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Items: 1 to 20 of 47

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis
Sung-Hee Yoon, Mark B. Meyer, Carlos Arevalo, Murat Tekguc, Chengcheng Zhang, Jialiang S. Wang, Christian D. Castro Andrade, Katelyn Strauss, Tadatoshi Sato, Nancy A. Benkusky, Seong Min Lee, Rebecca Berdeaux, Marc Foretz, Thomas B. Sundberg, Ramnik J. Xavier, Charles H. Adelmann, Daniel J. Brooks, Anthony Anselmo, Ruslan I. Sadreyev, Ivy A. Rosales, David E. Fisher, Navin Gupta, Ryuji Morizane, Anna Greka, J. Wesley Pike, Michael Mannstadt, Marc N. Wein
J Clin Invest. 2023 May 1; 133(9): e163627. Published online 2023 May 1. doi: 10.1172/JCI163627
PMCID:
PMC10145948
AbstractArticlePDF–13M
3.
An Epilepsy-Associated Mutation of Salt-Inducible Kinase 1 Increases the Susceptibility to Epileptic Seizures and Interferes with Adrenocorticotropic Hormone Therapy for Infantile Spasms in Mice
Bo Pang, Takuma Mori, Moataz Badawi, Mengyun Zhou, Qi Guo, Emi Suzuki-Kouyama, Toru Yanagawa, Yoshinori Shirai, Katsuhiko Tabuchi
Int J Mol Sci. 2022 Jul; 23(14): 7927. Published online 2022 Jul 18. doi: 10.3390/ijms23147927
PMCID:
PMC9319016
AbstractArticlePDF–1.9M
4.
Salt inducible kinases 2 and 3 are required for thymic T cell development
Meriam Nefla, Nicola J. Darling, Manuel van Gijsel Bonnello, Philip Cohen, J. Simon C. Arthur
Sci Rep. 2021; 11: 21550. Published online 2021 Nov 3. doi: 10.1038/s41598-021-00986-0
PMCID:
PMC8566462
AbstractArticlePDF–13M
5.
Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation
Christopher B. Medina, Yu-Hsin Chiu, Marta E. Stremska, Christopher D. Lucas, Ivan Poon, Kenneth S. Tung, Michael R. Elliott, Bimal Desai, Ulrike M. Lorenz, Douglas A. Bayliss, Kodi S. Ravichandran
Immunity. Author manuscript; available in PMC 2022 Aug 10.
Published in final edited form as: Immunity. 2021 Aug 10; 54(8): 1715–1727.e7. Published online 2021 Jul 21. doi: 10.1016/j.immuni.2021.06.014
PMCID:
PMC8363584
AbstractArticlePDF–2.7M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption
Cheng-Chia Tang, Christian D Castro Andrade, Maureen J O'Meara, Sung-Hee Yoon, Tadatoshi Sato, Daniel J Brooks, Mary L Bouxsein, Janaina da Silva Martins, Jinhua Wang, Nathanael S Gray, Barbara Misof, Paul Roschger, Stephane Blouin, Klaus Klaushofer, Annegreet Velduis-Vlug, Yosta Vegting, Clifford J Rosen, Daniel O'Connell, Thomas B Sundberg, Ramnik J Xavier, Peter Ung, Avner Schlessinger, Henry M Kronenberg, Rebecca Berdeaux, Marc Foretz, Marc N Wein
eLife. 2021; 10: e67772. Published online 2021 Jun 23. doi: 10.7554/eLife.67772
PMCID:
PMC8238509
AbstractArticlePDF–10M
8.
Salt-inducible kinases are required for the IL-33–dependent secretion of cytokines and chemokines in mast cells
Nicola J. Darling, J. Simon C. Arthur, Philip Cohen
J Biol Chem. 2021 Jan-Jun; 296: 100428. Published online 2021 Feb 16. doi: 10.1016/j.jbc.2021.100428
PMCID:
PMC7988334
AbstractArticlePDF–893K
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
Role of SIK1 in the transition of acute kidney injury into chronic kidney disease
Jinxiu Hu, Jiao Qiao, Qun Yu, Bing Liu, Junhui Zhen, Yue Liu, Qiqi Ma, Yanmei Li, Qianhui Wang, Cheng Wang, Zhimei Lv
J Transl Med. 2021; 19: 69. Published online 2021 Feb 15. doi: 10.1186/s12967-021-02717-5
PMCID:
PMC7885408
AbstractArticlePDF–12M
11.
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
Siwen Liu, Suling Huang, Xingde Wu, Ying Feng, Yu Shen, Qin-shi Zhao, Ying Leng
Mol Metab. 2020 Nov; 41: 101045. Published online 2020 Jun 26. doi: 10.1016/j.molmet.2020.101045
PMCID:
PMC7381706
AbstractArticlePDF–3.5M
12.
