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Select item 80948111.

Autophagy and Cell Death of Purkinje Cells Overexpressing Doppel in Ngsk Prnp‐deficient Mice

Stéphane Heitz, Nancy J. Grant, Raphael Leschiera, Anne‐Marie Haeberlé, Valérie Demais, Guy Bombarde, Yannick Bailly

Brain Pathol. 2010 Jan; 20(1): 119–132. Published online 2008 Nov 24. doi: 10.1111/j.1750-3639.2008.00245.x

PMCID:: PMC8094811

Abstract Article PDF–1.2M

Select item 75220172.

The vascular endothelial cell-expressed prion protein doppel promotes angiogenesis and blood-brain barrier development

Zhihua Chen, John E. Morales, Naze Avci, Paola A. Guerrero, Ganesh Rao, Je Hoon Seo, Joseph H. McCarty

Development. 2020 Sep 15; 147(18): dev193094. Published online 2020 Sep 23. doi: 10.1242/dev.193094

PMCID:: PMC7522017

Abstract Article

Select item 66187473.

Ataxia with Cerebellar Lesions in Mice Expressing Chimeric PrP-Dpl Protein

Catherine Lemaire-Vieille, Yannick Bailly, Paul Erlich, Corinne Loeuillet, Jacques Brocard, Anne-Marie Haeberlé, Guy Bombarde, Camille Rak, Valérie Demais, Chantal Dumestre-Pérard, Jean Gagnon, Jean-Yves Cesbron

J Neurosci. 2013 Jan 23; 33(4): 1391–1399. doi: 10.1523/JNEUROSCI.2231-12.2013

PMCID:: PMC6618747

Abstract Article PDF–3.7M

Select item 50639714.

The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain

Urška Slapšak, Giulia Salzano, Ladan Amin, Romany N. N. Abskharon, Gregor Ilc, Blaž Zupančič, Ivana Biljan, Janez Plavec, Gabriele Giachin, Giuseppe Legname

J Biol Chem. 2016 Oct 14; 291(42): 21857–21868. Published online 2016 Aug 17. doi: 10.1074/jbc.M116.743435

PMCID:: PMC5063971

Abstract Article PDF–3.2M

Select item 38735775.

The Prion Protein Modulates A-type K⁺ Currents Mediated by Kv4.2 Complexes through Dipeptidyl Aminopeptidase-like Protein 6

Robert C. C. Mercer, Li Ma, Joel C. Watts, Robert Strome, Serene Wohlgemuth, Jing Yang, Neil R. Cashman, Michael B. Coulthart, Gerold Schmitt-Ulms, Jack H. Jhamandas, David Westaway

J Biol Chem. 2013 Dec 27; 288(52): 37241–37255. Published online 2013 Nov 13. doi: 10.1074/jbc.M113.488650

PMCID:: PMC3873577

Abstract Article PDF–2.4M

Select item 38582856.

Differential Responses of Neuronal and Spermatogenic Cells to the Doppel Cytotoxicity

Kefeng Qin, Tianbing Ding, Yi Xiao, Wenyu Ma, Zhen Wang, Jimin Gao, Lili Zhao

PLoS One. 2013; 8(12): e82130. Published online 2013 Dec 10. doi: 10.1371/journal.pone.0082130

PMCID:: PMC3858285

Abstract Article PDF–1.9M

Select item 35724107.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 33995328.

The role of Bax and caspase-3 in doppel-induced apoptosis of cerebellar granule cells

Alessandro Didonna, Joshua Sussman, Federico Benetti, Giuseppe Legname

Prion. 2012 Jul 1; 6(3): 309–316. doi: 10.4161/pri.20026

PMCID:: PMC3399532

Abstract Article PDF–553K

Select item 32197229.

Protease-Resistant Prions Selectively Decrease Shadoo Protein

Joel C. Watts, Jan Stöhr, Sumita Bhardwaj, Holger Wille, Abby Oehler, Stephen J. DeArmond, Kurt Giles, Stanley B. Prusiner

PLoS Pathog. 2011 Nov; 7(11): e1002382. Published online 2011 Nov 17. doi: 10.1371/journal.ppat.1002382

PMCID:: PMC3219722

Abstract Article PDF–3.2M

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253411.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 282844812.

Genes contributing to prion pathogenesis

Gültekin Tamgüney, Kurt Giles, David V. Glidden, Pierre Lessard, Holger Wille, Patrick Tremblay, Darlene F. Groth, Fruma Yehiely, Carsten Korth, Richard C. Moore, Jörg Tatzelt, Eric Rubenstein, Claude Boucheix, Xiaoping Yang, Pamela Stanley, Michael P. Lisanti, Raymond A. Dwek, Pauline M. Rudd, Jackob Moskovitz, Charles J. Epstein, Tracey Dawson Cruz, William A. Kuziel, Nobuyo Maeda, Jan Sap, Karen Hsiao Ashe, George A. Carlson, Ina Tesseur, Tony Wyss-Coray, Lennart Mucke, Karl H. Weisgraber, Robert W. Mahley, Fred E. Cohen, Stanley B. Prusiner

J Gen Virol. Author manuscript; available in PMC 2010 Feb 24.

