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Items: 1 to 20 of 113

1.
Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance
Aya Ushio, Mami Matsuda-Lennikov, Felix Kalle-Youngoue, Akihide Shimizu, Abdalla Abdelmaksoud, Michael C. Kelly, Naozumi Ishimaru, Yousuke Takahama
Cell Rep. Author manuscript; available in PMC 2024 May 9.
Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 114072. Published online 2024 Apr 5. doi: 10.1016/j.celrep.2024.114072
PMCID:
PMC11079940
AbstractArticlePDF–3.1M
2.
RelB-deficient autoinflammatory pathology presents as interferonopathy, but in mice is IFN-independent
Hector I. Navarro, Yi Liu, Anna Fraser, Diane Lefaudeux, Jennifer J. Chia, Linda Vong, Chaim M. Roifman, Alexander Hoffmann
J Allergy Clin Immunol. Author manuscript; available in PMC 2024 Feb 10.
Published in final edited form as: J Allergy Clin Immunol. 2023 Nov; 152(5): 1261–1272. Published online 2023 Jul 15. doi: 10.1016/j.jaci.2023.06.024
PMCID:
PMC10858800
AbstractArticlePDF–1.9M
3.
Embryonic keratin19+ progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla
Beth Lucas, Andrea J. White, Fabian Klein, Clara Veiga-Villauriz, Adam Handel, Andrea Bacon, Emilie J. Cosway, Kieran D. James, Sonia M. Parnell, Izumi Ohigashi, Yousuke Takahama, William E. Jenkinson, Georg A. Hollander, Wei-Yu Lu, Graham Anderson
Nat Commun. 2023; 14: 2066. Published online 2023 Apr 12. doi: 10.1038/s41467-023-37589-4
PMCID:
PMC10097809
AbstractArticlePDF–8.2M
4.
EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice
Zili Lei, Wanwan Liu, Ya Nie, Yanhong Yang, Guibin Chen, Li Huang, Huijuan Wu, Yuting Lei, Lei Chen, Qing Hu, Hedong Rong, Siping Yu, Qi Song, Fengxue Tong, Jiao Guo
Front Immunol. 2022; 13: 843378. Published online 2022 Apr 13. doi: 10.3389/fimmu.2022.843378
PMCID:
PMC9043958
AbstractArticlePDF–8.1M
5.
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
Francesco Borriello, Valentina Poli, Ellen Shrock, Roberto Spreafico, Xin Liu, Novalia Pishesha, Claire Carpenet, Janet Chou, Marco Di Gioia, Marisa E. McGrath, Carly A. Dillen, Nora A. Barrett, Lucrezia Lacanfora, Marcella E. Franco, Laura Marongiu, Yoichiro Iwakura, Ferdinando Pucci, Michael D. Kruppa, Zuchao Ma, Douglas W. Lowman, Harry E. Ensley, Etsuro Nanishi, Yoshine Saito, Timothy R. O’Meara, Hyuk-Soo Seo, Sirano Dhe-Paganon, David J. Dowling, Matthew Frieman, Stephen J. Elledge, Ofer Levy, Darrell J. Irvine, Hidde L. Ploegh, David L. Wiliams, Ivan Zanoni
Cell. Author manuscript; available in PMC 2023 Feb 17.
Published in final edited form as: Cell. 2022 Feb 17; 185(4): 614–629.e21. Published online 2022 Feb 10. doi: 10.1016/j.cell.2022.01.009
PMCID:
PMC8857056
AbstractArticlePDF–2.1M
6.
TIFAB accelerates MLL-AF9−Induced acute myeloid leukemia through upregulation of HOXA9
Jinming Zhao, Yan Xiu, Lin Fu, Qianze Dong, Nicholas Borcherding, Yang Wang, Qingchang Li, Nilushi S. De Silva, Ulf Klein, Brendan F. Boyce, Chen Zhao
iScience. 2021 Dec 17; 24(12): 103425. Published online 2021 Nov 12. doi: 10.1016/j.isci.2021.103425
PMCID:
PMC8633042
AbstractArticlePDF–2.2M
7.