Salt-inducible Kinases Are Critical Determinants of Female Fertility
Marah Armouti, Nicola Winston, Osamu Hatano, Elie Hobeika, Jennifer Hirshfeld-Cytron, Juergen Liebermann, Hiroshi Takemori, Carlos Stocco
Endocrinology. 2020 Jul; 161(7): bqaa069. Published online 2020 Apr 28. doi: 10.1210/endocr/bqaa069
PMCID:
PMC7286620
AbstractArticle
13.
Salt-inducible kinase 1 maintains HDAC7 stability to promote pathologic cardiac remodeling
Austin Hsu, Qiming Duan, Sarah McMahon, Yu Huang, Sarah A.B. Wood, Nathanael S. Gray, Biao Wang, Benoit G. Bruneau, Saptarsi M. Haldar
J Clin Invest. 2020 Jun 1; 130(6): 2966–2977. Published online 2020 May 4. doi: 10.1172/JCI133753
PMCID:
PMC7259992
AbstractArticlePDF–8.8M
14.
Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need
Minjeong Park, Chika Miyoshi, Tomoyuki Fujiyama, Miyo Kakizaki, Aya Ikkyu, Takato Honda, Jinhwan Choi, Fuyuki Asano, Seiya Mizuno, Satoru Takahashi, Masashi Yanagisawa, Hiromasa Funato
Sci Rep. 2020; 10: 8676. Published online 2020 May 26. doi: 10.1038/s41598-020-65647-0
PMCID:
PMC7250853
AbstractArticlePDF–7.9M
15.
Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling
Shigeki Nishimori, Maureen J. O’Meara, Christian D. Castro, Hiroshi Noda, Murat Cetinbas, Janaina da Silva Martins, Ugur Ayturk, Daniel J. Brooks, Michael Bruce, Mizuki Nagata, Wanida Ono, Christopher J. Janton, Mary L. Bouxsein, Marc Foretz, Rebecca Berdeaux, Ruslan I. Sadreyev, Thomas J. Gardella, Harald Jüppner, Henry M. Kronenberg, Marc N. Wein
J Clin Invest. 2019 Dec 2; 129(12): 5187–5203. Published online 2019 Oct 22. doi: 10.1172/JCI130126
PMCID:
PMC6877304
AbstractArticlePDF–34M
16.
The AMPK-related kinases SIK1 and SIK3 mediate key tumor suppressive effects of LKB1 in NSCLC.
Pablo E. Hollstein, Lillian J. Eichner, Sonja N. Brun, Anwesh Kamireddy, Robert U. Svensson, Liliana I. Vera, Debbie S. Ross, T.J. Rymoff, Amanda Hutchins, Hector M. Galvez, April E. Williams, Maxim N. Shokhirev, Robert A. Screaton, Rebecca Berdeaux, Reuben J. Shaw
Cancer Discov. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Cancer Discov. 2019 Nov; 9(11): 1606–1627. Published online 2019 Jul 26. doi: 10.1158/2159-8290.CD-18-1261
PMCID:
PMC6825547
AbstractArticlePDF–3.0M
17.
Salt-inducible kinase 1 regulates bone anabolism via the CRTC1–CREB–Id1 axis
Min Kyung Kim, Jun-Oh Kwon, Min-Kyoung Song, Bongjun Kim, Haemin Kim, Zang Hee Lee, Seung-Hoi Koo, Hong-Hee Kim
Cell Death Dis. 2019 Nov; 10(11): 826. Published online 2019 Oct 31. doi: 10.1038/s41419-019-1915-4
PMCID:
PMC6823377
AbstractArticlePDF–8.4M
18.
STK11 is required for the normal program of ciliated cell differentiation in airways
Qiqi Chu, Changfu Yao, Xiangbing Qi, Barry Raymond Stripp, Nan Tang
Cell Discov. 2019; 5: 36. Published online 2019 Jul 16. doi: 10.1038/s41421-019-0104-z
PMCID:
PMC6796922
AbstractArticlePDF–4.6M
19.
Transcriptional analysis of Foxp3+ Tregs and functions of two identified molecules during resolution of ALI
Jason R. Mock, Catherine F. Dial, Miriya K. Tune, Dustin L. Norton, Jessica R. Martin, John C. Gomez, Robert S. Hagan, Hong Dang, Claire M. Doerschuk
JCI Insight. 2019 Mar 21; 4(6): e124958. Published online 2019 Mar 21. doi: 10.1172/jci.insight.124958
PMCID:
PMC6482998
AbstractArticlePDF–4.3M
20.
Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis
Esther Paulo, Dongmei Wu, Yangmeng Wang, Yun Zhang, Yixuan Wu, Danielle L. Swaney, Margaret Soucheray, David Jimenez-Morales, Ajay Chawla, Nevan J. Krogan, Biao Wang
Sci Rep. 2018; 8: 11001. Published online 2018 Jul 20. doi: 10.1038/s41598-018-29333-6
PMCID:
PMC6054673
AbstractArticlePDF–6.6M

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