Published in final edited form as: J Gen Virol. 2008 Jul; 89(Pt 7): 1777–1788. doi: 10.1099/vir.0.2008/001255-0

PMCID:: PMC2828448

Abstract Article PDF–492K

Select item 282573613.

Doppel and PrP^C co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells

Anna Caputo, Daniela Sarnataro, Vincenza Campana, Maddalena Costanzo, Alessandro Negro, M. Catia Sorgato, Chiara Zurzolo

Biochem J. 2010 Jan 15; 425(Pt 2): 341–351. Prepublished online 2009 Nov 5. Published online 2009 Dec 23. doi: 10.1042/BJ20091050

PMCID:: PMC2825736

Abstract Article PDF–2.3M

Select item 270429614.

Olfactory behavior and physiology are disrupted in prion protein knockout mice

Claire E. Le Pichon, Matthew T. Valley, Magdalini Polymenidou, Alexander T. Chesler, Botir T. Sagdullaev, Adriano Aguzzi, Stuart Firestein

Nat Neurosci. Author manuscript; available in PMC 2009 Jul 1.

Published in final edited form as: Nat Neurosci. 2009 Jan; 12(1): 60–69. Published online 2008 Dec 21. doi: 10.1038/nn.2238

PMCID:: PMC2704296

Abstract Article PDF–1.1M

Select item 269366615.

Prion Protein Paralog Doppel Protein Interacts with Alpha-2-Macroglobulin: A Plausible Mechanism for Doppel-Mediated Neurodegeneration

Stefano Benvegnù, Diego Franciotta, Josh Sussman, Angela Bachi, Elisabetta Zardini, Paola Torreri, Cedric Govaerts, Salvatore Pizzo, Giuseppe Legname

PLoS One. 2009; 4(6): e5968. Published online 2009 Jun 18. doi: 10.1371/journal.pone.0005968

Correction in:: PLoS One. 2009; 4(8): 10.1371/annotation/6f581801-c5f0-4fb0-9e55-6ee35653cd12.

PMCID:: PMC2693666

Abstract Article PDF–896K

Select item 263452816.

Antagonistic roles of the N-terminal domain of prion protein to doppel

Suehiro Sakaguchi

Prion. 2008 Jul-Sep; 2(3): 107–111. doi: 10.4161/pri.2.3.7436

PMCID:: PMC2634528

Abstract Article PDF–632K

Select item 203972317.

Genes that Distinguish Physiological and Pathological Angiogenesis

Steven Seaman, Janine Stevens, Mi Young Yang, Daniel Logsdon, Cari Graff-Cherry, Brad St. Croix

Cancer Cell. Author manuscript; available in PMC 2008 Jun 1.

Published in final edited form as: Cancer Cell. 2007 Jun; 11(6): 539–554. doi: 10.1016/j.ccr.2007.04.017

PMCID:: PMC2039723

Abstract Article PDF–2.6M

Select item 195000918.

Abnormal activation of glial cells in the brains of prion protein-deficient mice ectopically expressing prion protein-like protein, PrPLP/Dpl.

R. Atarashi, S. Sakaguchi, K. Shigematsu, K. Arima, N. Okimura, N. Yamaguchi, A. Li, J. Kopacek, S. Katamine

Mol Med. 2001 Dec; 7(12): 803–809.

PMCID:: PMC1950009

Summary PDF–156K

Select item 193451919.

Doppel Induces Degeneration of Cerebellar Purkinje Cells Independently of Bax

Jiaxin Dong, Aimin Li, Naohiro Yamaguchi, Suehiro Sakaguchi, David A. Harris

Am J Pathol. 2007 Aug; 171(2): 599–607. doi: 10.2353/ajpath.2007.070262

PMCID:: PMC1934519

Abstract Article PDF–3.9M

Select item 188574020.

Physiological Expression of the Gene for PrP-Like Protein, PrPLP/Dpl, by Brain Endothelial Cells and its Ectopic Expression in Neurons of PrP-Deficient Mice Ataxic Due to Purkinje Cell Degeneration

Aimin Li, Suehiro Sakaguchi, Kazuto Shigematsu, Ryuichiro Atarashi, Bhabesh C. Roy, Ryota Nakaoke, Kazuhiko Arima, Nobuhiko Okimura, Juraj Kopacek, Shigeru Katamine

Am J Pathol. 2000 Nov; 157(5): 1447–1452. doi: 10.1016/S0002-9440(10)64782-7

PMCID:: PMC1885740

Abstract Article PDF–393K

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