A T cell-intrinsic function for NF-κB RelB in experimental autoimmune encephalomyelitis
Guilhem Lalle, Raphaëlle Lautraite, Allison Voisin, Julie Twardowski, Pierre Stéphan, Marlène Perrin-Niquet, Ramdane Igalouzene, Saidi M. Soudja, Julien C. Marie, Marc Vocanson, Nilushi De Silva, Ulf Klein, Sankar Ghosh, Yenkel Grinberg-Bleyer
Sci Rep. 2021; 11: 19674. Published online 2021 Oct 4. doi: 10.1038/s41598-021-99134-x
PMCID:
PMC8490410
AbstractArticlePDF–4.6M
8.
Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF
Annika Hausmann, Boas Felmy, Leo Kunz, Sanne Kroon, Dorothée Lisa Berthold, Giverny Ganz, Ioana Sandu, Toshihiro Nakamura, Nathan Sébastien Zangger, Yang Zhang, Tamas Dolowschiak, Stefan Alexander Fattinger, Markus Furter, Anna Angelika Müller-Hauser, Manja Barthel, Katerina Vlantis, Laurens Wachsmuth, Jan Kisielow, Luigi Tortola, Danijela Heide, Mathias Heikenwälder, Annette Oxenius, Manfred Kopf, Timm Schroeder, Manolis Pasparakis, Mikael Erik Sellin, Wolf-Dietrich Hardt
J Exp Med. 2021 Nov 1; 218(11): e20210862. Published online 2021 Sep 16. doi: 10.1084/jem.20210862
PMCID:
PMC8480669
AbstractArticlePDF–7.9M
9.
E3 ligase c-Cbl regulates intestinal inflammation through suppressing fungi-induced noncanonical NF-κB activation
Jie-Lin Duan, Hui-Qian He, Yao Yu, Tao Liu, Shu-Jun Ma, Fan Li, Yan-Shan Jiang, Xin Lin, De-Dong Li, Quan-Zhen Lv, Hui-Hui Ma, Xin-Ming Jia
Sci Adv. 2021 May; 7(19): eabe5171. Published online 2021 May 7. doi: 10.1126/sciadv.abe5171
PMCID:
PMC8104877
AbstractArticlePDF–9.3M
10.
The transcription factor RelB restrains group 2 innate lymphoid cells and type 2 immune pathology in vivo
Lei Zhang, Yuanlin Ying, Shuqiu Chen, Preston R. Arnold, Fafa Tian, Laurie J. Minze, Xiang Xiao, Xian C. Li
Cell Mol Immunol. 2021 Jan; 18(1): 230–242. Published online 2020 Mar 19. doi: 10.1038/s41423-020-0404-0
PMCID:
PMC7852540
AbstractArticlePDF–5.6M
11.
Lung IFNAR1hi TNFR2+ cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state
Samira Mansouri, Divya S. Katikaneni, Himanshu Gogoi, Mauricio Pipkin, Tiago N. Machuca, Amir M. Emtiazjoo, Lei Jin
Mucosal Immunol. 2020; 13(4): 595–608. Published online 2020 Jan 20. doi: 10.1038/s41385-020-0254-1
PMCID:
PMC7311323
AbstractArticlePDF–4.1M
12.
RelB regulates the homeostatic proliferation but not the function of Tregs
Shuping Zhou, Weiwei Wu, Zhaoxia Wang, Zhaopeng Wang, Qinghong Su, Xiaofan Li, Yong Yu, Weidong Zhang, Mingzhao Zhu, Wei Lin
BMC Immunol. 2020; 21: 37. Published online 2020 Jun 18. doi: 10.1186/s12865-020-00366-9
PMCID:
PMC7302365
AbstractArticlePDF–2.2M
13.
RelB promotes liver fibrosis via inducing the release of injury‐associated inflammatory cytokines
Danhua Zhou, Wei Huang, Jinhuan Wei, Jingxin Zhang, Zhaoxiu Liu, Ran Ji, Sijia Ge, Mingbing Xiao, Yihui Fan, Cuihua Lu
J Cell Mol Med. 2020 Jun; 24(11): 6008–6014. Published online 2020 Apr 19. doi: 10.1111/jcmm.15108
PMCID:
PMC7294124
AbstractArticlePDF–1.1M
14.
