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Select item 105892971.

Hnrnpk is essential for embryonic limb bud development as a transcription activator and a collaborator of insulator protein Ctcf

Yuyu Chen, Taifeng Zhou, Zhiheng Liao, Wenjie Gao, Jinna Wu, Shun Zhang, Yongyong Li, Hengyu Liu, Hang Zhou, Caixia Xu, Peiqiang Su

Cell Death Differ. 2023 Oct; 30(10): 2293–2308. Published online 2023 Aug 22. doi: 10.1038/s41418-023-01207-z

PMCID:: PMC10589297

Abstract Article PDF–16M

Select item 93079942.

Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken

Aurélie Hintermann, Isabel Guerreiro, Lucille Lopez-Delisle, Christopher Chase Bolt, Sandra Gitto, Denis Duboule, Leonardo Beccari

Development. 2022 Jun 15; 149(12): dev200594. Published online 2022 Jun 30. doi: 10.1242/dev.200594

PMCID:: PMC9307994

Abstract Article

Select item 92058573.

Context-dependent enhancer function revealed by targeted inter-TAD relocation

Christopher Chase Bolt, Lucille Lopez-Delisle, Aurélie Hintermann, Bénédicte Mascrez, Antonella Rauseo, Guillaume Andrey, Denis Duboule

Nat Commun. 2022; 13: 3488. Published online 2022 Jun 17. doi: 10.1038/s41467-022-31241-3

PMCID:: PMC9205857

Abstract Article PDF–2.3M

Select item 85596744.

Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster

Ana Rita Amândio, Leonardo Beccari, Lucille Lopez-Delisle, Bénédicte Mascrez, Jozsef Zakany, Sandra Gitto, Denis Duboule

Genes Dev. 2021 Nov 1; 35(21-22): 1490–1509. doi: 10.1101/gad.348934.121

PMCID:: PMC8559674

Abstract Article PDF–22M

Select item 83739315.

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

Christopher Chase Bolt, Lucille Lopez-Delisle, Bénédicte Mascrez, Denis Duboule

Nat Commun. 2021; 12: 5013. Published online 2021 Aug 18. doi: 10.1038/s41467-021-25330-y

PMCID:: PMC8373931

Abstract Article PDF–3.1M

Select item 77338576.

Chromatin topology and the timing of enhancer function at the HoxD locus

Eddie Rodríguez-Carballo, Lucille Lopez-Delisle, Andréa Willemin, Leonardo Beccari, Sandra Gitto, Bénédicte Mascrez, Denis Duboule

Proc Natl Acad Sci U S A. 2020 Dec 8; 117(49): 31231–31241. Published online 2020 Nov 23. doi: 10.1073/pnas.2015083117

PMCID:: PMC7733857

Abstract Article PDF–2.5M

Select item 77046667.

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster

Yoshiki Higashijima, Nao Nagai, Masamichi Yamamoto, Taro Kitazawa, Yumiko K. Kawamura, Akashi Taguchi, Natsuko Nakada, Masaomi Nangaku, Tetsushi Furukawa, Hiroyuki Aburatani, Hiroki Kurihara, Youichiro Wada, Yasuharu Kanki

Commun Biol. 2020; 3: 725. Published online 2020 Nov 30. doi: 10.1038/s42003-020-01456-5

PMCID:: PMC7704666

Abstract Article PDF–1.3M

Select item 72599518.

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, Hiroshi Asahara

eLife. 2020; 9: e53608. Published online 2020 May 29. doi: 10.7554/eLife.53608

PMCID:: PMC7259951

Abstract Article PDF–5.5M

Select item 69694979.

The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13

Maria Félix Bastida, Rocío Pérez-Gómez, Anna Trofka, Jianjian Zhu, Alvaro Rada-Iglesias, Rushikesh Sheth, H. Scott Stadler, Susan Mackem, Marian A. Ros

Proc Natl Acad Sci U S A. 2020 Jan 14; 117(2): 1090–1096. Published online 2020 Jan 2. doi: 10.1073/pnas.1919470117

PMCID:: PMC6969497

Abstract Article PDF–1.1M

Select item 672422110.

The emergent landscape of the mouse gut endoderm at single-cell resolution

Sonja Nowotschin, Manu Setty, Ying-Yi Kuo, Vincent Liu, Vidur Garg, Roshan Sharma, Claire S. Simon, Nestor Saiz, Rui Gardner, Stéphane C. Boutet, Deanna M. Church, Pamela A. Hoodless, Anna-Katerina Hadjantonakis, Dana Pe’er

Nature. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Nature. 2019 May; 569(7756): 361–367. Published online 2019 Apr 8. doi: 10.1038/s41586-019-1127-1

PMCID:: PMC6724221

Abstract Article PDF–6.5M

Select item 662636411.

Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes

Eddie Rodríguez-Carballo, Lucille Lopez-Delisle, Nayuta Yakushiji-Kaminatsui, Asier Ullate-Agote, Denis Duboule

BMC Biol. 2019; 17: 55. Published online 2019 Jul 12. doi: 10.1186/s12915-019-0677-x

PMCID:: PMC6626364

Abstract Article PDF–1.9M

Select item 661314712.

The constrained architecture of mammalian Hox gene clusters

Fabrice Darbellay, Célia Bochaton, Lucille Lopez-Delisle, Bénédicte Mascrez, Patrick Tschopp, Saskia Delpretti, Jozsef Zakany, Denis Duboule

Proc Natl Acad Sci U S A. 2019 Jul 2; 116(27): 13424–13433. Published online 2019 Jun 17. doi: 10.1073/pnas.1904602116

PMCID:: PMC6613147

Abstract Article PDF–2.5M

Select item 591830413.

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome

Terence D. Capellini, Rediet Zewdu, Giuseppina Di Giacomo, Stefania Asciutti, Jamie E. Kugler, Anna Di Gregorio, Licia Selleri

Dev Biol. Author manuscript; available in PMC 2018 Apr 26.

Published in final edited form as: Dev Biol. 2008 Sep 15; 321(2): 500–514. Published online 2008 Apr 16. doi: 10.1016/j.ydbio.2008.04.005

PMCID:: PMC5918304

Abstract Article PDF–4.0M

Select item 513771514.

Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape

Ruben Schep, Anamaria Necsulea, Eddie Rodríguez-Carballo, Isabel Guerreiro, Guillaume Andrey, Thi Hanh Nguyen Huynh, Virginie Marcet, Jozsef Zákány, Denis Duboule, Leonardo Beccari

Proc Natl Acad Sci U S A. 2016 Nov 29; 113(48): E7720–E7729. Published online 2016 Nov 15. doi: 10.1073/pnas.1617141113