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Select item 102089581.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 96658852.

Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures

Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang

Neuron. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028

PMCID:: PMC9665885

Abstract Article PDF–4.5M

Select item 94819333.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74428565.

Superoxide-induced Type I Collagen Secretion Depends on Prolyl 4-Hydroxylases

Run Shi, Shanshan Gao, Andrew H. Smith, Huan Li, Ming Shao, Jianhui Shangguan, Jie Zhang, Jiang Xu, Jun Ye, Linda M. Graham, Chaoyang Li

Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Sep 3.

Published in final edited form as: Biochem Biophys Res Commun. 2020 Sep 3; 529(4): 1011–1017. Published online 2020 Jul 30. doi: 10.1016/j.bbrc.2020.07.002

PMCID:: PMC7442856

Abstract Article PDF–1.3M

Select item 69939256.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 66982057.

Ascorbate inducible N259 glycans on prolyl 4-hydroxylase subunit α1 promote hydroxylation and secretion of type I collagen

Run Shi, Weimin Hu, Yan Zhang, Shanshan Gao, Andrew H. Smith, Jun Ye, Lili Cai, Linda M. Graham, Chaoyang Li

Cell Mol Life Sci. 2019 Sep; 76(17): 3449–3464. Published online 2019 Mar 27. doi: 10.1007/s00018-019-03081-w

PMCID:: PMC6698205

Abstract Article PDF–2.9M

Select item 62980408.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 62441839.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 596105610.

Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms

Kalle H. Sipilä, Kati Drushinin, Pekka Rappu, Johanna Jokinen, Tiina A. Salminen, Antti M. Salo, Jarmo Käpylä, Johanna Myllyharju, Jyrki Heino

J Biol Chem. 2018 May 18; 293(20): 7645–7658. Published online 2018 Apr 3. doi: 10.1074/jbc.RA118.002200

PMCID:: PMC5961056

Abstract Article PDF–2.7M

Select item 538122611.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 508048412.

Overexpression of Prolyl-4-Hydroxylase-α1 Stabilizes but Increases Shear Stress-Induced Atherosclerotic Plaque in Apolipoprotein E-Deficient Mice

Xiao-qing Cao, Xin-xin Liu, Meng-meng Li, Yu Zhang, Liang Chen, Lin Wang, Ming-xue Di, Mei Zhang

Dis Markers. 2016; 2016: 1701637. Published online 2016 Oct 12. doi: 10.1155/2016/1701637

PMCID:: PMC5080484

Abstract Article PDF–2.2M

Select item 472164513.

Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning

Ilkka Pietilä, Renata Prunskaite-Hyyryläinen, Susanna Kaisto, Elisavet Tika, Albertien M. van Eerde, Antti M. Salo, Leonardo Garma, Ilkka Miinalainen, Wout F. Feitz, Ernie M. H. F. Bongers, André Juffer, Nine V. A. M. Knoers, Kirsten Y. Renkema, Johanna Myllyharju, Seppo J. Vainio

PLoS One. 2016; 11(1): e0147171. Published online 2016 Jan 21. doi: 10.1371/journal.pone.0147171

PMCID:: PMC4721645

Abstract Article PDF–5.2M

Select item 459835614.

Maternal bile acid transporter deficiency promotes neonatal demise

Yuanyuan Zhang, Fei Li, Yao Wang, Aaron Pitre, Zhong-ze Fang, Matthew W. Frank, Christopher Calabrese, Kristopher W. Krausz, Geoffrey Neale, Sharon Frase, Peter Vogel, Charles O. Rock, Frank J. Gonzalez, John D. Schuetz

Nat Commun. 2015; 6: 8186. Published online 2015 Sep 29. doi: 10.1038/ncomms9186

PMCID:: PMC4598356

Abstract Article PDF–1.5M

Select item 450544115.

Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I

Ellinoora Aro, Antti M. Salo, Richa Khatri, Mikko Finnilä, Ilkka Miinalainen, Raija Sormunen, Outi Pakkanen, Tiina Holster, Raija Soininen, Carina Prein, Hauke Clausen-Schaumann, Attila Aszódi, Juha Tuukkanen, Kari I. Kivirikko, Ernestina Schipani, Johanna Myllyharju

J Biol Chem. 2015 Jul 3; 290(27): 16964–16978. Published online 2015 May 22. doi: 10.1074/jbc.M115.662635

PMCID:: PMC4505441

Abstract Article PDF–5.2M

Select item 415802616.

An Argonaute 2 Switch Regulates Circulating miR-210 to Coordinate Hypoxic Adaptation across Cells

Andrew Hale, Changjin Lee, Sofia Annis, Pil-Ki Min, Reena Pande, Mark A. Creager, Colleen G. Julian, Lorna G. Moore, S. Alex Mitsialis, Sarah J. Hwang, Stella Kourembanas, Stephen Y. Chan

Biochim Biophys Acta. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Biochim Biophys Acta. 2014 Nov; 1843(11): 2528–2542. Published online 2014 Jun 28. doi: 10.1016/j.bbamcr.2014.06.012

PMCID:: PMC4158026

Abstract Article PDF–2.6M

Select item 407349417.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 357241018.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 348131319.

Hypoxia-inducible Factor-1 (HIF-1) but Not HIF-2 Is Essential for Hypoxic Induction of Collagen Prolyl 4-Hydroxylases in Primary Newborn Mouse Epiphyseal Growth Plate Chondrocytes

Ellinoora Aro, Richa Khatri, Rita Gerard-O'Riley, Laura Mangiavini, Johanna Myllyharju, Ernestina Schipani

J Biol Chem. 2012 Oct 26; 287(44): 37134–37144. Published online 2012 Aug 28. doi: 10.1074/jbc.M112.352872

PMCID:: PMC3481313

Abstract Article PDF–2.1M

Select item 325246520.

Oct4 links multiple epigenetic pathways to the pluripotency network

Junjun Ding, Huilei Xu, Francesco Faiola, Avi Ma'ayan, Jianlong Wang

Cell Res. 2012 Jan; 22(1): 155–167. Published online 2011 Nov 15. doi: 10.1038/cr.2011.179

PMCID:: PMC3252465

Abstract Article PDF–2.7M

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