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Items: 1 to 20 of 31

1.
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development
Xiangxing Kong, Xin Shu, Jiachuan Wang, Dandan Liu, Yingchun Ni, Weiqi Zhao, Lebo Wang, Zhihua Gao, Jiadong Chen, Bing Yang, Xing Guo, Zhiping Wang
Development. 2022 Dec 15; 149(24): dev201286. Published online 2022 Dec 20. doi: 10.1242/dev.201286
PMCID:
PMC9845739
AbstractArticle
2.
Downregulation of UBE4B promotes CNS axon regrowth and functional recovery after stroke
Shuang Jin, Xiangfeng Chen, Hanyu Zheng, Wanxiong Cai, Xurong Lin, Xiangxing Kong, Yingchun Ni, Jingjia Ye, Xiaodan Li, Luoan Shen, Binjie Guo, Zeinab Abdelrahman, Songlin Zhou, Susu Mao, Yaxian Wang, Chun Yao, Xiaosong Gu, Bin Yu, Zhiping Wang, Xuhua Wang
iScience. 2023 Jan 20; 26(1): 105885. Published online 2022 Dec 26. doi: 10.1016/j.isci.2022.105885
PMCID:
PMC9840934
AbstractArticlePDF–5.2M
3.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Non-Nuclear WldS Determines Its Neuroprotective Efficacy for Axons and Synapses In Vivo
Bogdan Beirowski, Elisabetta Babetto, Jon Gilley, Francesca Mazzola, Laura Conforti, Lucie Janeckova, Giulio Magni, Richard R. Ribchester, Michael P. Coleman
J Neurosci. 2009 Jan 21; 29(3): 653–668. doi: 10.1523/JNEUROSCI.3814-08.2009
PMCID:
PMC6665162
AbstractArticlePDF–1.3M
7.
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling
Brent Wilkinson, Jing Li, Marcelo P. Coba
Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3
PMCID:
PMC5509740
AbstractArticlePDF–4.6M
8.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
9.
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis
Lea M. Starita, Jonathan N. Pruneda, Russell S. Lo, Douglas M. Fowler, Helen J. Kim, Joseph B. Hiatt, Jay Shendure, Peter S. Brzovic, Stanley Fields, Rachel E. Klevit
Proc Natl Acad Sci U S A. 2013 Apr 2; 110(14): E1263–E1272. Published online 2013 Mar 18. doi: 10.1073/pnas.1303309110
PMCID:
PMC3619334
AbstractArticlePDF–2.3M
10.
Islet α-, β-, and δ-Cell Development Is Controlled by the Ldb1 Coregulator, Acting Primarily With the Islet-1 Transcription Factor
Chad S. Hunter, Shilpy Dixit, Tsadok Cohen, Benjamin Ediger, Crystal Wilcox, Mark Ferreira, Heiner Westphal, Roland Stein, Catherine Lee May
Diabetes. 2013 Mar; 62(3): 875–886. Published online 2013 Feb 14. doi: 10.2337/db12-0952
PMCID:
PMC3581213
AbstractArticlePDF–3.7M
11.
A Novel Conserved Isoform of the Ubiquitin Ligase UFD2a/UBE4B Is Expressed Exclusively in Mature Striated Muscle Cells
Andrew L. Mammen, James A. Mahoney, Amanda St. Germain, Nisha Badders, J. Paul Taylor, Antony Rosen, Sarah Spinette
PLoS One. 2011; 6(12): e28861. Published online 2011 Dec 9. doi: 10.1371/journal.pone.0028861
PMCID:
PMC3235170
AbstractArticlePDF–2.0M
12.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
13.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
14.
Increased E4 Activity in Mice Leads to Ubiquitin-containing Aggregates and Degeneration of Hypothalamic Neurons Resulting in Obesity
Etsuo Susaki, Chie Kaneko-Oshikawa, Keishi Miyata, Mitsuhisa Tabata, Tetsuya Yamada, Yuichi Oike, Hideki Katagiri, Keiichi I. Nakayama
J Biol Chem. 2010 May 14; 285(20): 15538–15547. Published online 2010 Feb 26. doi: 10.1074/jbc.M110.105841
PMCID:
PMC2865332
AbstractArticlePDF–3.6M
15.
Structural and functional characterization of the monomeric U-box domain from E4B
Kyle A. Nordquist, Yoana N. Dimitrova, Peter S. Brzovic, Whitney B. Ridenour, Kim A. Munro, Sarah E. Soss, Richard M. Caprioli, Rachel E. Klevit, Walter J. Chazin
Biochemistry. Author manuscript; available in PMC 2011 Jan 19.
Published in final edited form as: Biochemistry. 2010 Jan 19; 49(2): 347–355. doi: 10.1021/bi901620v
PMCID:
PMC2806929
AbstractArticlePDF–2.2M
16.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
17.
Involvement of the p97-Ufd1-Npl4 Complex in the Regulated Endoplasmic Reticulum-associated Degradation of Inositol 1,4,5-Trisphosphate Receptors
Kamil J. Alzayady, Margaret M. Panning, Grant G. Kelley, Richard J. H. Wojcikiewicz
J Biol Chem. Author manuscript; available in PMC 2006 Jun 28.
Published in final edited form as: J Biol Chem. 2005 Oct 14; 280(41): 34530–34537. Published online 2005 Aug 15. doi: 10.1074/jbc.M508890200
PMCID:
PMC1483127
AbstractArticlePDF–392K
18.
Mammalian E4 Is Required for Cardiac Development and Maintenance of the Nervous System
Chie Kaneko-Oshikawa, Tadashi Nakagawa, Mitsunori Yamada, Hiroo Yoshikawa, Masaki Matsumoto, Masayoshi Yada, Shigetsugu Hatakeyama, Keiko Nakayama, Keiichi I. Nakayama
Mol Cell Biol. 2005 Dec; 25(24): 10953–10964. doi: 10.1128/MCB.25.24.10953-10964.2005
PMCID:
PMC1316961
AbstractArticlePDF–1.3M
19.
The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis.
James A Mahoney, Joseph A Odin, Sarah M White, David Shaffer, Andrew Koff, Livia Casciola-Rosen, Antony Rosen
Biochem J. 2002 Feb 1; 361(Pt 3): 587–595. doi: 10.1042/0264-6021:3610587
PMCID:
PMC1222341
SummaryPDF–622K
20.
A complex of mammalian Ufd1 and Npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways
Hemmo H. Meyer, James G. Shorter, Joachim Seemann, Darryl Pappin, Graham Warren
EMBO J. 2000 May 15; 19(10): 2181–2192. doi: 10.1093/emboj/19.10.2181
PMCID:
PMC384367
AbstractArticlePDF–1.1M

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