Avian Reticuloendotheliosis Viral Oncogene Related B Regulates Lymphatic Endothelial Cells during Vessel Maturation and Is Required for Lymphatic Vessel Function in Adult Mice
Qianqian Liang, Li Zhang, Ronald W. Wood, Rui-Cheng Ji, Brendan F. Boyce, Edward.M. Schwarz, Yongjun Wang, Lianping Xing
Am J Pathol. 2019 Dec; 189(12): 2516–2530. doi: 10.1016/j.ajpath.2019.08.009
PMCID:
PMC6893922
AbstractArticlePDF–2.7M
15.
RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells
Nico Andreas, Maria Potthast, Anna-Lena Geiselhöringer, Garima Garg, Renske de Jong, Julia Riewaldt, Dennis Russkamp, Marc Riemann, Jean-Philippe Girard, Simon Blank, Karsten Kretschmer, Carsten Schmidt-Weber, Thomas Korn, Falk Weih, Caspar Ohnmacht
J Immunol. 2019 Nov 15; 203(10): 2602–2613. Published online 2019 Oct 2. doi: 10.4049/jimmunol.1801530
PMCID:
PMC6826119
AbstractArticlePDF–1.4M
16.
Switch of NAD Salvage to de novo Biosynthesis Sustains SIRT1-RelB-Dependent Inflammatory Tolerance
Jingpu Zhang, Jie Tao, Yun Ling, Feng Li, Xuewei Zhu, Li Xu, Mei Wang, Shuye Zhang, Charles E. McCall, Tie Fu Liu
Front Immunol. 2019; 10: 2358. Published online 2019 Oct 11. doi: 10.3389/fimmu.2019.02358
PMCID:
PMC6797595
AbstractArticlePDF–1.2M
17.
Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
Yuzhu Hou, Hua Liang, Enyu Rao, Wenxin Zheng, Xiaona Huang, Liufu Deng, Yuan Zhang, Xinshuang Yu, Meng Xu, Helena Mauceri, Ainhoa Arina, Ralph R. Weichselbaum, Yang-Xin Fu
Immunity. Author manuscript; available in PMC 2019 Oct 3.
Published in final edited form as: Immunity. 2018 Sep 18; 49(3): 490–503.e4. Published online 2018 Aug 28. doi: 10.1016/j.immuni.2018.07.008
PMCID:
PMC6775781
AbstractArticlePDF–1.0M
18.
IκB Kinase/Nuclear Factor κB-Dependent Insulin-Like Growth Factor 2 (Igf2) Expression Regulates Synapse Formation and Spine Maturation via Igf2 Receptor Signaling
Michael J. Schmeisser, Bernd Baumann, Svenja Johannsen, Gry F. Vindedal, Vidar Jensen, Øivind C. Hvalby, Rolf Sprengel, Jochen Seither, Ayesha Maqbool, Alexander Magnutzki, Michael Lattke, Franz Oswald, Tobias M. Boeckers, Thomas Wirth
J Neurosci. 2012 Apr 18; 32(16): 5688–5703. doi: 10.1523/JNEUROSCI.0111-12.2012
PMCID:
PMC6703485
AbstractArticlePDF–3.8M
19.
A detrimental role of RelB in mature oligodendrocytes during experimental acute encephalomyelitis
Angela S. Gupta, Debolina D. Biswas, La Shardai N. Brown, Karli Mockenhaupt, Michael Marone, Andrew Hoskins, Ulrich Siebenlist, Tomasz Kordula
J Neuroinflammation. 2019; 16: 161. Published online 2019 Jul 30. doi: 10.1186/s12974-019-1548-7
PMCID:
PMC6664766
AbstractArticlePDF–2.6M
20.
RelB controls adaptive responses of astrocytes during sterile inflammation
Angela S. Gupta, Michael R. Waters, Debolina D. Biswas, Lashardai N. Brown, Michael J. Surace, Constantinos Floros, Ulrich Siebenlist, Tomasz Kordula
Glia. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Glia. 2019 Aug; 67(8): 1449–1461. Published online 2019 Apr 7. doi: 10.1002/glia.23619
PMCID:
PMC6557670
AbstractArticlePDF–1.0M

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