ohashi, Tak W. Mak, Weiguo Cui, Tracy L. McGaha, David G. Brooks
Immunity. Author manuscript; available in PMC 2023 Dec 13.
Published in final edited form as: Immunity. 2022 Dec 13; 55(12): 2369–2385.e10. Published online 2022 Nov 11. doi: 10.1016/j.immuni.2022.10.020
PMCID:
PMC9809269
AbstractArticlePDF–4.0M
2.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
3.
IRF2 contributes to myocardial infarction via regulation of GSDMD induced pyroptosis
Yongxing Li, Yan Wang, Hua Guo, Qinghua Wu, Yamin Hu
Mol Med Rep. 2022 Feb; 25(2): 40. Published online 2021 Dec 6. doi: 10.3892/mmr.2021.12556
PMCID:
PMC8674697
AbstractArticlePDF–5.6M
4.
IRF2 enhances RANKL-induced osteoclast differentiation via regulating NF-κB/NFATc1 signaling
Inyoung Kim, Jung Ha Kim, Kabsun Kim, Semun Seong, Keun-Bae Lee, Nacksung Kim
BMB Rep. 2021 Sep 30; 54(9): 482–487. Published online 2021 Sep 30. doi: 10.5483/BMBRep.2021.54.9.070
PMCID:
PMC8505232
AbstractArticlePDF–8.2M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon
Kana Minamide, Taku Sato, Yusuke Nakanishi, Hiroshi Ohno, Tamotsu Kato, Jumpei Asano, Toshiaki Ohteki
Sci Rep. 2020; 10: 14639. Published online 2020 Sep 8. doi: 10.1038/s41598-020-71633-3
PMCID:
PMC7479133
AbstractArticlePDF–2.8M
7.
The role of Irf6 in tooth epithelial invagination
James Blackburn, Atsushi Ohazama, Katsushige Kawasaki, Yoko Otsuka-Tanaka, Bigang Liu, Kenya Honda, Ryan B. Rountree, Yinling Hu, Maiko Kawasaki, Walter Birchmeier, Ruth Schmidt-Ullrich, Akira Kinoshita, Brian C. Schutte, Nigel L. Hammond, Michael J. Dixon, Paul T. Sharpe
Dev Biol. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Dev Biol. 2012 May 1; 365(1): 61–70. Published online 2012 Feb 14. doi: 10.1016/j.ydbio.2012.02.009
PMCID:
PMC7462630
AbstractArticlePDF–3.4M
8.
KRAS-IRF2 axis drives immune suppression and immune therapy resistance in colorectal cancer
Wenting Liao, Michael J. Overman, Adam T. Boutin, Xiaoying Shang, Di Zhao, Prasenjit Dey, Jiexi Li, Guocan Wang, Zhengdao Lan, Jun Li, Ming Tang, Shan Jiang, Xingdi Ma, Peiwen Chen, Riham Katkhuda, Krittiya Korphaisarn, Deepavali Chakravarti, Andrew Chang, Denise J. Spring, Qing Chang, Jianhua Zhang, Dipen M. Maru, Dean Y. Maeda, John A. Zebala, Scott Kopetz, Y. Alan Wang, Ronald A. DePinho
Cancer Cell. Author manuscript; available in PMC 2020 Apr 15.
Published in final edited form as: Cancer Cell. 2019 Apr 15; 35(4): 559–572.e7. Published online 2019 Mar 21. doi: 10.1016/j.ccell.2019.02.008
PMCID:
PMC6467776
AbstractArticlePDF–1.6M
9.
Interferon regulatory factor 2 inhibits expression of glycolytic genes and lipopolysaccharide induced pro-inflammatory responses in macrophages
Huachun Cui, Sami Banerjee, Sijia Guo, Na Xie, Gang Liu
J Immunol. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: J Immunol. 2018 May 1; 200(9): 3218–3230. Published online 2018 Mar 21. doi: 10.4049/jimmunol.1701571
PMCID:
PMC5915871
AbstractArticlePDF–2.3M
10.
HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections
Lei Sun, Zhengfan Jiang, Victoria A. Acosta-Rodriguez, Michael Berger, Xin Du, Jin Huk Choi, Jianhui Wang, Kuan-wen Wang, Gokhul K. Kilaru, Jennifer A. Mohawk, Jiexia Quan, Lindsay Scott, Sara Hildebrand, Xiaohong Li, Miao Tang, Xiaoming Zhan, Anne R. Murray, Diantha La Vine, Eva Marie Y. Moresco, Joseph S. Takahashi, Bruce Beutler
J Exp Med. 2017 Nov 6; 214(11): 3263–3277. doi: 10.1084/jem.20161630
PMCID:
PMC5679162
AbstractArticlePDF–1.8M
11.
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion
Melody M.H. Li, Leonia Bozzacco, Hans-Heinrich Hoffmann, Gaëlle Breton, Jakob Loschko, Jing W. Xiao, Sébastien Monette, Charles M. Rice, Margaret R. MacDonald
J Exp Med. 2016 Dec 12; 213(13): 2931–2947. doi: 10.1084/jem.20160303
PMCID:
PMC5154937
AbstractArticlePDF–2.3M
12.
Mysm1 is required for interferon regulatory factor expression in maintaining HSC quiescence and thymocyte development
X F Huang, V Nandakumar, G Tumurkhuu, T Wang, X jiang, B Hong, L Jones, H Won, H Yoshii, K Ozato, A Masumi, S-Y Chen
Cell Death Dis. 2016 Jun; 7(6): e2260. Published online 2016 Jun 9. doi: 10.1038/cddis.2016.162
PMCID:
PMC5143390
AbstractArticlePDF–3.3M
13.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
14.
Interferon regulatory factor-2 is protective against hepatic ischemia-reperfusion injury
John R. Klune, Rajeev Dhupar, Shoko Kimura, Shinya Ueki, Jon Cardinal, Atsunori Nakao, Gary Nace, John Evankovich, Noriko Murase, Allan Tsung, David A. Geller
Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1; 303(5): G666–G673. Published online 2012 Jun 28. doi: 10.1152/ajpgi.00050.2012
PMCID:
PMC3468551
AbstractArticle
15.
Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription
Hideki Hayashi, Tomoko Kohno, Kiyoshi Yasui, Hiroyuki Murota, Tohru Kimura, Gordon S. Duncan, Tomoki Nakashima, Kazuo Yamamoto, Ichiro Katayama, Yuhua Ma, Koon Jiew Chua, Takashi Suematsu, Isao Shimokawa, Shizuo Akira, Yoshinao Kubo, Tak Wah Mak, Toshifumi Matsuyama
Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46): 18766–18771. Published online 2011 Oct 31. doi: 10.1073/pnas.1116273108
PMCID:
PMC3219097
AbstractArticlePDF–1.1M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58
Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara
Dev Cell. Author manuscript; available in PMC 2011 Jun 7.
Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011
PMCID:
PMC3110151
AbstractArticlePDF–2.0M
18.
Crucial Role of Interferon Consensus Sequence Binding Protein, but neither of Interferon Regulatory Factor 1 nor of Nitric Oxide Synthesis for Protection Against Murine Listeriosis
Thomas Fehr, Gabriele Schoedon, Bernhard Odermatt, Thomas Holtschke, Markus Schneemann, Martin F. Bachmann, Tak W. Mak, Ivan Horak, Rolf M. Zinkernagel
J Exp Med. 1997 Mar 3; 185(5): 921–932. doi: 10.1084/jem.185.5.921
PMCID:
PMC2196174
AbstractArticlePDF–13M
19.
Deficiency in the Transcription Factor Interferon Regulatory Factor (Irf)-2 Leads to Severely Compromised Development of Natural Killer and T Helper Type 1 Cells
Michael Lohoff, Gordon S. Duncan, David Ferrick, Hans-Willi Mittrücker, Susi Bischof, Stefan Prechtl, Martin Röllinghoff, Edgar Schmitt, Andreas Pahl, Tak W. Mak
J Exp Med. 2000 Aug 7; 192(3): 325–336. doi: 10.1084/jem.192.3.325
PMCID:
PMC2193225
AbstractArticlePDF–205K
20.
Interferon Regulatory Factor (Irf)-1 and Irf-2 Regulate Interferon γ–Dependent Cyclooxygenase 2 Expression
Jorge C. G. Blanco, Cristina Contursi, Cindy A. Salkowski, David L. DeWitt, Keiko Ozato, Stefanie N. Vogel
J Exp Med. 2000 Jun 19; 191(12): 2131–2144. doi: 10.1084/jem.191.12.2131
PMCID:
PMC2193204
AbstractArticlePDF–429K

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